2013 Yale Center for Molecular Discovery Pilot Project Program For Molecular Probe Synthesis, Computational Chemistry and Chemical Research Page Limit: 3 pages (Strictly enforced) Applications should be completed in Arial, 10 point font with no modification to page margins. Submit to michael.kinch@yale.edu by July 15, 5:00 PM EDT. Applicant Information: Name: Title: Department: Campus address: Telephone number: Email: Project: Project Title: Name & Affiliation of collaborator(s): Goal: What are the specific goals of the proposed investigation and how do they relate to your long-term goal? (limited to end of page): 2012 CMD Pilot Application Page 1 of 3 I. Research Impact: How might this funding assist your laboratory start a new line of investigation, obtain independent funding or publish? II. Synthetic precedent. For each chemical template, please provide a recent literature citation for synthesis. For each unique compound, please provide a CAS number and chemical structure. For structure-based design, please provide structure information for the target. For assistance, please contact YCMD chemistry (denton.hoyer@yale.edu). 2012 CMD Pilot Application Page 2 of 3 III. Novelty: Is the molecular probe novel or difficult to obtain commercially? Is the chemical research novel? What similar approaches are cited in the literature that suggest the project is feasible? IV. Follow-Up: What are the likely next steps (beyond the funding and research provided) and is the laboratory committed to conduct follow-on investigation? 2012 CMD Pilot Application Page 3 of 3