CURRICULUM VITAE ALAN ANTON MARCHIONDO, M.S., Ph.D. HOME ADDRESS 10308 N. Dallas Ave Kansas City, MO 64154-1884 Phone/Fax: 816-880-0588 Cell Phone: 573-808-0203 BUSINESS ADDRESS IVX Animal Health, Inc. (formerly Phoenix Scientific, Inc.) 3915 S. 49th St. Terrace P.O. Box 8039 (64508) St. Joseph, MO 64503-4711 816-676-6151 800-759-3664, Fax: 816-676-6874 E-mail: alan_marchiondo@ivax.com EDUCATION Ph.D., Zoology, 1982 (Parasitology) Brigham Young University, Provo, UT. Dissertation Title: Comparative Biological Aspects of Taeniidae with Special Reference to Echinococcus: Chemotherapy, Speciation, Elemental Analysis, and Ultrastructural Observations. M.S., Biology, 1974 (Parasitology) University of New Mexico, Albuquerque, NM. Thesis Title: Toxoplasma Antibodies in Wild and Domiciled Animals from Arizona, Colorado, Montana, New Mexico, and the Philippines. B.S., Biology, 1971 University of New Mexico, Albuquerque, NM. PROFESSIONAL BACKGROUND IVX ANIMAL HEALTH, INC., ST. JOSEPH, MO Director of Clinical Development 3/07-Present. Direct and coordinate the design and conduct of clinical project development activities of veterinary products. Directs and coordinates scheduling of clinical studies with Regulatory Affairs and Product Chemistry for submission of data packaged to the appropriate regulatory agency. Supervises technical staff assigned to projects. IVX ANIMAL HEALTH, INC. (Formerly PHOENIX SCIENTIFIC, INC.), ST. JOSEPH, MO Manager, Clinical Projects, Pharmaceutical Development 4/02-3/07. Plan and conduct clinical pharmaceutical product development and target animal safety studies leading to ANADA’s, NADA’s and EPA registrations. Coordinate clinical studies with regulatory affairs, product chemistry, quality assurance and contract research organizations. Curriculum Vitae Alan A. Marchiondo, Ph.D. 2 MERIAL LIMITED, MISSOURI RESEARCH CENTER, FULTON, MO Research Scientist 1/98-3/02. Conduct pharmaceutical and biological evaluations (basic, pre-clinical or clinical) and target animal safety trials for developmental research and registration of animal health products in regional and global markets. Supervise maintenance and propagation of ecto- and endoparasite colonies/cultures for in vitro screening and in vivo efficacy trials. RHONE MERIEUX, INC., RHONE POULENC AG CO., RESEARCH TRIANGLE PARK, NC Manager of Biology/Project Manager, Parasiticide Evaluation 11/95-12/97. Directly responsible for management of the Rhone Merieux parasiticide discovery research program at Rhone Poulenc Ag including primary (conventional and high throughput), secondary and tertiary screening and pre-clinical development for pet, companion and food producing animals. FERMENTA ANIMAL HEALTH COMPANY, KANSAS CITY, MO Director, Pet Insecticides & Anthelmintics, 1/92-10/95. Directly responsibility for domestic and international new product research, commercial development and regulatory approval of small animal/household insecticides and endoparasiticide products for pet, companion and food producing animals. Manager, Parasiticide Development, 2/89-12/91. Directly responsible for commercial development of ectoparasiticide products containing insect growth regulators (IGRs) for premise and on-animal uses and endoparasiticide products for pets, swine and cattle. Product Development Parasitologist 5/87-1/89. Responsible for new product research and commercial development of potential parasiticides for domestic and international animal health markets. SDS BIOTECH CORP./RICERCA. INC., PAINESVILLE, OH Senior Research Parasitologist, 8/84-4/87. Direct responsibilities included supervision of primary screening, secondary evaluations and new product research of potential parasiticides as well as provided research support of existing parasiticide products. UNIVERSITY OF NOTRE DAME, DEPARTMENT OF BIOLOGY, NOTRE DAME, IN NIH Postdoctoral Fellow, 10/82-7/84. Conducted basic research in helminth physiology and developmental biology utilizing axenic culture procedures to study nutritional, metabolic and physicochemical factors involved in growth and differentiation of nematodes and cestodes. Curriculum Vitae Alan A. Marchiondo, Ph.D. 3 BRIGHAM YOUNG UNIVERSITY, DEPARTMENT OF ZOOLOGY, PROVO, UT Research Associate, 4/80-9/82. Conducted basic and applied research on the physiology, developmental biology and chemotherapy of unilocular and alveolar hydatid disease. UNIVERSITY OF TEXAS MEDICAL BRANCH, DEPARTMENT OF PATHOLOGY, GALVESTON, TX Research Associate, 7/78 7/79. Performed diagnostic electron microscopy for various pathology services and conducted finestructural research