Supplemental document 2
Supplemental document: Studies that were included in the final review, identified from the generic and
specific literature searches
Supplemental table 1: Studies identified by both the generic and specific searches
Author, date
Title
Journal
Health outcome
Design
Appraisal score1
Country
(+ = higher scoring)
Gordon et al, 2004
1
Petersen et al, 2003
2
Prevalence of reported migraine
Canadian Journal of
Migraine.
Cross-
headaches in Canadian
Neurological
adolescents.
Sciences
High prevalence of tiredness and
Scandinavian
Backache; headache;
Cross-
pain in young school-children.
Journal of Public
stomach ache; tiredness.
sectional
Chest pain; cold sweat;
Cross-
dizziness; fatigue;
sectional
7
Canada
9 (+)
Sweden
8 (+)
USA
sectional
Health
Rhee et al, 2005
3
Prevalence of recurrent physical
Pediatric Nursing
symptoms in US adolescents.
feeling hot; frequent sore
throat/cough; headache;
stomach ache;
musculoskeletal pain;
painful/frequent
urination.
1
Note: appraisal score criteria and range varied by study design – see protocol.
1
Supplemental document 2
Supplemental table 2: Studies identified by the generic health search only.
Author, date
Title
Journal
Health Outcome
Design
Appraisal score1
Country
(+ = higher scoring)
Bigal et al, 20074
Migraine in adolescents:
Neurology
Migraine.
Association with socioeconomic
Cross-
6
USA
7
Austria, France,
sectional
status and family history.
Bisegger et al, 2005
5
Health-related quality of life:
Sozial- und
Health related quality of
Cross-
gender differences in childhood
Praventivmedizin
life.
sectional
Germany, Spain,
and adolescence.
Switzerland, UK ;
Netherlands
Cavallo et al, 20066
Girls growing through
Quality of Life
Backache; difficulties in
Cross-
adolescence have a higher risk of
Research
sleeping; feeling dizzy;
sectional
poor health.
9 (+)
Europe and North
America
feeling low; feeling
nervous; headache;
irritability and bad
temper; self-rated health;
stomach ache.
*Gadin &
Hammarstrom, 2000
7
School-related health – A cross-
International
Abdominal pain;
Cross-
sectional study among boys and
Journal of Health
backache; headache;
sectional
girls.
8
Sweden
nausea; self-worth;
2
Supplemental document 2
Services
stress; tiredness.
Longitudinal investigation of low
Physiotherapy
Low back pain.
Longitudinal
6
Australia
back pain in Australian
Research
adolescents: a five-year study.
International
*Haugland et al,
Subjective health complaints in
European Journal of
Abdominal pain;
Cross-
11 (+)
Finland, Norway,
20019
adolescence. A cross-national
Public Health
backache; dizziness;
sectional
Grimmer et al, 20068
comparison of prevalence and
feeling low; feeling
dimensionality.
nervous; headache;
Poland and Scotland
irritability or bad mood;
sleeping difficulties.
Holmberg, &
Age-related gender differences of
International
Abdominal pain; feeling
Cross-
Hellberg, 200710
relevance for health in Swedish
Journal of
depressed; feeling
sectional
adolescents.
Adolescent
healthy; headache;
Medicine & Health
suicidal thoughts.
Jorngarden et al,
Measuring health-related quality
Health & Quality of
Anxiety; depression;
Cross-
200611
of life in adolescents and young
Life Outcomes
health related quality of
sectional
adults: Swedish normative data
8
Sweden
5
Sweden
5
Sweden
life.
for the SF-36 and the HADS, and
the influence of age, gender and
method of administration.
Kujala et al, 1999
12
Leisure physical activity and
British Journal of
Abdominal pain;
Cross-
various pain symptoms among
Sports Medicine
headache; lower back
sectional
adolescents.
pain; lower limb pain;
neck and shoulder pain;
upper back pain; upper
3
Supplemental document 2
limb pain.
Laaksonen et al,
The change in child self-assessed
Scandinavian
Health related quality of
201013
and parent-proxy assessed health
Journal of Public
life.
related quality of life in early
Health
Longitudinal
10
Finland
Cross-
8
Norway
8
Norway
9 (+)
Sweden
Longitudinal
7
Spain
8
Germany
11
Cyprus
adolescence (age 10-12).
Lundqvist et al,
2006
Self-reported headache in
14
Acta Paediatrica
Headache.
schoolchildren: parents
sectional
underestimate their children’s
headaches.
Meland et al, 2007
15
Ostberg et al, 200616
Body image and perceived health
Health Education
Body image; perceived
Cross-
in adolescence.
Research
health.
sectional
Living conditions and
Acta Paediatrica
Difficulties falling
Cross-
psychosomatic complaints in
asleep; headache;
sectional
Swedish schoolchildren.
stomach ache.
Palacio-Vieira et al,
Changes in health-related quality
Quality of Life
Health related quality of
200817
of life in a population-based
Research
life.
sample of children and
adolescents after 3 years followup.
Ravens-Sieberer et
Health-related quality of life in
European Child &
Health related quality of
Cross-
al, 200818
children and adolescents in
Adolescent
life.
sectional
Germany: results of the BELLA
Psychiatry
Type 1 diabetes mellitus.
Routine data
study.
Skordis et al, 200219
The incidence of type 1 diabetes
Pediatric Diabetes
mellitus in Greek-Cypriot
children and adolescents in 1990-
4
Supplemental document 2
2000.
