BIOL 116 GENES: THE FOUNDATIONS OF LIFE Course Syllabus Spring 2003 Section 116-03 T/R 2:00 pm-3:15pm Room: ICB 2705 This course is an introduction to technological advances in genetics. Scientific principles are emphasized, as well as current and possible future applications. Ethical analyses are included due to the controversial nature and far-reaching effects these technologies have on the individual and society. Catalog Description: 3 semester hours. Introduction to genetics. Scientific principles, applications, and ethical implications of DNA fingerprinting, genetic engineering, and the human genome project are emphasized. Life science lab credit can be obtained by current or subsequent enrollment in BIOL 117. Instructor: Aaron Tomlinson * Email: (Aaront@hcc.cc.il.us) Office hours: By appointment and/or after class. Departmental Mailbox: Located in the Math/Science Department offices. Go to SCB 2400. Enter the glass doors, and Politely ask Dee Armstrong (Right desk) to place whatever into my mailbox. Math/Science phone number: 241—8672 LAST RESORT: My Home phone # : (309) 661—2329 116 Website: http://hcc.cc.il.us/staff/StacieC. Then click on the BIOL 116 link. OR Students can go through the HCC main website (http://www.hcc.cc.il.us ) - click on Employees - Stacie R. Chismark – BIOL 116 link. Course Materials: (Optional text) Human Genetics Concepts and Applications, 4th Ed. 2001. Ricki Lewis. WCB McGrawHill Publ. (Required) BIOL 116 Lecture Guide: Located on the BIOL 116 Lecture Guide website above. BIOL 116 Study Guide. Relationship to Academic Development Programs and Transfer: The course fulfills general education IAI life science lecture credit toward the A.A. and A.S. degrees. IAI Life science lab credit can be obtained by enrollment in BIOL 117. FYI: BIOL 117 is a separate course providing the student with life science lab credit. Students may enroll in BIOL 117 during the same semester as BIOL 116 or any semester after successful completion of BIOL 116. BIOL 117 is offered during the fall, spring, and summer semesters. The summer session is particularly useful for students who plan to take other regular summer school courses. It is a condensed mini-mester scheduled the two weeks between the spring and summer sessions. It is concentrated into two weeks rather than the usual 16. 1 Course Objectives 1. To understand cellular structures, functions, and biological organization. 2. To obtain basic knowledge of the structure and functions of proteins and nucleic acids. 3. To understand scientific principles of DNA typing and case studies. 4. To gain knowledge of complex traits, including behavior, and the dynamic relationship between genes and environment. 5. To attain knowledge of selected genetic disorders. 6. To obtain knowledge of genetic engineering techniques and applications, including gene therapy and cloning. 7. To gain knowledge of the Human Genome Project, and its implications concerning ethics and public policy. Course Outline: I. Mendelian Genetics II. Cells III. The Structure of DNA IV. The Functions of DNA V. The Human Genome Project VI. DNA Fingerprinting VII. Complex Traits VIII. The Genetics of Sex IX. Viruses and Bacteria X. Genetic Engineering XI. Gene Therapy XII. Cloning Student Responsibilities: 1. Students must take responsibility for their own learning. Part of that responsibility is attendance and active participation in all lecture and group sessions. Remaining alert, taking notes during lecture, asking pertinent questions, and completion of assignments are a part of that participation. The student must read and spend enough time in independent study to master the material. If the student is having difficulty with a particular topic, it is his or her responsibility to ask questions or consult with the teacher. Tutors may be available at the ASC. 2. Students must review the syllabus periodically to refresh their memory concerning information provided therein. 3. Students must exhibit courtesy and respect for their fellow students, as well as the instructor. Inappropriate talking or behavior during class will not be tolerated. This is disruptive to the instructor and other students. ONE warning may be given, but is not required. Thereafter, the student(s) will be asked to leave the class. 4. Students must access the BIOL 116 website for required readings and materials. Students are required to print Lecture Guide outline documents and bring them to pertinent lectures. HCC Open Computing Lab is in the library. 5. Students should complete the Study activities prior to exams. This will help with testing your understanding of the material. But, this is just a guide. 6. It is your responsibility to attend lectures or, if absent, get notes from a classmate. I will not give out my lecture notes. 