of parasitic organisms. UNIVERSITY OF NEW MEXICO, DEPARTMENT OF BIOLOGY, ALBUQUERQUE, NM Director, Electron Microscopy Facility, 7/75-6/78 Supervised the operation of the electron microscopy facility, taught a graduate course in EM techniques and conducted research on the ultrastructural aspects of parasitic protozoa and helminths. MILITARY SERVICE United States Coast Guard Reserve, Honorable Discharge, 1967-1973, Hospital Corpsman, E-5. MOST SIGNIFICANT ACCOMPLISHMENTS Basic Research Patent Declaration Under 37 CFR 1.132. Synergistic activity of Fipronil and (S)-Methoprene. U.S. Patent 45313-2339. Insecticidal combination to control mammal fleas, in particular fleas on cats and dogs. Issued 1 Aug 2000. Identified and demonstrated the in vitro and in vivo flea ovicidal synergy of Fipronil + (S)-Methoprene combinations and products. As Discovery Biologist at Rhone Poulenc Ag , I identified a new chemical class of anthelmintic, a systemic flea and tick adulticide for pets, and a new arylpyrazole compound highly active against ectoparasites of food producing animals, 1996. Successfully incorporated in vitro parasiticide targets into the high throughput screening program at Rhone Poulenc Ag, 1996. Established in vivo parasiticide screening programs at various research facilities throughout the U.S.A. and in Brazil, 1995-1996. Identified and described the biological and morphological modes of action of the IGR, Fenoxycarb (Tenocide), against the life cycle stages of the cat flea, 1990. Curriculum Vitae Alan A. Marchiondo, Ph.D. 4 Systemic flea ovicidal efficacy of Fenoxycarb demonstrated via oral and percutaneous routes of administration, Fermenta Animal Health, 1990. Discovered the selective toxicity of diazinon against pyrethroid-resistant horn flies. This discovery lead to the commercial development of the first insecticidal cattle ear tag (Terminator, Fermenta Animal Health Co.) and subsequent diazinon ear tags (Patriot, Fermenta Animal Health Co.) effective against pyrethroid-resistant horn flies, 1985. Developed a method of preparing permanent light microscopy slides of coccidian oocysts. No significant changes in the characteristic morphology of the oocysts for over a period of 10 years, 1978-1988. Product Development Supplemental NADA 200-342 Pyrantel Pamoate Equine Paste for removal and control of mature infections of Anoplocephala perfoliata, removal and control of large strongyles, small strongyles, pinworms (Oxyuris equi) and large roundworms (Parascaris equorum) in horses and ponies. FDA/CVM approved 20 April 2005. Clinical evaluation coordinator for efficacy and pharmacokinetics section of EPA registration of Frontline Plus for Dogs and Cats, 1999-2000. Commercially developed and registered eight domestic and three international insecticide products for flea and tick control, Fermenta Animal Health. Development experience with several small and large animal generic anthelmintics (tablets, granules, suspensions, pour-ons and injectables) and in vivo bloodlevel and clinical end-point bioequivalency evaluations, 1989-1994. Canine pour-on (5 ml) containing fenoxycarb or pyriproxyfen for control of emerging adult fleas from shed flea eggs for up to five months. Pyriproxyfen product possesses inherent adulticidal flea activity of >80% for five months. The extended adulticidal label claim of the pyriproxyfen pour-on illustrated the direct application of an in vitro research finding (Meola et al., 1993 Proc. First Intern. Conf. on Insect Pests in the Urban Environ., Cambridge, pp.221-228) to an end-use product, 1995. Canine spot-on (1 ml) containing fenoxycarb or pyriproxyfen for 28-35 days control of adult fleas and ticks plus 99% flea ovicidal activity for 90 days. Ovicidal activity against the Brown dog tick and the American dog tick was demonstrated as well, 1995. Novel IGR pet collar development, Fermenta Animal Health, 1995. Americare Lawn Spray for flea and tick control, EPA Reg. No. 56493-94, 1994. Americare Flea & Tick Shampoo Plus for dogs and cats, EPA Reg. No. 56493-91, 1994. Expanded federal label of Rabon Oral Larvicide by establishing suspendability and manufacturing guidelines for use in bovine liquid feed supplements, 1993. Curriculum Vitae Alan A. Marchiondo, Ph.D. Americare Rabon Flea & Tick Collar for dogs (EPA Reg. No. 56493-89) and cats (EPA Reg. No. 56493-90), 1993. Americare (EctoGard) Invert Aerosol House & Carpet Spray for control of flea infestations in households, kennels and outdoor areas around homes, EPA Reg. No. 56493-86, 1992. Americare (EctoGard) Pet Spray for ovicidal and adulticidal control