TCES
SPRING MEETING
14-15 JUNE, 2004
PROGRAMME
Hosted by
TCES – SPRING MEETING 14-15 JUNE 2004
TCES Spring Conference 14th & 15th June 2004
School of Medicine, Keele University
Programme
Monday 14th June
12.00 – 1.00 Registration (venue – Medical School atrium, Keele University
Campus)
1.00 – 1.10 Welcome – Professor Alicia El Haj (TCES President) (venue – ground
floor lecture theatre, Medical School)
1.10 – 2.00 Plenary Lecture – Professor James Richardson (Robert Jones and
Agnes Hunt Orthopaedic Hospital, University of Keele)
Session 1a: Tissue and Cell Engineering
Session Chair: Dr Sarah Cartmell
2.00 – 2.15 T. Sun (University of Sheffield)
Self-organisation of Skin Cells in an Electrospun Tissue Engineered Scaffold
2.15 – 2.30 Anthony Metcalfe (University of Manchester)
Understanding Regenerative Medicine Mechanisms for Future Applications in Skin
Tissue Engineering
2.30 – 2.45 R. Hill (University of Sheffield)
Alpha-Melanocyte Stimulating Hormone Anti-imflammatory Action in Human
Dermal Fibroblast Cells: Application in Skin Tissue Engineering
2.45 – 3.00 A.Mantalaris (Imperial College)
Mesodermal Cell Development from Embryonic Stem Cells using HepG2
Conditioned Medium
3.00 – 3.25 Break (venue – Medical School atrium)
Session 1b: Tissue and Cell Engineering
Session Chair: Dr Ying Yang
3.25 – 3.40 Rick Knight (University of Leeds)
Development of Methods for Tissue Engineering a Cardiac Valve using
Mesenchymal Stem Cells
3.40 – 3.55 Patrick Ginty (University of Nottingham)
The supercritical processing of mammalian cells: a new route to seeding tissue
engineering constructs
3.55 – 4.10 Laura Haughton (Cardiff School of Biosciences)
The effects of Notch signal modulation on wounded articular cartilage
4.10 – 4.25 Steven Hughes (University of Keele)
Magnetic particle mediated activation of the mechanosensitive ion channel TREK-1
TCES – SPRING MEETING 14-15 JUNE 2004
4.25 – 4.40 Osian Meredith (Davos/University of Glasgow)
Cell proliferation and structure is defined by specific metal microtopography
4.40 – 5.20 Break (venue – rooms 1.35/1.36, Medical School)
5.20 – 6.30 Poster Session
(Posters 1-14; Poster Session Chair: Professor Kevin Shakesheff) (venue – rooms
1.35/1.36, Medical School)
7.30 Conference Dinner (venue – Hawthorns restraunt)
Tuesday 15th June
Session 2 Biomaterial Scaffold Technology
Session Chair: Dr Felicity Rose
9.00 –9.15 Mairead Wood (University of Keele)
Enhancing Osteoblast Mechanotransduction for Bone Tissue Engineering
Applications
9.15 – 9.30 Mark Ahearne (University of Keele)
Gene expressions from osteoblasts cultured on poly--caprolactone based
biodegradable biomaterials
9.30 – 9.45 Marianne Ellis (University of Bath)
Biodegradable Hollow Fibre Membranes for Clinical Scale Bone Tissue Constructs
9.45 – 10.00 Duce Gotora (University of Oxford)
Mineralisation and cross-linking techniques to improve the mechanical properties
of collagen-calcium phosphate (Coll-CaP) composites to be used as bone
analogues
10.00 – 10.15 Joanne Ingram (University of Leeds)
Development of an acellular scaffold capable of recellularisation for use in tissue
engineering of the ACL
10.15 – 10.30 Stacy-Paul Wilshaw (University of Leeds)
Production of an acellular amniotic membrane for use in tissue engineering
10.30 - 11.00 Break (venue – Medical School atrium)
Session 3 Monitoring and Assessment
Session Chair: Dr Vivek Mudura
11.00 – 11.15 Lisa Worrall (University of Nottingham)
Real Time Monitoring of a 3D Cancer Model in the RCCSTM
11.15 – 11.30 Mary Morgan (University College London)
Elastic scattering spectroscopy: a novel technique to monitor tendon structure in
situ
TCES – SPRING MEETING 14-15 JUNE 2004
11.30 – 11.45 M. Oates (University of Liverpool)
A Method to Quantify Angiogenesis within Scaffolds
11.45 – 12.00 Delphine Pellenc (Universite de Cergy-Pontoise, France)
