STAFF LABORATORY of Immunopathology and Experimental

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STAFF
LABORATORY of Immunopathology and Experimental Immunotherapy
Head: Professor Tchavdar Vassilev, MD, DSc
e-mail: [email protected], tel: +359 2 979 6348
Assoc. Professor Andrey Tchorbanov, PhD, [email protected],
Assoc. Professor Anastas Pashov, PhD, [email protected]
Assist. Professor Iglika Djoumerska-Alexieva, MD, PhD, [email protected]
Assist. Professor Nikolina Mihaylova, PhD, [email protected]
Assist. Professor Kalina Nikolova, PhD, [email protected]
Nikola Kerekov, PhD student, [email protected]
Vera Gesheva, PhD student, [email protected]
Iva Ivanova, PhD student, [email protected]
Shina Pashova, PhD student, [email protected]
Stela Chausheva, Student, [email protected]
Ilian Manoilov, Student, [email protected]
tel: +359 2 979 6348, +359 2 979 3140, +359 2 979 6357
LABORATORY of Immunomodulators
Head: Professor Nina Ivanovska, DSc
e-mail: [email protected], tel: +359 2 979 3195
Assoc. Professor Petya Dimitrova, PhD, [email protected]е
Viktoriya Milanova, PhD student, [email protected]
Valeriya Gyurkovska, PhD student, [email protected]
tel: +359 2 979 3195, +359 2 979 3131, +359 2 979 3184
LABORATORY of Nonspecific Resistance
Head: Assoc. Professor Hristo Neychev, DVM, PhD
e-mail: [email protected]; tel: +359 2 979 3158
Assist. Professor Tsvetanka Stefanova, PhD, [email protected]
Researcher Petya Stoyanova, DVM, [email protected]
tel: +359 2 979 3158
ANIMAL Facility and work with lab animals
Head: Researcher Petya Stoyanova, DVM, [email protected]
tel: +359 2 979 3158
PROJECTS
1. NSF* DDVU 10-250 (2011-2014): Functional elimination of autoreactive T cells by antibody
therapy in murine and humanized SCID models of Systemic lupus erythematosus and
Multiple sclerosis. PI: Assoc. Prof. Andrey Tchorbanov.
2. ACIP A_05/11 (2011-2013): The role of neutrophils and NK cells in the development of
collagenase-induced osteoarthritis. PI: Assoc. Prof. Petya Dimitrova, Institute of
Microbiology-Sofia, Co-PI: Prof. Angela Santoni, University La Sapienza-Rome, Co-PI: Crina
Stavaru, Cantacuzino Institute-Bucharest, Romania.
3. NSF RILA 013 (2011-2012): Induction of tolerance to factor VIII in hemophilia A. PI: Assoc.
Prof. Anastas Pashov; Co-PI: Dr. Sebastien Lacroix-Desmazes, U872(Eq16) INSERM, Paris,
France.
4. NATO/PIRG05-GA-2009-248289 (2010-2013): Translational study on the antigen presenting
properties of human vs mouse B cell subpopulations. PI: Assoc. Prof. Anastas Pashov.
5. NSF DTK 02/19 (2010-2013): DNA vaccines: Viral Antigen Targeting by Genetically Engineered
Chimeric Molecules. PI: Assoc.Prof. Andrey Tchorbanov.
6. ЕBR Collaboration Bulgaria-Hungary (2010-2012): DNA Viral Antigen Targeting by Genetically
Engineered Chimeric Molecules. PI: Assoc.Prof. Andrey Tchorbanov. Co-PI: Jozsef Prechl,
University Eötvös Lorand, Budapest, Hungary.
7. NSF/DTK 02/78 (2010-2013): Antitumor activity of Gastropodan hemocyanins. PI: Assoc.Prof.
Andrey Tchorbanov.
8. NSF/DRNF 02/11: Biologic response of neoplastic and auto-immune B-cells to chimeric
protein-engineered antibodies: flow cytometry analysis of apoptosis using novel cyanine
nucleic acid dyes. PI: Assoc. Prof. Petya Dimitrova, Co-PI: Assoc. Prof. Georgi Balazenko,
National Hematology Clinic – Sofia, Co-PI: Prof. Todor Deligeorgiev, Chemical Faculty- Sofia
University.
9. NSF/DO 02-312/08: Suppression of allergen-specific B lymphocytes in humanized SCID mice
using Chimeric protein-engineered antibodies. PI: Assoc.Prof. Andrey Tchorbanov.
10. VU 704/07 2007-2011): New approach for selective suppression of autoreactive B cells by a
chimeric anti-CD35 antibody. PI: Assoc. Prof. Andrey Tchorbanov
11. VUH 11/07 (2007-2011): Creation of engineered chimeric molecules by protein technology
for therapy of autoimmune diseases. PI: Assoc. Prof. Andrey Tchorbanov
NSF*: National Science Fund
PUBLICATIONS
2011
Belenska L, Dimitrova P, Ivanovska N. Influence of complement depletion on the development of zymosaninduced arthritis. The Youth Scientific Conference “Kliment`S Days” Conference Proceedings-Conference
Proceedings, 2011, 1st edition, 2nd book, 15-18, ISSN: 1314-4960.
Dimitrov J, Pashov A, Vassilev T. Antibody polyspecificity – what does it matter? In: Natural Antibodies.
Lutz H. (Editor), Landes Biosciences, Austin, TX, USA, 2011, ISBN: TBA.
Dimitrova P, Ivanovska N. How important are innate immunity cells in osteoarthritis pathology. In:
Osteoarthritis. Book 1. InTech, Rijeka, Croatia, 2011. ISBN: 979-953-307-082-6.
Dimitrova P, Toncheva A, Gyurkovska V, Ivanovska N. Involvement of soluble receptor activator of nuclear
factor-κB ligand (sRANKL) in collagenase-induced murine osteoarthritis and human osteoarthritis.
Rheumatol Int 3, 2011. ISSN: 0172-8172.
Dimitrova P, Vassilev T, Shivarov V. AICDA inhibition or overactivation to eliminate pathological B cell
clones? Arthritis Rheum 63, 2011, 3174-3175. ISSN: 1529-0131.
Dineva J, Vangelov I, Todorova K, Stefanova T, Nikolov G, Gulenova D, Ivanova M. Relationship of nitrate
levels in follicular fluids (FFls) and rate of apoptotic human granulosa luteinized cells (GLCs) with the
COH/IVF outcome. Proceedings Bulgarian Acad Sci 2011, in press. ISSN: 1310-1331.
Djoumerska-Alexieva I, Vassilev V. Enhanced binding polyreactivity of human IgG after acid pH treatment.
Proceedings Bulgarian Acad Sci 64, 2011, 1187-1192. ISSN: 1310-1331.
Gesheva V, Idakieva K, Kerekov N, Nikolova K, Mihaylova N, Doumanova L, Tchorbanov A. Rapana
thomasiana hemocyanin as adjuvant of non-conjugated bacterial and viral proteins. Advances in Bulgarian
Sciences, 2010, 2011, 21-29, ISSN: 1313-2563.
Gesheva V, Idakieva K, Kerekov N, Nikolova K, Mihaylova N, Doumanova L, Tchorbanov A. Marine
gastropod hemocyanins as adjuvants of non-conjugated bacterial and viral proteins. Fish Shellfish Immunol
30, 2011, 135-142. ISSN: 1050-4648.
Gyurkovska V, Alipieva K, Maciuk A, Dimitrova P, Haas C, Bley T, Georgiev M. Anti-inflammatory activity of
Devil's claw in vitro systems and their active constituents. Food Chemistry 125, 2011, 171-178. ISSN: 03088146
Idakieva K, Gesheva V, Mihaylova N, Doumanova L, Tchorbanov A. Rapana thomasiana hemocyanin as a
protein carrier and adjuvant of bacterial and viral vaccines. In: Gastropods: Diversity, Habitat and Genetics.
Bianchi A, Fields J. (Editors). Nova Science Publishers, Inc 2011, ISBN: 978-1-61324-695-5.
Ivanovska N, Dimitrova P. Bone resorption and remodeling in murine collagenase-induced osteoarthritis
after administration of glucosamine. Arthritis Res Ther 16, 2011, R44. ISSN: 1478-6354.
Kaloyanova S, Ivanova I, Tchorbanov A, Dimitrova P, Deligeorgiev T. Synthesis of chloro-substituted analogs
of Thiazole orange - Fluorophores for flow cytometric analyses. J Photochem Photobiol B 103, 2011, 215221. ISSN: 1011-1344.
Kerekov N, Mihaylova N, Prechl J, Tchorbanov A. Humanized SCID mice models of SLE. Curr Pharm Des 17,
2011, 1261-1266. ISSN: 1381-6128.
Kerekov NS, Mihaylova NM, Grozdev I, Todorov TA, Nikolova M, Baleva M, Nikolova M, Prechl J, Erdei A,
Tchorbanov AI. Elimination of autoreactive B cells in humanized SCID mouse model of SLE. Eur J Immunol
41, 2011, 3301-3311. ISSN: 1521-4141.
Kostova I, Grigorov P, Balkansky S, Stefanova T. Synthesis, characterization and cytotoxicity of newHo(III)
and Er(III) complexes. Indian J Biotechnology 10, 2011, 387-394. ISSN: 0972-5849.
Mihaylova N, Tchorbanov A. New biotechnology approaches for immunotherapy of autoimmune diseases.
Biotech Biotechnological Equipment 25, 2011, 24-29. ISSN: 1310-2818.
Mihaylova N, Tchorbanov A. Selective Immunotherapy by engineered chimeric molecules. Acta Facultatis
Medicae Naissensis 28, 2011, 5-15. ISSN: 0351-6083.
Milanova V, Ivanovska N, Dimitrova P. Neutrophils in zymosan-induced arthritis: the source of proinflammatory cytokines. The Youth Scientific Conference “Kliment`S Days” Conference
Proceedings 2011, 1st edition, 2nd book, 61-64, ISSN: 1314-4960.
Milanova V, Toncheva A, Ivanovska N, Dimitrova P. IL-17 and neutrophils in the pathology of rheumatoid
arthritis. Rheumatology (Sofia) 1, 2011, 37-45. ISSN: 1310-0505.
Milanova V, Toncheva A, Ivanovska N, Dimitrova P. The significance of animal models of rheumatoid
arthritis. Rheumatology (Sofia) 3, 2011, 47-54. ISSN: 1310-0505.
Nikolova K, Gesheva V, Vassilev T. Novel therapeutic approach prevents splenomegaly in lupus-prone mice
with an apoptosis defect. Proceedings Bulgarian Acad Sci 64, 2011, 241-246, ISSN: 1312-2436.
Pashov A, Delignat S, Bayry J, Kaveri SV. Enhancement of the affinity of glucocorticoid receptors as a
mechanism underlying the steroid-sparing effect of intravenous immunoglobulin. J Rheumatol 38, 2011,
2275. ISSN: 0315-162X.
Pashov A, Monzavi-Karbassi B, Kieber-Emmons T. Glycan mediated immune responses to tumor cells. Hum
Vaccine, 7, 2011, 156-165. ISSN: 2164-5515.
Pavlovic S, Zdravkovic N, Dimitrov J, Djukic A, Arsenijevic N, Vassilev T, Lukic M. Intravenous
immunoglobulins exposed to heme (heme IVIG) are more efficient than IVIG in attenuating autoimmune
diabetes. Clin Immunol 138, 2011, 162-171. ISSN: 1521-6616.
Saha S, Pashov A, Monzavi-Karbassi B, Kieber-Emmons AM, Otaki A, Murali R, Kieber- Emmons T.
Carbohydrate Mimetic Peptide. In: Vaccines Anticarbohydrate Antibodies. Kosma P., Müller-Loennies S
(Editors). Springer, Vienna, 2011, 229-254, ISBN: 3709108691.
Stefanova T, Nikolova N, Neychev H, Zlabinger G. Phagocytosis and killing of Salmonella by 7hydroxycoumarin activated macrophages. Immunol Invest 2011. DOI:10.3109/08820139.2011.619021.
ISSN: 0882-0139.
Динева Ж, Вангелов И, Стефанова Цв, Гуленова Д, Николов Г, Иванова М. Изследвания върху ролята
на азотния оксид (NO) в преовулаторния човешки фоликул. Репрод. Здраве 18, 2011, ISSN: 1312-6180.
2010
Dimitrov J, Planchais C, Kang J, Pashov A, Vassilev TL, Kaveri SV, Lacroix-Desmazes S. Heterogeneous
antigen recognition behavior of induced polyspecific antibodies. Biochem Biophys Res Commun 398, 2010,
266-271
Dimitrova I, Gesheva V, Nikolova K, Mihaylova N, Todorov T, Nikolova M, Tchorbanov A. (2010). Target
silencing of disease-associated B-lymphocytes by chimeric molecules in SCID model of pristane-induced
autoimmunity. Lupus 19, 2010, 1261-71.
Dimitrova P, Ivanovska N, Schwaeble W, Gyurkovska V, Stover C. The role of properdin in murine zymosaninduced arthritiw. Mol Immunol 47, 2010, 1458-1466.
Djoumerska-Alexieva I, Dimitrov J, Voynova E, Lacroix-Desmazes S, Kaveri S, Vassilev, T. Exposure of IgG to
an acidic environment results in molecular modifications and in enhanced protective activity in sepsis.
FEBS J 277, 2010, 3039-3050.
Nikolova K, Mihaylova N, Voynova E, Kerekov N, Gesheva V, Prechl J, Nikolova M, Tchorbanov A. Reestablishing tolerance to DNA in humanized and murine models of SLE. Autoimmun Rev 9, 2010, 499-502.
Papp K, Végh P, Tchorbanov A, Vassilev T, Erdei A, Prechl J. (2010). Progression of lupus-like disease drives
the appearance of complement-activating IgG antibodies in MRL/lpr mice. Rheumatology (Oxford) 49,
2010, 2273-2280.
Pashov A, Monzavi-Karbassi B, Raghava GP, Kieber-Emmons T. Bridging innate and adaptive antitumor
immunity targeting glycans. J Biomed Biotechnol 2010, 2010, 354068.
Todorova VK, Klimberg VS, Hennings L, Kieber-Emmons T, Pashov A. Immunomodulatory effects of
radiofrequency ablation in a breast cancer model. Immunol Invest 39, 2010, 74-92.
СЪСТАВ
ЛАБОРАТОРИЯ по имунопатология и експериментална имунотерапия
Ръководител: Професор д-р Чавдар Василев, дмн
e-mail: [email protected], tel: +359 2 979 6348
Доцент д-р Андрей Чорбанов, [email protected],
Доцент д-р Анастас Пашов, [email protected]
Гл. асистент д-р Иглика Джумерска-Алексиева, [email protected]
Гл. асистент д-р Николина Михайлова, [email protected]
Асистент Калина Николова-Ганева, [email protected]
Докторант Никола Кереков, [email protected]
Докторант Вера Гешева, [email protected]
Докторант Ива Иванова, [email protected]
Докторант Шина Пашова, [email protected]
Биолог-студент Стела Чаушева, [email protected]
Биолог-студент Илиян Маноиловt, [email protected]
tel: +359 2 979 6348, +359 2 979 3140, +359 2 979 6357
ЛАБОРАТОРИЯ по имуномодулатори
Ръководител: Професор д-р Нина Ивановска, дбн
e-mail: [email protected], tel: +359 2 979 3195
Доцент д-р Петя Димитрова, [email protected]е
Докторант Виктория Миланова, [email protected]
Докторант Валерия Гюрковска, [email protected]
tel: +359 2 979 3195, +359 2 979 3131, +359 2 979 3184
ЛАБОРАТОРИЯ по неспецифична резистентност
Ръководител: Доцент д-р Христо Нейчев,
e-mail: [email protected]; tel: +359 2 979 3158
Гл. асистент Цветанка Стефанова, [email protected]
Ветеринарен лекар д-р Петя Стоянова, [email protected]
tel: +359 2 979 3158
Вивариум и работа с лабораторни животни
Ръководител: Ветеринарен лекар д-р Петя Стоянова, [email protected]
tel: +359 2 979 3158
ПРОЕКТИ
1.
ФНИ* ДДВУ 02/34 (2011-2014): Функционално подтискане на автореактивни Т клетки чрез
антитялова терапия при миши и хуманизирани SCID модели на системен лупус
еритематозус и множествена склероза. Ръководител: Доц. Андрей Чорбанов.
2.
ACIP A_05/11 (2011-2013): Роля на неутрофилите и NK клетките в развитието на
колагеназа-индуциран остеоартрит. Ръководител: Доц. Петя Димитрова, Колаборатори:
Prof. Angela Santoni, University La Sapienza-Rome/ Dr. Crina Stavaru, Cantacuzino InstituteBucharest, Romania.
3.
ФНИ Рила 013 (2011-2012): Индуциране на толерантност към фактор VIII при хемофилия
А. Ръководител: Доц. Анастас Пашов. Колаборатори: Dr. Sebastien Lacroix-Desmazes,
U872(Eq16) INSERM, Paris, France.
4.
PIRG05-GA-2009-248289 (2010-2013): Транслиращо сравнително изследване на антиген
представящи свойства на субпопулации от човешки и миши В лимфоцити. Доц. Анастас
Пашов.
5.
ФНИ ДТК 02/19 (2010-2013): ДНК ваксини: насочване на вирусни антигени чрез генетичноконструирани химерни молекули. Ръководител: Доц. Андрей Чорбанов.
6.
ФНИ ДТК 02/78 (2010-2013): Антитуморна активност на хемоцианини от гастроподни
организми. Ръководител: Доц. Андрей Чорбанов.
7.
ЕБР/БАН България-Унгария (2010-2012): ДНК ваксини: насочване на вирусни антигени
чрез генетично- конструирани химерни молекули. Ръководител: Доц. Андрей Чорбанов.
Колаборатори: Jozsef Prechl, University Eötvös Lorand, Budapest, Hungary.
8.
ФНИ ДРНФ 02/11 (2009-2012): Биологичен отговор на неопластични и автоимунни В
клетки към протеин-генерирани химерни антитела: флоуцитометричен анализ на
апоптоза чрез нови цианинови багрила за нуклеинови киселини. Ръководител: Доц. Петя
Димитрова, Колаборатори: Доц. Георги Балаценки, СБАЛ по Хематология, София/Проф.
Тодор Делигеоргиев, Химически Факултет, Софийски Университет.
9.
ФНИ ДО 02-312/08 (2009-2012): Подтискане на алерген-специфични В - клетки при
хуманизирани SCID мишки чрез химерни антитела. Ръководител: Доц. Андрей Чорбанов.
10.
ФНИ ВУ 704/07 (2007-2011): Нов подход за селективно подтискане на автореактивни В
клетки чрез химерно анти-CD35 антитяло. Ръководител: Доц. Андрей Чорбанов.
11.
ФНИ ТК 317/07 (2007-2011): Конструиране на генно-инженерни химерни ДНК молекули
чрез рекомбинантни нано-технологии за специфична терапия на автоимунни болести.