of fleas on pets, EPA Reg. No. 56493-85, 1991. This product was the only fenoxycarb pet spray approved for both dogs and cats. Ciba, Lambert-Kay and S.C. Johnson subregistered the product for its safety and efficacy on cats. EctoGard Fogger for ovicidal and adulticidal flea and cockroach control, EPA Reg. Nos. 56493-79, 83, 84, 1989. EctoGard House & Carpet Spray for ovicidal and adulticidal flea and cockroach control, EPA Reg. Nos. 56493-78, 81, 82, 1989. Developed strategic deworming program for swine for Atgard C, 1990. Transdermal diethylcarbamazine product developed for monthly prophylaxis of canine dirofilariasis, 1990. COLLEGIATE TEACHING EXPERIENCE: Graduate Teaching Assistantship, Medical and Veterinary Parasitology, Department of Zoology, Brigham Young University, 1979-1980. Instructor, Biological Techniques in Electron Microscopy, Department of Biology, University of New Mexico, 1975-1978. Graduate Teaching Assistantship, General Microbiology, Department of Biology, University of New Mexico, 1973-1974. RESEARCH GRANTS Co-Investigator, NIH AI-10588. Epidemiology of echinococcosis, 1980-1982. Principal Investigator, BYU Graduate Internship Fund. Chemotherapy of experimental alveolar hydatid disease, 1980-1981. Co-Investigator, Brown-Hazen Fund. Antibodies to Toxoplasma gondii in wild and domestic animals, 1973-1974. 5 Curriculum Vitae Alan A. Marchiondo, Ph.D. 6 AWARDS AND HONORS Award of Excellence, Companion Animal Project Team, Merial Ltd., 1999. Nikon International Small World Light Photomicroscopy Competition. Seventeenth Place. Unembryonated eggs of the swine whipworm, Trichuris suis, 400X, 1994. International Sales Achievement Award, Fermenta Animal Health Co., 1991. Chairman's Award. Development of Fenoxycarb product line, Fermenta Animal Health., 1989. EctoGard™ Task Force Award, Fermenta Animal Health., 1989. Polysciences, Inc. Photography Contest. Second Place. Color Photomicroscopy Category. Human squamous epithelial cells and bacteria stained with acridine orange, photographed by fluorescence microscopy, 100X, 1986. Polaroid International Instant Photomicrography Competition. Eighth Prize. Electron Microscopy Category. Rostellar hooks of Taenia krabbei, SEM, 280X, 1986. Datus M. Hammond Award, Best Student Demonstration. Rocky Mountain Conference of Parasitologists, Laramie, WY, 1980. Phi Kappa Phi (Honors Student), Brigham Young University, 1980. PROFESSIONAL MEMBERSHIP American Association for the Advancement of Science, 1984-Present. American Society of Parasitologists, 1973-Present; Business Advisory Committee, 1989-1992; Outreach Committee, 1990-1994; Industrial Liaison Committee, 1992-1997, 2002-2005, Chairman: 1994-1996, Organized the First Industrial Liaison Symposium: Alliances for Knowledge & Technology, Joint Meeting of ASP & AAVP, Pittsburgh, PA, 1995. American Association of Veterinary Parasitologists, 1984-Present; Outreach/Research Committee, 1989-1992; Chairman, Outreach/Research Committee, 1991-1992; Designed, coordinated minting and directed sale of a collector's silver proof coin commemorating the 100th anniversary of the discovery of the life cycle of Babesia bigemina, causative agent of Texas cattle fever, 1993; Chairman, Ad Hoc Committee, Central Veterinary Conference, Organized 2nd and 3rd AAVP Symposia, 1994-1995; Organized First AAVP Symposium at AAHA National Meeting, 1996; Nominating Committee 1998-2001, Chairman 1999-2000; Finance Committee 2003-2004; Designed silver proof coin commemorating 50th Meeting Anniversary of AAVP; AAVP Secretary/Treasurer 2004-Present. Animal Drug Alliance (formerly the Generic Pharmaceutical Industry Association's (GPIA) Animal Drug Alliance), member 1990-1995; Science Committee, 1990 1991. Curriculum Vitae Alan A. Marchiondo, Ph.D. Sigma Xi Research Society, University of Notre Dame, 1983-Present. World Association for the Advancement of Veterinary Parasitology (WAAVP), 1984-Present. RESEARCH-RELATED SERVICE Editorial Board Member - Veterinary Parasitology, 1988-Present. Peer Reviewer: Journal of Parasitology, 1986-Present. Parasitology Research, 1990-Present. Journal of Agriculture, Ecosystems & Environment, l994-Present. Journal of Aquatic Animal Health, 1996-Present. Journal of Vector Ecology, 2001-Present Preventive Veterinary Medicine, 2006 Arab Science & Technology Foundation’s Iraq Research and Development Initiative, 2006 SPECIALIZED TRAINING Fundamentals of Effective Project Management, Rockhurst University, Continuing Education Center, Inc., Columbia, MO, 2001. Molecular Biochemistry and Physiology of Helminth Neuromuscular Systems/Molecular