2 Course Policies 1. To ensure fair and equal evaluation, students are required to read the syllabus and sign a contract stating that they understand and will abide by the syllabus policies. If for some reason a student cannot abide by these policies, he/she should not sign the contract and must contact the instructor immediately. 2. Policies on Exams: Accommodations for emergencies: If you miss one exam because you are sick, attending a funeral, in a coma, have been kidnapped, going on a trip, miss your bus, your car breaks down, etc., the exam grade will be dropped without penalty. ONLY USE THIS OPTION IN CASE OF AN EMERGENCY. A poor grade on a previous exam is not an excuse to make up a missed exam. No makeup exams will be given. A comprehensive, essay, final exam may be substituted for a second missed exam. A zero will be recorded for any further missed exams. Exception to the above policy: The last regular exam cannot be dropped without penalty. If the last regular exam is missed, it can only be made up with the comprehensive final. If the last regular exam is your lowest grade (anything over a Zero percent), It will become the exam that is dropped. If you are able to take all 5 regular exams, your lowest exam grade will be dropped. If you miss an exam, it is a zero percent and is therefore your lowest exam grade… ANY QUESTIONS??? Cheating will result in an automatic “F” in the course, no exceptions. 3. Policies on Assignments: Some assignments may be group projects, and therefore requiring attendance and participation. These assignments may involve several lecture periods. If a student does not attend all applicable lecture periods, 75% of the project grade will be deducted. The remaining 25% only will be awarded if the appropriate material is turned in on time. 4. Policies on Attendance: Regular attendance is important for academic success. This is especially true in science where one lecture builds upon information from previous lectures. You should plan to attend every lecture. Don’t schedule appointments during class time; do not take vacations during scheduled class days of the semester. Work towards the goal of getting an “A” in this class. If you need to miss class, it is your responsibility to get the notes from a classmate. I do not give out my notes. 5. Policies on Tardies: Scheduled class times reflect the start of the lecture, not when students should walk through the door. Tardies are disruptive. Please let the instructor know if there are extenuating circumstances which would cause regular lateness or absences. Also, Attendance and tardies may be used to evaluate borderline grades. 6. Syllabus disclaimer This syllabus is subject to change. It is your responsibility to attend lectures or, if absent, contact the instructor for any verbal or written changes. These changes may include dates of lectures, projects or exams, due dates of assignments, and the addition of assignments or quizzes. Student Evaluation Grading scale: 90-100% 80-89% 70-79% 60-69% below 59.5% A B C D F 3 Assignments and Exams Total Points Possible 6 regular Exams (100pt. each, one dropped) Assignment on the Human Genome Project Total: 500pt. 60pt. 560pt. Following these steps will assist the student in achieving success: 1. Attend every lecture, and take exams as scheduled. 2. Bring appropriate materials to lecture. 3. Take thorough notes in lecture. If absent, obtain copies of the notes from another student; the instructor will never give out lecture notes. 4. Complete assignments, using the required format, and turn them in on time. 5. Study often and early for exams. Complete the Study Guides. 6. Write down questions to ask before the lectures and exams. 7. Attend and participate equally in group-projects. 8. Do not procrastinate. 9. Get a minimum of 6 hours sleep every night (especially before an exam)! Academic Integrity Academic integrity is a fundamental principle of collegial life at Heartland Community College and is essential to the credibility of the College’s educational programs. Moreover, because grading may be competitive, students who misrepresent their academic work violate the right of their fellow students. The College, therefore, views any act of academic dishonest as a serious offense requiring disciplinary measures, including course failure, suspension, and even expulsion from the College. In addition, an act of academic dishonesty may have unforeseen effects far beyond any officially imposed penalties. Violations of academic integrity include, but are not limited to cheating, aiding or suborning cheating or other acts of academic dishonesty, plagiarism, misrepresentation of data, falsification of academic records or documents and unauthorized access to computerized academic or administrative records or systems. Definitions of these violations may be found in the college catalog. Plagiarism Plagiarism is the presenting of others’ ideas as if they were your own. When you write a paper, create a project, do a presentation or create anything original, it is assumed