Adsorption-induced protein network formation:
in situ characterisation and numerical simulation of Fibronectin assembly on
hydroxyapatite
12.00 – 2.00 Poster Session and Lunch (Posters 15 – 26; Poster Session Chair: Dr
Stuart McBain) (venue – rooms 1.35/1.36, Medical School)
TCES – SPRING MEETING 14-15 JUNE 2004
Posters
1) C. Gaissmaier (University of Eberhard-Karls, Germany)
Investigation of Human Platelet Supernatant on Proliferation and Matrix Synthesis
of Human Articular Chondrocytes in Monolayer (2D) and Three-Dimensional (3D)
Alginate Cultures
2) Heikki Penttilä (University of Tampere/Oulu, Finland)
Study of use of Surface Sensor Pulse oximeter in follow-Up of Free Flaps
3) Karen Hampson (University of Keele)
The effects of a 3D environment on the osteogenic differentiation of mesenchymal
cells
4) S. E. W. Grubb (University of Sheffield)
Anti-inflammatory peptide material approaches to preventing coronary heart
disease
5) Elbert Baas (University of Keele)
Development of a ‘Mechano-Active’ Scaffold for Skeletal Tissue Engineering
6) Thomas Wright (UCL)
The “Blanch-Blush Reaction” (BBR):
Non-invasive optical techniques for monitoring connective tissue organisation.
7) G. Kelsall (University of Sheffield)
Establishment of Tenocyte Spheroid Cultures
8) Nanette Scutt (University of Sheffield)
The Effect Of Dexamethasone On Tendon Derived Cells
9) Stuart McBain (University of Keele)
Activation of Human Jejunal alpha1C Calcium Channel Subunit using targeted
Magnetic Nanoparticles
10) Gordana Sofija Djerkovic (UCL)
Inhibitory effects of soluble fibronectin fractions on cultured neurones.
11) Kirsty Richardson (Cardiff University)
Genotyping chondrocytes in the superficial zone of articular cartilage
12) Stephen Richardson (University of Manchester)
Evaluation of Methods for Human Bone Marrow Mesenchymal Stromal Cell
Differentiation into Nucleus Pulposus Cells for use in Tissue Engineering of the
Human Intervertebral Disc.
13) D. Giannaras (University of Glasgow)
Effects of Nano-topography on Fibroblast Endocytosis
TCES – SPRING MEETING 14-15 JUNE 2004
14) W. Szymczyk (University of Glasgow)
Measurement of Displacements Applied by Fibroblasts on Flexible Surfaces with
Regular Nanopattern
15) Alice Beare (University of Manchester)
In vivo Response to Porous Poly (-caprolactone) Materials
16) Heikki Penttilä (Helsinki University Central Hospital, Finland)
Construction of Cartilage Using Prefabricated Microvascularied Perichondrial
Bioabsorbable Polyactide Nonwoven Scaffolds
17) Eero Waris (University of Helsinki, Finland)
Novel Bioabsorbable Interposition Arthroplasty of Small Joints in an Experimental
Minipig Model
18) L. Smith (University of Sheffield)
Amphiphilic Networks for Dermal Matrix Hybrids for Skin Reconstruction
19) Nureddin Ashammakhi (University of Tampere/Oulu, Finland)
Novel Multifunctional Materials (MFM): Bioabsorbable Osteoconductive DrugReleasing Hard Tissue Fixation Screws
20) Elizabeth Pearson (University of Nottingham)
Control of Chondrocyte Attachment to a Physically Modified 3D Polymer Scaffold
21) Jill T. Callaghan (University of Liverpool)
The In-Vitro Evaluation of PCL / PLGA Copolymers as - Potential Bone
Replacement Materials.
22) Nureddin Ashammakhi (University of Tampere/Oulu, Finland)
Evaluation of Pol-L/D-Lactide (PLDLA) 96/4 Scaffolds Implanted in the Subcutis of
Rats
23) Sue Felton (University of Leeds)
Self-Assembling Fibrillar Networks as Smart Scaffolds for Tissue Engineering
24) Tri Suciati (University of Nottingham)
Development of Microparticle Based Scaffolds For Tissue Engineering
25) Saeed Mirsadraee (University of Leeds)
Tissue Engineering of Human Pricardium: Characteristics of an SDS Decellularised
Matrix
26) Matthew Leach (University of Sheffield)
The Fibroblastic-Colony Forming Unit Assay In Tendon Research
TCES – SPRING MEETING 14-15 JUNE 2004