SIMONE - 1
CURRICULUM VITAE --- JOSEPH V. SIMONE, M.D.
CURRICULUM VITAE UPDATED AUGUST 2014
DATE AND PLACE OF BIRTH: 19 September 1935; Chicago, Illinois
CONTACT: eMail: Simone_J@bellsouth.net
Website: www.SimoneConsulting.com
ACADEMIC DEGREES:
Pre-med
1953-56
M.D.
1956-60
Loyola University, Chicago, Illinois
Stritch School of Medicine, Loyola University, Chicago, Illinois
PROFESSIONAL APPOINTMENTS:
1960-61
Rotating Intern, Presbyterian-St. Luke's Hospital, Chicago, Illinois
1961-63
Resident, Internal Medicine, Presbyterian-St. Luke's Hospital, Chicago, Illinois
1963-66
Fellow, Pediatric Hematology, University of Illinois Research and Educational Hospitals,
Chicago (Chief Resident 1965-66)
1966-67
Instructor in Pediatrics, University of Illinois College of Medicine, Chicago
1967-68
Assistant Member, Department of Hematology, St. Jude Children's Research Hospital,
Memphis, Tennessee
Assistant Professor, Department of Pediatrics, College of Medicine, University of
Tennessee, Memphis
1969-71
Associate Member and Chief of Hematology, St. Jude Children's Research Hospital
Assistant Professor, Department of Pediatrics, College of Medicine, University of
Tennessee
1971-74
Member and Chief of Hematology, St. Jude Children's Research Hospital
Assistant Professor, Department of Pediatrics, College of Medicine,
University of Tennessee
1974-77
Member and Chief of Hematology-Oncology, St. Jude Children's Research Hospital
Associate Professor, Department of Pediatrics, College of Medicine, University of
Tennessee
1977-78
Physician-in-Chief and Director of Pediatric Oncology, Children's Hospital at Stanford,
Palo Alto, California
Professor, Department of Pediatrics, Stanford University School of Medicine
1978-83
Associate Director for Clinical Research, Chief of Hematology-Oncology, St. Jude
Children's Research Hospital
Professor, Department of Pediatrics, College of Medicine, University of
Tennessee
1983-92
Director (CEO), St. Jude Children's Research Hospital
St. Jude Professor of Pediatrics, College of Medicine, University of Tennessee
1992-96
Physician-in-Chief and CEO of Memorial Hospital for Cancer and Allied Diseases,
Attending Pediatrician, Departments of Pediatrics and Medicine and Member, Memorial
Sloan-Kettering Cancer Center and the Sloan-Kettering Institute, New York
1993-96
Professor of Pediatrics, Cornell University Medical College, New York
1993-96
Benno C. Schmidt Chair of Clinical Oncology, Memorial SloanKettering Cancer Center, New York
1996-2001 Jon M. Huntsman Professor of Clinical Oncology, Professor of Pediatrics and Medicine,
University of Utah School of Medicine
1996-2001 Senior Clinical Director, Huntsman Cancer Institute
1996-2001 Executive Director, Huntsman Cancer Care Programs
SIMONE - 2
1998-2000 Director, Utah Cancer Registry, Principal Investigator SEER Program
1997-2001
Assistant Vice-President for Clinical Cancer Programs, University of Utah
1999-2001 Vice-President, Huntsman Cancer Foundation
1999-2000 Interim Chairman, Department of Radiation Oncology, Univ. of Utah
2000-present President, Simone Consulting
2000Clinical Director Emeritus, Huntsman Cancer Institute
2001Professor Emeritus of Pediatrics and Medicine, University of Utah School of Medicine
07/08-12/09 Director Pro tem, University of Florida—Shands Cancer Center
PROFESSIONAL SOCIETY MEMBERSHIPS:
American Society of Hematology, 1970
Fellow, American College of Physicians, 1970
Society for Pediatric Research, 1972
American Association for Cancer Research, 1972
International Society of Experimental Hematology, 1973
Alpha Omega Alpha (Hon.), 1973
Central Society for Clinical Research, 1974
American Pediatric Society, 1975
American Society of Clinical Oncology, 1976
American Academy of Pediatrics, 1981
Fellow, American Association for the Advancement of Science, 1992
Association of American Physicians, 1993
The Harvey Society, 1995
ACTIVE MEDICAL LICENSURE:
Tennessee, Georgia and Florida
CERTIFICATION:
American Board of Pediatrics, January 1, 1967
American Board of Internal Medicine, October 11, 1967
American Board of Pediatric Hematology-Oncology, November 2, 1974
HONORS AND AWARDS:
Healing Arts Award, Memphis Chapter of National Hemophilia Foundation, 1971
Richard and Hinda Rosenthal Foundation Award, the American Assoc. for Cancer Research, 1979
Paul Shonfeld Memorial Visiting Professor, The Children's Memorial Hospital, Chicago, Illinois, 1981
Wadsworth Lecturer, Rush Presbyterian-St. Luke's Medical College, Chicago, Illinois, 1982
Myron Karon Memorial Lecturer, Children's Hospital of Los Angeles,1982
Lecturer, Eighteenth Annual Dr. George Waterman Cancer Dialogue, Rhode Island Hospital, Brown
University, Providence, 1984
Maurice Grimes Lecturer, Canadian Cancer Society, Toronto, 1987
LeRoy Hoeck, M.D. Lecturer and Award of Academic Excellence, Children's National
Medical Center, Washington, D.C., 1993
Ronald McDonald House Charities Award of Excellence, Chicago, 1999
Stritch Medal, Loyola University Chicago, 1999
