Infection Prevention and Control Annual Report 2012 Joanne Flanagan, Infection Prevention and Control Nurse Specialist (CNS) PAGE TITLE PAGE Introduction 1 Infection prevention and control structures 2 Committee membership 2&3 The Infection prevention and control Team Infection prevention and control policies, procedures and guidelines 3 Education and Training 3 Hand hygiene World Health Organisation 'Five Moments of Hand hygiene' 3 3&4 4 Sleeves Up' Campaign 4&5 Hand hygiene compliance 5&6 Data Collection 5 Blackrock Clinic Targets 6 Hand hygiene education attendance 6 Audits and Actions taken 7&8 Clostridium difficile Infection rates Staphlococcus aureus and Meticillin Resistant Staphlococcus aureus 8&9 10 & 11 Vancomycin Resistant Enterococci rate 13 Other Organisms requiring Isolation 14 Extended Spectrum Beta- Lactamase producers Carbepenem- Resistant Enterbacteriaceae 14 & 15 15 Surgical Site Infection rate for Cardiac Surgery 15, 16 & 17 Surgical Site Infection rate for Orthopaedic Surgery 17, 18 & 19 Outbreak of Infection 19 Project Development 19 Environmental Hygiene 20 Vaccination Programme 20 & 21 Antimicrobial Therapy 21, 22, 23, 24, 25 & 26 INTRODUCTION The term “Healthcare Associated Infection” (HCAI) encompasses any infection caused by an infectious agent acquired as a consequence of a person’s treatment or is acquired by a healthcare worker in the course of their duties. The Health Information and Quality Authority (HIQA) is an independent Authority which was established under the Health Act 2007 to drive continuous improvement in Ireland’s health services. In May 2009 HIQA launched The National Standards for the Prevention and Control of Healthcare Associated Infections. These twelve standards are a key component in maximising patient safety and improving quality of care. Blackrock Clinic also is accredited by Joint Commissioner International (JCI). The Infection Prevention and Control (IP&C) Annual Report provides an opportunity to highlight the infection prevention and control activities that have been put in place in the hospital throughout 2012. The prevention and control of infection is valued and given high priority in Blackrock Clinic. A programme of activities to embrace national initiatives and to reduce infection rates has been developed and implemented. The activities which contribute to infection prevention and control are carried out by all departments within the hospital. Infection prevention and control is the responsibility of all healthcare workers and is incorporated into everyday practice. The objective is to engage staff at all levels in order to maintain a culture that supports infection prevention and control practices across the entire hospital. The IP&C programme has a multi-faceted role in preventing the development and transmission of disease, which includes surveillance of healthcare associated infections, resistant organisms and the prevention of infection and control of existing infection. 1 INFECTION PREVENTION AND CONTROL STRUCTURES The hospital’s Chief Executive is ultimately responsible for the prevention and control of infection in Blackrock Clinic however infection prevention and control is the responsibility of all staff. The Infection Prevention and Control Committee (IPCC) is chaired by the Matron (Director of Nursing) and the CEO sits on the Committee. The Committee is responsible for providing an infection control strategy in Blackrock Clinic. The IP&C committee analysed surveillance figures, infection control audits, outbreak reports and also ratified all updated and new infection prevention and control policies, procedures and guidelines throughout 2012. MEMBERSHIP OF THE INFECTION PREVENTION AND CONTROL COMMITTEE 2012 NAME TITLE Bryan Harty Chief Executive Carmel Mangan Matron Dr. Anne Gilleece Consultant Microbiologist Dr. Lynda Fenelon Consultant Microbiologist Dr. Kirsten Schaffer Consultant Microbiologist Joanne