BIOGRAPHICAL SKETCH
Provide the following information for the Senior/key personnel and other significant contributors in the order
listed on Form Page 2.
Follow this format for each person. DO NOT EXCEED FOUR PAGES.
NAME
Chi-Wei Lu
eRA COMMONS USER NAME (credential, e.g.,
agency login)
luchiwei
POSITION TITLE
Assistant Professor
EDUCATION/TRAINING (Begin with baccalaureate or other initial professional education, such as nursing,
include postdoctoral training and residency training if applicable.)
INSTITUTION AND LOCATION
DEGREE
(if
applicable)
MM/YY
FIELD OF STUDY
UMDNJ/Rutgers University
Ph.D.
05/2003
Biochemistry
Harvard Medical School
Postdoctoral
04/2007
Stem Cell Biology
B. Positions and Honors
2007-2008
Assistant Scientist, McKnight Brain Institute, University of Florida, (Nov 2007-August 2008)
2008-2011
Director of Human Embryonic Stem Cell Laboratory, Robert -Wood Johnson Medical School,
Assistant Professor, Department of Obstetrics, Gynecology and Reproductive Science, and
University of Medicine and Dentistry of New Jersey (October 2008-2011).
2009
Ellison Medical Foundation New Scholar, 2009
2011-present Member, Child Health Institute of New Jersey and Assistant Professor, Department of Obstetrics,
Gynecology and Reproductive Science (April 2011-present)
C. Selected Peer-reviewed Publications
1. Yasunari Seita, Su Jin, Jianlin Zhuan, Bradley Phelan, Arnold Rabson, Nathan Treff and Chi-Wei Lu. CDX2
establishes a proliferative trophoblastic stem cell fate from differentiating human embryonic stem cells.
Submitted April 2014.
2. Chi-Wei Lu, Yasunari Seita, Nathan Treff and Monica Roth (2013) Ethnic disparity in stem cell availability
and research. Book chapter In Ethnic differences in fertility and assisted reproduction. Springer, in press
3. Lan Yi, Chi-Wei Lu, Wen-Wei Hu and Arnold Levine, Multiple roles of p53 related pathways in somatic
cell reprogramming and stem cell differentiation. (2012) Cancer Research 72(21) 5625-45 PMID: 22964580
4. Dai-tze Wu, Yasunari Seita, Xia Zhang, Chi-Wei Lu and Monica Roth, Ph.D. Antibody-directed lentiviral
gene transduction for live-cell monitoring and selection of human iPS and hES cells. (2012) Plos One,
7(4):e34778. PMID: 22536330
5. Chen LY, Yabuuchi A, Eminli S, Takeuchi A, Lu CW, Hochelinger K and Daley GQ (2009) Cross-regulation
of Nanog and Cdx2. Cell Research, 19(9), 1052-61. PMID: 19564890
6. Viswanathan SR, Mermel CH, Lu J, Lu CW, Golub TR and Daley GQ (2009) MicroRNA expression during
trophectoderm specification. PLoS One, 4(7) e6143. PMID: 9582159
7. Chi-Wei Lu, Lingyi Chen, Akiko Yabuuchi, Srinivas Viswanathan, Kitai Kim and George Q. Daley (2008)
Ras-Mitogen Activated Protein Kinase Signaling Promotes Trophectoderm Lineage Establishment.
Nature Genetics Jul; 40(7)921-6. PMID: 1853675
8. Kyba M, Perlingeiro RC, Hoover RR, Lu CW, Pierce J, Daley GQ. (2003) Enhanced hematopoietic
differentiation embryonic stem cells conditionally expressing Stat5. PNAS 100 Suppl. 1 11904-11910.
8. Lu CW and Roth MJ (2003) Role of the mutation Q252R in activating membrane fusion in the murine
leukemia virus surface envelope protein. J.Virol. 2003, Oct; 77(20): 10841. PMID: 14512534
9. Lu CW and Roth MJ (2003) Functional Interaction between the N- and C-terminal domains of murine
leukemia virus surface envelope protein. Virology 310(1):130-40. PMID: 12788637
10. Lu CW, O’Reilly and Roth MJ (2003) G100R mutation within 4070A murine leukemia virus Env
Increases virus receptor binding, kinetics of entry, and viral transduction efficiency. J Virol. 77(1):739-43.
PMID: 12477879
11. Lu CW and Roth MJ (2001) Functional characterization of the N termini of murine leukemia virus
envelope proteins. J Virol. (9):4357-66. PMID: 11287584
12. Lin JS, Lu CW, Huang CJ, Wu PF, Robinson D, Kung HJ, Chi CW, Wu CW, Yang WK, Whang-Peng
JJ, Lin WC. (1998) Protein-tyrosine kinase and protein-serine/threonine kinase expression in human
gastric cancer cell lines. J Biomed Sci. 5(2):101-10. PMID: 9662069 PMID: 12930895
Current Support
1. New Jersey Autism Center of Excellence (co-PI, lead PI James Millonig), July 1st 2013-June 30st 2015. This
project will generate iPS cell lines from 8 pairs of Autism patients with their non-affected siblings for in
vitro studies neuronal phenotypes.
2. NIEHS Center for Environmental Exposure and Disease Pilot project, Sept .1st 2013 – March 31st 2014. This
project studies trophoblast response to common endocrine disrupting chemicals zearalenone and
bisphenol A.
Completer Support
1. Ellison Medical Foundation New Scholar Award in Aging, July 1st 2009-June 30st 2013. $400,000.