Ръководител: Доц. Андрей Чорбанов.
ФНИ*: Фонд „Научни изследвания”
ПУБЛИКАЦИИ
2011
1.
Belenska L, Dimitrova P, Ivanovska N. Influence of complement depletion on the development of
zymosan-induced arthritis. The Youth Scientific Conference “Kliment`S Days” Conference ProceedingsConference Proceedings, 2011, 1st edition, 2nd book, 15-18, ISSN: 1314-4960.
2.
Dimitrov J, Pashov A, Vassilev T. Antibody polyspecificity – what does it matter? In: Natural Antibodies.
Lutz H. (Editor), Landes Biosciences, Austin, TX, USA, 2011, ISBN: TBA.
3.
Dimitrova P, Ivanovska N. How important are innate immunity cells in osteoarthritis pathology. In:
Osteoarthritis. Book 1. InTech, Rijeka, Croatia, 2011. ISBN: 979-953-307-082-6.
4.
Dimitrova P, Toncheva A, Gyurkovska V, Ivanovska N. Involvement of soluble receptor activator of
nuclear factor-κB ligand (sRANKL) in collagenase-induced murine osteoarthritis and human
osteoarthritis. Rheumatol Int 3, 2011. ISSN: 0172-8172.
5.
Dimitrova P, Vassilev T, Shivarov V. AICDA inhibition or overactivation to eliminate pathological B cell
clones? Arthritis Rheum 63, 2011, 3174-3175. ISSN: 1529-0131.
6.
Dineva J, Vangelov I, Todorova K, Stefanova T, Nikolov G, Gulenova D, Ivanova M. Relationship of nitrate
levels in follicular fluids (FFls) and rate of apoptotic human granulosa luteinized cells (GLCs) with the
COH/IVF outcome. Proceedings Bulgarian Acad Sci 2011, in press. ISSN: 1310-1331.
7.
Djoumerska-Alexieva I, Vassilev V. Enhanced binding polyreactivity of human IgG after acid pH
treatment. Proceedings Bulgarian Acad Sci 64, 2011, 1187-1192. ISSN: 1310-1331.
8.
Gesheva V, Idakieva K, Kerekov N, Nikolova K, Mihaylova N, Doumanova L, Tchorbanov A. Rapana
thomasiana hemocyanin as adjuvant of non-conjugated bacterial and viral proteins. Advances in
Bulgarian Sciences, 2010, 2011, 21-29, ISSN: 1313-2563.
9.
Gesheva V, Idakieva K, Kerekov N, Nikolova K, Mihaylova N, Doumanova L, Tchorbanov A. Marine
gastropod hemocyanins as adjuvants of non-conjugated bacterial and viral proteins. Fish Shellfish
Immunol 30, 2011, 135-142. ISSN: 1050-4648.
10.
Gyurkovska V, Alipieva K, Maciuk A, Dimitrova P, Haas C, Bley T, Georgiev M. Anti-inflammatory activity
of Devil's claw in vitro systems and their active constituents. Food Chemistry 125, 2011, 171-178. ISSN:
0308-8146
11.
Idakieva K, Gesheva V, Mihaylova N, Doumanova L, Tchorbanov A. Rapana thomasiana hemocyanin as a
protein carrier and adjuvant of bacterial and viral vaccines. In: Gastropods: Diversity, Habitat and
Genetics. Bianchi A, Fields J. (Editors). Nova Science Publishers, Inc 2011, ISBN: 978-1-61324-695-5.
12.
Ivanovska N, Dimitrova P. Bone resorption and remodeling in murine collagenase-induced osteoarthritis
after administration of glucosamine. Arthritis Res Ther 16, 2011, R44. ISSN: 1478-6354.
13.
Kaloyanova S, Ivanova I, Tchorbanov A, Dimitrova P, Deligeorgiev T. Synthesis of chloro-substituted
analogs of Thiazole orange - Fluorophores for flow cytometric analyses. J Photochem Photobiol B 103,
2011, 215-221. ISSN: 1011-1344.