Distinguished Service Award for Scientific Achievement, American Society of Clinical Oncology, 2002
Public Service Award, American Society of Clinical Oncology, 2006
Apex Award for Publication Excellence, Editorials and Advocacy Writing, Simone’s OncOpinion, 2006
Gold Award for 2006, American Society of Publication Healthcare Editors, Best Regular Column
Contributed, Simone’s OncOpinion in Oncology Times
Distinguished Service Award, Association of American Cancer Institutes, 2008
SIMONE - 3
ASCO-American Cancer Society Award for significant contributions to cancer control or practice, 2010
APEX Award for Excellence in Editorial and Advocacy Writing, 2010
American Society of Healthcare Publication Editors Bronze Award, Best Regular Column, 2010
EXTRAMURAL APPOINTMENTS:
National Cancer Institute
Board of Scientific Counselors, Division of Cancer Treatment, 1976-79
Cancer Clinical Investigation Review Committee, 1978-82 (Chair 1980-82)
Committee Member, US/Italy Exchange Program, 1978-82
Cancer Center Review Committee, 1987-91 (Chair 1989-91)
Cancer Centers Working Group, 1996 (Chair)
Board of Scientific Advisors, 1996-2002
Cancer Centers Working Group, 2002 (Co-Chair)
Institute of Medicine, National Cancer Policy Board, Vice-Chair, 1996-2002; Chairman, 2002-2005
Professional Societies
American Society of Hematology. Sub-Committee on Pediatric Hematology and Oncology, 1976-79
American Board of Pediatrics, Sub-Board of Pediatric Hematology-Oncology, 1977-83 (Chair 1980-82)
Pediatric Oncology Group, Vice Chair, 1981-85 and 1991-92
American Society of Clinical Oncology
Board of Directors, 1979-80; 1985-88
Strategic Planning Committee, 1992-93
Public Issues Committee, 1992-94
Nominating Committee, 1994-96
Task Force on Governance and Structure, 2001-02
Task Force on Pediatric Oncology (Chair), 2001-02
Quality of Care Committee, 2002
Quality Oncology Practice Initiative (Leader) 2003American Association for Cancer Research
Clinical Investigations Program Committee, 1987
Clinical Cancer Research Committee, 1995-98
Public Education Committee, 1995-98
Board of Directors, 1997-2000
Nominating Committee (Chair), 2000-2001
Scientific Retreat on New Frontiers in Cancer Research, 2002
Finance Committee, 2002
Strategic Planning Committee, 2003
Association of American Cancer Institutes
Vice-President, 1991-92
President, 1992-93
Chair, Board of Directors, 1993-94
Nominating Committee, 1994-95
Clinical Research Subcommittee, Ad Hoc Committee on Planning and Issues, 1994-95
National Comprehensive Cancer Network; Medical Director, 1994-96; Chairman,
Board of Directors, 1996-97; Member, Board of Directors, 1994-2005
National Quality Forum, “Cancer Care Quality Measures” Steering Committee, 2002-2003
Cancer Center and Other Advisory Committees
Hemophilia Advisory Committee, State of Tennessee, 1973-77
MACC Fund Scientific Advisory Board, Midwest Children’s Cancer Center,
Milwaukee, 1981-1985
External Advisory Committees
Illinois Cancer Center, 1984-92
SIMONE - 4
The Lombardi Cancer Center at Georgetown University, 1989-91
Cleveland Clinic Cancer Center, 1989
University of Wisconsin, Clinical Cancer Center, 1989-1991, 2005-2012
University of Rochester Cancer Center, 1992-1993
Oregon Cancer Institute, Oregon Health Sciences University, 1992University of Virginia Cancer Center, 1992Fred Hutchinson Cancer Research Center, 1992-2003
President’s Advisory Committee, Fox Chase Cancer Center, 1992University of North Carolina Lineberger Comprehensive Cancer Center, 1993USC/ Norris Comprehensive Cancer Center, 1994Winship Cancer Center, Emory University, 1995
Joint Center for Radiation Therapy, Harvard Medical School, 1995-96
University of Minnesota Cancer Center, 1995-2003
UCLA-Jonsson Comprehensive Cancer Center, 1996-2014
UC-San Diego Cancer Center, 1998University of New Mexico Cancer Center, 2002Hollings Cancer Center, Medical University of S. Carolina, 2002-2004
Massachusetts Institute of Technology Cancer Center, 2003-2013
Foundations
National Hemophilia Foundation, Medical Advisory Board, Memphis, 1970-77
Damon Runyon-Walter Winchell Cancer Fund, Scientific Advisory Comm., 1981-85
Berlex Oncology Foundation, Member, Board of Trustees, 1992-97, 1998-2000
The V Foundation, Member, Board of Directors, 1993-96
Bristol-Myers Squibb Company, Member, Cancer Award Selection Committee, 1989-92, 1993-96
Lustgarten Foundation, Scientific Advisory Committee, Chairman 1998-2005
Cure for Lymphoma Foundation, Scientific Advisory Board, 2001-2003
Huntsman Cancer Foundation, Consultant, 2001-2003
EDITORIAL APPOINTMENTS:
Cancer Treatment Reports, Editorial Advisory Board, 1976-79; 1984-87
Journal of Clinical Oncology, Editorial Board, 1982-83; Associate Editor, 1984-2001
Blood, Editorial Board, 1983-87
Yearbook of Oncology, Associate Editor, 1988-93
Yearbook of Oncology, Editor-in-Chief, 1993-96
Oncology Times, Editorial Board, 1990- ; Columnist, 2003Cancer Research, Associate Editor, 1990-94; 1995-97
SIMONE - 5
Publications
1.
