BIO 313 Exam 4 Review A Supplemental Instruction Iowa State University Leader: Course: Instructor: Date: Laura Bio 313 Dr. Rodermel 11/11/15 CHAPTER 16 1. What is the difference between a structural gene and regulator gene? a. Structural genes are transcribed into mRNA, but regulator genes aren’t b. Structural genes have complex structures; regulator genes have simple structures c. Structural genes encode proteins that function in the structure of the cell; regulator genes carry out metabolic reactions d. Structural genes encode proteins; regulator genes control the transcription of structural genes 2. In a negative repressibke operon, the regulator protein is synthesized as a. An active activator b. An inactive activator c. An active repressor d. An inactive repressor 3. In the presence of allolactose, the lac repressor a. Binds to the operator b. Bonds to the promoter c. Cannot bind to the operator d. Binds to the regulator gene 4. What is the effect of high levels of glucose on the lac operon? a. Tx is stimulated b. Little Tx takes place c. Tx is not affected d. Tx may be stimulated or inhibited, depending on the levels of lactose 5. Complete the following table Type Location Cis/Trans Effect Only affect lacZ and lacY Structural Gene Mutation Affects transcription of Structural Genes Regulator Gene Mutation lacO Promoter Mutation Cis 1060 Hixson-Lied Student Success Center 515-294-6624 sistaff@iastate.edu http://www.si.iastate.edu CHAPTER 17 6. Most transcriptional activator proteins affect transcription by interacting with a. Introns b. The basal tx apparatus c. DNA polymerase d. The terminator 7. In RNA silencing, siRNAs and miRNAs usually bind to which part of the mRNA molecules that they control? a. 5’ UTR b. Segment that encodes amino acids c. 3’ PolyA tail d. 3’ UTR 8. All of the following are differences between prokaryotic and eukaryotic gene regulation except a. Prokaryotes use operons b. Prokaryotes tx and tl are coupled c. Prokaryotes contain histones d. Eukaryotes use cap binding proteins and PABPs 9. List the six levels of gene regulation a. b. c. d. e. f. 10. The purpose of gene regulation is a. Control mRNA processing b. Modify DNA c. Fold amino acid sequence into appropriate quaternary structure d. Produce precise amount of protein from a given gene 11. Which of the following is false about response elements? a. Are also known as boxes b. They are gene specific c. They are located in the regulatory promoter d. They bind silencers 12. List the 11 key points of gene regulation 1. 7. 2. 8. 3. 9. 4. 10. 5. 11. 6. CHAPTER 2 13. The period between Meiosis I and Meiosis II is known as a. Prophase II b. Cytokinesis c. Interkinesis d. Metaphase II 14. Diploid cells have a. Two chormosomes b. Two sets of chromosomes c. One set of chromosomes d. Two pairs of homologous chromosomes 15. Which is the correct order of stages in the cell cycle? a. G1, S, prophase, metaphase, anaphase b. S, G1, prophase, metaphase, anaphase c. Prophase, S, G1, metaphase, anaphase d. S, G1, anaphase, prophase, metaphase 16. Which of the following takes place in metaphase I? a. Crossing over b. Chromosomes contract c. Homologous pairs of chromosomes line up on the metaphase plate d. Individual chromosomes line up on the metaphase plate 17. A secondary spermatocyte has 12 chromosomes. How many chromosomes will be found in the primary spermatocyte that gave rise to it? a. 6 b. 12 c. 18 d. 24 18. Which structure is diploid? a. Microspore b. Megaspore c. Egg d. Microsporocyte 19. Which of the following are found in Eukaryotes and not Prokaryotes a. Cell Wall b. Ribosomes c. Membrane-bound Organelles d. Plasma Membrane 20. Interphase consists of all the following phases EXCEPT a. M Phase b. G2 Phase c. S Phase d. G1 Phase 21. This phase consists of biochemical preparation for cell division a. M Phase b. G2 Phase c. S Phase d. G1 Phase 22. This phase consists of DNA synthesis a. M Phase b. G2 Phase c. S Phase d. G1 Phase 23. Which phase of mitosis is depicted below? a. b. c. d. Anaphase Telophase Metaphase Prophase 24. Which is true about mitosis? a. Produces 2 genetically different cells b. Each cell contains the total amount of cytoplasm needed c. New cells contain a full complement of chromosomes d. Cells start as diploid and end as haploid 25. Meiosis I is defined by a. DNA synthesis b. Reduction of chromosome number in half c. Separation of sister chromatids d. Goes through equatorial division 26. Prophase I consist of all of the following except a. Tetrads are present b. Synapsis occurs c. Crossing over occurs d. Cytokinesis occurs 27. Which phase of meiosis is shown below? a. Metaphase I b. Prophase II c. Anaphase II d. Metaphase II 28. Which phase of meiosis is shown below? a. b. c. d. Metaphase I Prophase II Anaphase II Metaphase II 29. Which of the following events take place in meiosis II, but not meiosis I? a. Chromosomes contract b. Homologous chromosomes separate c. Crossing over d. Chromatids separate CHAPTER 3 30. Which of the following factors did not contribute to Mendel’s success in his study of heredity? a. His use of the pea plant b. His study of plant chromosomes c. His adoption of an experimental approach d. His use of mathematics 31. If an F1 plant depicted in Figure 3.5 is backcrossed to the parent with round seeds, what proportion of the progeny will have wrinkled seeds? a. ¾ b. ½ c. ¼ d. 0 30. Match the term to the definition ___ Gene A. Specific place on a chromosome occupied by an allele ___ Allele B. An individual organism possessing two different alleles at a locus ___ Locus C. An attribute or feature possessed by an organism ___ Genotype D. The appearance or manifestation of a characteristic ___ Phenotype E. An individual organism possessing two of the same alleles at a locus ___ Homozygous F. An inherited factor that helps determine a characteristic ___ Heterozygous G. One of two or more alternative forms of a gene ___ Characteristic H. Set of alleles possessed by an individual organism 31. Beginning with a Oogonium and spermatogonium draw the processes that will reach a zygote, include ploidy levels: