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CURRICULUM VITAE
DATE: 4/17/2020
NAME:
James M. Stark, M.D., Ph.D.
PRESENT TITLE:
Visiting Professor of Pediatrics
Division Chief, Pediatric Pulmonary Medicine, Allergy/Immunology
& Rheumatology
Program Director, Pediatric Pulmonary Medicine Fellowship
Training Program
ADDRESS:
6431 Fannin MSB 3.228
Houston, Texas 77030-1503
BIRTHDATE:
10/09/1953
CITIZENSHIP: USA
UNDERGRADUATE EDUCATION:
1972-1976 The Cleveland State University
Cleveland, Ohio
B.S., Biology
(Summa Cum Laude)
GRADUATE EDUCATION:
1976-1982 Case Western Reserve University
Ph.D. in Microbiology and Molecular Biology
School of Medicine, Cleveland, Ohio Thesis Advisor, Charles W. Shuster, Ph.D.
1976-1983 Case Western Reserve University
M.D.
School of Medicine, Cleveland, Ohio
POSTGRADUATE TRAINING:
Post-Doctoral
1983-1986 Department of Pediatrics
Rainbow Babies and Children's
Hospital
University Hospitals of Cleveland
Cleveland, Ohio
1986-1989 Department of Pediatrics
Case Western School of Medicine
University Hospitals of Cleveland
Cleveland, Ohio
MILITARY SERVICE (IF APPLICABLE):
Residency in Pediatrics
(William T. Speck, Chairman, Department of
Pediatrics)
Fellowship in Pediatric Pulmonology
(Pamela B. Davis, M.D., Ph.D., Program
Director)
none
ACADEMIC APPOINTMENTS:
Assistant Professor
07/01/89-02/28/93
Department of Pediatrics
Division of Pediatric Pulmonology
University of Wisconsin Children's Hospital
Research Assistant Professor
03/01/93-09/30/98
Department of Pediatrics, Division of Pulmonary Medicine
Children's Hospital Medical Center/University of Cincinnati, Cincinnati,
Ohio
Research Associate Professor
09/01/98-09/30/99
Department of Pediatrics, Division of Pulmonary Medicine
Children's Hospital Medical Center/University of Cincinnati, Cincinnati, Ohio
Associate Director, Division of Pulmonary Medicine, CHMC, Cincinnati,
03/01/93-09/30/99
OH
Pediatric Pulmonary Fellowship Training Director, CHMC, Cincinnati,
01/01/96-12/31/98
OH
Assistant Professor, Department of Molecular Microbiology and
10/01/99-03/31/03
Immunology
University of Missouri-Columbia, Columbia, MO
Associate Professor, Department of Pediatrics, University of Texas
04/01/03-06/15/06
Health Sciences Center at Houston
Associate Professor, Department of Pediatrics, Wright State
06/17/06-06/30/11
University, Dayton Ohio
Professor, Department of Pediatrics, Wright State
07/1/11-08/31/11
University, Dayton Ohio
Visiting Professor, Department of Pediatrics, University of Texas Health
09/1/11-present
Sciences Center at Houston
HOSPITAL APPOINTMENTS:
07/01/89-02/28/93
Attending Staff
University of Wisconsin Children's Hospital
University of Wisconsin, Madison Wisconsin
03/01/93-09/30/99
Attending Staff
Children's Hospital Medical Center
10/99-3/31/03
Attending Staff
University Hospital and Clinics- University of Missouri-Columbia
08/01/04-06/15/06
Attending Physician, Memorial Herman Children’s Hospital
08/01/03-06/15/06
Active Medical Staff, Harris County Hospital District/LBJ Hospital
08/15/04-06/15/06
Medical Staff, HealthBridge Children’s Hospital
06/17/06-08/31/11
Attending Physician, Dayton Children’s Medical Center
09/28/11-present
Harris County Hospital District/LBJ General Hospital
09/01/11-present
Temporary Privileges, Memorial Hermann Hospital
LICENSURE:
Medicine
State of Texas
State of Ohio
CERTIFICATION:
1987
Diplomate, American Board of Pediatrics
1992
Diplomate, American Board of Pediatrics
Sub-Board of Pediatric Pulmonology
Certificate Number 35922
Certificate Number 362
Recertified 2006-2013
PROFESSIONAL ORGANIZATIONS (AND COMMITTEES OF THESE):
LOCAL:
REGIONAL:
NATIONAL: American Society for Microbiology, 1986-present
American Thoracic Society, 1989-present
American Thoracic Society, Program Committee,
Allergy, Immunology and Inflammation Assembly, ALA/ATS National
Meeting, 1993-1996
Pediatric Assembly, ALA/ATS International Meeting, 1997-2001
Elected to Society for Pediatric Research, 12/96
Pediatric Pulmonary Training Directors Association (PEPTDA) 19961998
HONORS AND AWARDS:
1991-1994
Harry S. Shwachman Cystic Fibrosis Clinical Investigator Award
Cystic Fibrosis Foundation
1991-1996
Clinical Investigator Award (K08)
National Institutes of Health
1986-1989
Parker B. Francis Post-doctoral Research Fellowship
Parker B. Francis Foundation
1976-1978
National Research Service Award
1981-1982
Department of Health, Education, and Welfare,
National Institutes of Health
Predoctoral Fellowship, Medical Scientists Training Program
Case Western Reserve University, Cleveland, Ohio
1979-1981
National Research Service Award
National Heart, Lung, and Blood Institute, National Institutes of Health
Predoctoral Fellowship
Case Western Reserve University
Cleveland, Ohio
EDITORIAL POSITIONS:
SERVICE ON NATIONAL GRANT REVIEW PANELS, STUDY SECTIONS, COMMITTEES:
British Columbia Lung Association, May 1996
National Institutes of Health, National Institute of Allergy and Infectious DiseasesRFA AI95-11 Mucosal and Synovial Gene Transfer, April 11, 1996
VA Medical Center, Merit Award, March 1997
National Institutes of Health, National Heart Lung and Blood Institute, SCOR in
Neurobiology of sleep and sleep apnea, airway biology and pathogenesis of Cystic Fibrosis,
and Acute Lung Injury, SCOR in Airway biology and pathogenesis of Cystic Fibrosis. RFA
HL-96-14. 1/11/98-1/12/98
British Columbia Lung Association, May 1998
The Wellcome Trust, June 1999
Michael Smith Foundation for Health Research, July 2001
National Institutes of Health, National Heart Lung and Blood Institute, SCOR in
Neurobiology of sleep and Sleep Apnea and Airway Biology and Pathogenesis of Cystic
Fibrosis. RFA HL-02-13. 3/12/03-3/13/03
National Institues of Health, Special Emphasis Panel/Initial Review Group 2005/01 LCMI (1)
10/13/2004-10/14/2004
National Institutes of Health. Heart, Lung, and Blood Special Review Committee. PPG
Review: 1 P01 HL083069-01. 13 May 2005
SERVICE ON THE UNIVERSITY OF TEXAS-HOUSTON HEALTH SCIENCE CENTER
COMMITTEES:
SERVICE ON THE UNIVERSITY OF TEXAS-HOUSTON MEDICAL SCHOOL COMMITTEES:
Graduate Education Committee member 9/1/2004- 2006
Fellowship Training Director Pediatric Pulmonology 2011- present
SERVICE ON GRADUATE SCHOOL COMMITTEES:
SERVICE ON UT-HMS AFFILIATED HOSPITAL COMMITTEES:
SERVICE TO THE COMMUNITY:
Committee Member, BSA Troop 464, Pearland, TX
Coach, Science Olympiad Northmont High School, Dayton Ohio
2004-2006
2007-2009
SPONSORSHIP OF CANDIDATES FOR POSTGRADUATE DEGREE :
(include names and years)
Advisory Committee and Examination Committee, Rebecca R. Corrigan, 2004
SPONSORSHIP OF POSTDOCTORAL FELLOWS:
(include names and years)
CURRENT TEACHING RESPONSIBILITIES:
Medical School:
MSIII Lectures- Pediatrics Rotation
Ad hoc teaching of students on rotation
Supervision of Residents during Pediatric Pulmonology rotations (1-3/month)
Ad hoc teaching of residents (Pediatrics, Transitional, Med-Peds) on misc.
Pediatrics rotations
Supervision of Pediatric Pulmonology fellows during clinical rotations and Teaching
in core research and clinical curriculum.
CURRENT GRANT SUPPORT:
amount)
(include project title, P.I., funding agency, award period and
None
PAST GRANT SUPPORT: (include project title, P.I., funding agency, award period and amount)
Cystic Fibrosis Foundation
1990-1992
New Investigator Award
Cell Biology of Parainfluenza virus Type 2
Direct Costs (annual): $32,000
Total Costs (project): $64,800
1991-1994
Cystic Fibrosis Foundation
Harry S. Shwachman Clinical Investigator Award
Respiratory Virus Infection and Airway Inflammation
Direct Costs (annual): $15,700
Total Costs (project): $52,155
1991-1996
National Institutes of Health
Clinical Investigator Award
Respiratory Virus Infection and Airway Inflammation
Direct Costs (annual): $80,730
Total Costs (project): $340,416
1991-1992
Fisons Pharmaceuticals
Effects of Nedocromil Sodium on Neutrophil Adhesion to Airway Epithelial Cells
Direct Costs (annual): $5,760
Total Costs (project): $5,760
1994-1996
Cystic Fibrosis Foundation
Adenovirus Infection and Airway Inflammation
Direct Costs (annual): $30,000
Total Costs (project): $64,800
1993-1994
Cystic Fibrosis Foundation
Adenovirus Infection and Airway Inflammation
Part of CFF RDP
PI: Jeffrey A. Whitsett, M.D.
Direct Costs (annual): $40,000
Total Costs (project): $40,000
1996-1998
Board of Trustees, Children's Hospital Medical Center
Role of ICAM-1 in RSV-Induced Pulmonary Inflammation
PI: James M. Stark, M.D., Ph.D.
Direct Costs (annual): $40,000
Total Costs (project): $40,000
1997-1999
Cystic Fibrosis Foundation
IL-1 and Adenovirus vector-induced Airway Inflammation
Direct Costs (annual): $30,000
Total Costs (project): $64,800
1997-1999
American Lung Association
Mechanisms of RSV-Induced Airway Inflammation
Direct Costs (annual) $25,000
Total Costs (project)
1998-1999
NIH: Center for Environmental Genetics
PI: G. Grabowski
Subcontract (Pilot project):
PI: J. M. Stark
Genetic Analysis of RSV Infection in a Mouse Model
Direct Costs (annual) $20,000
Total Costs (project)
$50,000
$20,000
2001-2002
Children's Miracle Network
Research Grant (PI: JM Stark)
RSV increases susceptibility to bacterial pneumonia
Direct Costs (annual) $10,000
Total Costs (project) $10,000
2001-2004
Cystic Fibrosis Foundation
Research Grant (PI: JM Stark)
RSV Enhances Susceptibility to P. aeruginosa Pneumonia
Direct Costs (annual)
$ 60,000
Total Costs (project) $129,600
04/01/01-03/31/04
2001-2005
National Institutes of Health (NIAID)
1R01 AI46556-01A1 (PI: JM Stark)
Genetic Determinants of RSV susceptibility in mice
Direct Costs (year 1) $225,000
Total Costs (project)
9/1/01-6/30/05
2004-2006
$1,208,017
National Institutes of Health, NIEHS
R21 ES012927-01 (PI: Colasurdo GN)
SP-A Signaling and Age-Dependent Vulnerability to PM
$275,000
The major goals of this project are to define the cellular regulation of SP-A and its
role in enhanced susceptibility to PM in developing mice.
Role: co-investigator
4/1/2004-3/31/2006
PENDING GRANT APPLICATIONS (include project title, P.I., funding agency, award period and
amount)
PUBLICATIONS:
A. Abstracts
1. Stark JM, O'Neil J, Nisimune T, Shuster CW. Analysis of multiple antibiotic
resistant strain of Enterobacter agglomerans. Abstracts of the Annual Meeting of
the American Society for Microbiology, 1978.
2. Shuster CW, Stark JM, O'Neil J. Properties of an ampicillin resistance plasmid
from Enterobacter agglomerans. Abstracts of the Annual Meeting of the American
Society for Microbiology, 1978.
3. Stark JM, Shuster CW. Mapping of the genes for alpha hemolysin production by
Tn5 mutagenesis in Escherichia coli. Abstracts of the Annual Meeting of the
American Society for Microbiology, 1981.
4. Stark JM, Shuster CW. Structure of the hemolysin portion of pHly185. Abstracts
of the Annual Meeting of the American Society for Microbiology, 1982.
5. Stark JM, Brooks LJ. Differences between slow and fast vital capacities in patients
with cystic fibrosis. Abstracts of the North American CF Conference, 1988.
6. Stark JM, Huang YT, Davis PB. Parainfluenza and respiratory syncytial virus
infection of cultured human airway epithelial cells- A possible model for lower
respiratory tract disease. Am Rev Respir Dis 139:A318. 1989.
7. Stark JM, Huang YT, Davis PB. Parainfluenza and respiratory syncytial virus
infection of an immortalized human tracheal epithelial cell line, 9HTEo-. Pediatric
Pulmonol Suppl 4, 134, 1989.
8. Stark JM, Kercsmar C, Tosi M. Enhanced neutrophil adherence to cultured
tracheal epithelial cells infected with human parainfluenza virus type 2. Am Rev
Respir Dis 139:A691, 1990.
9. Tosi MF, Stark JM, Hamedani A, Smith CW, Gruenert DC, and Huang YT.
Increased adhesion to human tracheal epithelial cells infected with parainfluenza
virus type 2: Role of epithelial ICAM-1 and neutrophil CD11/CD18 Adhesins.
Society for Pediatric Research, 1991 Annual Meeting.
10. Stark JM, Tosi MF. Use of a microtiter assay to demonstrate enhanced neutrophil
adhesion to human airway epithelial cells. Am Rev Respir Dis 143:A43, 1991.
11. Stark JM, Carabell SK.
Detection of enhanced neutrophil adhesion to
parainfluenza-infected airway epithelial cells using a modified myeloperoxidase
assay in microtiter format. Pediatric Pulmonol suppl 6: 301. 1991.
12. Tosi MF, Stark JM, Hamedani A, Smith CW, Gruenert DC, Huang YT. Neutrophil
adhesion to human airway epithelium: Role of epithelial ICAM-1 in cells infected
with respiratory viruses or treated with IL-1 or TNF. Pediatric Pulmonol suppl 6:
301, 1991.
13. Doran O, Shinners P, Chen, M, Stark J, Graziano FM.
Isolation and
characterization of guinea pig (Gp) epithelial cells (Ec). J. Allergy Clin Immunol
89:145. 1992.
14. Stark JM, Tosi MF. A soluble factor in supernates from parainfluenza-infected
cells increased ICAM-1 expression by airway epithelial cells but does not
significantly enhance neutrophil adhesion. Pediatric Pulmonol suppl 8:315, 1992.
15. Stark JM, van Egmond AWA, Keller SA. The de-adhesion of neutrophils from
parainfluenza virus-infected A549 airway epithelial cells results from a change in
neutrophil function over time. Pediatric Pulmonol suppl 8:281, 1992.
16. Stark JM, van Egmond AWA, Keller SA. Neutrophil adherence to A549 airway
epithelial cells is energy-dependent, reversible, and transient. Pediatric Pulmonol
suppl 8:281, 1992.
17. Graziano FM, Cook E, Stark JM. Evaluation of viral infection of guinea pig (GP)
tracheal epithelial cells. J Allergy Clin Immunol. 91:160, 1993.
18. Cook E, Stahl J, Stark JM, Graziano FM. Adhesion of guinea pig inflammatory
cells to guinea pig tracheal epithelial cells (GPTE) and a human epithelial cell line.
J Allergy Clin Immunol 91:161, 1993.
19. Stark JM, Godding V, Keller S, Sedgwick J. Tumor Necrosis Factor (TNF)
enhances eosinophil adhesion to cultured airway epithelial cells. J Allergy Clin
Immunol 91:254, 1993.
20. Stark JM, Godding V, Sorkness RL, Nagata M, Sedgwick JB. The method of cell
isolation alters eosinophil adhesion to airway epithelial cells and eosinophil
superoxide generation. Am Rev Respir Dis 147:A817, 1993.
21. van Egmond A, Keller SA, Stark JM. Neutrophil adhesion to parainfluenza virusinfected airway epithelial cells is reversible and energy-dependent, and deadhesion results from "changes" in the neutrophil. Am Rev Respir Dis 147:A474,
1993.
22. Stark JM, Amin R, Warner B, Trapnell B. Exposure of cultured airway epithelial
cells to a replication-deficient adenovirus vector increases expression of IL-8 and
ICAM-1, and enhances neutrophil adhesion to the AEC monolayers. Pediatric
Pulmonol 17:64, 1994.
23. van Egmond AWA, Stark JM. Neutrophil adhesion to parainfluenza type-2 virus
infected airway epithelial cells results in priming of superoxide generation.
Pediatric Pulmonol, suppl 9:289, 1993.
24. Godding V, Sedgwick JB, Stark JM. Respiratory virus infection enhances
eosinophil (EOS) Adhesion to airway epithelial cells (AEC): Role of EOS CD18
and AEC ICAM-1. Pediatric Pulmonol, suppl 9:289-290, 1993.
25. Amin RS, Wilmott R, Trapnell B, Stark JM. The effect of exposure of airway
epithelial cells to a replication-deficient adenovirus vector on the expression of IL-8
and ICAM-1 and the down regulation of IL-8 by dexamethasone. Am J Respir Crit
Care Med 149:A33, 1994.
26. Zhou S, Stark JM, Leikauf, GD.
Human airway epithelial cell-neutrophil
interactions increase leukotriene B4 formation. Am J Respir Crit Care Med
149:A831, 1994.
27. Stark JM, Godding, V, Sedgwick, J.B. Eosinophil (EOS) adhesion to airway
epithelial cells (AEC): The roles of EOS b2 integrins and AEC ICAM-1. Am J
Respir Crit Care Med 149:A835, 1994.
28. Stark JM, Amin R, Trapnell B. Dexamethasone treatment significantly suppresses
ICAM-1 expression induced in airway epithelial cells following exposure to a
replication-deficient adenovirus vector: Cell line differences. Pediatric Pulmonol,
suppl 10:284, 1994.
29. Schwarz YA, Amin RS, Stark JM, Trapnell B, and Wilmott RW. Exposure of
airway epithelial cell cultures to a replication-deficient recombinant adenovirus
vector results in IL-8 production secondary to IL-1 expression: Evidence for
autocrine or paracrine cytokine regulation. Pediatric Pulmonol, suppl 10:233, 1994.
30. Fiedler MA, Dollries KW, Stark JM, Wilmott RW. Direct effects of interleukin-8 (IL8) on mouse lung epithelial cell proliferation and function. Pediatric Pulmonol,
suppl 10:287-288, 1994.
31. Amin RS, Wilmott RW, Baughman R, Trapnell B, Stark JM. Replication deficient
adenovirus induces IL-8 production by alveolar macrophages in vitro. Pediatric
Pulmonol, suppl 10:224, 1994.
32. Fiedler MA, Wernke-Dollries,K, Stark JM. Early release of interleukin-8 (IL-8) by
respiratory syncytial virus (RSV) infected airway epithelial cells (AEC). Am J
Respir Crit Care Med 151:A13, 1995.
33. Evans DA, Hopkins T, Stark JM. A soluble factor produced by RSV-infected cells
induces ICAM-1 expression and enhances PMN adhesion. Am J Respir Crit Care
Med 151:A603, 1995.
34. Fiedler M, Wernke-Dollries K,Stark JM. Respiratory syncytial virus (RSV)
increases interleukin-8 (IL-8) gene transcription via NF-kappa-B activation in A549
cells. Pediatric Pulmonol, suppl 12: 275,1995.
35. van Egmond AWA., Hopkins TM, Stark JM. Neutrophils utilize different ligands for
adhesion to respiratory epithelial cells infected with Respiratory Syncytial Virus or
Parainfluenza virus: Role of viral hemagglutinins. Pediatric Pulmonol, suppl 12:
276, 1995.
36. Evans DA, Fiedler MA, Milligan L, Stark JM. RSV-Infected respiratory epithelial
cells produce IL1-a that results in ICAM-1. Pediatric Pulmonol, suppl 12:275,
1995.
37. Amin RS, Stark JM, Kitzmiller J, Wilmott R.
Transcriptional and posttranscriptional regulation of IL-8 mRNA by IL-1 and TNF in lung epithelial cells.
Pediatric Pulmonol, suppl 12: 271, 1995.
38. Amin RS, Wilmott R, Trapnell B, Kitzmiller J, Stark JM. Mechanism of increase
gene expression of IL-8 and ICAM-1 by lung epithelial cells transfected with
replication-deficient adenovirus and the effect of dexamethasone. Pediatric
Pulmonol, suppl 12:228, 1995.
39. Fiedler MA, Wernke-Dollries K, Stark JM. Effects of N-acetyl cysteine on RSVinduced IL-8 gene expression and NF-kB activation in A549 cells. Am J Respir Crit
Care Med 153: A18, 1996
40. LeVine AM, Evans D, Stanley S, Stark JM. RANTES, IL-8 and IL-11 in children
with respiratory syncytial virus (RSV). Am J Respir Crit Care Med 153: A597,
1996.
41. Rey-Rosa A, Evans D, Roberts N, Tomasi A, Reising S, Stark JM, Bernstein D,
Christie C. Complicated pneumococcal pneumonias, pleural empyemas and lung
abscesses linked to influenza A infections in healthy children. Interscience
conference on Antimicrobial Agents and Chemotherapy , New Orleans La .
Abstract K8. 1996.
42. Chini B, Milligan L, Fiedler MA, Hopkins T, Stark JM. ICAM-1 upregulation in
RSV-infected cells. Pediatric Pulmonol, suppl 13: 329, 1996.
43. Fiedler MA, Wernke-Dollries K, Stark JM. Inhibition of viral replication reverses
RSV-induced NF-kB activation and IL-8 gene expression. Pediatric Pulmonol,
suppl 13: 330, 1996.
44. Fiedler MA, Chini B, Milligan L, Wernke-Dollries K. Mort-Hopkins T, Stark JM.
Mechanisms of RSV-induced airway inflammation. Symposium, RSV after 40
years, an Anniversary Symposium. Kiawah Island, Nov 9-12, 1996. Invited
participant
45. Stark JM, Milligan L, Fiedler MA, Mort-Hopkins T. RSV infection causes
transcriptional upregulation of RANTES expression in A549 cells. Am J Respir Crit
Care Med 155: A465, 1997.
46. Chini B, Miligan L, Fiedler MA, Hopkins T, Stark JM. RSV-induced activation and
ICAM-1 gene expression. Am J Respir Crit Care Med 155, A468, 1997.
47. Kitzmiller JA, Stark JM, Wilmott RW. Reduced neutrophil response to the effects of
intratracheal murine IL-1a in a transgenic mouse with airway epithelial cell
expression of the human interleukin-1 receptor antagonist (HIL-1Ra). Am J Respir
Crit Care Med 155: A470, 1997.
48. Fiedler MA, Wernke-Dollries K, Chini BA, Stark JM. IkB degradation in the airway
epithelial cell-mediated inflammation. Pediatr Pulmonol, suppl. 14:315, 1997.
49. Ayad O, Stark JM, Wong HR. The Heat Shock Response inhibits Rantes Gene
Expression. Society of Critical Care Medicine Educational and Scientific
symposium. 1997.
50. Wernke-Dollries K, Stark JM, Fiedler M. Alteration of IkB levels in RSV-infected
A549 cells affects NF-kB activation. Am J Respir Crit Care Med 157: A739, 1998.
51. McDowell SA, Fiedler MA, Milligan L, Hopkins TM, Stark JM. Transcriptional
regulation of RANTES expression in respiratory epithelial cells (REC) following
Respiratory Syncytial Virus (RSV) infection. Am J Respir Crit Care Med 157: A605,
1998.
52. Levine AM, Koeningsknecht V, Stark JM. Decreased pulmonary clearance of
Streptococcus pneumoniae following non-lethal Influenza A infection in mice. Am J
Respir Crit Care Med 159:A107, 1999.
53. Levine AM, Gwozdz J, Stark JM, Bruno M, Whitsett J, Korfhagen T. Surfactant
protein A enhances clearance of respiratory syncytial virus in vivo. Am J Respir Crit
Care Med 159:A18, 1999.
54. D. O'Donnell D, Milligan L, Stark JM. Induction of CD95 (Fas) and Apoptosis in
Respiratory Epithelial Cell Cultures Following Respiratory Syncytial Virus Infection.
Am J Respir Crit Care Med 159: A105, 1999.
55. Pallone MN, Stark JM, Harris,C. Role of bronchoscopy in pediatric stem cell
transplant. Am J Respir Crit Care Med 159:A431, 1999.
56. Fiedler MA, Holbrook A, Stark JM. The Effects of Antibodies Targeted at The RSV
Fusion Protein on Cytokine Production. Am J Respir Crit Care Med 161:A702,
2000.
57. Cohn G, Shanley T, Fiedler M, Stark JM. The effect of heat shock on human
intercellular adhesion molecule-1 (ICAM-1) expression by A549 cells. Am J Respir
Crit Care Med 161:A155, 2000.
58. Stark JM, McDowell SA, Koeningsknecht V, Prows DR, Leikauf JE, LeVine AM,
Leikauf,GD. Genetic susceptibility to Respiratory Syncytial Virus in inbred mice.
Am J Respir Crit Care Med 163:A52, 2001.
59. Shan-Ze Wang, Cynthia L. Rosenberger, James M. Stark, Barney S. Graham, and
Kevin S. Harrod. Clara Cell Secretory Protein Modulates Lung Inflammation and
Airway Reactivity in Respiratory Syncytial Virus Infection. Am J Respir Crit Care
Med 165: A459, 2002.
60. Stark JM, LeVine AM. Respiratory syncytial virus (RSV) infection decreases
bacterial clearance and increases lung inflammation in the mouse: effect of virus
dose and mouse genetic background. NACF meeting 2002, New Orleans, LA.
61. Stark JM, Turner-Dickson AM. Sequential pulmonary infection (Respiraory
Syncytial virus-Pseudomonas aeruginosa) decreases bacterial clearance- role of
the pulmonary macrophage. Am J Respir Crit Care Med 167:A723, 2003.
62. Graff GR, Schnitzer PB, Stark JM, Smith AL. Outcome of Multi-Resistant
Pseudomonas aeruginosa (MRPA) infection in Cystic Fibrosis. Am J Respir Crit
Care Med 167: A914, 2003.
63. Berkenbosch JW, Graff GR, Stark JM. Safety and efficacy of ketamine for infant
flexible fiberoptic bronchoscopy. Pediatr Res 2003:53 part 2: 574A.
64. Spivey, JF, Berkenbosch JW, Graff GR, Stark JM. Safety and efficacy of ketamine
sedation for infant flexible fiberoptic bronchoscopy. Pediatr Crit Care Med 2003;4
(Suppl): A159 (ThP16). Presented at the 4th World Congress on Pediatric Intensive
Care, Boston, USA, June 2003.
65. Graff GR. Kreiswirth BN, Martinez J, Saiman L, Stark J, Smith A. Molecular typing
of MRSA in CF subjects from a single CF Center. Pediatri Pulmonol. 2003; 36
(S25:)308
66. Stark JM and Colasurdo GN. Early alterations in innate cellular lung defenses
following RSV lung infection: effects on the alveolar macrophage. RSV 2003,
Atlanta GA Nov 8-11.
67. Stark JM, Alcorn JL, Chiappetta CL, Jenkins G, Piedra P, and Colasurdo GN.
Surfactant protein A (SP-A) production by primary cultures of human type II
pneumocytes following RSV infection. RSV 2003, Atlanta GA Nov 8-11.
68. Colasurdo GN, Khan AM, Chiappetta CL, Xue H, Stark JM. RSV produces
persistent airway dysfunction after infection in early life in an murine model. RSV
2003, Atlanta GA Nov 8-11.
69. Wang SZ, Bao YX, Rosenberger CL, Stark JM, Harrod KS. IL-12 modulates lung
inflammatory and immune responses to RSV infection. RSV 2003, Atlanta GA Nov
8-11.
70. Berkenbosch JW, Ner Z, Stark JM, Graff GR. Remifentanil-Propofol Sedation for
Flexible Fiberoptic Bronchoscopy in Older Children. 2004. Society of Critical Care
Medicine Annual Meeting.
71. Khan AM, Stark JM Chiappetta CL Colasurdo GN. Post-Natal Exposures to RSV
and Airborne Particulate Matter Protect Against the Development of Allergic
Responses Pediatr Res, 55:335A, 2004.
72. Colasurdo GN, Khan AM, Chiappetta CL and Stark JM. RSV produces persistent
airway dysfunction in BALB/c mice following infection in early life. Am J Respir Crit
Care Med 2004; 169: A501.
73. Stark JM, Chiappetta CL, Alcorn JL, Colasurdo GN. Early alterations in innate
cellular lung defenses following RSV lung infection. Am J Respir Crit Care Med
2004; 169: A715.
74. Stark JM, Khan AM, Stark MA, Chiappetta CL, Greene TN, Colasurdo GN. RSV
infection in the CFTR knockout mouse increase susceptibility to superinfection with
Pseudomonas aeruginosa. Pediatri Pulmonol. 2004; 38(S27): A257, p276
75. Fullmer JJ, Elidemir O, Khan AM, Colasurdo GN, Stark JM. Aberrant response to
RSV in a murine model of Cystic Fibrosis- is Nitric Oxide responsible for the
increased susceptibility to respiratory pathogens? Pediatri Pulmonol. 2004; 38
(S27): A269, p280
76. Lawson JK, Khan Am, Atkins CL, Stark JM, Colasurdo GN, Fullmer J. Timing of
Exposure to Endotoxin Determines the Protecting or Exacerbating Effect on
Allergic Response. Proc Am Thoracic Soc 2005; 2:A694
77. Stark JM, Larsen GL, Khan AM, Atkins CL, Xue H, Colasurdo GN. Pattern of
Airway and Immune Response to a Primary Respiratory Syncytial Virus Infection in
Inbred Mouse Pups with Different Genetic Susceptibility: Lack of Altered Th1/Th2
Balance. Proc Am Thoracic Soc 2005; 2:A602
78. Colasurdo GN, Khan AM, Atkins CL, Xue H, Stark MA, Stark JM. Age-Specific
Effects of RSV Infection on Airway Function, Viral Clearance and NO production in
Mice: Significant Differences in Very Young and Elderly Mice. Proc Am Thoracic
Soc 2005; 2:A603
79. Khan AM, Atkins CL, Xue H, Holian A, Stark JM , Colasurdo GN. The role of SP-A
in particulate matter induced changes in airway responsiveness and inflammation
in mice. Society for Pediatric Research, Washington DC, May 2005.
80. Jon CK, Stark JM, Khan AM, Alcorn JL, Atkins BS, Xue H, Schecter MG, Larsen
GL, Colasurdo GN. Genetic susceptibility to RSV Infection in Inbred Mouse Pups:
Important role of SP-A. Proc Am Thoracic Soc 2006; 3: A411.
81. Lawson JK, Colasurdo GN, Atkins CL, Khan AM, Schecter MG, Stark JM.
Exposure of Newborn Mice to LPS Protects from Allergen (Ovalbumin)-Induced
airway Hyperresponsiveness and Airway Remodeling Independent ot Th1/Th2
Pathways. Proc Am Thoracic Soc 2006; 3: A153.
82. Stark JM, Jon CK, Khan AM, Atkins BS, Stark MA, Xue H, Larsen GL, Colasurdo
GN. Effect of Genetic Background and Age on Airway Responsiveness Following
RSV Infection in Inbred Mouse Pups. Proc Am Thoracic Soc 2006; 3:412.
83. Schecter MG, Morandi M, Holian A, Khan AM, Atkins CL, Jon CK, Stark JM,
Colasurdo GN. Functional an Cellular Response to Lipopolysaccharide and
Particulate Matter (PM-1648 and PM-Hou) in Developing Mice. Proc Am Thoracic
Soc 2006; 3: A 553.
84. Shah BS, Khan AM, Atkins CL, Schecter MG, Jon CK, Colasurdo GN and Stark
JM. Age-Dependent differences in Disease Severity and Inflammatory Responses
to RSV Infection in Young and Aged Mice. Proc Am Thoracic Soc 2006; 3:781.
85. Enrique H Rios, James M. Stark, Gaye N. Jenkins, Joseph L. Alcorn. The
presence of an amino or carboxy-terminal FLAG-tag has no effect on biosynthesis,
oligomerization and secretion of surfactant protein-A (SP-A). PAS meeting 2007,
Toronto, Canada.
86. Stark JM, Prows DR, Leikauf GD. Genetic Determinants of Respiratory syncytial
virus (RSV) susceptibility in inbred mice. Am J Respir Crit Care Med 2007;
175:A760.
87. Alcorn JL, Atkins CL, Khan AM, Stark JM, Colasurdo GN. Regulation of surfactant
protein-A (SP-A) protein in human lung epithelial cells after infection by respiratory
syncytial virus (RSV). Am J Respir Crit Care Med 2007; 175:A889.
88. Reverdin AK, Khan AM, Dsa S, Atkins CL, Jon CK, Colasurdo GN, Alcorn JL,
Stark JM. Determinant of disease severity after RSV infection in young and aged
mice. Am J Respir Crit Care Med 2007; 175:A760.
89. Reverdin AK, Stark JM, Khan AM, Atkins CL, Jon CK, Larsen GL and Colasurdo
GN. Susceptibility to RSV infection and persistent airway dysfunction in inbred
mouse pups: influence of genetic background and host response. Am J Respir Crit
Care Med 2007; 175:A697.
90. Jon CK, Stark JM, Khan AM, Alcorn JL, Atkins CL, Schecter MG, Reverdin AK and
Colasurdo GN. Genetic susceptibility to RSV in inbred mouse pups: role of
leukotriene signaling. Am J Respir Crit Care Med 2007; 175:A919.
91. Stark JM, Leikauf GD, Prows DR. Candidate genes for Respiratory Syncytial Virus
susceptibility in mice, American Society for Microbiology International Meeting,
Boston, MA June 1-5 2008.
92. Stark JM, Leikauf GD, Prows DR. Role of CFTR in RSV susceptibility: an inbred
mouse model. Pediatr Pulmonol 2008; 322:Abstr 340.
B.
Refereed Original Articles in Journals
1. Stark JM. Studies on plasmid-coded hemolytic determinants of Escherichia coli.
Doctoral dissertation, Department of Microbiology and Molecular Biology, Case
Western Reserve University, Cleveland, Ohio. 1982.
2. Stark JM, Shuster CW. Analysis of hemolytic determinants of plasmid pHly185
by TN5 mutagenesis. J Bacteriol 152:963-967, 1992
3. Stark JM, Shuster CW. The structure of cloned hemolysin DNA from plasmid
pHLY185. Plasmid 10:45-54, 1983.
4. Stark JM, Fatemi H, Amini SB, Huang, YT. Occurrence of respiratory syncytial
virus subtypes isolated from hospitalized children in Cleveland, Ohio from 19851988. Pediatr Pulmonol 11:98-102, 1991.
5. Stark JM, Huang YT, Carl J, Davis PB. Infection of cultured human tracheal
epithelial cells by human parainfluenza viruses types 2 and 3. J Virol Methods
31:31-46, 1991.
6. Tosi M, Stark JM, Smith CW, Hamedani A, Gruenert DC, Infeld MD. Induction of
ICAM-1 expression on human airway epithelial cells by inflammatory cytokines:
Effects on neutrophil-epithelial cell adhesion. Am J Respir Cell Mol Biol 7:214221,1992.
7. Tosi MF, Stark JM, Hamedani A, Smith CW, Gruenert DC, Huang YT. ICAM-1
dependent and ICAM-1-independent adhesive interactions between PMN and
human airway epithelial cells infected with parainfluenza virus type 2. J Immunol
149:3345-3349, 1992.
8. Stark JM, van Egmond AWA, Zimmerman JJ, Carabell SK, Tosi MF. Detection of
enhanced neutrophil adhesion to parainfluenza-infected airway epithelial cells
using a modified myeloperoxidase assay in a microtiter format. J Virol Methods
40:225-242, 1992.
9. Stark JM, Smith CW, Gruenert DC, Tosi MF. Neutrophil adhesion to
parainfluenza virus-infected airway epithelial cells: Possible contributions of
ICAM-1 dependent and ICAM-1 independent mechanisms. Chest 101:405-406,
1992.
10. Amin RS, Wilmott RW, Trapnell B, Stark JM. Replication deficient adenovirus
induces expression of interleukin-8 by airway epithelial cells in vitro. Hum. Gene
Ther. 6:145-153, 1995.
11. Zhou S, Stark JM, Leikauff GD. Human airway epithelial cell-neutrophil
interactions increase Leukotriene B4 formation. Journal of Applied Physiology 78:
1396-1403, 1995.
12. Godding V, Stark JM, Sedgwick JB, Busse WW. Adhesion of activated
eosinophils to respiratory epithelial cells (REC) is enhanced by tumor necrosis
factor alpha and interleukin-1 beta. Am J Respir Cell Mol Biol, 13:555-562, 1995.
13. Fiedler MA, Wernke-Dollries K, Stark JM. Respiratory syncytial virus increases
IL-8 gene expression and protein release in A549 cells. Am J. Physiol 269 (Lung
Cell Mol.Biol 13): L865-L872, 1995.
14. Stark JM, Godding V, Sedgwick JB, Busse WW. Respiratory syncytial virus
infection enhances eosinophil (EOS) adhesion to airway epithelial cells (AEC):
Role of EOS CD18 and AEC ICAM-1. J Immunol. 156:4774-4782, 1996.
15. Stark JM, Amin RS, Trapnell BC. Infection of A549 Cells with a Recombinant
Adenovirus Vector Induces ICAM-1 Expression and Increased CD-18-Dependent
Adhesion of Activated Neutrophils. Human Gene Therapy 7:1669-1681, 1996.
16. Fiedler MA, Wernke-Dollries K, Stark JM. Inhibition of viral replication reverses
respiratory syncytial virus-induced NF-k-B activation and IL-8 expression in A549
cells. J Virol. 70:9089-9092, 1996.
17. Fiedler MA, Wernke-Dollries K, Stark JM. Mechanism of RSV-induced IL-8 gene
expression in A549 cells prior to viral replication. Am J. Physiol 271(Lung Cell
Mol Biol) 15: L963-L971, 1996.
18. Wilmott RW, Kitzmiller JA, Fiedler MA, Stark JM. Generation of a transgenic
mouse with lung-specific over-expression of the human interleukin-1 receptor
antagonist protein. Am J Respir Cell Mol Biol. 18:429-434, 1998.
19. Chini B., Fiedler MA, Mort-Hopkins T, Milligan L, Stark JM. Mechanisms of RSVinduced ICAM-1 expression. J. Virol. 72:1623-26, 1998.
20. Fiedler MA, Wernke-Dollries K, and Stark JM. Inhibition of TNFa-induced NF-kB
activation and IL-8 release in A549 cells using the proteasome inhibitor MG-132.
Am J Respir Cell Mol Biol. 19:259-268, 1998.
21. LeVine AM, Kurak KE, Bruno MD, Stark JM, Whitsett JA, Korfhagen TR.
Surfactant Protein-A deficient mice are susceptible to Pseudomonas aeruginosa
infection. Am J Respir Cell Mol Biol. 19:700-708, 1998.
22. Ayad O, Stark JM, Menendez IY, Ryan MA, Wong HR. The heat shock response
inhibits RANTES gene expression in cultured human lung epithelium. J Immunol.
161: 2594-2599, 1998.
23. D. O'Donnell D, Milligan L, Stark JM. Induction of CD95 (Fas) and Apoptosis in
Respiratory Epithelial Cell Cultures Following Respiratory Syncytial Virus
Infection. Virology 257:198-207, 1999.
24. LeVine AM, Gwozdz J, Stark JM, Bruno M, Whitsett J, Korfhagen T. Surfactant
protein A enhances clearance of respiratory syncytial virus in vivo. J Clin Invest.
103: 1015-1021, 1999.
25. Schwarz, Y, Amin RS, Stark JM, Trapnell BC, Wilmott RW. IL-1 receptor
antagonist (IRAP) inhibits IL-8 expression in respiratory epithelial (A549) cells
infected in vitro with a replication-deficient recombinant adenovirus vector. Am J
Respir Cell Mol Biol. 21: 388-394, 1999.
26. Zimmerman N, Daugherty BL, Stark JM, Rothenberg ME. Induction of functional
CC chemokine receptor-3 in the eosinophilic cell line AML 14.3D10. J Imunol.
164:1055-1064, 2000.
27. LeVine AM, Koenigknecht V, Stark JM. Decreased Pulmonary Clearance of S.
pneumoniae following influenza A infection in mice. J Virol Methods 94: 173-186,
2001.
28. Kohn G, Wong HR, Bsesh K, Zhao B, Vasi N, Denenberg A, Morris C, Stark JM,
Shanley TP. Heat Shock inhibits TNF-induced ICAM-1 expression in human
endothelial cells via I kappa kinase (IKK) inhibition. Shock.17:91-7, 2002.
29. Stark JM, McDowell SA, Prows DR, LeVine AM, Leikauf GD. Genetic
susceptibility to respiratory syncytial virus infection in mice. J Med Virol 67:92-100,
2002.
30. Wang SZ, Rosenberger CL, Bao YX, Stark JM, Harrod KS. Clara Cell Secretory
Protein modulates lung inflammatory and immune responses to respiratory
syncytial virus infection. J Immunol 2003; 171: 1051-1060.
31. Wang SZ, Bao YX, Rosenberger CL, Tesfaigzi Y, Stark JM, Harrod KS. IL-12p40
and IL-18 modulate inflammatory and immune responses to respiratory syncytial
virus infection. J Immunol. 2004; 173:4040-9.
32. Fullmer JJ, Khan AM, Elidemir O, Chiappetta C, Stark JM, Colasurdo GN. Role
of Cysteinyl Leukotrienes in Airway Inflammation and Responsiveness Following
RSV Infection in BALB/c Mice, Pediatr allergy Immunol 2005;16: 593-601.
33. Stark JM, Khan AM, Chiappetta C, Xue H, Patel T, Colasurdo GN. Immune and
Functional Role of Nitric Oxide in a Mouse Model of RSV Infection. J Infect Dis
2005. 191:287-395
34. Fullmer JJ, Khan AM, Elidemir O, Chiappetta C, Stark JM, Colasurdo GN. Role
of Cysteinyl Leukotrienes in Airway Inflammation and Responsiveness Following
RSV Infection in BALB/c Mice, Pediatr allergy Immunol 2005;16: 593-601.
35. Alcorn JL, Stark JM, Chiappetta CL, Jenkins G, Colasurdo GN. Effects of RSV
infection on Pulmonary Surfactant Protein in Cultured Human Type II Cells:
Contrasting Consequences on SP-A mRNA and Proteins. Am J Physiol Lung cel
Mol Physiol 2005; 289: L1113-1122.
