MICR 434(G)
IMMUNOLOGY
Wendell L. French, Ph.D.
Office: Rm 232
Phone 298-1294
Email: WL-French@wiu.edu
Spring 2013
Office hours: Mon 11 a.m.-12 p.m., Tue 10 a.m.-12 p.m., Wed 11 a.m.-12 p.m.
Lecture (Rm 202): Mon Wed 9:00-9:50 a.m.
Lab (Rm 234): Thursday
Sec. 41 10-11:50 a.m.
SYLLABUS SUBJECT TO CHANGE WITH NOTICE!
Textbooks and other materials:
Kuby IMMUNOLOGY. T. Kindt, R. Goldsby, and B. Osborne. 2007. 6th Edition.
W.H. Freeman and Company, New York
Web site:
Immunology: www.whfreeman.com/immunology6e
American Society for Microbiology: www.asmusa.org/
Center for Disease Control: www.cdc.gov/
WebCT: http://westernonline.wiu.edu = instructions will be given later
Course description:
A study of antigens and antibodies, the immune response and immunity, immunologic testing,
allergy and hypersensitivity, transplantation, autoimmune diseases, and cancer immunology.
Laboratory includes selected immunologic techniques.
Prerequisites: Bot 200, Micr 200, Zool 200, one year of chemistry.
Exams and Grade Scale
Exam 1
Exam 2
Exam 3
Final Exam
Lab Exam
Lab Attendance
50 pts.
50 pts.
50 pts.
50 pts.
50 pts.
28 pts.
(2 pts. for each day present in lab)
Assignments
40 pts.
(10 pts. each)
Quizzes
Lab Exercises
(10 pts. each)
Total Points
20 pts.
70 pts.
______
408 pts.
UNDERGRAD GRADING SCALE
100-93% = A
92-90% = A89-87% = B+
86-83% = B
82-80% = B79-77% = C+
76-73% = C
72-70% = C69-67% = D+
66-63% = D
62-60% = D59% and below = F
GRAD GRADING SCALE
A = 95-100%
B = 85-94%
C = 75-84%
D = 65-74%
F = below 65%
Each exam may include short answer essay, fill-in-the-blanks, multiple choice, true false, or
matching. Exam format will be discussed prior to each exam.
Lab exam: Information and format will be presented before the exam.
Assignments and unannounced/announced quizzes will be given throughout the semester.
Assignments: If you are not present in class the day the assignment is handed out, you will
receive a zero. If you are excused for your absence the day the assignment is
handed out, you will receive the assignment. Assignments are usually given a
week before each lecture exam. All assignments must be submitted by the due
date listed on the assignment instructions.
Unannounced/announced quizzes: If you are not present the day a quiz is given (unannounced
or announced), you will receive a zero. If you are excused
for your absence the day a quiz is given, you will have the
opportunity to take the make-up quiz.
Make-up Exams: Make-up exams will only be given if you provide a valid excuse prior to the
absence or valid documentation after-the-fact.
Late Work Policy: Assignments and written reports (lab exercises) will be docked 10% of their
final grade per day that they are late.
Attendance: In order to get the most out of your education, you are expected to attend
all lectures and labs and to be on time and stay for the entire class period. Attendance for a
course such as this is critical to your understanding of the material. Attendance will be taken at
the beginning of each class period in lecture as well as lab. Note that 2 unexcused laboratory
absences will result in an automatic failure of the course. An excused absence requires
proper documentation: if you are sick, provide me with a doctor’s note; if there is a family
death, provide me with appropriate funeral documentation. Undocumented absences are
considered unexcused by the University. Any combination of two incidences of coming to lab
late and/or leaving lab early will be considered and treated as an unexcused absence.
Lecture exams will cover material presented in the text and in lecture. Notes for lectures will be
available on WebCT Vista after the completion of each lecture unit. Access to WebCT Vista is
available at: http://westernonline.wiu.edu/
CHEATING AND PLAGIARISM WILL NOT BE TOLERATED.
Definition of Plagiarism
The faculty of the Department of Biological Sciences ascribes to a definition of plagiarism as
expressed by V. E. McMillan in Writing Papers in the Biological Sciences (Bedford/St.Martin’s
Press, New York, pg 16)
“Plagiarism is the theft of someone else’s words, work, or ideas. It includes such acts as (1)
turning in a friend’s paper and saying it is yours; (2) using another person’s data or ideas
without acknowledgement; (3) copying an author’s exact words and putting them in your
paper without quotation marks; and (4) using wording that is very similar to that of the
original source but passing it off as entirely your own even while acknowledging the source.”
This includes information in textbooks or laboratory manuals, honors and masters theses, all
writing assignments, and images. The faculty of the Department attempt to monitor student
writing assignments (essay exams, papers, laboratory reports, and other writing assignments or
exercises) for incidence of plagiarism. If plagiarism is found, the faculty will discuss the
situation with the student and indicate to the student the penalty for this academic dishonesty.
Potential penalties include those cited in the academic dishonesty section of the WIU web page.
Students with Disabilities:
"In accordance with University policy and the Americans with Disabilities Act (ADA), academic
accommodations may be made for any student who notifies the instructor of the need for an
accommodation. For the instructor to provide the proper accommodation(s) you must obtain
documentation of the need for an accommodation through Disability Resource Center (DRC) and
provide it to the instructor. It is imperative that you take the initiative to bring such needs to the
instructor's attention, as he/she is not legally permitted to inquire about such particular needs of
students. Students who may require special assistance in emergency evacuations (i.e. fire,
tornado, etc.) should contact the instructor as to the most appropriate procedures to follow in
such an emergency. Contact Disability Resource Center at 298-2512 for additional services."