Basis of Drug Design and Resistance, City University, London, U.K., 1996. FDA Workshop on Compliance Requirements for Animal Drug Manufacturers: General Principles of Process Validation, Kansas City, MO, 1991.Good Manufacturing Practices, Kansas City, MO, 1990. Molecular Paradigms for Eradicating Helminth Parasites. UCLA Symposia on Molecular & Cellular Biology, Steamboat Springs, CO, 1987. Setting the Climate for Performance Improvement. Case Western Reserve University, Management Development Program, Cleveland, OH, 1985. Problem Solving and Decision Making. SDS Biotech Corporation, Painesville, OH, 1985. Physiological Chemistry of Animal Parasites. University of Notre Dame, Notre Dame, IN, 1984. The Johns Jacob Abel Symposium on Drug Development. The Johns Hopkins University School of Medicine, Baltimore, MD, 1983. Introduction to Radiation, Biological Effects of Ionizing Radiation, Instrumentation and Principles of Radiation Protection. University of Notre Dame, Notre Dame, IN, 1983. 7 Curriculum Vitae Alan A. Marchiondo, Ph.D. SCIENTIFIC PUBLICATIONS Sogandares-Bernal, F., A.A. Marchiondo, D.W. Duszynski, and J.K. Ward, 1975. Prevalence of Toxoplasma antibodies in range vs dairy cattle from the Bitterroot Valley of Montana. J. Parasitol. 61:965-966. Marchiondo, A.A., D.W. Duszynski, and G.O. Maupin, 1976. Prevalence of antibodies to Toxoplasma gondii in wild and domestic animals of New Mexico, Arizona, and Colorado. J. Wildl. Dis. 12:226-232. Speer, C.A., A.A. Marchiondo, D.W. Duszynski, and S.K. File, 1976. Ultrastructure of the sporocyst wall during excystation of Isospora endocallimici. J. Parasitol. 62:984-987. Duszynski, D.W., M.A. Altenbach, A.A. Marchiondo, and C.A. Speer, 1977. Eimeria crotalviridis sp. n. from prairie rattlesnakes, Crotalus viridis viridis, in New Mexico with data on excystation of sporozoites and ultrastructure of the oocyst wall. J. Protozool. 24:359-361. Marchiondo, A.A. and D.W. Duszynski, 1978. Permanent light microscopy slides of Eimeria nieschulzi oocysts. J. Parasitol. 64:163-164. Marchiondo, A.A. and T.W. Sawyer, 1978. Scanning electron microscopy of the head region of Physaloptera felidis Ackert, 1936. Proc. Helm. Soc. Wash. 45:258-260. Marchiondo, A.A. and T.S. Foxx, 1978. Scanning electron microscopy of the solenidion on genu I of Cheyletiella yasguri and C. parasitivorax. J. Parasitol. 64:925-927. Marchiondo, A.A., D.W. Duszynski, and C.A Speer, 1978. Fine structure of the oocyst wall of Eimeria nieschulzi. J. Protozool. 25:434-437. Mayberry, L.F., A.A. Marchiondo, J.E. Ubelaker, and D. Kazic, 1979. Rhabdospora thelohani Laguesse, 1985 (Apicomplexa): New host and geographic records with taxonomic considerations. J. Protozool. 26:168-178. Speer, C.A., A.A. Marchiondo, B. Mueller, and D.W. Duszynski, 1979. Scanning and transmission electron microscopy of the oocyst wall of Isospora lacazei. Z. Parasitenkd. 59:219 225. Marchiondo, A.A., J.H. Smith, and S.K. File, 1980. Naturally occurring leprosy-like disease of wild armadillos: ultrastructure of lepromatous lesions. J. Reticuloendothel. Soc. 27:311-325. Box, E.D., A.A. Marchiondo, D.W. Duszynski, and C.P. Davis, 1980. Ultrastructure of Sarcocystis sporocysts from passerine birds and opossums: comments on classification of the genus Isospora. J. Parasitol. 68:68-74. 8 Curriculum Vitae Alan A. Marchiondo, Ph.D. Marchiondo, A.A., 1981. Scanning electron microscopy of the egg of Cheyletiella yasguri Smiley (Acari: Cheyletiellidae) with a description of the egg burster. Int. J. Insect Morphol. & Embryol. 10:167-171. Duszynski, D.W., C.A. Speer, B. Chobotar, and A.A. Marchiondo, 1981. Fine structure of the oocyst wall and excystation of Eimeria procyonis from the American Raccoon (Procyon lotor). Z. Parasitenkd. 65:131-136. Becker, S.N., J.Y. Wong, A.A. Marchiondo, and C.P. Davis, 1981. Scanning electron microscopy of alcohol-fixed cytopathology specimens. Acta Cytol. 25:578-585. Crellin, J.R., A.A. Marchiondo, and F.L. Anderson, 1981. Comparison of suitability of dogs and cats as hosts of Echinococcus multilocularis. Am. J. Vet. Res. 42:1980-1981. Conder, G.A., A.A. Marchiondo, and F.L. Andersen, 1981. Effect of praziquantel on adult Echinococcus granulosus in vitro: scanning electron microscopy observations. Z. Parasitenkd. 66:191-199. Conder, G.A., A.A. Marchiondo, J.F. Williams, and F.L. Andersen, 1983. Freeze-etch characterization of the teguments of three metacestodes: Echinococcus granulosus, Taenia crassiceps, and Taenia taeniaeformis. J. Parasitol. 