Maryam P. Yosri Speech# 5 Outline Topic: Saving lives Specific purpose: To inform and persuade my audience of how can be a bone marrow donor Thesis statement: simplicity and ease of bone marrow donation Introduction I. You can be a cure or be someone’s cure II. Imagine in a sunny afternoon of a summer day, you are hiking, and all of a sudden you hear someone groaning and calling for help. You start walking fast to find the source. You find someone suspended in mid air, holding to a piece of rock. You try to focus, to think what you should do, in the mean time he/she is telling you to bring his/her rope or wood stick. Immediately, you look at your backpack and surprisingly find rope, and you throw the robe to his/her. Wow! You saved him/her. III. How do you feel if each one of you could save a life tonight? IV. Most of you have heard about leukemia; Leukemia is cancer of the blood cells. It starts in the bone marrow, the soft tissue inside most bones. Transition: what cause leukemia? Body I. Experts don’t know what causes leukemia but there are some risk factors, such as: • Exposure to large amounts of radiation. • Exposure to certain chemicals at work, such as benzene. • Having had some types of chemotherapy to treat another cancer. • Having Down syndrome or some other genetic problems. But there is an easy and simple way to save a life or cure leukemia that is called bone marrow transplant. Transition: Having the possible cure for leukemia patients, so why are they dying in large numbers? The hard question to be answered is why people don’t volunteer to save lives? II. In my opinion there are some reasons for lack of donors: 1- Lack of enough knowledge about the cure itself, 2- Lack of knowledge about the process of donation, 3- Hesitancy regarding effects of donation on themselves 4- Most people think bone marrow donation is painful and they have to pay, but it is not true, it is pain free and it doesn’t cost a penny. III. I recently did a research and found out how easy the process is. A. Bone marrow donation used to be a complex process. It was a minor surgery performed under general anesthesia, meaning the donor would be asleep and painfree during the procedure. The bone marrow was removed from the back of both hipbones during this process. B. But today there is an easy and simple way to donate that is called PBSC donation. If you are at the ages between 18-44 provide the greatest chance. Transition: so, what are the steps? The first step is: Go to marrow.org and choose join us to register yourself as a donor. The second step is: answer the question about your overall health The third step is: you will receive a swab kit for collect DNA or check cell, follow the instruction and return the kit. Transition: For how long are you going to be a donor or in the list? When you join to be the match registry, you make a commitment to be listed until your 61th birthday, unless you ask to be removed. About 1 in 540 member of the Be Match Registry in the United States will go to donate bone marrow. Transition: what will happen after the match? After you become a match and picked to donate, you are the only thing between life and death of the recipient. A. The final step is: donate blood cells through PBSC process. PBSC donation is a non-surgical procedure done in an outpatient clinic. PBSC donors receive daily injections of a drug called filgrastim for five days, to increase the number of blood-forming cells in the bloodstream. B. Then, through a process called apheresis, a donor's blood is removed through a needle in one arm and passed through a machine that separates out the blood-forming cells. The remaining blood is returned to the donor through the other arm. Then a donor's healthy blood-forming cells are given directly into the patient's bloodstream, where they can begin to function and multiply. Conclusion I. Every year, 10,000 blood cancer and blood disease patients need a marrow transplant to survive. By making a gift to Be The Match, you help ensure that every patient receives the care and support services they need. II. It is left up to each and everyone of us to help those in need. There hasn’t been a single concern about safety and health of the donors, so the only investment in saving someone’s life is a few hours of our time. III. Can you stand and watch a human being die? If not, then please participate in donor’s program and add a remarkable purpose to your life. Websites: http://www.webmd.com/cancer/tc/leukemia-topic-overview http://www.cancer.gov/cancertopics/types/leukemia http://health.nytimes.com/health/guides/surgery/bone-marrow-transplant/overview.html