“Be Respectful” Policy: Be respectful in class. Please do not disturb other students by talking
unnecessarily, reading the paper, passing notes, doing homework for another course, etc. during
the class. PLEASE TURN OFF ALL CELL PHONES, BEEPERS, AND OTHER
ELECTRONIC DEVICES DURING CLASS. If you repeatedly disturb the class with talking,
your cell phone, etc., I will ask you to leave the class. Come to class on time and stay until the
end. If you have a hard time hearing me, please don’t hesitate to ask me to talk louder, or move
your seat as you need to be able to hear better.
It is the student’s responsibility to be familiar with the information (including required forms,
definitions, and time lines) contained in the following university web sites. Each student should
access these web sites and carefully read the information they contain, your instructors will hold
you responsible for knowing this information. If you have questions about any of the
information contained in the web sites, ask your instructor:
Department of Biological Sciences Policies:
http://www.wiu.edu/biology/about/policies.shtml
Student Rights and Responsibilities:
http://www.wiu.edu/provost/student/
Final Exam Policy:
http://www.wiu.edu/policies/finexam.php
Academic Integrity Policy:
http://www.wiu.edu/policies/acintegrity.php
Grade Appeals Policy:
http://www.wiu.edu/policies/gradeapp.php
STATE ACCREDITATION POLICY INFORMATION:
“In accordance with Illinois State Board of Education certification rules, all candidates seeking teacher
certification are required by Western Illinois University to obtain a grade of “C” or better in all directed
general education course, all core courses, and all courses in the option. Note: A “C- ” is below a “C”.”
Please note: any secondary science teacher certification student wanting to see how this course is aligned
with the State and National Standards should see their advisor and/or examine the Secondary Science
Teacher Certification WesternOnline Advising site.
SEE NEXT PAGE FOR CLASS SCHEDULE.
MICR 434(G)
IMMUNOLOGY
CLASS SCHEDULE
Instructor: Wendell L. French, Ph.D.
Spring 2013
Date
Unit; Chapter
Topic
1/14
1/16
1/17
Historical Aspects of Immunology
Introduction to Immunology
Lab: No Lab
1/21
1/23
1/24
NO CLASSES DR. M.L. KING JR. DAY
Introduction to Immunology
Lab: Movie (The Fighting Edge)
1/28
1/30
1/31
Immunocytology
Immunocytology
Lab: Salmonella agglutination
Unit 3; 2
Unit 3; 2
2/4
2/6
2/7
Immunocytology
Immunocytology
Lab: Immunocytology (Blood Cells of the Immune System)
Unit 3; 2
Unit 3; 2
2/11
2/13
2/14
Antigens
Antigens
Lab: Exam 1
Unit 4; 4
Unit 4; 4
2/18
2/20
2/21
Immunoglobulins and Antibody Diversity
Unit 5; 4, 5
Immunological Techniques
Unit 6; 6
Lab: Immunocytology (Lymphoid Tissue of the Immune System)
2/25
2/27
Immunological Techniques
Major Histocompatibility Complex and
Antigen Processing and Presentation
Lab: Radial Immunodiffusion
Unit 6; 6
Unit 7; 8, 9
3/4
3/6
3/7
Cytokines
Cell-Mediated Immune Response
Lab: Results and Discussion on Radial Immunodiffusion;
Detection of Epstein-Barr virus (EBV) using ELISA
Unit 8; 12
Unit 9; 10, 14
3/11-3/15
3/18
3/20
3/21
SPRING BREAK
Cell-Mediated Immune Response
B-Cells and the Immune Response
Lab: Exam 2; Results and Discussion for the Detection of EBV
using ELISA
2/28
Unit 1; 1
Unit 2; 1, 3
Unit 2; 1, 3
Unit 9; 10, 14
Unit 10; 11
3/25
3/27
3/28
Complement System
Complement System
Lab: Simulated Detection of HIV-I using the
Enzyme-linked immunosorbent assay (ELISA)
Unit 11; 7
Unit 11; 7
4/1
4/ 3
4/4
Inflammation
Hypersensitivity (Allergies)
Lab: Results and Discussion for Simulated
Detection of HIV-1 by ELISA
Unit 12; 13
Unit 13; 15
4/8
4/10
4/11
Hypersensitivity (Allergies)
Immune Response to Infectious Diseases
Lab: Simulated Detection of HIV-1 by Western Blot
(Agarose-based)
Unit 13; 15
Unit 14; 18
4/15
4/17
4/18
Immune Response to Infectious Diseases
Immunodeficiency Diseases
Lab: Exam 3, Results and Discussion for Simulated Detection of
HIV-1 by Western Blot (Agarose-based)
Unit 14; 18
Unit 15; 20
4/22
4/24
4/25
Immunodeficiency Diseases
Autoimmunity
Lab: Lab Review
Unit 15; 20
Unit 16; 16
4/29
5/1
5/2
Transplantation Immunology
Cancer and the Immune Response
Lab: Laboratory exam
Unit 17; 17
Unit 18; 21
5/8
Final Exam Wednesday, 8-9:50 AM Rm. 202
SYLLABUS SCHEDULE SUBJECT TO CHANGE WITH
NOTICE!