69:539-548. Marchiondo, A.A. and F.L. Andersen, 1983. Fine structure and freeze-etch study of the protoscolex tegument of Echinococcus multilocularis (Cestoda). J. Parasitol. 69:709-718. Conder, G.A., A.A. Marchiondo, J.F. Williams, and F.L. Andersen, 1983. Ultrastructural characterization of serum-induced changes in the tegument of Taenia taeniaeformis. J. Parasitol. 69:838-845. Marchiondo, A.A. and F.L. Andersen, 1984. Light microscopy and scanning electron microscopy of the in vitro evagination process of Echinococcus multilocularis protoscolices. Int. J. Parasitol. 14:151-157. Marchiondo, A.A., G.A. Conder, and F.L. Andersen, 1985. Freeze-etch study of the germinal layer in the cyst of Echinococcus multilocularis (Cestoda). Trans. Am. Micros. Soc. 104:79-85. Marchiondo, A.A. and F.L. Andersen, 1985. In vivo efficacy and ultrastructural effects of mitomycin C against experimental alveolar hydatid disease. J. Helminthol. 59:29 38. Marchiondo, A.A., J.F. Karpowitz, and G.A. Conder, 1986. Parasites of the bobcat (Lynx rufus pallescens) in Central and Southern Utah. Proc. Helm. Soc. Wash. 53:113 116. Marchiondo, A.A. and S.J. Upton, 1987. Eimeria albigulae and E. ladronensis: New host records from the bushy-tailed woodrat, Neotoma cinerea, from Utah. J. Parasitol. 73:421-422. 9 Curriculum Vitae Alan A. Marchiondo, Ph.D. 10 Marchiondo, A.A. and J. Szanto, 1987. Efficacy of dichlorvos, fenbendazole, and ivermectin in swine with induced intestinal nematode infections. Am. J. Vet. Res. 48:1233-1235. Marchiondo, A.A., P.P. Weinstein, and J.F. Mueller, 1987. In vitro and in vivo enzymatic dissolution of the plerocercoid body of Spirometra mansonoides (Cestoidea). Int. J. Parasitol. 17:1313-1320. Sheppard, D.C. and A.A. Marchiondo, 1987. Toxicity of diazinon to pyrethroid resistant and susceptible horn flies, Haematobia irritans (L.): Laboratory studies and field trials. J. Agric. Entomol. 4:262-270. Kennedy, T.J., Bruer, D.J., A.A. Marchiondo, and J.A. Williams, 1988. Prevalence of swine parasites in major hog producing areas of the United States. Agri-Practice. 9:25-32. Marchiondo, A.A. and D.W. Duszynski, 1988. On the status of Eimeria nieschulzi oocysts embedded in resin eleven years ago: A permanent method for preserving coccidian oocysts. J. Parasitol. 74:737-739. Upton, S.J., A.A. Marchiondo, and R.N. Williams, 1988. New species of Isospora (Apicomplexa: Eimeriidae) from passeriform birds of Hawaii. Syst. Parasitol. 12:81-85. Marchiondo, A A., P.P. Weinstein, and J.F. Mueller, 1989. Significance of the distribution of 57 Co-vitamin B12 in Spirometra mansonoides (Cestoidea) during growth and differentiation in mammalian intermediate and definitive hosts. Int. J. Parasitol. 19:119-124. Marchiondo, A.A., J.L. Riner, D.E. Sonenshine, K.F. Rowe and J.H. Slusser, 1990, Ovicidal and larvicidal modes of action of fenoxycarb against the cat flea (Siphonaptera: Pulicidae). J. Med. Entomol. 27: 913-921. Marchiondo, A.A., R. Ming, F.L. Andersen, J.H. Slusser and G.A. Conder, 1994. Enhanced larval cyst growth of Echinococcus multilocularis in praziquantel-treated jirds, Meriones unguiculatus. Am. J. Trop. Med. Hyg. 50:120-127. Marchiondo, A.A., S. M. Meola,. K.G. Palma, J.H. Slusser and R.W. Meola, 1999. Chorion formation and ultrastructure of the egg of the cat flea (Siphonaptera, Pulicidae). J. Med. Entomol. 36 (2): 149-157. Smith K.E., R. Wall, J.J. Howard, L. Strong, A.A. Marchiondo and Ph. Jeannin, 2000. In vitro insecticidal effects of fipronil and -cyfluthrin on larvae of the blowfly, Lucilia sericata. Vet. Parasitol. 88 (3,4):261-268. Marchiondo, A.A., T.N. TerHune and R.L. Herrick, 2005. Target animal safety and tolerance study of pyrantel pamoate (19.13% w/w pyrantel base) paste orally administered to horses. Vet. Therapeutics 6 (4):311-324. Curriculum Vitae Alan A. Marchiondo, Ph.D. 11 Marchiondo, A.A., C.R. Reinemeyer, 2006. Equine Cestodiasis: Biology and treatment of Anoplocephala perfoliata. Jpn. J. Vet. Parasitol. 4 (2):1-8. Marchiondo, A.A., G.W. White, L.L. Smith, C.R. Reinemeyer, J.J. Dascanio, E.G. Johnson and J.L. Shugart, 2006. Clinical field efficacy and safety of pyrantel pamoate paste (19.13% w/w pyrantel base) against Anoplocephala spp. in naturally infected horses. Vet. Parasitol. 137 (12):94-102. Reinemeyer, C.R., D.E. Hutchens, W.P. Eckblad, A.A. Marchiondo and J.I. Shugart, 2006. Doseconfirmation studies of the cestocidal activity of pyrantel pamoate paste in horses. Vet. Parasitol. 138: 234-239. Marchiondo, A.A., P.A. Holdsworth, P. Green, B.L. Blagburn, D.E. Jacobs, 2007. World Association for the Advancement of Veterinary Parasitology (W.A.A.V.P.) guidelines for evaluating the efficacy of parasiticides for the treatment, prevention and control of flea and tick infestations on dogs and cats. Vet. Parasitol. 