36. Stark JM, Stark MA, Colasurdo GN, LeVine AM. Decreased Pulmonary
Clearance of Streptococcus pneumoniae Following Respiratory Syncytial Virus
Infection in Mice. J Med Virol 2006; 78: 827-838
37. Colasurdo GN, Fullmer JJ, Elidemir O, Atkins C, Khan AM, Stark JM. Respiratory
syncytial virus infection in a murine model of cystic fibrosis. J Med Virol. 2006;
78:651-8.
38. Stark JM, Barmada MM, Winterberg AV, Majumber N, Gibbins WJ Jr., Stark MA,
Sartor MA, Medvedovic M, Kolls J, Bein, K, Maalaparambil B, Krueger M,
Heinzmann A, Leikauf GD, Prows DR. Genomewide association analysis of
severe respiratory syncytial virus infection. J Virology 2010, 2009; 84: 2257-2269
Clinical
1. Weatherly MR, Stark JM, Rao PS, Askin F, Gilbert-Barness E. Pathological
case of the month. Am J Dis Child. 146:427-428, 1992.
2. Graff GR, Stark JM, Berkenbosch JW, Holcomb GW III, Garola RE. Chronic
Lung Disease After Activated Charcoal Aspiration. Pediatrics 109:959-961,
2002.
3. Berkenbosch JW, Graff GR, Stark JM. Safety and efficacy of ketamine sedation
for infant flexible fiberoptic bronchoscopy.Chest. 2004;125:1132-7
4. Berkenbosch JW, Graff GR, Stark JM, Ner Z, Tobias JD. Use of a remifentanilpropofol mixture for pediatric flexible fiberoptic bronchoscopy sedation. Paediatr
Anaesth. 2004;14:941-6.
5. Graff GR, Stark JM, Grueber R. Nebulized Fentanyl for end of life care in Cystic
Fibrosis. Respiration 2004; 71:646-649.
C.
Invited Articles (Reviews, Editorials, etc.) in Journals
1) Stark JM, Busse WW. Respiratory virus infection and airway hyperreactivity in
children. Pediatric Allergy Immunol 2:95-110, 1991.
2) Stark JM. Lung infections in children. Curr Opin Pediatr 5:273-280, 1993.
3) Acton JD, Stark JM. Management of Acute Exacerbations of Cystic Fibrosis
Lung Disease. Clinical Pulmonary Medicine 6: 153-164, 1999.
4) Wilmott RW, Khurana-Hershey G, and Stark J.M. Current Concepts on
Pulmonary Host Defense Mechanisms in Children. Curr Opin Pediatr. 12: 187193, 2000.
5) Stark JM. Models for the study of respiratory syncytial virus infection and
disease. Drug Discovery Today: Disease Models 2006; 3:63-68 (epub).
D.
Chapters
1) Cypcar D, Stark JM, Lemanske RF. Impact of respiratory infections on asthma.
Pediatr Clin North Am 39:1259-1276, 1992.
2) Stark JM. Adhesion molecules and airway inflammation. In: Adkinson N.F., ed.
Allergy: Principles & Practice, Update Number 13. St. Louis: Mosby, pp 117, 1992.
3) Busse WW, Lemanske RF Jr, Stark JM, Calhoun WJ. Role of respiratory
infections. In Holgate ST, Austen KF, Lichtenstein LM, Kay AB, eds. Asthma:
Physiology, Immunopharmacology, and Treatment. Boston, MA: Academic
Press, pp 345-355, 1993.
4) Stark JM and Graziano FM. Lower airway response to virus. In: Busse WW,
Holgate S, eds. Asthma and Rhinitis. Cambridge, MA: Blackwell Scientific
Publications, Inc., Chapter 93, pp 1229-1243, 1995.
5) Wilmott RW, Fiedler MA, Stark JM. Host Defense Mechanisms. In: Chernick V
and Boat TF, Eds. Disorders of the Respiratory Tract in Children, 6th
Edition. WB Saunders Co. Philadelphia, PA. Chapter 12, pp 238-264, 1997.
6) Schroth MK, Stark JM, Sedgwick JB, Busse WW. Eosinophil-Epithelial
interactions and transepithelial migration, In: Bochner BS ed. Adhesion
Molecules in Allergic Disease, Marcel Dekker, Inc. NY, NY. Chapter 11, 201226, 1997.
7) Fiedler MA, Stark JM. Viral Pneumonia and Antiviral Therapy, in: Wilmott RW
ed. The Pediatric Lung, Birkhauser Publishing Ltd. Basel, Switzerland. Chapter
4, pp 83-112, 1997.
8) Stark JM. The induction of chemokines by viruses in allergic states, in:
Rothenberg ME ed. Chemokines and Allergic Disease. Marcel Dekker, Inc., New
York, NY. Chapter 13, pp 263-287, 2000.
9) Stark JM. Leukocyte-Endothelial Adhesion. In: Busse WW, Holgate S, eds.
Asthma and Rhinitis. Second Edition. Cambridge, MA: Blackwell Scientific
Publications, Inc. Chapter 46, pp 702-720, 2000.
10) Stark JM and Colasurdo GN. Lung Defenses. In: Chernick V, Boat TF, Wilmott
WW, Bush A, Eds. Disorders of the Respiratory Tract in Children, 7th Edition.
WB Saunders Co. Philadelphia, PA. 2006. Chapter 12, pp205-223.
11) Stark JM. Pulmonary Manifestations of Immunosuppressive Diseases Other
Than Human Immunodeficiency Virus (HIV) Infection. In: Turcios NL and Fink RJ
Eds. Pulmonary Manifestations of Pediatric Systemic Diseases Saunders
Elsevier Inc. Philadelphia PA 2009, Chapter 3, pp49-78.
12) Stark JM, Mueller G. Lung Defenses. In: Chernick V,Boat TF, Wilmott WW,
Bush A, Eds. Disorders of the Respiratory Tract in Children, 8th Edition. WB
Saunders Co. Philadelphia, PA. 2011, pp89-109.
E.
Books
F.
Other Professional Communications
Presentations
5/12-5/15/91
Roundtable discussion leader: "Respiratory Syncytial Virus Vaccine
Development" Annual Meeting of the American Thoracic Society, Anaheim, CA
Invited Speaker, Aspen Lung Conference, entitled: "Neutrophil adhesion to
6/5-6/8/91
parainfluenza virus-infected human airway epithelial cells: Possible contributions of
ICAM-1 dependent and ICAM-1 independent mechanisms."
Invited Speaker, "Infections" , presented as part of: Update in Allergy and Clinical
10/1-10/2/92
Immunology, University of Wisconsin, Madison, WI
10/15/- 10/18/92 Sixth Annual North American Cystic Fibrosis Conference
Speaker, Workshop session: "Neutrophil Adherence to Parainfluenza virus-infected
A549 Airway Epithelial Cells is Energy-dependent, Reversible, and Transient.
Sixth Annual North American Cystic Fibrosis Conference
Speaker, Workshop session: "A soluble factor in supernates from parainfluenzainfected cells increases ICAM-1 expression by airway epithelial cells but does not
significantly enhance neutrophil adhesion."