Flanagan Infection Prevention and Control CNS Dr. George Duffy Medical Consultant Mr. Colin Riordan Surgical Consultant Dr. Harry Beauchamp Medical Consultant Dr Ailin Roger Registrar Brian McEntee Pharmacist Miriam McKeown ICU Manager Edel Costigan Quality Manager Daryl Simpson Assistant Director of Nursing Rosemary Leonard Theatre Manager Agnes O’Gorman Day Unit Manager Joan Giltrap Accommodation Manager Maria Hayes Cardiothoracic Clinical Nurse Specialist Mary O’Gorman Theatre Clinical Nurse Specialist 2 Susan Healy General Surgical Clinical Nurse Specialist Lisa Cadden Oncology Clinical Nurse Specialist Claire Hogan Orthopaedic Clinical Nurse Specialist Michael McGowan Facilities and Project Manager THE INFECTION PREVENTION AND CONTROL TEAM (IP&CT) The IP&CT includes the IP&C Nurse specialist and Consultant Microbiologist. The IP&CT continues to provide operational direction and advice to clinical and non-clinical staff within the Hospital. The IP&CT is supported by the microbiology laboratory. INFECTION PREVENTION AND CONTROL POLICIES, PROCEDURES AND GUIDELINES The IP&C policies, procedures, guidelines and programmes are available on Q-Pulse. The IP&CT has a programme for revision of these as per hospital policy. EDUCATION AND TRAINING Education is a key component in reducing avoidable infection. All new staff starting in the hospital receive hand hygiene education as part of their orientation programme. Nursing staff receive a more extensive orientation where the infection control nurse specialist signs each nurse off on their competencies. In 2012, 95 new staff attended the orientation programme. Existing clinical staff receive regular education sessions which focus on specific topics, relating to infection prevention and control. This may be on a new product or updated changes on an existing policy. Other education sessions are delivered in addition and include informal ward based sessions, telephone advice, information leaflets and posters. Alongside the Infection Prevention and Control Nurse, the CNS in each specialty has assisted in staff education in relation to infection control throughout 2012. HAND HYGIENE Hand hygiene includes washing your hands with soap and water and cleaning your hands with an alcohol based hand rub. In 2011, Blackrock Clinic started measuring hand hygiene using the same audit tool as all other hospitals in Ireland. In 2012 Blackrock Clinic commenced submitting our audit results to the Health Protection Surveillance Centre (HPSC) hand hygiene database. This allows our compliance rate to be benchmarked against other 3 hospitals in Ireland. All healthcare provider groups including physicians, contracted employees and students are included in the audits. WORLD HEALTH ORGANISATION (WHO) ‘FIVE MOMENTS FOR HAND HYGIENE’ The newly developed Five Moments for Hand Hygiene has emerged from the WHO Guidelines on Hand Hygiene in Health Care to add value to any hand hygiene improvement strategy. Quite simply, it defines the key moments for hand hygiene with a view to overcoming misleading language and complicated descriptions. It presents a unified vision and promotes a strong sense of ownership. The Five Moments not only aligns with the evidence regarding the spread of HCAI but it is interwoven with the natural workflow of care and is designed to be easy to learn, logical and applicable in a wide range of settings. The illustration overleaf shows the Five moments of hand hygiene. OUR ‘SLEEVES UP’ CAMPAIGN In March 2012 we introduced ‘Sleeves Up’ campaign in Blackrock Clinic. Initially ‘Hand Hygiene’ and ‘Sleeves Up’ were audited separately. This allowed for a focus to be placed on the physical attire of healthcare workers. 