Abildgaard CF, Simone JV, Schulman I. Steroid treatment of hemophilic hematuria. J Pediatr
66:117-119, 1965.
2.
Schulman I, Abildgaard CF, Cornet JA, Simone JV, Currimbhoy Z. Studies of thrombopoiesis. II.
Assay of human plasma thrombopoietic activity. J Pediatr 66:604-612, 1965.
3.
Simone JV, Abildgaard CF, Schulman I. Blood coagulation in thyroid dysfunction. N Engl J Med
273:1057-1061, 1965.
4.
Abildgaard CF, Simone JV, Corrigan JJ, Seeler RA, Edelstein G, Venderheiden J, Schulman I.
Treatment of hemophilia with glycine-precipitated factor VIII. N Engl J Med 275:471-475, 1966.
5.
Abildgaard CF, Simone JV, Schulman I. Factor VIII (anti-haemophilic factor) activity in sickle cell
anemia. Br J Haematol 13:19-27, 1967.
6.
Simone JV, Vanderheiden J, Abildgaard CF. A semi-automatic one-stage factor VIII assay with a
commerically prepared standard. J Lab Clin Med 69:706-712, 1967.
7.
Abildgaard CF, Corrigan JJ, Seeler RA, Simone JV, Schulman I. Meinigococcemia associated
with intravascular coagulation. Pediatrics 40:78-83, 1967.
8.
Abildgaard CF, Simone JV. Thrombopoiesis. Semin Hematol 4:424-452, 1967.
9.
Rishpon-Meyerstein N, Kilbridge T, Simone J, Fried W. The effect of testosterone on
erythropoietin levels in anemic patients. Blood 31:453-460, 1968.
10.
Simone JV, Cornet JA, Abildgaard CF. Acquired von Willebrand's syndrome in systemic lupus
erythematosus. Blood 31:806-812, 1968.
11.
Abildgaard CF, Simone JV, Honig GR, Forman EN, Johnson CA, Seeler RA. von Willebrand's
disease: A comparative study of diagnostic tests. J Pediatr 73:355-363, 1968.
12.
Simone JV. Disseminated intravascular coagulation. Adv Intern Med 15:339-355, 1969.
13.
Pratt CB, Simone JV, Zee P, Aur RJA, Johnson WW. Comparison of daily versus weekly Lasparaginase for the treatment of childhood acute leukemia. J Pediatr 77:474-483, 1970.
14.
Aur RJA, Simone JV, Hustu HO, Walters T, Borella L, Pratt C, Pinkel D. Central nervous system
therapy and combination chemotherapy of childhood lymphocytic leukemia. Blood 37:272-281,
1971.
15.
Aur RJA, Hustu HO, Simone JV, Pratt CB, Pinkel D. Therapy of localized and regional
lymphosarcoma of childhood. Cancer 27:1328-1331, 1971.
16.
Aur RJA, Simone JV, Pratt CB. Successful remission induction in children with acute lymphocytic
leukemia at high risk for treatment failure. Cancer 27:1322-1336, 1971.
17.
Simone JV. Use of fresh blood components during intensive combination therapy of childhood
leukemia. Cancer 28:562-565, 1971.
18.
Pinkel D, Aur RJA, Hustu HO, Simone J. Central nervous system therapy and combination
chemotherapy in childhood lymphocytic leukemia. Proc XIII International Congress of Pediatrics,
Vienna, Austria 14:135-139, 1971.
19.
Simone JV, Hayes WT. Bullous urticaria pigmentosa with bleeding. J Pediatr 78:160-166, 1971.
20.
SIMONE - 6
Choi SI, Simone JV, Journey LJ. Neuraminidase-induced thrombocytopenia in rats. Br J Haematol
22:93-101, 1972.
21.
Aur RJA, Simone JV, Hustu HO, Verzosa MS. A comparative study of central nervous system
irradiation and intensive chemotherapy early in remission of childhood acute lymphocytic leukemia.
Cancer 29:381-391, 1972.
22.
Walters TR, Bushore M, Simone JV. Poor prognosis in Negro children with acute lymphocytic
leukemia. Cancer 29:210-214, 1972.
23.
Pinkel D, Simone J, Hustu HO, Aur RJA. Nine years experience with "total therapy" of childhood acute
lymphocytic leukemia. Pediatrics 50:246-251, 1972.
24.
Simone J, Holland E, Johnson W. Fatalities during remission of childhood leukemia. Blood 39:759770, 1972.
25.
Simone JV. Treatment of children with acute lymphocytic leukemia. Adv Pediatr 19:13-45, 1972.
26.
Aur RJA, Verzosa MS, Hustu HO, Simone JV. Response to combination therapy after relapse in
childhood acute lymphocytic leukemia. Cancer 30:334-338, 1972.
27.
Simone JV, Aur RJA, Hustu HO, Pinkel D. "Total therapy" studies of acute lymphocytic leukemia in
children. Current results and prospects for cure. Cancer 30:1488-1494, 1972.
28.
Simone J, Pinkel D. Rationale and results of combination chemotherapy and central nervous system
irradiation in acute lymphocytic leukemia. In: Dutcher RM, ed. Unifying concepts of leukemia
[Proceedings of the International Symposium on Comparative Leukemia Research, 5th Padova-Venice,
1971]. Bibliotheca Haematologica No. 39. Basel: S Karger, pp 1068-1073, 1973.
29.
Aur RJA, Hustu HO, Verzosa MS, Wood A, Simone JV. Comparison of two methods of preventing
central nervous system leukemia. Blood 42:349-357, 1973.
30.
Borella L, Green A, Aur RJA, Simone JV, Pinkel D. Clinical and immunological recovery of children
with acute lymphocytic leukemia admitted to "total therapy" studies. Recent Results Cancer Res
43:145-50, 1973.
31.
Aur RJA, Hustu HO, Verzosa MS, Simone JV, Pinkel D. Results of ten years of combination central
nervous system radiotherapy and multiple chemotherapy in childhood acute lymphocytic leukemia (In
Spanish). Sangre 18:449-454, 1973.
32.
Choi SI, Simone JV. Platelet production in experimental iron deficiency anemia. Blood 42:219-228,
1973.
33.
Hustu HO, Aur RJA, Verzosa MS, Simone JV, Pinkel D. Prevention of central nervous system
leukemia by irradiation. Cancer 32:585-597, 1973.
34.
Simone JV. Preventive central nervous system therapy in acute leukemia (Editorial). N Engl J Med
289:1248-1249, 1973.
35.
Aur RJA, Verzosa MS, Hustu HO, Simone JV. A comparative study of multiple schedules of
maintenance chemotherapy in childhood lymphocytic leukemia (In Portuguese). Rev Assoc Med Bras
20:185-188, 1974.
36.
Choi SI, Simone JV, Jackson CW. Megakaryocytopoiesis in experimental iron deficiency anemia.
Blood 43:111-120, 1974.
37.
Simone JV. Acute lymphocytic leukemia in childhood. Semin Hematol 11:25-39, 1974.
SIMONE - 7
38.
Fleming I, Simone JV, Jackson R, Johnson WW, Walters T, Mason C. Splenectomy and
chemotherapy in acute myelocytic leukemia of childhood. Cancer 33:427-434, 1974.
39.
Simone JV. Management of childhood leukemia. Postgrad Med 55:225-231, 1974.
40.
Jackson CW, Simone JV, Edwards CC. The relationship of anemia and thrombocytosis. J Lab Clin
Med 84:357-368, 1974.
41.
Choi S, Simone JV, Edwards CC. Effects of vincristine on platelet production. In: Baldini MG, Ebbe S,
eds. Platelets: Production, function, transfusion and storage. New York: Grune & Stratton, pp 51-61,
1974.
42.
Aur RJA, Simone JV, Pinkel D, Hustu HO, Verzosa MS. Recent changes in the prognosis of childhood
acute lymphocytic leukemia. Proceedings of the XIVth International Congress of Pediatrics, Buenos
Aires, Argentina, Vol 9, pp 48-66, 1974.
43.
Simone JV. Childhood leukemia: The changing prognosis. Hosp Pract 9:59-68, 1974.
44.
Aur RJA, Simone JV, Hustu HO, Verzosa M, Pinkel D. Cessation of therapy during complete remission
of childhood acute lymphocytic leukemia. N Engl J Med 291:1230-1234, 1974.
45.
Simone JV, Aur RJA, Hustu HO, Verzosa M, Pinkel D. Combined modality therapy of acute
lymphocytic leukemia. Cancer 35:25-35, 1975.
46.
Simone JV. Prognostic factors in childhood acute lymphocytic leukemia. Adv Biosci 14:27-42, 1975.
47.
Lawrence HJ, Simone JV, Aur RJA. Cyclophosphamide-induced hemorrhagic cystitis in children with
leukemia. Cancer 36:1572-1576, 1975.
48.
Aur RJA, Simone JV, Pinkel D, Hustu HO, Verzosa M. Current status of total therapy of childhood
acute lymphocytic leukemia (In Spanish). Hematologia-Mexico 5:35-49, 1975.
49.
Hughes WT, Feldman S, Aur RJA, Verzosa MS, Hustu HO, Simone JV. Intensity of
immunosuppressive therapy and the incidence of Pneumocystis carinii pneumonitis. Cancer 36:20042009, 1975.
50.
Simone JV, Aur RJA, Hustu HO, Verzosa M. Acute lymphocytic leukemia in children. Cancer 36:770774, 1975.
51.
Simone JV, Verzosa MS, Rudy JA. Initial features and prognosis in 363 children with acute lymphocytic
leukemia. Cancer 36:2099-2108, 1975.
52.