5/16-5/19/1993 American Thoracic Society, American Lung Association 1993 International
Conference
Chairman, Mini-Symposium entitled "Airway Eosinophil Recruitment", and,
Featured Speaker, "Recruitment and Activation of Airway Eosinophils"
10/13-10/16/93 Seventh Annual North American Cystic Fibrosis Conference
Invited Discussion Leader and Speaker, Rise'N Shine Roundtable: "Pathogenic
Role of Virus Infections in CF", presented 10/14 and 10/15/94.
Speaker, Symposium Session "Late-Breaking Science", entitled, "Exposure of
cultured airway epithelial cells to a replication-deficient adenovirus vector increases
expression of IL-8 and ICAM-1, and enhances neutrophil adhesion to the AEC
monolayers"
American Thoracic Society/American Lung Association International
5/21-5/35/94
Conference.
Chairman and Facilitator , Poster Session, entitled: "Therapeutic Modulation of
Allergic Inflammation"
Invited Speaker, American Thoracic Society/American Lung Association
5/21/94
International Conference Postgraduate Course Entitled: "Development of Mouse
Models for Lung Injury and Inflammation Using Molecular biology Techniques".
American Thoracic Society/American Lung Association International
5/21/94
Conference
Course Organizer, Postgraduate Course Entitled: "Development of Mouse Models
for Lung Injury and Inflammation Using Molecular Biology Techniques". (Organized
the course content and invited speakers, developed printed teaching materials
(syllabus) for this course.
Invited Participant, "Workshop on Tuberculosis in Children", CDC, Atlanta, GA.
8/1-8/3/94
Invited Speaker, Pulmonary Research Conference, Rainbow Babies and Children's
8/4/94
Hospital, Cleveland, Ohio, talk entitled "Adenovirus Gene Vectors and Inflammation
in vitro in cultured human airway epithelial cells."
Invited Speaker, Section of Allergy and Immunology, University of Wisconsin9/16/94
Madison, entitled, "Adenovirus gene vectors and pulmonary inflammation."
10/20-10/23/94 Eighth Annual North American Cystic Fibrosis Conference
Invited Discussion Leader and Speaker, Rise'N Shine Roundtable: "Pathogenic
Role of Virus Infections in CF", Presented 10/21 and 10/22/94
Speaker, "Dexamethasone Treatment Significantly Suppresses ICAM-1 Expression
Following Exposure to a Replication-Deficient Adenovirus Vector: Cell Line
Differences Exist".
Invited speaker, Symposium on Nursing Management of Pediatric Respiratory
12/5/94
Disease, entitled "Pediatric Tuberculosis", Children's Hospital Medical Center,
Cincinnati, OH, USA
Chairman and invited speaker: Transgenic mouse models as tools for studying
5/11/96
lung inflammation, fibrosis and development. Postgraduate Course, ATS
international conference, New Orleans, LA
Invited speaker, Allergy Conference: Role of the respiratory epithelium in
10/9/97
modulating airway inflammation following viral lower respiratory tract infections.
Divisions of Pulmonary and Critical Care Medicine, and Allergy and Immunology,
Washington University School of Medicine, St. Louis, MO
Moderator and invited speaker: Respiratory syncytial virus infection in patients
10/25/97
with cystic fibrosis. Workshop, 1997 International Cystic Fibrosis Meeting, Nashville,
TN.
Invited Speaker: The RSV Virus and issues in Vaccine Development. Midwest
1/23/98
Critical Care Symposium in Neonatology. 1/22-1/23 1998. Chicago, IL.
Chairman and Speaker: Models for Pulmonary Development and Differentiation:
4/24/98
Introduction and Overview. Postgraduate Course, 1998 ALA/ATS International
Conference, Chicago, IL.
Invited Speaker: Virus-induced Airway Inflammation: Respiratory Syncytial Virus.
4/27/98
Symposium, 1998 ALA/ATS International Conference. Chicago, IL.
Invited Speaker: Responses to viral infection. Cystic Fibrosis Foundation. 1998
6/1/98
Williamsburg Conference, May 31-Jun5, 1998, Williamsburg, VA.
Roundtable moderator and speaker: Contribution of viral infection to CF lung
10/17/98
disease. 1998 International Cystic Fibrosis Foundation Meeting, Montreal, Quebec,
Canada
Chairman, Poster Discussion Session: Virus-induced airway inflammation. 1999
4/25/99
ALA/ATS International Conference, San Diego, California
Invited Speaker: Clinical Year in Review-Pediatric Pulmonary Infections. 1999
4/27/99
ALA/ATS International Conference, San Diego, California.
Symposium Chairman : Respiratory virus infections in Asthma. Speaker:
4/28/99
Epithelial responses in virus-induced airway inflammation. 1999 ALA/ATS
11/6/99
11/10/99
05/08/00
05/09/00
5/18/01
5/23/01
5/21/02
10/5/02
5/25/04
10/14/04
05/07
10/08
09/09
02/12
04/13
International Conference, San Diego, California
Invited Speaker: RSV and Chronic Lung Disease.1999. 3rd Annual Midwest Critical
Care Symposium for Neonatology, Cincinnati, Ohio
Invited Speaker: The Cellular Biology of RSV. 1999. RSV after 43 Years. Stuart,
Florida.
Symposium Chairman: Genetic Determinants of Lung Disease. Speaker:
Overview. 2000 ALA/ATS international conference, Toronto, Ontario, Canada
Symposium Chairman: RSV Infection and Airway Inflammation. Invited
speaker: ALA/ATS international conference, Toronto, Ontario, Canada Cellular
Responses of Respiratory Epithelial Cells to RSV Infection. 2000
Postgraduate Course Chairman and Invited Speaker: Genetic Analysis of Lung
development and Injury using Mouse Models: Background: ALA/ATS
International Conference, San Francisco, California, USA 2001
Invited Speaker: Antiviral agents for Lung infections in children. Symposium,
2001 ALA/ATS International Conference, San Francisco, California, USA.
Chairman and Invited Speaker, Pathogenesis of RSV bronchiolitis
Minisymposium, 2002 ALA/ATS International Conference, Atlanta, GA, USA.
Invited Speaker: Respiratory Syncytial Virus (RSV) infection decreases
bacterial clearance and increases lung inflammation in the mouse: effect of
virus dose and mouse genetic background. Workshop 22: Update on
Pathogenesis of P. aeruginosa. North American Cystic Fibrosis Conference, New
Orleans, LA, USA.
MiniSymposium, Abstract: RSV Produces Persistent Airway Dysfunction in BALB/c
Mice Following Infection in Early Life. 2004 ALA/ATS International conference,
Orlando, FL, USA.
Workshop: RSV Infection in the CFTR knockout mouse increases susceptibility to
superinfection with Pseudomonas aeruginosa. 2004 North American Cystic Fibrosis
Conference, St. Louis, MO, USA.
Genetic Determinants of Respiratory Syncytial Virus (RSV) susceptibility in inbred
mice. ATS International Meeting in San Francisco CA.
Role of CFTR in RSV susceptibility in mice: an inbred mouse model. North American
Cystic Fibrosis Conference, Orlando FL
Asthma Overview: The Problem of Asthma and Asthma Pathophysiology, American
Lung Association Asthma Educator Institute, Mason Ohio
Grand Rounds, “Bronchiolitis 2012”, UTHealth, Pediatric Department, Houston TX
Grand Rounds, “Lung Defenses”, UTHealth, Pediatric Department, Houston TX
2. Non-refereed publications
3. Letters to the Editor
4. Scientific Exhibits
5. Videos
6. Other
G. Visiting Professorships
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