4 WHAT IS THE PURPOSE OF THIS INDICATOR AND WHY IS IT IMPORTANT? This hand hygiene indicator measures healthcare worker compliance in Blackrock Clinic and benchmarks against other hospitals in Ireland. Hand hygiene is universally accepted as the single most important method of infection prevention and control. Wrists must be bare to wash your entire hand and wrist correctly. HAND HYGIENE COMPLIANCE, PERIOD 4 2012 The overall compliance for period 4, 2012 in Blackrock Clinic was 89.6%. This includes a breakdown of disciplines and the Five Moments of hand hygiene. Table 1 Staff compliance with hand hygiene Table 2 Compliance with each moment of hand hygiene DATA COLLECTION The IP&C Nurse Specialist inputs the data to the HPSC database on a quarterly basis. We started to benchmark our data with the HPSC in Period 3 2012. There has been an improvement with our hand hygiene compliance from period 3 to period 4 (see graph overleaf). 5 Hand hygiene compliance in Blackrock Clinic 2012 Overall complaince for period 3 = 88.1% Overall compliance for period 4 = 89.6% 100.00% 96.70% 94.10% Hand hygiene compliance 95.00% 90.90% 90.00% 89.80% 90% 90% 88.90% 88.50% 88% 86.70% 86.70% 86.70% 86.70% Period 3 Period 4 85.00% 83.30% 80.00% 75.00% WSU ACU PFU FNU ICU DU ED Period 3 86.70% 96.70% 86.70% 90% 86.70% 83.30% 86.70% Period 4 88.90% 94.10% 89.80% 88% 88.50% 90% 90.90% Table 3 Hand hygiene compliance for period 3 and period 4 2012 BLACKROCK CLINIC TARGET FOR 2012 Our aim was to achieve 85% compliance in hand hygiene audits in 2012. HAND HYGIENE EDUCATION ATTENDANCE FOR 2012 Hand hygiene education is mandatory education and our aim was to achieve a 100% attendance in 2012. See graph overleaf for results. 6 Hand Hygiene education attendance 2012 in Blackrock Clinic Overall Attendence in 2012 is 76% 120% 100% 100% 100% 100% 100%100% 100%100% 94% 91% 86% 80% 86% 75% 70% 60% 69% 66% 64% 61% 67% 63% 60% 52% Hand hygiene attendance 47% 39% 40% 22% 20% ward closed IT E UA D LI TY RA P DI HY S OL IO A G DM LE IN NA LL A CA RD LA B IO PH LO AR G Y M AC Y Q EY AN E G EN RA I O G IN DI O EE L R AC I NG CO CA M TE M O T 5t RIN h FL G O O R T O IC U DU G AC U W SU FN U PF U FN U 0% Table 4 Hand hygiene education attendance AUDITS Quarterly hand hygiene audits (210 hand hygiene opportunities) were carried out and results submitted to the HPSC. The IP&C Nurse Specialist carried out the audits. Our aim is to get more auditors trained by the HPSC to assist in these audits in 2013. WHAT ACTIONS HAVE BEEN TAKEN OVER THE LAST YEAR? A number of actions have been taken over the last year including: • To Benchmark our hand hygiene results with the Health Protection Surveillance Centre (HPSC). • A new campaign called ‘Sleeves up’ was launched in March 2012. • We increased communication with the physician group. There were numerous leaflets, letters and audit results and presentation given to the physicians to remind them about the importance of hand hygiene compliance. • Hand hygiene education took place as a part of orientation programme for all new staff. • Night supervisors and CNS in theatre were trained to carry out hand hygiene education. This helped increase education attendance for off peak staff. 7 • One of our aims was to introduce a hand hygiene E learning tool. The committee decided to wait until the HSE tool is completed. This will compliment the audit tool we currently use from the HPSC. • Dedicated hand hygiene sinks are available in all patient rooms and clinical areas. AN INTRODUCTION TO CLOSTRIDIUM DIFFICILE INFECTIONS (CDI) RATES Clostridium difficile is a bacterium that can cause infections of the gastrointestinal system. Clostridium difficile infection (CDI) happens when antibiotics kill the good bacteria in the gut and allow Clostridium difficile to grow and produce toxins that can damage the bowel. CDI can cause infections ranging from diarrhoea (common) to rare but serious complications that require prolonged treatment with antibiotics and sometimes surgery. In extreme cases CDI can result in death. The elderly and immunocompromised are particularly at risk for these complications NATIONAL ENHANCED SURVEILLANCE OF CLOSTRIDIUM DIFFICILE • In Q3 2012 there were 400 cases of Clostridium difficile infection (CDI) from 43 acute hospitals reported to the enhanced surveillance system. This gives a national CDI rate of 2.5 cases per 10,000 bed days used. This is less than that reported last quarter 4 (2.7 cases) and for the same period in 2011 (2.7 cases). • Overall there is a small decrease in the incidence of CDI in 2012. (Median CDI rate = 1.8 cases) compared to 2011 (median CDI rate = 2.2 cases). The significance of this decline is difficult to determine due to changes in C. difficile testing methodologies across laboratories during this time period. The table overleaf shows the national quarterly trend of CDI since 2009. 8 Table 5 National Clostridium difficile rates in Irish hospitals HOW DOES BLACKROCK CLINIC COMPARE TO OTHER PRIVATE HOSPITALS? We commenced enhanced surveillance with the HPSC in Quarter 4, 2011. In Blackrock Clinic there was a decrease in CDI from quarter 2 to quarter 3, 2012. The table below highlights the CDI infection rate in private hospitals since 2009. We have been included in this surveillance since 2011. CDI cases per 10,000 BDUs 3.5 3 2.5 2 1.5 1 0.5 0 Q3 Q4 2009 Q1 Q2 Q3 Q4 2010 Private rate Q1 Q2 Q3 Q4 2011 Q1 Q2 Q3 2012 Your Rate Table 6 Clostridium difficile rates in private hospitals in Ireland 9 2009 2010 2011 2012 Q3 Q4 Q1 Q2 Q3 Q4 Q1 Q2 Q3 Q4 Q1 Q2 Q3 National Rate 2.8 3.3 3.0 2.6 2.8 2.9 3.6 3.0 2.7 2.9 2.6 2.7 2.5 Private rate 0 0.8 0.5 0.5 1.9 1.6 1 1.6 0.8 1 0.5 0.7 1.2 N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.8 0.9 1.8 1 Blackrock Clinic rate Table 7 the national CDI rates, private CDI rates. This also refers to Blackrock Clinic rate. STAPHYLOCOCCUS AUREUS (S AUREUS)/ METICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS (MRSA) BACTERAEMIA Meticillin-resistant Staphylococcus Aureus (MRSA) is a strain of staphylococcus aureus bacterium that is resistant to a number of antibiotics. S aureus normally lives on human skin and in the noses of about 25% of the general population (a process called colonization). However S aureus can cause skin infections such as boils and abscesses and more serious diseases such as bloodstream and respiratory infections. Infections that occur in people who have been in hospital or who have had other healthcare encounters are referred to as healthcare-associated MRSA (HA-MRSA). Risk factors for HAMRSA infection includes invasive procedures such as surgery, insertion of indwelling catheters or intravenous tubing. Another type of MRSA infection is associated with acquiring the organism in the community (CA-MRSA). Factors that have been associated with the spread of CA-MRSA include close skin-to-skin contact and openings in the skins such as abrasions. 10 Table 1. Total number of S aureus No. Estimated Total S. bloodstream infections, numbers of Laboratories % Pop/n aureus meticillin-susceptible and meticillin- MSSA MRSA %MRSA Coverage resistant S. aureus, and proportion (%) MRSA reported to the HPSC as part of the European Antimicrobial Resistance Surveillance Network (EARS-Net) over the period 2004-2012. Year 2004 41 96 1,323 770 553 41.8% 2005 42 98 1,424 832 592 41.6% 2006 42 98 1,412 820 592 41.9% 2007 44 98 1,393 857 536 38.5% 2008 43 98 1,303 864 439 33.7% 2009 43 100 1,309 954 355 27.1% 2010 40 100 1,251 946 305 24.4% 2011 41 100 1,095 832 263 24.0% 2012* 41 100 1,060 818 242 22.8% Table 8 the total number of episodes of Staphylococcus aureus bloodstream infections, numbers of meticillin-susceptible and meticillin-resistant S. aureus, and proportion (%) MRSA reported to the Health Protection Surveillance Centre (HPSC) as part of the European Antimicrobial Resistance Surveillance Network (EARS-Net) over the period 2004-2012. SOME FACTS ABOUT MRSA ON A NATIONAL LEVEL In quarter 4 of 2012, 23.9% of S aureus were MRSA (68 of 285). MRSA decreased from 41.9% in 2006 to 22.8% in 2012, which is provisionally the lowest annual proportion since surveillance began in 1999. Between the peak in 2005/2006 and 2012, the numbers of MRSA decreased by 59%. 11 Table 9 The map illustrates the distribution of MRSA in EARS-Net (previously EARSS) countries in 2011 (Map downloaded from ECDC’s TESSy database on 22/10/2012) MRSA per ward in Blackrock Clinic in 2012 This is measured per bed days used 0.25% 0.20% 0.20% 0.15% 0.13% MRSA on Adm 0.10% 0.10% Hospital Acquired MRSA 0.10% 0.06% 0.05% 0.05% 0.04% 0.05% 0.02% 0% 0.00% ICU WSU ACU FNU PFU Table 10 The MRSA rate per bed days used (BDU) in Blackrock Clinic in 2012 12 VANCOMYCIN RESISTANT ENTEROCOCCI (VRE) INCIDENCE RATE Vancomycin Resistant Enterococci (VRE) is a type of Enterococci bacteria that is resistant to the antibiotic Vancomycin. Enterococci are bacteria found in the gastrointestinal tract (bowel) in most healthy people. They can also be found on the skin and in wounds. This is normal and is called colonization. In some people, especially those who are very ill, Enterococci can cause an infection. In quarter 4 of 2012, 46.5% of E. faecium in Ireland (53 of 114) were VRE. The HPSC reported that VRE increased from 33.4% in 2007 to 46.8% in 2012, which is provisionally the highest annual proportion reported to date. There was no hospital-acquired VRE in 2012. All the VRE diagnosed in Blackrock were diagnosed on admission screening swabs process. The number of patients that were diagnosed with VRE on admission to Blackrock clinic in 2012 3.5 3 3 2.5 2 2 Diagnosed on admission 1.5 1 1 0.5 0 0 0 0 0 0 0 0 0 Jun Jul Aug Sep Oct Nov Dec 0 Jan Feb Mar Apr May Table 11 The number of patients diagnosed with VRE in Blackrock Clinic in 2012 The laboratory surveillance identified other organisms that required isolation in 2012. There were no trends noticed amongst these organisms. 13 Patients with other organisms that required isolation in 2012 4.5 4 4 3.5 3 3 Dengue fever,Herpes meningitis, TB, Flu 2.5 2 On Admission HA 2 2 Campylobacter/ TB 1.5 Scabies Shingles Lyme 1 1 1 Campylobacter 0.5 Salmonella Meningitis(HA) 1 Shingles 1 Campylobacter Legionella 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec 0 Jan Table 12 The other organisms that required isolation in 2012. EXTENDED SPECTRUM BETA-LACTAMASE (ESBL)-PRODUCERS ESBLs are bacteria that live in the bowel and that cannot be treated by commonly used antibiotics. For most patients, ESBLs lives harmlessly in the bowel and do not cause infection. However, sometimes ESBLs can cause infection in patients. Patients who have already taken a lot of antibiotics are more at risk of developing ESBLs. The reason for this is that the bacteria are more exposed to antibiotics, and are therefore more likely to develop ‘resistance’ to that antibiotic, so that antibiotic no longer works. In Europe, invasive E. coli isolates are reported as part of the European Antimicrobial Resistance Surveillance System (EARSS, http://www.rivm.nl/earss/). In Ireland, the proportion of E. coli isolates that were tested for presence of ESBL, and tested positive, increased from 1.3% in 2004 (11/861) to 2.7% in 2005 (30/1132 tested) [1,2]. The 2004 EARSS report comments that the proportion of E. coli resistant to third generation cephalosporins increased from 1.5% 2001 to 2.9% (P<0.0001) in 2004, probably due to increased dissemination of ESBL producers. The increase was consistent across the countries surveyed by EARSS. 