Name: ______________________________ Title: Energy Metabolism Quiz Course: NUTR/HHPN 446 Prof: David L. Gee, PhD Date: April 16, 2007 True (A) and False (B) questions 1. During the 100 meter dash, more than 70% of energy is derived from aerobic metabolism. 2. Studies strongly suggest that the amount of carbohydrates in the diet does not alter the levels of glycogen found in the muscle. 3. "Hitting the wall" or "bonking" refers to : a. sprinters as their muscles are in lactic acidosis b. a popular sport in bars and taverns c. development of ketosis in endurance athletes d. depletion of muscle glycogen in endurance athletes e. amino acid depletion during heavy weight training 4. The most important factor determining which energy system will be used is the intensity of the exercise. 5. The major source of energy during a 400meter run completed in one minute is: a. ketone bodies b. branch chain amino acids c. blood glucose d. creatine phosphate e. muscle glycogen 6. Which of the following is NOT a likely cause of fatigue during exercise. a. depletion of muscle glycogen b. decreased acidity in muscle cells c. increased serotonin levels d. decrease in blood sugar levels e. all of the above have been shown to cause fatigue during exercise. 7. Which of the following has not been associated with causing fatigue due to high intensity exercise. a. depletion of muscle protein stores b. alteration in calcium binding in muscle cells c. decreased binding of actin and myosin d. decreased activity of the rate-limiting enzyme of glycolysis 8. ATP and Creatine phosphate present in resting muscle are the primary source of energy in track events lasting about one minute. 9. Which energy system would predominate in an all-out, high intensity 400 metere dash in track? a. ATP-PC b. lactic acid system c. oxygen-carbohydrate system d. oxygen-fat system e. oxygen-protein system - 2Name: ______________________________ Title: Energy Metabolism Quiz 10. Which ergogenic aid has been linked with increasing the mobilization of fat from fat cells resulting in higher levels of free fatty acids in the blood? a. carnitine b. creatine c. caffeine d. bicarbonate e. branch chain amino acids 11. In their recent consensus paper, the American College of Sports Medicine concluded that oral supplementation of creatine had NO effect on muscular activity in high intensity, repetitive exercise tests. 12. The total amount of energy derived DIRECTLY from total body creatine phosphate is estimated to be____Calories a. 4 b. 40 c. 400 d. 4000 13. Daily training runs of 10 miles will not result in a decline in initial muscle glycogen concentrations the next day if one consumes a diet containing 45-50% of calories from carbohydrate, 20% protein, and 30-35% fat. 14. Depletion of muscle glycogen concentration is associated with higher ratings of perceived exertion. 15. Substantial utilization of muscle glycogen with potential of causing glycogen depletion has been demonstrated in stop and go events like soccer. 16. Successive days of hard training has little effect on preexercise muscle glycogen levels if the athlete consumes a diet containing a minimum of 40% of calories as CHO. 17. The oxygen system: a. produces ATP in large quantities from carbohydrates and fat. b. involves aerobic processing of carbohydrate to some extent with major utilization of protein c. is used primarily in sorts that demand intense exercise d. depends upon reactions that occur only in the cytoplasm of the muscle cell 18. For events lasting up to 5 seconds, the most important source of energy for muscle contraction is: a. blood glucose b. fructose c. fatty acids d. creatine phosphate e. amino acids 19. As the intensity of exercise increases, the percentage of energy derived from fat decreases. - 3Name: ______________________________ Title: Energy Metabolism Quiz 20. During high intensity exercise, _______ serves as the primary terminal electron acceptor during the anaerobic oxidation of glucose. a. oxygen b. pyruvate c. creatine phosphate d. carbon dioxide e. amino acids 21. Bicarbonate loading would be most useful for events lasting: a. less than 1 second b. between 2-10 seconds c. between 10-15 seconds d. between 1-7 minutes e. longer than 1 hour 22. Which of the following energy sources found in the human body represents the greatest storage of potential energy in the form of total calories? a. blood glucose b. ATP c. muscle glycogen d. adipose tissue triglyceride e. muscle protein 23. Which of the energy sources produces ATP at the SLOWEST rate? a. muscle glycogen b. liver glycogen c. creatine phosphate d. blood glucose e. adipose triglycerides 24. Initial muscle glycogen levels in athletes participating in daily intensive physical training (about one hour per day of continuous exercise) while consuming a diet containing 30% carbohydrates by calories will__________. a. increase slightly every day. b. decrease gradually as the week progresses c. will remain essentially unchanged. 