145: 332-344. NON-REFEREED JOURNAL PUBLICATIONS Szanto, J. and A.A. Marchiondo, 1986. Whipworm infection in swine. Animal Health & Nutrition. 41:18-22. Marchiondo, A.A., 1987. Biology, economic effect and control of the horn fly. Animal Health & Nutrition. 42:6-10. Reprinted in Norden News, 1987, 62:10-16. Reprinted in CHIKUSAN-NO-KENKYU {Animal Husbandry) in Japanese, 1994, 48(5):69-73. Marchiondo, A.A. and J.L. Riner, 1988. Integrated control program for the horn fly. Large Animal Vet. 43:22-24. Marchiondo, A.A., J.L. Riner and H.R Sinclair, 1989. Mode of action of insect growth regulators against fleas. Proceedings of EXPO 1989, Veterinary Learning Systems, pp. 25-26. Marchiondo, A.A., 1993. Safe and effective flea control for cats. Veterinary Technician 14(4):235-245. Marchiondo, A.A. and G.A. Conder, 1994. A correlative LM/SEM method. USA Microscopy and Analysis, July, Issue 7, p. 11. INVITED PRESENTATIONS Marchiondo, A.A., 1988. An introduction to the unique biological systems of the tapeworm, Spirometra mansonoides. Department of Biological Sciences, The University of Texas at El Paso, TX. Curriculum Vitae Alan A. Marchiondo, Ph.D. 12 Marchiondo, A.A., J.L. Riner and H.R. Sinclair, 1989. Mode of action of insect growth regulators against fleas. Veterinary Learning Systems EXPO '89 Series, Dallas, TX and Chicago, IL. Marchiondo, A.A., 1990. Discovery and development of antiparasitic agents against arthropods. Symposium on Discovery and Development of Anti-Parasitic Drugs. 65th Annual Meeting of the American Society of Parasitologists, Michigan State University, East Lansing, MI. Marchiondo, A.A., 2004. Industrial Collaborative Research Processes. Industrial Relations Symposium: Industry, Academia and Government. 2004 Joint Meeting of the American Association of Veterinary Parasitologists (49th Meeting) and the American Society of Parasitologists (79th Meeting), Philadelphia, PA. PAPERS PRESENTED AT SCIENTIFIC MEETINGS Mayberry, L.F., A.A. Marchiondo, and E.R. Noble, 1977. Rhabdospora thelohani: an Apicomplexan parasite or a rodlett cell. 52nd Annual Meeting of the American Society of Parasitologists, Las Vegas, NV. Ruocco, J.J., A.A. Marchiondo, L.L. Barton, and J.V. Scaletti, 1978. Electron microscopy of Desulfovibrio gigas with identification of inclusion bodies containing polymeric-betahydroxybutyrate. 79th Annual Meeting of the American Society of Microbiologists, Las Vegas, NV. Boor, P.J., T.J. Nelson, A.A. Marchiondo, and P. Chieco, 1979. Morphological localization of monoamine oxidase (MAO) in normal and fibrotic rat heart. 52nd Scientific Session of the American Heart Association, Anaheim, CA. Marchiondo, A.A. and F.L. Andersen, 1980. The ultrastructural anatomy of the protoscolex and cyst wall of Echinococcus multilocularis. 55th Annual Meeting of the American Society of Parasitologists, Berkeley, CA. Andersen, F.L., A.A. Marchiondo, and G.A. Conder, 1981. Efficacy of praziquantel against Echinococcus spp. 26th Annual Meeting of the American Association of Veterinary Parasitologists, St. Louis, MO. Marchiondo, A.A. and F.L. Andersen, 1981. Light microscopy and scanning electron microscopy of the evagination process of the protoscolices of Echinococcus multilocularis. 56th Annual Meeting of the American Society of Parasitologists, Montreal, Canada. Conder, G.A., Marchiondo, A.A., J.F. Williams and F.L. Andersen, 1981. Freeze-etch characterization of the tegument of three larval cestodes. 56th Annual Meeting of the American Society of Parasitologists, Montreal, Canada. Curriculum Vitae Alan A. Marchiondo, Ph.D. 13 Bristol, J.R., A.A. Marchiondo, L.F. Mayberry, and A.G. Canaris, 1981. Comparative ultrastructure of larval and adult Brachylaime microti (Trematoda:Brachylaimidae) teguments. 56th Annual Meeting of the American Society of Parasitologists, Montreal, Canada. Marchiondo, A.A., P.P. Weinstein, and J.F. Mueller, 1983. Vitamin B12 distribution in the regenerated sparganum of Spirometra mansonoides. 58th Annual Meeting of the American Society of Parasitologists, San Antonio, TX. Marchiondo, A.A., 1986. Comparative efficacy and economic performance of Atgard C and Ivomec against Ascaris suum, Trichuris suis, and Oesophagostomum dentatum in experimentally-infected swine. 104th Annual Meeting of the Iowa Veterinary Medical Association, Des Moines, IA and the American Association of Swine Practioners, Minneapolis, MN. Marchiondo, A.A. and D.C. Sheppard, 1987. Toxicity of diazinon to pyrethroid-resistant horn flies: Laboratory studies and field trials. 