14 The number of patients diagnosed with ESBL in Blackrock Clinic in 2012 4.5 4 4 3.5 3 3 3 Number of pts 3 2.5 On Admission 2 Healthcare associated 2 Emergency dept 2 1.5 1 1 1 1 1 1 0.5 0 0 0 0 0 0 Jan Feb 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Mar Apr May Jun Jul Aug Sep Oct Nov Dec Table 13 The number of patients that were diagnosed with ESBL in Blackrock clinic in 2012. CARBAPENEM-RESISTANT ENTEROBACTERIACEAE (CRE) Carbapenem antibiotics have been invaluable for the treatment of infections caused by multi resistant Gram-negative organisms over the last decades. The increasing rates of gramnegative isolates expressing carbapenem-hydrolyzing enzymes are posing a significant threat for the usage of carbapenem antibiotics. Detection of unidentified carriers is essential for successful control. Active surveillance was introduced in 2011. The Committee’s recommendation is to screen patients who have been inpatients for more than 48h in healthcare facilities reporting outbreaks with CRE as per HPSC website. There were no cases of CRE detected in Blackrock Clinic in 2012. SURGICAL SITE INFECTION (SSI) SURVEILLANCE CARDIAC SURGERY SSI SURVEILLANCE The overall cardiac surgery SSI infection rates have reduced since 2009. Many interventions have been put in place from the entire cardiac team to achieve this reduction. The SSI’s are broken down into categories i.e. superficial, deep and organ space SSI. There is a weekly cardiac surgery team meeting on William Stokes Unit. At these meetings each patient is discussed. Also on the agenda are new interventions introduced, such as the introduction of silicone dressings (to avoid blistering caused by adhesives), sternal binders as a prophylactic 15 measure in reducing sternal dehiscence (mainly for at-risk patients) and education of all staff about the importance of aseptic technique. Deep surgical site infection (SSI) rate 2012 is 0% for Cardiac surgery 100% 90% 80% 70% SSI as a % 60% 50% Deep SSI 40% 30% 20% 10% 0% 0% 0% 0% 0% 0% 0% 0% 0% 0% 0% 0% Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec 0% Table 14 the deep wound infection rates in 2012. Cardiac surgical site infection (SSI) rate 2012 in Blackrock Clinic Overall SSI Rate = 2.9% Superficial SSI Rate = 2.7 (Benchmark 8.5%) Sternal SSI Rate = 2.2% (Benchmark 5.6%) Donor SSI Rate = 0.4% (Benchmark 2.2%) Overall SSI Rate in 2011= 3.9% 12.00% 1 Suture knot 10.00% 10.00% SSI as a % 8.00% 6.00% 6.00% Superficial SSI rate 4.00% 3.00% 2.40% 2.20% 2.70% 3.00% 2.50% 2% 2.00% 1 Donor 1 Donor 0.00% 0.00% 0.00% 0.00% Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec Table 15 the Superficial SSI rate in 2012 16 Surgical Site Infection (SSI) rates for Cardiac Surgery from 2009- 2012 in Blackrock Clinic 7.00% 5.90% 6.00% SSI rate 5.00% 4.70% 3.90% 4.00% SSI rate 2.90% 3.00% 2.00% 1.00% 0.00% *2009 *2010 *2011 *2012 Table 16 The SSI trend since 2009 ORTHOPAEDIC SURGERY SSI SURVEILLANCE The orthopaedic surgery SSI’s are broken down into categories i.e. superficial, deep and organ space SSI. There is a monthly Orthopaedic surgery team meeting on Abraham Colles Unit. At these meetings each patient is discussed and wound infections are categorised. Overall Hip Superfical Surgical site infection (SSI) rate 2012 is 0.3% Benchmark is 2.09% (2011 SSI rate was 1.67%) 4.00% 1.2 3.80% 3.50% 1 1 3.00% 2.00% 0.6 1.50% No. pts with SSI SSI rate as a % 0.8 2.50% SSI rate No. pts with SSI 0.4 1.00% 0.2 0.50% 0.00% 0.00% 0 Jan 0.00% 0 Feb 0.00% 0 Mar 0.00% 0 Apr 0.00% 0 May 0.00% 0 Jun 0.00% 0 Jul 0.00% 0 Aug 0.00% 0 Sep 0% Oct 0 Nov 0.00% 0 Dec 0 17 Overall Knee Surgical site infections (SSI) rate 2012 is 0% Benchmark is 0.9% (2011 SSI rate was 0.4%) 1 90.00% 0.9 80.00% 0.8 70.00% 0.7 60.00% 0.6 50.00% 0.5 40.00% 0.4 30.00% 0.3 20.00% 0.2 10.00% 0.00% No. pts with SSI SSI as a % 100.00% SSI rate No. pts with SSI 0.1 0.00% 0 Jan 0.00% 0 Feb 0.00% 0 Mar 0.00% 0 Apr 0.00% 0 May 0.00% 0 Jun 0.00% 0 Jul 0.00% 0 Aug 0.00% 0 Sep 0.00% 0 Oct 0% 0 Nov 0.00% 0 Dec 0 Table 17 the infection rates for hip and knee surgery in 2012 Hip Surgical Site Infection rate from 2009- 2012 3.00% 2.60% 2.50% 2.00% 1.67% 1.50% 1.50% SSI Rate 1.00% 0.50% 0.30% 0.00% *2009 *2010 *2011 *2012 18 Knee Surgical Site Infection Rate from 2009- 2012 1.40% 1.20% 1.20% 1.00% 0.80% SSI Rate 0.60% 0.40% 0.40% 0.40% 0.20% 0.00% 0.00% *2009 *2010 *2011 *2012 Table 18 The SSI trends since from 2009 to 2012 in Hip and Knee surgery OUTBREAK