Application for Maryland Biotechnology Center Translational Research Awards Purpose: Maryland is globally recognized as one of the largest clusters of research intensity in the life sciences across its academic, federal and industry sectors. The Maryland Biotechnology Center seeks to catalyze the “translation” of this early stage bioscience research into commercially viable products or services. Identification of research that lends itself to commercial applicability and providing critical “proof of concept” funding is critical to this effort. Also critical is leveraging discoveries across sectors and disciplines in a collaborative environment. This award program favors projects that involve interactions between the State’s academic research programs and those in private companies that provide a clear path to move promising research on a viable commercialization path. The Award: The award minimum may not exceed $200,000 per awardee per annual award cycle. Funds will be released in project phases tied to successful completion of identified milestones. Companies must apply 100% of project costs financed by the award to direct costs for tasks associated with the milestones. The project should be able to achieve all indicated milestones within one year. The award is a repayable grant. Repayment obligation initiates following completion of the funded project, at 3% of company revenue (excluding grants and awards) capped at 40% of the award per year not to exceed 2x the award amount. University-only awards are repaid at a rate of 25% of royalty revenue not to exceed 2x the award amount. Who can apply: Applications may be submitted by principal investigators from either private bioscience companies or from research universities located in Maryland. Formal collaborative (joint) submissions that advance research discoveries toward development of a product are encouraged and will receive priority. University sponsored projects must receive prior authorization to apply and have undergone due diligence from their technology transfer office. Application: The applicant will identify the project and specific milestones to be completed with the funding, including a budget that is linked to these milestones. The applicant must: 1. Complete the Applicant and Project Summary Forms 2. Complete the Application Details Form and include a Principal Investigator CV. 3. Companies must provide a full business plan including a 5 year pro forma financial statement, and any current and submitted grant applications including title, abstract, duration dates and budget total. University applicants must provide a list of all related current and submitted grant applications, including title, abstract, duration dates and budget total. 4. Submit electronically to grants@marylandbiocenter.org 5. Be prepared to present the project to a review panel at the Maryland Biotechnology Center Maryland Biotechnology Center Page 1 / 7 Translational Research Application TRANSLATIONAL RESEARCH APPLICATION DETAIL Project Title Project Contact Area of Translational Research (check any that apply) __ Therapeutics __ Diagnostics __ Medical Devices __ Nanobiotechnology __ AgBio __ Research Tools __Industrial Bio __Other: DESCRIPTION OF PROJECT GOALS State (1) the project goal(s) and describe how the project goal(s) fits into the product development plan or service, and (2) benefits the organization by addressing an unmet need(s). 1000 word limit (Arial 10 or Calibri 11 font) CONFIDENTIAL Maryland Biotechnology Center Page 2 / 7 Translational Research Application PROJECT MILESTONES Identify the project milestone(s) and relate each to the project goal(s). 1000 word limit (Arial 10 or Calibri 11 font) CONFIDENTIAL STAGE OF DEVELOPMENT Identify the current stage of development of this project in terms of (1) prior work, staffing and investment to date, and (2) after the successful completion of these milestones, what the expected next steps in the development path (e.g. patent, clinical trial, regulatory activity) are to commercialization. 1000 word limit (Arial 10 or Calibri 11 font) CONFIDENTIAL Maryland Biotechnology Center Page 3 / 7 Translational Research Application EXPECTED OUTCOMES AND FUTURE COMMERCIALIZATION OBJECTIVES Describe the expected outcomes of each milestone and for the project as a whole. Indicate future commercialization plan for this project including timeline and estimated required funding. 1000 word limit (Arial 10 or Calibri 11 font) CONFIDENTIAL Maryland Biotechnology Center Page 4 / 7 Translational Research Application INTELLECTUAL PROPERTY/PATENT LANDSCAPE Describe the Intellectual Property (IP) or proprietary knowledge protection prospects of the intended commercialization endpoint. Note any complementary or blocking patents or technology that would need to be licensed to successfully commercialize this product (freedom to operate). 1000 word limit (Arial 10 or Calibri 11 font) CONFIDENTIAL Maryland Biotechnology Center Page 5 / 7 Translational Research Application DETAILED BUDGET Provide a detailed project budget. Indicate total project expenses, leveraged or additional funding in place or anticipated (by when), their sources, and dedicated project staff and their annual labor costs. For Universities: Overhead costs are not funded by this award. Expenses must be tied to project milestones stated above. 1000 word limit (Arial 10 or Calibri 11 font This information may be submitted on an Excel spreadsheet CONFIDENTIAL Maryland Biotechnology Center Page 6 / 7 Translational Research Application UNIVERSITY APPLICANTS ONLY – COMPLETE THE ADDITIONAL SECTION BELOW MARKET ANALYSIS Provide (1) an analysis of the target market and market size, and (2) an analysis of competitor companies or organizations with similar products or services in development or on the market. 1000 word limit (Arial 10 or Calibri 11 font CONFIDENTIAL Maryland Biotechnology Center Page 7 / 7 Translational Research Application