Title: A Global Flood Risk Initiative: Climate Informed Dynamic Risk Measures – Upmanu Lall Abstract: Mega-floods, that result from persistent precipitation over multiple days and over large regions, are often related to tropical moisture exports connected to very specific atmospheric circulation patterns. Often, multiple floods in the same locations across years, and across multiple locations in the same season, correspond to such identifiable patterns. These observations provide an opportunity to explore whether or not such mechanisms are predictable or if they provide a pathway for flood risk estimation from selected attributes identified from dynamical models of ocean-atmosphere-land hydrology. Prospects and early analyses in this direction are reviewed, and formalized into a perspective towards an end to end dynamic flood risk modeling initiative that connects potential exposure, losses, and infrastructure into a global tool for hazard analysis and mitigation.