Sleskova et al,
Health status among young
Social Science &
Health complaints
Cross-
200520
people in Slovakia: comparisons
Medicine
(backache; bone/muscle
sectional
on the basis of age, gender and
ache; breathlessness;
education.
chest/heart pain;
7
Slovakia
11 (+)
Sweden
12 (+)
Scotland
dizziness; full/bloated
stomach; headache;
listlessness; pins and
needles; tiredness;upset
stomach); mental health;
long-standing illness;
long-term wellbeing;
self-rated health; vitality.
Sundblad et al,
Prevalence and co-occurrence of
European Journal of
Abdominal pain;
Cross-
200721
self-rated pain and perceived
Pain
headache; loneliness;
sectional
health in school-children: age and
musculoskeletal pain;
gender differences.
problems sleeping;
sadness; tiredness.
*Sweeting & West,
2003
22
Sex differences in health at ages
Social Science &
Depression; general
11, 13 and 15.
Medicine
health; recent symptoms
Longitudinal
(aching back, legs or
arms; asthma or wheeze;
cold or flu; difficulty
getting to sleep; dizzy or
faint; headache; irritable
or bad tempered;
5
Supplemental document 2
nervous, worried or
anxious; sad, unhappy or
low; spots, rashes or
other skin problems;
stomach ache or feeling
sick).
*Torsheim et al,
2006
23
Cross-national variation of gender
Social Science &
Health complaints
Cross-
differences in adolescent
Medicine
(backache; depressed
sectional
subjective health in Europe and
mood; dizziness;
North America.
headache; irritable;
9 (+)
Europe and North
America (29
countries)
nervousness; stomach
ache; sleeping
difficulties).
Wedderkopp et al,
Back pain reporting pattern in a
200124
Danish population-based sample
Spine
Back pain; neck pain.
Cross-
8
Denmark
sectional
of children and adolescents.
*Studies that were also identified through manual searching
6
Supplemental document 2
Supplemental table 3: Studies identified by the specific health search only
Author, date
Title
Journal
Health outcome
Design
Appraisal score1
Country
(+ = higher scoring)
Beilmann et al,
199925
Carle et al, 2004
26
Incidence of childhood epilepsy
Brain &
Epilepsy.
Routine data
12 (+)
Estonia
in Estonia.
Development
Diabetes incidence in 0 to 14-year
Diabetes Care
Type 1 diabetes mellitus.
Routine data
12 (+)
Italy
Diabetes Care
Type 1 diabetes mellitus.
Routine data
10
Sardinia
Epilepsy Research
Epilepsy.
Routine data
9
Denmark
Diabetic Medicine
Type 1 diabetes mellitus.
Routine data
11
Czech Republic
age group in Italy. A 10-year
prospective study.
Casu et al, 2004
27
Type 1 diabetes among Sardinian
Children is increasing. The
Sardinian diabetes register for
children aged 0-14 years (198891999).
Christensen et al,
2007
28
Cinek et al, 200029
Incidence and prevalence of
epilepsy in Denmark.
Type 1 diabetes mellitus in Czech
children diagnosed in 1990-1997:
a significant increase in incidence
and male predominance in the age
group 0-4 years.
7
Supplemental document 2
Cotellessa et al,
2003
High incidence of type 1 diabetes
30
Diabetes Care
Type 1 diabetes mellitus.
Routine data
11
Italy
Epilepsia
Epilepsy.
Routine data
10
Germany
Cephalalgia
Headache; migraine.
Cross-
9 (+)
Germany
in Liguria Italy, from 1989 to
1998.
Freitag et al, 2001
31
Incidence of epilepsies and
epileptic syndromes in children
and adolescents: a populationbased prospective study in
Germany.
Heinrich et al, 200932
Self-report of headache in
children and adolescents in
sectional
Germany: possibilities and
confines of questionnaire data for
headache classification.cha_1812
Karvonen et al,
1999
The onset age of type 1 diabetes
33
Diabetes Care
Type 1 diabetes mellitus.
Routine data
11
Finland
Headache
Headache.
Longitudinal
10
Norway
Cephalalgia
Headache; migraine.
Cross-
8
Sweden
5
Sweden
in Finnish children has become
younger.
Larsson & Sund,
2005
One-year incidence, course and
34
outcome predictors of frequent
headaches among early
adolescents.
Laurell et al, 2004
35
Prevalence of headache in
Swedish schoolchildren, with a
sectional
focus on tension-type headache.
Leonardsson-
Headache and associations with
Scandinavian
Hellgren et al, 200136
lifestyle among pupils in senior
Journal of Primary
level elementary school.
Health Care
Headache.
Crosssectional
8
Supplemental document 2
Mavromichalis et al,
1999
37
Prevalence of migraine in
Headache
Migraine.
schoolchildren and some clinical
Cross-
9 (+)
Greece
sectional
comparisons between migraine
with and without aura.
Michalkova et al,
Incidence and prevalence of
199538
childhood diabetes in Slovakia
Diabetes Care
Type 1 diabetes mellitus.
Routine data
11
Slovakia
Headache; migraine.
Cross-
6
UK
5
UK
9 (+)
Italy
(1985-1992).
*Mortimer et al,
Epidemiology of headache and
Developmental
199239
childhood migraine in an urban
Medicine and Child
general practice using ad hoc,
Neurology
sectional
Vahlquist and IHS criteria.
Mortimer et al,
1993
40
Santinello et al,
2008
41
Clinical epidemiology of
Developmental
Abdominal migraine;
Cross-
childhood abdominal migraine in
Medicine and Child
headache; recurrent
sectional
an urban general practice.
Neurology
abdominal pain.
Primary headache in Italian early
Headache
Headache.
adolescents: the role of perceived
Crosssectional
teacher unfairness.
* This study was also referenced in a different publication identified via the generic ELS.
9
Supplemental document 2
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12