EMBO Global Exchange Lecture Course
on
Molecular and Evolutionary Genetics of Malaria
(21st November - 4th December, 2010)
National Institute of Malaria Research, New Delhi
Program
(All scientific lectures will be of ~45 minutes duration followed by ~ 15 minutes discussions)
21 November, 2010 (Sunday)
Time
09:00 – 18:00
18:00 – 19:00
19:00 – 20:30
Activities
Arrival of all the participants and speakers
Introductory session
Dinner
Organizer/Speaker
Aparup Das
22 November, 2010 (Monday)
Time
09:00 – 09:30
09:30 – 10:30
10:30 – 11:00
11:00 – 12:00
12:00 – 13:00
13:00 – 15:00
15:00 – 16:00
16:00 – 16:30
16:30 – 17:30
17:30 – 18:30
18:30 – 19:00
19:00 – 20:30
Activities
Registration
Inaugural ceremony
Plenary Lecture: Malaria in India: Challenges and
prospects
High Tea
Lecture: Population genomic approaches to map recent
positive selection – Part I
Lunch and Poster Session
Lecture: Epidemiological modeling - An introduction
Tea Break
Lecture: Malaria in India: Spatiotemporal description
and modeling
Lecture: Technological overview of next generation
sequencing
Group Discussions
Dinner
Organizer/Speaker
Virendra K. Dua
Aditya P. Dash
Wolfgang Stephan
Somdatta Sinha
Somdatta Sinha
Anuj Gupta
Aparup Das
Page 1 of 5
23 November, 2010 (Tuesday)
Time
10:00 – 11:00
11:00 – 11:30
11:30 – 12:30
12:30 – 14:30
14:30- 15:30
15:30-16:30
16:30 – 17:00
17:00 – 18:00
18:00 – 19:00
19:00 – 20:30
Activities
Lecture: Next-generation sequencing
Tea Break
Lecture: Genomic space, repetitive DNA sequences, RNA and
immune response
Lunch and Poster Session
Lecture: Genetic complexity of the malaria vectorial system
and malaria control
Lecture: Molecular phylogenetics of Anopheles subgenus
Cellia (Diptera: Culicidae) inferred from nuclear and
mitochondrial DNA sequences
Tea Break
Lecture: Severe malaria: more questions than answer to the
process
Group Discussion/ Journal Club
Dinner
Organizer/Speaker
Jane Carlton
Pramod C. Rath
Kenneth Vernick
Rupenangshu K. Hazra
Manoranjan Ranjit
Aparup Das
24 November, 2010 (Wednesday)
Time
10:00 – 11:00
11:00 – 11:30
11:30 – 12:30
12:30 – 14:30
14:30 – 15:30
15:30 – 16:30
16:30 – 17:00
17:00 – 18:00
18:00 – 19:00
19:00 – 20:30
Activities
Lecture: Population genomic approaches to map recent
positive selection – Part II
Tea Break
Lecture: Genetic and functional dissection of malaria
susceptibility in Anopheles gambiae
Lunch and Poster Session
Lecture: Malaria vector control: Perspectives for future
Lecture: Partial analysis of the Plasmodium falciparum
transcriptome from adult patients suffering from severe
malaria manifestations:
Tea Break
Lecture: Molecular identification and distribution of main
malaria vectors in the central-west highland, Vietnam
Group Discussion/ Journal Club
Dinner
Organizer/Speaker
Wolfgang Stephan
Kenneth Vernick
Kamaraju Raghavendra
Ashis K. Das
Ngo Thi Huong
Aparup Das
25 November, 2010 (Thursday)
Time
10:00 – 11:00
11:00 – 11:30
11:30 – 12:30
12:30 – 14:30
14:30 – 16:30
16:30 – 17:00
Activities
Lecture: Anopheles mosquitoes: Malaria vectors in Southeast
Asia
Tea Break
Lecture: The evolution of drug resistance
Lunch and Poster Session
Practical: DNA isolation and PCR amplification of genes in
malaria Parasites/Vectors/Humans
Tea Break
Organizer/Speaker
Uraiwan Arunyawat
Cally Rooper
Aparup Das
Page 2 of 5
17:00 – 19:00
19:00 – 20:30
Practical: DNA isolation and PCR amplification of genes in
malaria Parasites/Vectors/Humans, continued….
