Health Canada - Isomer Design

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Health Canada
Santé Canada
STATUS DECISION OF CONTROLLED
AND NON-CONTROLLED SUBSTANCE(S)
Substance: Benzobarbital HCl
Based on the current information available to the Office of Controlled Substances, it appears that
the above substance is:
Controlled
X
Not Controlled
☐
under the schedules of the Controlled Drugs and Substances Act (CDSA) for the following
reason(s):

The substance is a barbiturate and is captured under item 1 of Schedule IV to the CDSA.
Prepared by: _______________________________________
Vincent Marleau
Date: _______________
Verified by:
Date: ________________
_______________________________________
Mark Kozlowski
Approved by: _______________________________________
Date: ________________
DIRECTOR, OFFICE OF CONTROLLED SUBSTANCES
This status was requested by: Melissa Tristani, OCS
2
Drug Status Report
Drug: Benzobarbital HCl
Drug Name Status: Benzobarbital HCl is the common name.
Chemical Name: 1-Benzoyl-5-ethyl-5-phenylpyrimidine-2,4,6-trione hydrochloride
Other Names: 1-Benzoyl-5-ethyl-5-phenylbarbituric acid HCl; Benzobarbitone HCl; Benzonal
HCl.
Chemical structure:
Molecular Formula: C19H16N2O4HCl
CAS-RN: N/A
Pharmacological class / Application: Barbiturate
International status:
US: Benzobarbital HCl is not listed specifically in the Schedules to the US Controlled
Substances Act and is not mentioned anywhere on the DEA website.
United Nations: The substance is not listed on the Yellow List - List of Narcotic Drugs under
International Control, the Green List - List of Psychotropic Substances under International
Control, nor the Red List - List of Precursors and Chemicals Frequently Used in the Illicit
Manufacture of Narcotic Drugs and Psychotropic Substances under International Control.
Canadian Status: Benzobarbital HCl is not listed specifically in the Schedules to the CDSA.
The substance is a salt of benzobarbital, which contains the core structure of the barbiturates.
Currently, “Barbiturates, their salts and derivatives including” are listed as item 1 in Schedule IV
to the CDSA. Given that benzobarbital is a barbiturate, the substance is captured, along with its
salt, under item 1 of Schedule IV to the CDSA.
Recommendation: Benzobarbital HCl is included under item 1 of Schedule IV to the CDSA
and is a controlled substance.
Date: June 18th, 2013.
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