Verzosa MS, Aur RJA, Simone JV, Hustu HO, Pinkel D. Five years after central nervous system
irradiation of children with leukemia. Int J Radiat Oncol Biol Phys 1:209-215, 1976.
53.
Simone JV. Factors that influence haematological remission duration in acute lymphocytic leukaemia.
Br J Haematol 32:465-472, 1976.
54.
Mauer AM, Simone JV. The current status of the treatment of childhood acute lymphoblastic leukemia.
Cancer Treat Rev 3:17-41, 1976.
55.
Choi S, Simone JV. Acute nonlymphocytic leukemia in 171 children. Med Pediatr Oncol 2:119-146,
1976.
56.
Evans WE, Barker LF, Simone JV. Double-blind evaluation of 5-um final filtration to reduce
postinfusion phlebitis. Am J Hosp Pharm 33:1160-1163, 1976.
57.
Pinkel D, Hustu HO, Aur RJA, Smith K, Borella LD, Simone JV. Radiotherapy in leukemia and
lymphoma of children. Cancer 39:817-824, 1977.
58.
SIMONE - 8
Dow LW, Borella L, Sen L, Aur RJA, George SL, Mauer AM, Simone JV. Initial prognostic features and
lymphoblast-erythrocyte rosette formation in 109 children with acute lymphoblastic leukemia. Blood
50:671-682, 1977.
59.
Mauer AM, Simone JV, Pratt CB. Current progress in the treatment of the child with cancer. J Pediatr
91:525-539, 1977.
60.
Murphy SB, Aur RJA, Simone JV, George SL, Mauer AM. Pretreatment cytokinetic studies in 94
children with acute leukemia. Relationship to other variables at diagnosis and to outcome of standard
treatment. Blood 49:683-691, 1977.
61.
Simone JV, Aur RJA, Hustu HO, Verzosa M. Trends in the treatment of childhood leukemia. In: Neth
R, Gallo RC, Mannweiler K, Moloney WC, eds. Hämatologie und bluttransfusion. Modern trends in
human leukemia II. Munich: JF Lehmanns, pp 263-269, 1977.
62.
Thompson E, Simone JV. Blood transfusion in children with cancer. J Sch Health 47:154-157, 1977.
63.
Simone JV, ed. Acute Leukemia. Clinics in haematology. Vol 7. Philadelphia: WB Saunders, 1978.
64.
Aur RJA, Simone JV, Verzosa MS, Hustu HO, Barker L, Pinkel DP, Rivera GK, Dahl GV, Wood A,
Stagner S, Mason C. Childhood acute lymphocytic leukemia: Study VIII. Cancer 42:2123-2134, 1978.
65.
Simone JV, Aur RJA, Hustu HO, Verzosa MS, Pinkel D. Three to ten years after cessation of therapy
in children with leukemia. Cancer 42:839-844, 1978.
66.
Dahl GV, Simone JV, Hustu HO, Mason C. Preventive central nervous system irradiation in children
with acute nonlymphocytic leukemia. Cancer 42:2187-2192, 1978.
67.
Aur RJA, Simone JV, Verzosa MS, Hustu HO, Pinkel DP, Barker LF. Leuko-encephalopathy in children
with acute lymphocytic leukemia receiving preventive central nervous system therapy. Sangre 23:1-12,
1978.
68.
George SL, Aur RJA, Mauer AM, Simone JV. A reappraisal of the results of stopping therapy in
childhood leukemia. N Engl J Med 300:269-274, 1979.
69.
Simone JV, Aur RJA, Hustu HO, Verzosa MS. Treatment of acute lymphocytic leukemia (ALL) in
children. In: Mandelli F, ed. Therapy of acute leukemias [Proceedings of the 2nd International
Symposium, Rome, 1977]. Rome: Lombardo Editore, pp 319-325, 1979.
70.
Simone JV. Childhood acute lymphocytic leukemia: A model for therapeutic strategies in hemopoietic
neoplasia. Recent Results Cancer Res 69:49-54, 1979.
71.
Simone JV. Leukemia. In: Proceedings of the national conference on the care of the child with
cancer. American Cancer Society Professional Educational Publication, pp 50-55, 1979.
72.
Simone JV. Childhood leukemia as a model for cancer research: The Richard and Hinda Rosenthal
Foundation Award Lecture. Cancer Res 39:4301-4307, 1979.
73.
Simone JV, Hustu HO, Aur RJA. Prevention and treatment of central nervous system leukaemia in
childhood. [Monograph of the International Symposium on the CNS Complications of Malignant
Diseases, Southampton, England]. In: Whitehouse JMA, Kay HEM, eds. Central nervous system
complications of malignant diseases. London: McMillan Press, pp 19-35, 1979.
74.
Simone JV. The treatment of acute lymphoblastic leukemia. Br J Haematol 45:1-4, 1980.
75.
Ch'ien LT, Aur RJA, Stagner S, Cavallo K, Wood A, Goff J, Pitner S, Hustu HO, Seifert MJ, Simone JV.
Long-term neurological implications of somnolence syndrome in children with acute lymphocytic
leukemia. Ann Neurol 8:273-277, 1980.
76.
SIMONE - 9
Simone JV. Outlook for acute lymphocytic leukemia in children in 1982. Ann Rev Med 32:207-212,
1981.