OF INFECTION There were no reported outbreaks of infection in 2012 in Blackrock Clinic. PROJECT DEVELOPMENT Blackrock Clinic commenced a major development project in 2008. During 2012 the IC&P Nurse Specialist and Consultant Microbiologist remained actively involved throughout the ongoing construction outside and within the hospital, both in advising on the provision and design of facilities within a variety of projects. The IP&C Nurse Specialist closely monitored activity during each phase of the project. Risk assessments of works were carried out and are available on Q Pulse. Dust checks were carried out by the accommodation supervisors. Any increase in dust levels was immediately reported to the construction manager and work was stopped until the problem was investigated and resolved. In these cases, air sampling was carried out using fungal media. HEPA filtration was implemented in high risk patient areas throughout the hospital as a preventative measure. There were no cases of hospital acquired invasive aspergillosis or Legionella in 2012. 19 ENVIRONMENTAL HYGIENE The IP&C Nurse Specialist continues to attend the Hygiene Committee that meets on a weekly basis within clinical areas. Clinical managers or staff in charge are invited to attend and discuss various hygiene topics within their area. A visual inspection of the area is also carried out and findings are reported to each manager. All clinical managers receive minutes of these meetings. There is a patient information leaflet supplied in all bedrooms to provide patients with information on how their room is cleaned. An audit tool was introduced in 2012. This facilitated a team approach to audits carried out in clinical areas. AUDIT RESULTS AVERAGE 2012 97.00 95.94 96.00 95.36 94.94 95.00 94.61 94.81 94.00 93.18 93.03 92.71 93.00 92.62 92.60 91.96 91.50 92.00 91.00 94.72 94.54 90.11 90.02 90.23 90.00 89.00 88.00 ol o r M gy 5t ed h Fl i oo cin e rT G he ro at un re dT he at re P hy si o C Fr SS on tC D or rid or N 5t h uc l ea O nc og y y io l ar d C U ol og IC ad i R D ng io A ov ec or R 4t h Fl o E er y or Fl o or r Fl o 3r d Fl oo d 2n 1s tF lo o r 87.00 Table 19 The average hygiene audit score in 2012 VACCINATION PROGRAMME Blackrock Clinic encourages all staff to avail of the influenza vaccination annually, to reduce the risk of transmission to vulnerable patients. A Hepatitis B vaccination programme is provided for all clinical and accommodation staff prior to employment. Personal protective clothing is supplied to all clinical areas to reduce the risk of exposure to body fluid. Staff also have access to an occupational health facility where they can seek advice and treatment, where necessary. 20 ANTIMICROBIAL THERAPY INTRODUCTION In May 2012, 50 acute Irish hospitals (42 public and 8 private) participated in the voluntary European Centre for Disease Prevention and Control (ECDC) point prevalence survey (PPS) of hospital acquired infections (HAI) and antimicrobial use (AMU). The survey was coordinated in Ireland by the Health Protection Surveillance Centre (HPSC), the national centre for the surveillance of infections in Ireland. The breakdown of participating hospitals by type included: 15 primary/general, 10 secondary/regional, 6 tertiary, 11 specialist public, 1 specialist private and 7 other private hospitals. Although the Blackrock Clinic did not participate in the PPS the Pharmacy Department conducted a similar point prevalence audit on the 1st of November which has been completed for the previous three years. These results provide us with a snapshot of number of patients who were prescribed antimicrobials in the Clinic on that day. We aim to conduct a PPS for 2013 this coming autumn. This year we intend to collect data regarding compliance with the Antimicrobial Guidelines and involvement of Microbiology, where necessary, in choosing appropriate treatment. ANTIMICROBIAL USE PREVALENCE Percentage of