Supplementary Table 3. Genes of Study Gene Symbol CXCR4 Name of Gene Chemokine receptor-4 Function/Role Reference uPAR Urokinase plasminogen activator receptor cMET Cell motility factor receptor AMFR Autocrine motility factor receptor 11-13 LOX Lysyl oxidase 14, 15 Fas Tumour necrosis factor Receptor VEGFC Vascular endothelial growth factor-C 1-3 4-7 Intra/Extravasation Anti-Apoptotic 8-10 16, 17 18-21 Angiogenic factors IL8 Interleukin -8 22-24 Hdm2 Transformed 3T3 double minute 2 25, 26 OPN Osteopontin CA-9 Carbonic anhyrdase IX Survival/Growth factors 27-30 Biomarker for hypoxia 31-33 Supplementary References 1. Shim H, Lau SK, Devi S, et al. Lower expression of CXCR4 in lymph node metastases than in primary breast cancers: potential regulation by liganddependent degradation and HIF-1alpha. Biochem Biophys Res Commun 2006;346:252-258. 2. Darash-Yahana M, Pikarsky E, Abramovitch R, et al. Role of high expression levels of CXCR4 in tumor growth, vascularization, and metastasis. 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