77.
Ch'ien LT, Aur RJA, Verzosa MS, Coburn TP, Goff JR, Hustu HO, Price RA, Seifert MJ, Simone JV.
Progression of methotrexate-induced leuko-encephalopathy in children with leukemia. Med Pediatr
Oncol 9:133-141, 1981.
78.
Bowman WP, Simone JV. Acute leukemia in children. In: Fries JF, Erlich GE, eds. Prognosis,
contemporary outcomes of disease. Bowie, Maryland: Charles Press, pp 149-152, 1981.
79.
Simone JV. Principles of pediatric oncology. In: Carter SK, Glatstein E, Livingston RB, eds.
Principles of cancer treatment. New York: McGraw Hill, pp 153-161, 1981.
80.
Simone JV. Optimal current treatment of childhood acute lymphoblastic leukemia. Cancer Treat Rep
65:97-100, 1981.
81.
Simone JV, Cassady JR, Filler RM. Cancers in childhood. In: DeVita VT Jr, Hellman S, Rosenberg
SR, eds. Cancer, principles and practice of oncology. Philadelphia: JB Lippincott, pp 1254-1330,
1982.
82.
Simone JV. Late complications of treatment of children with leukemia and lymphoma. In: Rosenberg
SA, Kaplan HS, eds. Malignant lymphomas. New York: Academic Press, pp 663-673, 1982.
83.
Rivera GK, Dahl GV, Murphy SB, Bowman WP, Aur RJ, Avery TL, Simone JV. VM26 therapy in
children with drug-refractory lymphocytic leukemia. Cancer Chemother Pharmacol 7:169-172, 1982.
84.
Simone JV. The present situation in treatment and prognosis of childhood acute lymphocytic leukemia
with an outlook for the future. Haematologica 67:329-334, 1982.
85.
Dahl GV, Kalwinsky DK, Murphy SB, Look AT, Amadori S, Kumar M, Novak R, George SL, Mason C,
Mauer AA, Simone JV. Cytokinetically based induction chemotherapy and splenectomy for childhood
acute nonlymphocytic leukemia. Blood 60:856-863, 1982.
86.
Murphy SB, Dahl GV, George SL, Karas J, Look AT, Simone JV, Mauer AA. Determination of the
significance of in vitro blast cell (3H)thymidine labelling indices obtained initially and serially during
induction therapy of acute nonlymphocytic leukemia. Leuk Res 6:639-648, 1982.
87.
Bowman WP, Ochs J, Pui C-H, Kalwinsky DK, Abromowitch M, Aur RJA, Rivera GK, Simone JV. New
directions of St. Jude total-therapy protocols: Study X for standard-risk childhood acute lymphoblastic
leukemia. In: Murphy SB, Gilbert JR, eds. Leukemia research: Advances in cell biology and
treatment. New York: Elsevier Science, pp 203-211, 1983.
88.
Rivera GK, Dahl GV, Murphy SB, Bowman WP, Abromowitch M, Ochs J, Pui C-H, Kalwinsky DK, Avery
TL, George SL, Simone JV. The epipodophyllotoxin VM-26 in treatment of high-risk acute
lymphoblastic leukemia: Rationale and early results. In: Murphy SB, Gilbert JR, eds. Leukemia
research: Advances of cell biology and treatment. New York: Elsevier Science, pp 213-220, 1983.
89.
Simone JV. Drug treatment for acute childhood leukemia. Drug Therapy 8:25-34, 1983.
90.
Pui C-H, Jackson CW, Chesney C, Lyles SA, Bowman WP, Abromowitch M, Simone JV. Sequential
changes in platelet function and coagulation in leukemic children treated with L-asparaginase,
prednisone, and vincristine. J Clin Oncol 1:380-385, 1983.
91.
Rivera GK, George SL, Bowman WP, Kalwinsky DK, Dahl GV, Hustu HO, Simone JV. Second central
nervous system prophylaxis in children with acute lymphoblastic leukemia who relapse after elective
cessation of therapy. J Clin Oncol 1:471-476, 1983.
92.
SIMONE - 10
Bowman WP, Presbury G, Melvin SL, George SL, Simone JV. A comparative analysis of acute
lymphocytic leukemia in white and black children: Presenting clinical features and immunologic
markers. In: Magrath IT, O'Conor GT, and Ramot B, eds. Pathogenesis of leukemias and lymphomas:
Environmental influences. New York: Raven Press, pp 169-177, 1984.
93.
Simone JV. Treatment of meningeal leukemia (Editorial). J Clin Oncol 2:357-358, 1984.
94.
Simone JV. Neuroblastoma (Editorial). J Clin Oncol 2:717-718, 1984.
95.
Simone JV, Rivera GK. Management of acute leukemia. In: Sutow WW, Fernbach DS, and Vietti TS,
eds. Clinical pediatric oncology. St. Louis: CV Mosby, pp 378-402, 1984.
96.
Ochs J, Bowman WP, Pui C-H, Abromowitch M, Mason C, Simone JV. Seizures in childhood
lymphoblastic leukaemia patients. Lancet 2: 1422-1424, 1984.
97.