31st Annual Livestock Insect Workers Conference, Beltsville, MD. Bandoni, S.M., D.W. Duszynski, and A.A. Marchiondo, 1987. Are names of coccidian species valid under the Zoological Code of Nomenclature? 62nd Annual Meeting of the American Society of Parasitologists, Lincoln, NE. Marchiondo, A.A., J.L. Riner, D.E. Sonenshine, K.F. Rowe and J.H. Slusser, 1989. Ovicidal efficacy and ultrastructural mode of action of fenoxycarb on flea eggs. 34th Annual Meeting of the American Association of Veterinary Parasitologists, Orlando, FL. Marchiondo, A.A., J.L. Riner, D.E. Sonenshine, K.F. Rowe and J.H. Slusser, 1989. Modes of action of fenoxycarb against developmental stages of the cat flea, Ctenocephalides felis. 64th Annual Meeting of the American Society of Parasitologist, Vancouver, BC. Marchiondo, A.A. and G.A. Conder, 1990. Philatelic Salute to Parasitology. 65th Annual Meeting of the American Society of Parasitologists, East Lansing, MI. Marchiondo, A.A., S. Ackers, S.W. Fogt, D.L. Heimbichner and R. Young, 1992, 1993. Efficacy and safety of fenoxycarb pet spray for control of Ctenocephalides felis infestations on dogs and cats. 37th Annual Meeting of the American Association of Veterinary Parasitologists, Boston, MA, and Second International Symposium on Ectoparasites of Pets, Lexington, KY. Ming, R, F.L. Anderson, A.A. Marchiondo, G.A. Conder and J.H. Slusser, 1992. Enhanced growth of alveolar hydatid cysts in praziquantel-treated jirds (Meroines unguiculatus). 37th Annual Meeting of the American Association of Veterinary Parasitologists, Boston, MA. Curriculum Vitae Alan A. Marchiondo, Ph.D. 14 Marchiondo, A.A., S.M. Meola, R.W. Meola, K.G. Palma and J.H. Slusser, 1995. Ultrastructure of the egg of the cat flea. Third International Symposium on Ectoparasites of Pets, ColIege Station, TX. Marchiondo, A.A., S.W. Fogt, D.L. Heimbichner and S.L. Stroh, 1995. Efficacy of azadirachtin and pyriproxyfen against developing stages of the cat flea, Ctenocephalides felis. Joint Meeting of the American Society of Parasitologists & the American Association of Veterinary Parasitologists, Pittsburgh, PA. Marchiondo, A.A., S.M. Meola, K.G. Palma, R.W. Meola and J.H. Slusser, 1996. Development and ultrastructure of the cat flea eggshell. Joint Meeting of the American Society of Parasitologists & the Society of Protozoologists, Tucson, AZ. Gant, D.B., A.B. Chalmers, M.A. Wolff, H.B. Hoffman and D.F. Bushey, 1996. Mode of action of Fipronil. Presented by A.A. Marchiondo. 41st Annual Meeting of the American Association of Veterinary Parasitologists, Louisville, KY. Dryden, M.W., A.A. Marchiondo, S. Ackers and S.W. Fogt, 1996. Residual control of Ctenocephalides felis development by single site applications of insect growth Regulators on infested cats. 41st Annual Meeting of the American Association of Veterinary Parasitologists, Louisville, KY. McCall, J.W., S.L. Stroh, A.A. Marchiondo and T.L. McTier, 1997. Canine heartworm prophylaxis by high oral dosages or transdermal administration of Diethylcarbamazine. 42nd Annual Meeting of the American Association of Veterinary Parasitologists, Reno, NV. Marchiondo, A.A., S.E. Green, R.E. Plue, D.H. Wallacae, R.A. Barrick and P. Jeannin, 1999. Comparative speed of kill of Frontline Top-Spot, Frontline Spray and Advantage against adult cat fleas (Ctenocephalides felis) on dogs. 5th International Symposium on Ectoparasites of Pets, Fort Collins, CO. Marchiondo, A.A., J.A. Feltner, R.E. Plue, D.H. Wallace, M.N. Romano and W.R. Langholff, 1999. Method validation for louse transfer of Bovicola bovis and Linognathus vituli from donor to principal cattle. 44th Annual Meeting of the American Association of Veterinary Parasitologists, New Orleans, LA. Marchiondo, A.A., C. Robertson-Plouch, R.A. Barrick, J. Guerrero, and P. Jeannin, 1999. Comparative speed of kill of Frontline Top-Spot, Frontline Spray and Advantage against adult cat fleas (Ctenocephalides felis) on dogs. 5th European Small Animal Veterinary Congress: FECAVA, Lyon, France. Curriculum Vitae Alan A. Marchiondo, Ph.D. 15 Marchiondo, A.A., S.E. Green, D.H. Wallace, R.A. Barrick and P.C. Jeannin, 2000. Efficacy of a Fipronil/(S)-Methoprene combination spot-on product against the cat flea, Ctenocephalides felis, on cats. 4th World Congress of Veterinary Dermatology, San Francisco, CA. Jeannin, P.C., D.R. Young and A.A. Marchiondo, 2000. Efficacy of a Fipronil/(S)-Methoprene combination spot-on product against the cat flea, Ctenocephalides felis, on dogs. 4th World Congress of Veterinary Dermatology, San Francisco, CA. Marchiondo, A.A., S.E. Green, D.H. Wallace and P.C. Jeannin, 2001. Efficacy of Frontline Plus against the cat flea (Ctenocephalides felis), the brown dog tick (Rhipicephalus sanguineus), and the American dog tick (Dermacentor variablilis) on dogs. 6th International Symposium on Ectoparasites of Pets, Westport, Co. Mayo, Ireland. Marchiondo, A.A., S.E. Green, R.E. Plue and D.H. Wallace, 2001. Synergistic ovicidal activity of Fipronil and (S)-Methoprene against the cat flea, Ctenocephalides felis. 