POST-DOCTORAL FELLOWSHIPS (FULL-TIME)
The San Antonio Center for Cardiovascular Systems Biology is recruiting for multiple
immediate postdoctoral fellow positions. Our center is dedicated to performing cardiovascular
research that involves: 1) developing multidimensional approaches to examine the mechanisms
whereby the cardiovascular system responds to stress or injury; 2) applying the knowledge
gained to develop therapeutic strategies to prevent, slow, or reverse the progression of
cardiovascular disease; and 3) disseminating our results to scientific, medical, and general
communities and educating new generations of cardiovascular scientists. Included in our
research program is the UTHSCSA Cardiovascular Proteomics Center, one of 7 proteomic
centers in the nation funded by the NHLBI, and an NIH T32 training program.
Candidates (MD and/or PhD) must have solid experience with contemporary techniques,
preferably with emphasis in cardiovascular biology. Expertise with rodent cardiac surgery,
vascular surgery, proteomics, cell biology, or computational biology approaches is preferred.
Suitable candidates must also have excellent organizational and communication skills, be
enthusiastic about their work, and be highly motivated to succeed. Positions are immediately
available in the laboratories of the following principal investigators:
Seema S. Ahuja, MD: murine models of atherosclerosis, diabetes, and arthritis to explore the
role of chemokines and chemokine receptors in dendritic cells, macrophages and lymphocyte
biology and function.
Hai-Chao Han, PhD: artery and left ventricular tissue remodeling under mechanical stresses.
We use theoretical analysis, computational simulation, and experimental testing to better
understand artery tortuosity, arteriogenesis, and post-myocardial infarction (MI) left ventricular
responses
Yufang Jin, PhD: modeling, computational simulation, and experimental testing of left
ventricular remodeling in response to injury and aging. Our projects also include parameter
estimation and stability analysis of remodeling outcomes using theoretical analysis, analysis of
disease specific protein interaction network and protein-drug interactions.
Claude LeSaux, PhD: pulmonary and cardiac remodeling, caveolin-1 roles in preventing
fibrosis by regulation of transforming growth factor-beta, the relationship between vasculature
structural changes in response to secondary pulmonary hypertension and lung fibrosis in mouse
models and in humans; comparing and contrasting cardiac fibrosis models with lung fibrosis
models
Merry L. Lindsey, PhD: inflammatory and fibrotic responses to MI, focusing on matrix
metalloproteinase (MMP) roles in post-MI left ventricular remodeling. We use techniques in
physiology, pathology, pharmacology, biochemistry, engineering, cell biology, proteomics, and
computational biology to better understand cardiac responses to injury.
Applicants should send a cover letter, curriculum vitae, and a list of at least three (3) references
to: Charlene Loeffler, Senior Research Coordinator, The University of Texas Health Science
Center at San Antonio, email: loeffler@uthscsa.edu.
All postdoctoral appointments are designated as security sensitive positions.
The University of Texas Health Science Center at San Antonio is an
Equal Employment Opportunity/Affirmative Action Employer