Simone JV, Rivera GK. Clinical trials in childhood acute lymphocytic leukemia. In: Veronesi V,
Bonadonna G, eds. Clinical trials in cancer medicine. New York: Academic Press, pp 501-508, 1985.
98.
George SL, Ochs J, Mauer AM, Simone JV. The importance of an isolated central nervous system
relapse in children with acute lymphoblastic leukemia. J Clin Oncol 3:776-781, 1985.
99.
Ochs J, Rivera GK, Aur RJA, Hustu HO, Berg R, Simone JV. Central nervous system morbidity
following an initial isolated central nervous system relapse and its subsequent therapy in childhood
acute lymphoblastic leukemia. J Clin Oncol 3:622-626, 1985.
100. Kalwinsky DK, Rivera GK, Dahl GV, Roberson P, George SL, Murphy SB, Simone JV. Variation by
race in presenting clinical and biologic features of childhood acute lymphoblastic leukemia:
Implications for treatment outcome. Leuk Res 6:817-823, 1985.
101. Murphy SB, Dahl GV, Look AT, Ochs J, Abromowitch M, Pui C-H, Bowman WP, Simone JV, Kalwinsky
DK, Evans WE, George SL, Mirro J, Williams D, Dow LW, Rivera GK. Recent results from total
therapy study X for standard and high risk acute lymphoblastic leukemia in children: Recognition of
new clinical and biologic risk features. In: Neth G, Greaves J. Hämatologie und bluttransfusion. Vol
29. Modern trends in human leukemia. Munich: JF Lehmanns, pp 78-81, 1985.
102. Pui C-H, Dahl GV, Kalwinsky DK, Look AT, Mirro J, Dodge RK, Simone JV. Central nervous system
leukemia in children with acute nonlymphoblastic leukemia. Blood 66:1062-1067, 1985.
103. Link MP, Goorin AM, Angela WM, Green AA, Pratt CB, Belasco JB, Pritchard J, Malpas JS, Baker AR,
Kirkpatrick JA, Ayala AG, Shuster JJ, Abelson HT, Simone JV, Vietti TJ. The effect of adjuvant
chemotherapy on relapse-free survival in patients with osteosarcoma of the extremity. N Engl J Med
314:1600-1606, 1986.
104. Look AT, Williams DL, Simone JV. Relationships of cell biology to therapy in childhood leukemia. In:
Cory JG, Szentivanyi A, eds. Cancer biology in therapeutics. New York: Plenum Press, pp 161-171,
1986.
105. Simone JV. Pediatric oncology. In: Rudolph AM, ed. Pediatrics. 18th Ed. Norwalk, Connecticut:
Appleton and Lange, pp 1093-1096, 1987.
106. Simone JV. Acute lymphocytic leukemia in children: Achievements and perspectives. Tijdschr
Kindergeneeskd 56:107-108, 1988.
107. Rivera GK, Raimondi SC, Hancock ML, Behm FG, Pui C-H, Abromowitch M, Mirro J, Ochs JS, Look
AT, Williams, DL, Murphy SB, Dahl GV, Kalwinsky DK, Evans WE, Kun L, Simone JV, Crist WM.
Improved outcome in childhood acute lymphoblastic leukemia with reinforced early treatment and
rotational combination chemotherapy. Lancet 337:61-69, 1991.
SIMONE - 11
108. Ochs J, Mulhern R, Fairclough D, Parvey L, Whitaker J, Ch'ien L, Mauer A, Simone J. Comparison of
neuropsychologic functioning and clinical indicators of neurotoxicity in long-term survivors of childhood
leukemia given cranial radiation or parenteral methotrexate: A prospective study. J Clin Oncol 9:145151, 1991.
109. Carter MC, Thompson EI, Simone JV. The survivors of childhood solid tumors. Pediatric Clinics of
North America. 38:505-526, 1991.
110. Simone JV, Rivera GK, Look AT, Crist WM. Therapy of childhood leukemia: understanding success
and failure. Proceeding of the Second International Symposium on Children's Cancer, Tokyo, Japan,
1989. Kluver Academic Publishers, pp. 129-134, 1991.
111. Pui C-H, Dodge RK, Look AT, George SL, Rivera GK, Abromowitch M, Ochs J, Evans WE, Crist WM,
Simone JV. Risk of adverse events in children completing treatment for acute lymphoblastic leukemia:
St. Jude total therapy studies VIII, IX and X. J Clin Oncol 9:1341-1347, 1991.
112. Pui C-H, Simone JV, Hancock ML, Evans WE, Williams DL, Bowman WP, Dahl GV, Dodge RK, Ochs
J, Abromowitch M, Rivera GK. Impact of three methods of treatment intensification on acute
lymphoblastic leukemia in children: long-term results of St. Jude total therapy study X. Leukemia
6:150-157, 1992.
113. Simone JV. Autologous bone marrow transplantation in childhood cancer (Editorial). J Clin Oncol
11:1439-1440, 1993.
114. Rivera GK, Pinkel D, Simone JV, Hancock ML, Crist WM. Treatment of Acute Lymphoblastic
Leukemia - 30 Years' Experience at St. Jude Children's Research Hospital, N Engl J Med 319:12891295, 1993.
115. Simone JV. Cancer Treatments: Today and Tomorrow. Forum for Applied Research and Public Policy,
10:35-37, 1995.