6th International Symposium on Ectoparasites of Pets, Westport, Co. Mayo, Ireland. Marchiondo A.A., S.E. Green, R.E. Plue and D.H. Wallace, 2001. Inhibitory effect of Fipronil or (S)-Methoprene on development of different ages of cat flea, Ctenocephalides felis, eggs. 6th International Symposium on Ectoparasites of Pets, Westport, Co. Mayo, Ireland. Meola, S.M. and A.A. Marchiondo, 2001. Chorion ultrastructure of the egg of the stable fly, Stomoxys calcitrans (L.) (Diptera: Muscidae). 6th International Symposium on Ectoparasites of Pets, Westport, Co. Mayo, Ireland. Plue, R.E., R. Everett, J. Cunningham, R. Barrick and P. Jeannin, 2001. An efficacy comparison of Frontline Plus, Advantage and Revolution for the control of Ctenocephalides felis on dogs shampooed weekly. Presented by A.A. Marchiondo. 6th International Symposium on Ectoparasites of Pets, Westport, Co. Mayo, Ireland. Marchiondo, A.A., D.R. Young and P.C. Jeannin, 2001. Efficacy of a Fipronil/(S)-Methoprene combination spot-on product against the cat flea, Ctenocephalides felis, on dogs. 46th Annual Meeting of Veterinary Parasitologists, Boston, MA. Marchiondo, A.A., S.E. Green, D.H. Wallace, R.A. Barrick and P.C. Jeannin, 2001. Efficacy of a Fipronil/(S)-Methoprene combination spot-on product against the cat flea, Ctenocephalides felis, on cats. 46th Annual Meeting of Veterinary Parasitologists, Boston, MA. Marchiondo, A.A., J.A. Feltner, R.E. Plue, D.H. Wallace, M.N. Romano and W.K. Langholff, 2001. Method validation for louse transfer of Bovicola bovis and Linognathus vituli from donor to principal cattle. 46th Annual Meeting of Veterinary Parasitologists, Boston, MA. Curriculum Vitae Alan A. Marchiondo, Ph.D. 16 Marchiondo, A.A., J.E. Holste, B.N. Kunkle, J.A. Feltner, R.E. Plue, K.E. Sterner, W.K. Langholff and D.H. Wallace, 2001. Method validation for louse transfer of Bovicola bovis and Linognathus vituli from donor to principal cattle and two studies to demonstrate the persistent effect of IVOMEC Topical in preventing the establishment of lice. 45th Annual Livestock Insect Workers’ Conference, Cody, WY. Marchiondo, A.A., 2004. Industrial Collaborative Research Processes. Industrial Relations Symposium: Industry, Academia and Government. 2004 Joint Meeting of the American Association of Veterinary Parasitologists (49th Meeting) and the American Society of Parasitologists (79th Meeting), Philadelphia, PA. Geary, T.G., D.S. Lindsay, T.J. Kennedy and A.A. Marchiondo, 2005. Industrial Symposium: Do they ever get it right? What industry is funding. 80th Annual Meeting of the American Society of Parasitologists, Mobile, AL. Reinemeyer, C.R., D.E. Hutchens, W.P. Eckblad, A.A. Marchiondo and J.I. Shugart, 2005. Doseconfirmation studies of the cestocidal activity of pyrantel pamoate paste in horses. 50th Annual Meeting of the American Association of Veterinary Parasitologists, Minneapolis, MN; 20th International Conference of the World Association for the Advancement of Veterinary Parasitology, Christchurch, New Zealand. Marchiondo, A.A., G.W. White, L.L. Smith, C.R. Reinemeyer, J.J. Dascanio, E.G. Johnson and J.I. Shugart, 2005. Pyrantel pamoate paste (19.13% w/w pyrantel base): clinical field efficacy and safety against Anoplocephala spp. in naturally-infected horses. 50th Annual Meeting of the American Association of Veterinary Parasitologists, Minneapolis, MN; 20th International Conference of the World Association for the Advancement of Veterinary Parasitology, Christchurch, New Zealand. Reinemeyer, C.R., A.A. Marchiondo and J.I. Shugart., 2006. Macrocyclic lactone-resistant Oxyuris equi: Antecdote or emerging problem? 51st Annual Meeting of the American Association of Veterinary Parasitologists, Honolulu, HI. Reinemeyer, C.R. and A.A. Marchiondo, 2007. Efficacy of pyrantel pamoate in horses against a macrocyclic lactone-resistant isolate of Parascaris equorum. 52nd Annual Meeting of the American Association of Veterinary Parasitologists, Washington, DC. Alan A. Marchiondo Signature Revised 22 September 2007 AAMcv05L.doc 22 September 2007 Date