that all the work, except for that which is attributed to another author or creator, is your own. Plagiarism is considered a serious academic offense. Note that word-for-word copying is not the only form of plagiarism. Many plagiarism problems can be remedied by citing the sources of the original work. When in doubt, cite the source according to the style your instructor directs. Usually this is APA or MLA Style. Don’t be daunted by citing sources which are not books. You can cite everything – including pamphlets, maps, cereal boxes, telephone conversations, movies, television shows, Internet and world-wide web sites. Most cases of plagiarism arise from carelessness or haste. Violators often attempt to excuse themselves by saying that they were not told of the nature of plagiarism. You have been told. You must not include either the phrases or ideas of another writer in your papers without acknowledgment. Otherwise, you are stealing. Plagiarism is dishonest. It is cheating and is subject to severe penalties. It may endanger your whole career. Don’t do it. 4 Support Services: Heartland Library Information www.hcc.cc.il.us/library Tutoring and Academic Support Heartland Community College offers learning assistance in various forms at no cost to Heartland students at the Academic Support Center (ASC) in Bloomington and at the Pontiac and Lincoln Centers. Tutors are available at convenient times throughout the week. Study groups, group tutoring facilitated by a speciallytrained tutor, are also available by request. Help is also provided through instructional materials, study skills workshops, open computing, and the Library. Tentative Lecture Calendar On-line readings should be accessed through http://hcc.cc.il.us/staff/StacieC. Then click on the BIOL 116 link. Text references below refer to Human Genetics Concepts and Applications. Date Week 1 1/14, 1/16 Week 2 1/21, 1/23 Week 3 1/28, 1/30 Readings & Assignments Lecture Topic Introduction to Course. Mendelian Genetics Lecture Guide: The Cell. Text: Chap. 1, 2. Contract Due. Lecture Guide: The Cell. Gregor Mendel Cells: the smallest life. EXAM 1 (Mendel & Cells). Structure determines function! To understand what DNA does, we have to know what it is. Lecture Guide: Structure of DNA. Text: Chap. 8. Week 4 2/4, 2/6 Week 5 2/11, 2/13 Lecture Guide: Structure of DNA Video: Basic Chemistry for Biology Lecture Guide Functions of DNA. Text: Chap. 9. Lecture Guide Functions of DNA. Week 6 2/18, 2/20 EXAM 2 (Structure & Functions of DNA). What does DNA do? 1) DNA is copied for future generations through DNA replication. 2) Genes in the DNA determine what proteins are produced through protein synthesis. Lecture Guide: Meiosis Text: Chap. 3 Week 7 2/25, 2/27 Every individual's DNA is unique: Meiosis and Sexual Reproduction. Lecture Guide: Meiosis Lecture Guide: DNA Typing Introduction. Text: Chap. 12 (DNA Polymorphisms). DNA Typing History. 5 Week 8 3/4, 3/6 Lecture Guide: DNA Typing Introduction. EXAM 3 (Meiosis & DNA Typing Introduction). 3/11-3/15 Midterm Break Week 9 3/18, 3/20 Lecture Guide: DNA Typing Procedures. DNA Typing: PCR – Dot Blot and STRs Week 10 3/25, 3/27 Lecture Guide: DNA Typing Procedures Lecture Guide: Interpreting DNA Typing DNA Typing: PCR –STRs; Week 11 4/1, 4/3 EXAM 4 (Procedures & Interpreting of DNA Typing). Week 12 4/8, 4/10 Week 13 4/15, 4/17 Week 14 4/22, 4/24 Lecture Guide: Applications of DNA Typing Case studies. Lecture Guide: Applications of DNA Typing Lecture Guide Complex Traits Text: Chap. 7. Lecture Guide: Genetics of Sex. Text: Chap. 6. Interplay between the genes and the environment. EXAM 5 (Applications of DNA Typing, Complex Traits, & Genetics of Sex). Inserting genes into plants and animals, applications of genetic engineering. Week 15 4/29, 5/1 Week 16 5/6, (5/8) Lecture Guide: Genetic Engineering. Lecture Guide: Gene Therapy. Lecture Guide: Gene Therapy. Lecture Guide: Cloning. EXAM 6 (Genetic Engineering, Gene Therapy, & Cloning). Replacing bad genes with good. Cloning animals and humans. Final Exam: Tuesday, May 13; 2:00pm. 6 BIOL 116 Genes: The Foundations of Life Spring 2002, 116-02 Student Contract You must sign this form before the instructor will record any grades. I, (print your name) , read, understand, and will abide by the policies listed below as stated in the lecture and laboratory syllabi. Signature: Date: 1. Student Responsibilities 2. Course Policies concerning… a. Regular Exams b. Accommodations for missed exams b. Cheating and Academic Integrity c. Attendance & Participation for HGP Projects d. Regular Attendance and Tardies 3. Instructor Option of Withdrawl after Four Absences 4. Required Course Materials: Reading Material and Lecture and Study Guides 5. Syllabus disclaimer 6. Course Objectives 7. Student Evaluation 8. Steps will assist the student in achieving success. 9. Support Services 10. Lecture Calendar and Due Dates 11. BIOL 116 website 7