116. Simone JV, Ed. Pediatric oncology. In: Rudolph AM, ed. Pediatrics. 20th Ed. Stamford, CT, Appleton
and Lange, pp 1265-1306, 1996.
117. Simone JV. Introduction to oncology. In: Cecil Textbook of Medicine. 20th Ed. Philadelphia, PA,
Saunders, pp 1004-1008, 1996.
118. Steinherz P, Simone JV. Biology of childhood cancer. In: Holland J, ed. Psycho-oncology. New York,
Oxford University Press, pp 881-896, 1998.
119. Simone JV, Lyons J. The evolution of cancer care for children and adults. (Editorial) J Clin Oncol
16:2904-2905, 1998.
120. Simone JV, Lyons, J. Superior cancer survival in children compared to adults: A superior system of
cancer care? Background paper, National Cancer Policy Board, Institute of Medicine, 1998.
www2.nas.edu/cancerbd/
121. Hewitt M, Simone JV, Eds. Ensuring quality cancer care. A report of the National Cancer Policy Board
of the Institute of Medicine. Washington, DC, National Academy Press, 1999.
122. Simone JV. Understanding academic medical centers: Simone’s maxims. Clin Can Res 5: 2281-2285,
1999.
123. Simone JV. Introduction to oncology. In: Cecil Textbook of Medicine. 21st Ed. Philadelphia, PA,
Saunders, pp 1029-1032, 2000.
124. Simone JV. (Guest Ed.) Classic Papers and Current Comments: Pediatric Cancer. 5:1-201, 2000
SIMONE - 12
125. Hewitt M, Simone JV, Eds. Enhancing data systems to improve the quality of cancer care. A report of
the National Cancer Policy Board of the Institute of Medicine. Washington, DC, National Academy
Press, 2000.
126. Simone JV. Understanding cancer centers. J Clin Onc 20:4503-4507, 2002.
127. Simone JV. A history of St. Jude Children’s Research Hospital. Brit J Haem 120: 549-555, 2003.
128. Hewitt M, Weiner S, Simone JV, Eds. Childhood Cancer Survivorship: Improving care and quality of
life. A report of the National Cancer Policy Board of the Institute of Medicine. Washington, DC, National
Academy Press, 2003.
129. Simone JV. Childhood leukemia – successes and challenges for survivors. New Eng J Med 349: 627628, 2003.
130. Simone JV: “Institutions Don’t Love You Back – And other maxims for navigating organizations.”
Atlanta, Georgia, Simone Consulting Company, 2004.
131. Adamson PC, Weiner S, Simone JV, Gelband H, Eds. Making Better Drugs for Children with Cancer. A
report of the National Cancer Policy Board of the Institute of Medicine. Washington, DC, National
Academy Press, 2005
132. Eden J, Simone JV, Eds. Assessing the Quality of Cancer Care: An Approach to Measurement in
Georgia. A report of the National Cancer Policy Board of the Institute of Medicine. Washington, DC,
National Academy Press, 2005
133. Neuss MN, Desch CE, McNiff KK, Eisenberg PD, Gesme DH, Jacobson JO, Jahanzeb M, Padberg JJ,
Rainey JH, Guo JJ, Simone JV: A process for measuring the quality of cancer care: The Quality
Oncology Practice Initiative. J Clin Oncology 23:6233-6239, 2005
134. Simone JV: History of the treatment of childhood ALL: A paradigm for cancer care. Best Pract Res Clin
Haem 19:353-359, 2006
135. Herdman R, McGuire W, Simone J: Influencing cancer policy. Health Affairs 25: 800-807, 2006
136. Simone JV: Sustaining the Dignity and Nobility of Medical Care. Editorial Rx Press, Orange Park, FL,
2007 (further information at www.editorialrxpress.com)
137. Jacobson JO, Neuss MN, McNiff KM, Kadlubek P, Thacker LR, Song F, Eisenberg P, Simone JV:
Improvement in oncology practice performance through voluntary participation in the Quality Oncology
Practice Initiative. J Clin Onc 26: 1893-1898, 2008.
138. McNiff KK, Neuss MN, Jacobson JO, Eisenberg PD, Kabudlek P, Simone JV. Measuring supportive
care in medical oncology practice: Lessons learned from the Quality Oncology Practice Initiative. J Clin
Onc 26: 3832-3837, 2008
139. Simone JV. Origins of the Quality Oncology Practice Initiative. J Onc Pract 5: 1-2, 2009
140. Neuss MN, Jacobson JO, McNiff KK, Kadlubek P, Eisenberg PD, Simone JV. Evolution and elements
of the Quality Oncology Practice Initiative measure set. Cancer Control 16: 312-317, 2009
141. Simone’s Maxims Updated and Expanded: Understanding Today’s Academic Medical Centers. 2012,
EditorialRxPress.com.
142. Neuss MN, Malin JL, Chan S, Kadlubek PJ, Adams JL, Jacobson, JO, Blayney DW, Simone JV.
Measuring the improving quality of outpatient care in medical oncology practices in the United States. J
Clin Onc 31: 1-7, 2013
SIMONE - 13
143. Hudson MM, Link MP, Simone JV. Milestones in the curability of pediatric cancers. j Clin Onc 32: 23912397, 2014
Updated September, 2014