Inpatients on Antimicrobials 45.00% 40.00% percentage 35.00% 30.00% 25.00% On Abc 20.00% Treatment Prophylaxis 15.00% 10.00% 5.00% 0.00% 2012 N=108 2011 N=110 2010 N =81 2009 N=83 On Abc 38.90% 36.4% 31% 39% Treatment 29.60% 26.4% 18.5% 30% 9.30% 10.0% 13% 9% Prophylaxis number of patients Table 20 NPPS 2012 antimicrobial use prevalence = 34% 1 21 Top Antimicrobials Prescribed - Treatment and Prophylaxis Coamoxiclav Ciprofloxacin Flucloxacillin Cefuroxime Rifampicin 2012 Penicillin 2011 Clarithromycin 2010 Trimethoprim 2009 Piperacillin Metronidazole Clindamycin Fluconazole 0.0% 5.0% 10.0% 15.0% 20.0% 25.0% 30.0% 35.0% Table 21 The top antimicrobials prescribed were Co-amoxicillin (15%), Ciprofloxacin (14%), Flucloxacillin (12%) and Cefuroxime (10%), followed by Rifampicin, Penicillin, Clarithromycin and Piperacillin/Tazobactam (all approximately 5%). Top Antimicrobials Prescribed 2012 - Treatment Only 18.00% 16.00% 14.00% 12.00% 10.00% 8.00% 6.00% 4.00% 2.00% C C ip ro f lo oa xac in m Fl oxic uc l l o av xa R cill i i C fam n la p rit i hr cin om y Pe cin n Pi icil pe lin r C acil ef l ur in C oxi m lin da e m Fl uc yci n M on a et z ro ol e ni da D z ap o to le m Le vo ycin flo x Li m aci n e Tr cyc im l et i ne ho Va p nc rim om yc in 0.00% 22 Indication 35.00% 30.00% 25.00% 20.00% 2012 2011 15.00% 10.00% 5.00% BJ EN T UN Pr op D h U TI G I BA C SI R S RE SP G U M O TH UT I pr Pn op eu h M Pr ED op pr h C op T h SB O J B pr G op Y h EN T ND SS T 0.00% BAC Bacteraemia BJ Septic arthritis, osteomyelitis ENT Ear, nose, throat, larynx GI Gastrointestinal GUM Prostitis, epididymo-orchitis ND Not documented, no indication given OBGY Obstetric, gynaecological OTH Other Pneu Pneumonia Proph CT Cardio-thoracic prophylaxis Proph ENT Ear, nose, throat prophylaxis Proph MED Medical Prophylaxis Proph SBJ Orthopaedic/Plastic prophylaxis Proph UTI Urological Prophylaxis RESP Respiratory (non-pneumonia) SIRS Systemic with no clear anatomic site SST Cellulites, wound, deep soft tissue UND Undefined site and no systemic inflammation UTI Urinary (lower and upper) Table 22 Top Antimicrobials used at the time of the point prevalence 23 There was a documented indication for the antimicrobial prescription in 79% (NPPS 83% 1). The indication for prescription was for treatment of infection in 71% of cases (NPPS 78% 1), surgical antimicrobial prophylaxis in 15% of cases (NPPS 11% 1) and medical prophylaxis in 6% of cases (NPPS 8% 1). The most common infection sites for which antimicrobials were prescribed on the day of the study included; skin/soft tissue (29%), urinary tract infections (10%), Pneumonia (8.6%). These were followed by medical, cardio-thoracic and orthopaedic prophylaxis (all approximately 5%). Percentage of Patients on Parenteral Antimicrobials 70.00% 60.00% 50.00% 40.00% 30.00% 20.00% 10.00% 0.00% 2012 2011 2010 2009 Table 23 NPPS 2012: 63% on parenterals 1 The parenteral (i.e., intravenous) route accounted for most prescribed antimicrobials (63%) in the NPPS 1. In contrast less than half of patients were on IV antimicrobials on the day of our study, although this figure was higher the previous year. 24 Allergy Status Completed yes 2% no 98% Percentage of Penicillin Allergic Patients allergic 8.60% not allergic 91.40% Reason for Treatment in Notes no yes 31% 69% 25 Duration of Treatment Recorded yes no 32.70% 67.30% Culture Pre-Therapy no yes 31% 69% REFERENCE LIST 1. Health Protection Surveillance Centre, Point Prevalence Survey Hospital Acquired Infections & Antimicrobial Use in European Acute Care Hospitals: May 2012 – Republic of Ireland National Report: November 2012. Foley, M et al. Last accessed 22nd April 2013. Available at: http://www.hpsc.ie 26 We would like to thank all the staff in Blackrock Clinic for their help in reducing infection throughout 2012. We would also like to thank the Infection Prevention and Control Committee for their support and advice throughout 2012. 27