Exercise & Clinical Medicine Bruce Helming, MD Objectives: Define Exercise Benefits/Risks Pre-participation Evaluation How to Assess Readiness for Change Helping to Motivate Exercise Prescription (writing one) Exercise for aging/arthritis/depression Some Facts: - 200,000 deaths occur per year because of a sedentary life style - 25% of people state they do no exercise - 15% of people state they do minimal exercise - Women, blacks, Hispanics, elderly, low income most likely not to exercise - Physicians done ask about exercise!! Def. Of Exercise: Denotes regular physical activity that is planned, structures, repetitive, purposeful, and is for the improvement/ maintenance of physical fitness. - Vs. physical activity which could include cleaning etc Benefits of exercise: Muscular skeletal: Increases muscle fiber, capillary density, muscle, bone, ligament length Metabolic: Increases mitochondria, muscle glycogen storage, muscle fat utilization, Vo2 and lactate threshold Cardiovascular: Increases, SV, CO, contractility (hypertrophy), plasma volume, capillary flow, endothelial function (dilation), and HR variability Also, Decreases resting HR, BP (especially in hypertensives *Hypertrophy from exercise is different than LVH from hypertension! Respiratory: Increases respiratory rate, tital volume, pulmonary blood flow Immune system: moderate exercise will increase the functioning, while intense exercise has an adverse effect Endocrine: Decreases serum insulin levels and secretion Other benefits: Increased: glycemic control, lipid profile, HDL Decreased: coronary disease, cardiac events, medical costs, death (allcause mortality), Type 2 diabetes A Study: 10,269 Harvard alumni -Those who were moderately active had a 23% decrease in mortality Decreased: risk of thrombosis, stroke (ischemic and hemorrhagic), obesity - Moderate exercise was found to facilitate smoking cessation in females - Decreased the risk of symptomatic gallstones Benefits for the elderly - Decreased disability - Increased autonomy, functional status - Preserves bone density - Delays/slows cognitive decline More Benefits! Aids with self esteem in adolescents, asthma, HIV, AIDS, pregnancy, low back pain, neuropathy, chronic fatigue, sleep, panic disorder, dizziness, etc!! Risks of exercise: 1. Muscular skeletal injury - Strains, tears, inflammation, chronic strain, stress fractures, nerve palsies, tendonitis, bursitis - #1 injury is sprains - Ice is the most potent anti-inflammatory treatment available 2. Arrhythmia - Training reduces risk, acute exercise increases risk 3. MI - There is a temporary increased risk with infrequent exercisers with multiple cardiac risk (2-10 fold increase! - Regular exercise is still protective against MI 4. Sudden Death - Jogging has the risk of 1 death per 396,000 hrs - Health clubs risk is 1 per 887,526 hrs - Vigorous exercise (up to 30 min after cessation) the risk is 16.9 (hrs not given) - There is only 1 death per 1.51 million episodes of exercise Causes of sudden death: a. Under 35, Hypertrophic Cardiac Myopathy b. Over 35, Coronary a. disease 5. Rhabdomyolysis- muscle breakdown - Labs would show: myoglobinemia, myoglobinuria, elevated serum CPK (CK) creatine phosphokinase - Occurs following exertion - Risk factors: untrained, heat, humidity, sickle cell trait, hypokalemia - Presents with dark urine - Condition can be normal, but enough will cause renal failure, can progress to death - In early stages can be treated with hydration Risks Cont. 6. Bronchoconstriction - Exacerbates symptoms in 70% of asthmatics - Exercise induced bronchospasm (EIB) – onset 8-10 min. post-activity because of a decrease in epinephrine and adrenaline - Treatment: inhaler, steroids 7. Heat/cold illness 8. Dehydration 9. Female athlete Triad – Disordered eating, amenorrhea, osteoporosis 10. Immunosuppression, urticaria, anaphylaxis The benefits outweigh the risks!! Even after a heart attack and in advanced stage illnesses the patient should ALWAYS be doing SOMETHING. Exercise Prescription: Ask about: physical activity, exercise, barriers to exercise, benefits of exercise Recommend: ‘30 minutes of moderate exercise most days of the week’ The Goal: Exercising 5-6 days per week, 30 minutes per day at 70-80% of maximum HR (220-age) focusing on aerobic exercise and the risk/benefit ratio of the individual - This will increase HDL and is cardioprotective For Weight Loss: Exercising 5-6 days per week, 45- 60 minutes per day at 60% of max. HR - For aerobic, start with 15 minutes, and increase by one minute per session until you build up to required time - Fatty acid utilization improves with conditioning! For Arthritis: Exercise 5-6 days per week for 30 minutes each day at 70- 80% of the max HR. Focus on low impact, but you need to “load joint:” Deconditioning Joint protection Joint Damage - You want to build the muscles around the joint to protect it, but also avoid pain - Suggest walking, jogging, bicycle - Patient must get through the threshold of pain when they first start and then they will be creating joint protection Nutrition: - suggest balanced diet, carbs, protein, fat, fluid replacement, carb. Replacement after exercise Avoid fad diets and restriction diets Stages of Change Precontemplative – not aware of risky behavior, no intent to change in future Contemplative – aware of risky behavior, foresees a point in the distant future when they might change Preparation- will take action in the near future Action- actually modifying the behavior, requires time and energy Maintenance- taking various measures to keep the behavior from returning Motivational Interviewing: - Remember change is internal, the goal is the elicit change self talk, you should be nonjudgmental, supportive and reflective. - Ask: How important is exercise? 1- 10 ; What are the benefits of NOT exercising? The Barriers? How can we overcome them? - Respect patient autonomy, offer support, empathy, don’t take responsibility, your job is to help them help themselves! More on Sudden Death - 10 –13 annual occurrences - 1: 100,00 – 300,000 HS athletes - 1:15,000 joggers - 1:50,000 marathoners (every year NY marathon expects someone to die!) - Occurs in M > F - Most ‘dangerous’ sports for sudden death: 1. Basketball 2. Football 3. (distant third) track #1 cause is Hypertrophic Cardial Myopathy (most common in young adult) - Septal hypertrophy that decreases the rt. ventricle capacity and puts pressure on the mitral valve - Cause: coronary a. anomaly, a history of Marfan, long QT, carditis, murmers - Most patients are asymptomatic, but some may be dizzy with exercise, history of fainting, chest pain - Screen with ECG and a history - Treatment: have to stop exercising or ICD Screening for exercise - After 35, screening is necessary for new exercisers (coronary a. disease, Family history of premature CVD - Stress tests: start at age 40 for males, and 50 for females or 65 for athletes Mononucleosis - Airway obstruction and splenic enlargement/ rupture that occurs 4-21 days after infection - Patients should be kept from exercising for 3-4 wks, and can expect a full return after wk 5 Acute Febrile Illness - Restrict activities especially with GI illness which may cause increased risk of dehydration and thermo problems Blood Borne Pathogens - HIV – the only sport that excludes is boxing - If patient feels well, then exercise is ok Osteoarthritis - Progressive but can be stabilized with exercise Avoidance of activity leads to weakness, which leads to joint instability Management: NSAIDS, topical analgesics, steroids injections, opioid analgesics Extreme Exercise - Exercise addiction - Increased Injuries - Risk of overtraining