Chabot College Fall, 2008 Replaced Fall 2011 Course Outline for Biology 2 PRINCIPLES OF CELL/MOLECULAR BIOLOGY AND GENETICS Catalog Description: 2 – Principles of Cell/Molecular Biology and Genetics 5 units Principles of the structure and function of biological molecules, viruses, prokaryotic, and eukaryotic cells with emphasis on homeostasis, cell reproduction and its controls, molecular and transmission genetics, control of gene expression and interactions, genetic control of pattern formation in development, and cell metabolism. Prerequisite: Biology 4 or 6 and Chemistry 1A or equivalent and Mathematics 55 or equivalent (all completed with a grade of “C” or higher). Strongly recommended: eligibility for English 1A . Intended for biological sciences majors. 3 hours lecture, 6 hours laboratory. [Typical contact hours: lecture 52.5, laboratory 105] Prerequisite Skills: Before entering the course the student should be able to: 1. 2. 3. 4. 5. 6. 7. 8. 9. 10. 11. 12. 13. describe the nature of solids, liquids, gases, and phase changes; distinguish between atoms, molecules, compounds, and mixtures; recognize chemical symbols for common elements; write simple chemical formulas and balanced equations including net ionic equations and formulas for oxidation reduction reactions; describe bonding in compounds and ions; describe hybridization, geometry, and polarity for simple molecules; explain chemical and physical changes in terms of thermodynamics; comprehend the basics of pH; collect and analyze scientific data using statistical and graphical methods; use a visible spectrophotometer; identify levels of biological organization ranging from cells to organisms and discuss their interdependencies; describe the general structure of prokaryotic and eukaryotic cells and the process of cell reproduction; explain the principles and mechanisms of evolution and relate them to the systematics of organisms. Expected Outcomes for Students: Upon completion of the course, the student should be able to: 1. 2. 3. 4. 5. 6. apply the principles and philosophies of science; compare and contrast biological molecules and their roles in life processes; compare and contrast structure and function of different types of cells in detail, describe cell reproduction in detail, the cell cycle, and cell communication with emphasis on viruses and prokaryotes; discuss organization, regulation, and transmission of genetic information at the molecular level and analyze patterns and mechanisms of heredity; identify structures of organisms and investigate how they obtain, manipulate, and utilize materials and energy for growth, maintenance, and development; describe the origin of life. Chabot College Course Outline for Biology 2, page 2 Fall 2008 Course Content (Lecture): 1. Scientific research and literature 2. Structure and function of biological molecules 3. Origin and early history of life 4. Cell structure and function 5. Membranes and the movement of materials 6. Cell communication 7. Energy, metabolism, enzymes 8. Cellular respiration 9. Photosynthesis 10. Chemosynthesis 11. Molecular control of cell reproduction and cell cycle 12. Mendelian genetics 13. Molecular genetics 14. Gene interactions 15. Control of gene expression 16. Genetic control of pattern formation in development 17. Gene technology 18. Genomes 19. Viruses Course Content (Laboratory Exercises) : 1. 2. 3. 4. 5. 6. 7. 8. 9. 10. 11. 12. 13. 14. 15. 16. Structure and function of biological molecules Cell structure and function Membranes and movement of materials Cell communication Enzymes Cellular respiration Photosynthesis Molecular control of cell reproduction and cell cycle Mendelian genetics—Drosophila Molecular genetics Gene interactions Control of gene expression Genetic control of pattern formation in development Gene technology Genomes Viruses. Methods of Presentation: 1. 2. 3. 4. Lecture and discussion Observation, collection and analysis of data Laboratory studies Charts, models, slides, specimens Typical Assignments and Methods of Evaluating Student Progress: 1. Typical Assignments a. Laboratory exercise. Identify pigments using chromatography. (compare and contrast biological molecules) b. Worksheets. Solve genetics problems. (analyze patterns and mechanisms of heredity) Chabot College Course Outline for Biology 2, page 3 Fall 2008 c. 2. Internet exercise. Examine karyotypes to identify abnormal chromosome structure and relate to genetic syndromes. (discuss organization of genetic information at the molecular level) Methods of evaluating student progress a. Minimum of two midterm examinations b. Quizzes c. Minimum of two laboratory practicals d. Student projects and laboratory reports e. Final examination Textbook (Typical) Biology , Raven, Johnson, et al, McGraw Hill Publishers, 2007 Special Student Materials: Scientific calculator dih Revised: 11/2007