14.
Kerekov N, Mihaylova N, Prechl J, Tchorbanov A. Humanized SCID mice models of SLE. Curr Pharm Des
17, 2011, 1261-1266. ISSN: 1381-6128.
15.
Kerekov NS, Mihaylova NM, Grozdev I, Todorov TA, Nikolova M, Baleva M, Nikolova M, Prechl J, Erdei A,
Tchorbanov AI. Elimination of autoreactive B cells in humanized SCID mouse model of SLE. Eur J
Immunol 41, 2011, 3301-3311. ISSN: 1521-4141.
16.
Kostova I, Grigorov P, Balkansky S, Stefanova T. Synthesis, characterization and cytotoxicity of newHo(III)
and Er(III) complexes. Indian J Biotechnology 10, 2011, 387-394. ISSN: 0972-5849.
17.
Mihaylova N, Tchorbanov A. New biotechnology approaches for immunotherapy of autoimmune
diseases. Biotech Biotechnological Equipment 25, 2011, 24-29. ISSN: 1310-2818.
18.
Mihaylova N, Tchorbanov A. Selective Immunotherapy by engineered chimeric molecules. Acta
Facultatis Medicae Naissensis 28, 2011, 5-15. ISSN: 0351-6083.
19.
Milanova V, Ivanovska N, Dimitrova P. Neutrophils in zymosan-induced arthritis: the source of proinflammatory cytokines. The Youth Scientific Conference “Kliment`S Days” Conference
Proceedings 2011, 1st edition, 2nd book, 61-64, ISSN: 1314-4960.
20.
Milanova V, Toncheva A, Ivanovska N, Dimitrova P. IL-17 and neutrophils in the pathology of rheumatoid
arthritis. Rheumatology (Sofia) 1, 2011, 37-45. ISSN: 1310-0505.
21.
Milanova V, Toncheva A, Ivanovska N, Dimitrova P. The significance of animal models of rheumatoid
arthritis. Rheumatology (Sofia) 3, 2011, 47-54. ISSN: 1310-0505.
22.
Nikolova K, Gesheva V, Vassilev T. Novel therapeutic approach prevents splenomegaly in lupus-prone
mice with an apoptosis defect. Proceedings Bulgarian Acad Sci 64, 2011, 241-246, ISSN: 1312-2436.
23.
Pashov A, Delignat S, Bayry J, Kaveri SV. Enhancement of the affinity of glucocorticoid receptors as a
mechanism underlying the steroid-sparing effect of intravenous immunoglobulin. J Rheumatol 38, 2011,
2275. ISSN: 0315-162X.
24.
Pashov A, Monzavi-Karbassi B, Kieber-Emmons T. Glycan mediated immune responses to tumor cells.
Hum Vaccine, 7, 2011, 156-165. ISSN: 2164-5515.
25.
Pavlovic S, Zdravkovic N, Dimitrov J, Djukic A, Arsenijevic N, Vassilev T, Lukic M. Intravenous
immunoglobulins exposed to heme (heme IVIG) are more efficient than IVIG in attenuating autoimmune
diabetes. Clin Immunol 138, 2011, 162-171. ISSN: 1521-6616.
26.
Saha S, Pashov A, Monzavi-Karbassi B, Kieber-Emmons AM, Otaki A, Murali R, Kieber- Emmons T.
Carbohydrate Mimetic Peptide. In: Vaccines Anticarbohydrate Antibodies. Kosma P., Müller-Loennies S
(Editors). Springer, Vienna, 2011, 229-254, ISBN: 3709108691.
27.
Stefanova T, Nikolova N, Neychev H, Zlabinger G. Phagocytosis and killing of Salmonella by 7-
hydroxycoumarin activated macrophages. Immunol Invest 2011. DOI:10.3109/08820139.2011.619021.
ISSN: 0882-0139.
28.
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