Dinner
Aparup Das
26 November, 2010 (Friday)
Time
10:00 – 11:00
11:00 – 11:30
11:30 – 12:30
12:30 – 14:30
14:30 – 15:30
15:30 – 16:30
16:30 – 17:00
17:00 – 19:00
19:00 – 20:30
Activities
Lecture: Mapping the dispersal of drug resistance
Tea Break
Lecture: Genetic study of clinical malaria in Senegal and
Thailand: Part I
Lunch and Poster Session
Lecture: Fine structural analysis of growth and differentiation
of successive stages in the life cycle of human malaria
parasites
Lecture: Mosquito vector in India
Tea Break
Practical: Visit to the insect museum in NIMR and identification
of different Anopheles mosquito species
Dinner
Organizer/Speaker
Cally Rooper
Anavaj Sakuntabhai
Nutan Nanda
Bhupinder N. Nagpal
Bhupinder N. Nagpal
27 November, 2010 (Saturday)
Time
10:00 – 19:00
19:00 – 20:30
Activities
Field trip to a nearby village for malaria epidemiological survey
and mosquito collection
Dinner
Organizer
Aparup Das
28 November, 2010 (Sunday)
Time
10:00 – 19:00
Activities
New Delhi city tour
19:00 – 20:30
Dinner
Organizer
Aparup Das
29 November, 2010 (Monday)
Time
10:00 – 11:00
11:00 – 11:30
11:30 – 12:30
12:30 – 14:30
14:30 – 15:30
15:30 – 16:30
Activities
Lecture: Interferon regulated genes, pathogen-specific cell
signaling and immune response
Tea Break
Lecture: Lessons learned from the evolution of malaria
against two major treatment drugs of the 20th century,
chloroquine and amodiaquine
Lunch and Poster Session
Lecture: Genetic study of clinical malaria in Senegal and
Thailand: Part II
Lecture: Antimalarials
Organizer/Speaker
Pramod C. Rath
Thomas E. Wellems
Anavaj Sakuntabhai
Srikanta K. Rath
Page 3 of 5
16:30 – 17:00
17:00 – 18:00
18:00 – 19:00
19:00 – 20:30
Tea Break
Lecture: Species complexes in malaria vectors: Its implication
in malaria control in India
Group Discussion/ Journal Club
Dinner
Nutan Nanda
Aparup Das
30 November, 2010 (Tuesday)
Time
10:00 – 11:00
11:00 – 11:30
11:30 – 12:30
12:30 – 14:30
14:30 – 15:30
15:30 – 16:30
16:30 – 17:00
17:00 – 18:00
18:00 – 19:00
19:00 – 20:30
Activities
Lecture: Human genetic polymorphisms and protection
against severe malaria
Tea Break
Lecture: The kinome of malaria parasites: an untapped source
of potential targets for antimalarial drug discovery
Lunch and Poster Session
Lecture: Population genetics of pharmacogenetic traits
Lecture: Comparative genomics of malaria parasites
Tea Break
Lecture: Toxicity of antimalarials
Group Discussion/ Journal Club
Dinner
Organizer/Speaker
Thomas E. Wellems
Christian Doerig
Estella Poloni
Jane Carlton
Srikanta K. Rath
Aparup Das
1 December, 2010 (Wednesday)
Time
10:00 – 11:00
11:00 – 11:30
11:30 – 12:30
12:30 – 14:30
14:30 – 15:30
15:30 – 16:30
16:30 – 17:00
17:00 – 19:00
19:00 – 20:30
Activities
Lecture: Evolution of human genetic diversity in drugmetabolizing genes: the case of NAT2
Tea Break
Lecture: A glimpse of functional kinomics in Plasmodium
falciparum: investigations into the cellular role of selected
protein kinases
Lunch and Poster Session
Lecture: Molecular diagnostic tools in malaria vector control
Practical: Demonstration on automated DNA sequencing,
sequence editing, alignment and preliminary data analyses
Tea Break
Practical: Demonstration on automated DNA sequencing and
sequence editing, alignment and preliminary data analyses
Dinner
Organizer/Speaker
Estella Poloni
Christian Doerig
Om P. Singh
Aparup Das
Aparup Das
Page 4 of 5
2 December, 2010 (Thursday)
Time
10:00 – 11:00
11:00 – 11:30
11:30 – 12:30
12:30 – 14:30
14:30 – 15:30
15:30 – 16:30
16:30 – 17:00
17:00 – 19:00
19:00 – 20:30
Activities
Lecture: Immune responses to malaria
Tea Break
Lecture: Molecular population genetic studies of Anopheles
minimus, vector of malaria in Thailand
Lunch and Poster Session
Lecture: Characterization of cytochrome oxidase subunit I
(COI) gene of the Anopheles minimus complex and four
related species in the myzomyia series in Vietnam
Lecture: Molecular and evolutionary genetics of malaria:
Indian perspective
Tea Break
Practical: Demonstration of real time PCR
Dinner
Organizer/Speaker
Sukla Biswas
Uraiwan Arunyawat
Ngo Thi Huong
Aparup Das
Anuj Gupta
3 December, 2010 (Friday)
Time
10:00 – 11:00
Activities
Presentations by the participants (10 minutes each)
11:00 – 11:30
Tea Break
11:30 – 12:30
Presentations by the participants, continued…
12:30 – 13:30
Lunch
13:30 – 16:30
Presentations by the participants, continued…
16:30 – 17:00
Tea Break
17:00 – 18:30
Presentations by the participants, continued…
18:30 – 19:00
Awards and closing ceremony
19:00 – 22:30
Gala Dinner
4 December, 2010 (Saturday)
Time
09:00 – 17:30
Activities
Departure of participants and speakers
Page 5 of 5