25. The total amount of energy derived DIRECTLY from total body glycogen is estimated to be approximately ____ Calories. a. 2 b. 20 c. 200 d. 2000 26. Generally speaking, increased muscle glycogen concentration is associated with a reduction in endurance performance. 27. In one study described in class, soccer players with initially higher levels of muscle glycogen spent more time walking and less time running than players with lower initial levels of muscle glycogen. - 4- Name: ______________________________ Title: Energy Metabolism Quiz 28. The high energy compound directly utilized by muscles to drive muscle contraction is: a. creatine phosphate b. creatinine c. adenosine triphosphate d. glucose e. acetoacetate 29. In the "Central Fatigue Hypothesis", the reduction in plasma branch chain amino acids is thought to result in an increase in which hormone? a. insulin b. glucagon c. valine d. adrenaline e. serotonin 30. The enzyme directly involved in the transfer of energy from creatine phosphate to form ATP is called: a. hormone sensitive lipase b. lactate dehydrogenase c. creatine kinase d. creatinine e. cytochrome oxidase 31. Liver glycogen plays no role in exercise energy metabolism during endurance events. 32. During low intensity exercise, ________ serves as the primary terminal electron acceptor during the aerobic oxidation of fatty acids. a. oxygen b. pyruvate c. creatine phosphate d. carbon dioxide e. amino acids 33. Bicarbonate loading may be ergogenic because of it ability to neutralize lactic acid. 34. Oral supplementation of creatinine has been shown to effectively increase muscle cellular levels of creatine phosphate. 35. Which of the following energy sources produces ATP at the GREATEST rate? a. muscle glycogen b. liver glycogen c. creatine phosphate d. blood glucose e. adipose triglycerides - 5Name: ______________________________ Title: Energy Metabolism Quiz 36. Caffeine is thought to be an ergogenic aid for endurance athlete because of the effect it has on increasing the activity of: a. creatine kinase b. neutral amino acid transport proteins c. anaerobic glycolysis d. electron transport system e. adipose hormone sensitive lipase 37. An increase in the blood concentration of the following may be an indicator of muscle damage. a. lactic acid b. triglycerides c. free fatty acids d. creatine kinase e. glucose 38. The metabolic pathway known as ______ is involved in the lactic acid system. a. Kreb's Cycle b. Electron Transport System c. Glycolysis d. beta-oxidation of fatty acids 39. The enzyme which catalyzes the hydrolysis of triglycerides in fat cells producing fatty acids is called: a. amylase b. creatine kinase c. carnitine transferase d. hormone sensitive lipase e. insulin 40. Lactic acid produced during exercise results from the oxidation of: a. lactose b. glucose c. fatty acids d. ketone bodies e. amino acids 41. Oral supplementation with creatine kinase has been shown to be effective in increasing exercise performance in high intensity, repetitive exercises. 42. During high-intensity, fatiguing exercise in which anaerobic reactions predominate, ___________ is used as the primary source of energy. a. ketone bodies b. muscle glycogen c. blood glucose d. fatty acids e. amino acids 43. During high intensity exercise like weight lifting, protein oxidation for energy production contributes about 40% of energy needs. - 6Name: ______________________________ Title: Energy Metabolism Quiz 44. Generally speaking, metabolic pathways that generate energy are _______ pathways. a. oxidative b. reduction c. anabolic 45. In an experimental study to evaluate the effect of creatine supplementation on muscular power for sport, which of the following would NOT be considered acceptable for the research methodology to be followed in the conduct of the study? a. use well-trained power sport athletes b. use a double blind protocol c. use a placebo control group d. use a sport-related performance task e. use males in one group and females in the other 46. Increasing exercise intensity results in a decrease in the rate of glycogen utilization. 47. Typical intake of dietary creatine is about: a. 1 gram per day b. 10 grams per day c. 100 grams per day d. 1 milligram per day e. 10 milligrams per day 48. The total amount of energy derived DIRECTLY from total body ATP is estimated to be: a. 1 Calorie b. 10 Calories c. 100 Calories d. 1000 Calories 49. After three exhaustive one minute runs, blood lactic acid concentrations remain substantially elevated (about five to six times higher than resting) 30 minutes after completing the last run.