Charlottesville, VA 22903
Career Portfolio provided by Beyond.com
Member Number: 5090345
Portfolio: http://www.beyond.com/people/5090345
Job Function: Science & Biotech, Healthcare & Medical, Research
Education: Post Graduate Degree
Experience: 3 – 5 Years
Employment: Full-Time
Salary: $80-100k
Security Clearance: Active Confidential
Citizenship: Non U.S. Citizen
***
OBJECTIVE
Bioanalytical /Biotechnology or associated research scientist position in a R&D department.
SUMMARY OF QUALIFICATIONS
* 7+ years demonstrated, effective research with strong interdisciplinary Bioanalytical Chemistry, Biotechnology and
Biophysics skills and a background reflecting consistent research progression and achievement of objectives.
* Breadth of research experience and scientific acumen attest to an ability to fully utilize resources and effect results that are profitable to the company.
* Keen observation and intellectual abilities facilitate understanding of all facets in the problem-solving process.
AREAS OF STRENGTH
* Protein Expression and Purification
* Protein NMR for Structure Determination
* Protein Monolithic Digestion

scientist
* Peptide Monolithic uHPLC
* DNA Analysis
* New HPLC Stationary Phase Development
* Monolith Development and Evaluation
* Monolith Surface Functional Derivatization
* Microfluidic Clinical/Biomedical Application
* Capillary Electrophoresis
PROFESSIONAL EXPERIENCE
BIOPHYSICS (*** ***)
* Hands-on experience in target proteins expression and purification using various biological techniques. Recorded multidimensional NMR experiments for protein 3D structure determination. Completed sequential NMR assignments and collected structure constrains for protein structure calculation.
* Mapping protein-protein interactions by NMR spectroscopy using chemical shift perturbation technique. Investigated the structure and dynamics of biological macromolecules in solution.
BIOANALYTICAL CHEMISTRY / BIOTECHNOLOGY (*** - Present)
* Excellent experience in new solid phase development. Full understand of the state-of-the-art monolith technique for LC packing. Proficient in monolithic phase formation, surface derivatization and performance evaluation. Extensive ability in
HPLC stationary phase development.
* Excellent laboratory skills and good background in biological and physical sciences. Effective research in protein digestion and separation. Developed and optimized monolithic phase for enzyme immobilization using encapsulation and coating techniques. Designed and functionalized reverse phase monolith for peptide uHPLC. Developed chromatography methods especially for microfluidic devices.
* Demonstrated experience in nucleic acids isolation, stabilization, purification and amplification from crude biological samples. Optimized grafted monolithic phase with high DNA binding affinity. Developed a novel monolithic microdevice with two thousand fold increase in capacity for clinical applications.
* Demonstrated skill in microfluidic device design and fabrication, particularly for glass microchips. Excellent experience in sample preparation, purification and pre-concentration on microfluidics for bioanalytical, biomedical and clinical applications.
EDUCATION

scientist
UNIVERSITY OF VIRGINIA, Charlottesville, VA
Ph.D. candidate of Interdisciplinary Program in Biophysics (expected ***)
WUHAN UNIVERSITY, Wuhan, ***a
M.S. of Biological Chemistry******
B.S. of Analytical Chemistry******
B.E. of Computer Science******
SELECTED PUBLICATIONS
*** *** ***; Cui Yanfang; Hung Sze Kong; Man David; Lin Donghai; Liu Maili; Zhu Guang Interaction between calcium-free calmodulin and IQ motif of neurogranin studied by nuclear magnetic resonance spectroscopy. Analytical Biochemistry,
(***), ***, ***
*** *** ***; Guillo Christelle; Ferrance Jerome P; Landers James P. DNA Extraction Using a Tetramethyl Orthosilicate-
Grafted Photopolymerized Monolithic Solid Phase. Analytical Chemistry, (***), ***, ***
*** *** ***; Guillo Christelle; Ferrance Jerome P; Landers James P. Microfluidic-based DNA purification in a two-stage, dual-phase microchip containing a reverse phase and a photo-polymerized monolith. Nucleic Acids Research, (***) In review.
*** *** ***; Hartberger Travis, Ferrance Jerome P; Landers James P. Multiplex DNA Purification for Large Volume Blood
Samples on a Microfluidic Device. In preparation.
*** *** ***; Evans Natalie, Ferrance Jerome P; Landers James P. Microfluidic Lab-on-chip for Clinic: Minimal Residual
Disease (MRD)Detection. In preparation.
*** *** ***; Ferrance Jerome P; Landers James P. On-line Coupling the Immobilized Trypsin Monolith for Protein Digestion with Monolithic Reverse Phase Separation/ESI-MS within a Microfluidic Device. In preparation.
PATENTS
*** Hu, Xianming; Li, Guihua; ***, ***; Li, Jun; Hu, Quanyuan. Resolution of ibuprofen by two-component chiral reagents.
Faming Zhuanli Shenqing Gongkai Shuomingshu, ***a (***).
*** ***, ***, Ferrance, Jerome P.; Landers, James P. Grafted Photo-Polymerized Monolithic Column, International Patent
Application(***), No. PCT/US***/***
PROFESSIONAL AFFILIATIONS

Member, American Chemical Society Washington, D.C
Member, American Biophysical Society Bethesda, MD scientist