CURRICULUM VITAE Name : Doo Hyun Nam Sex : Male Present Address : Saweol Bosung Town # 102-1105, Saweol-dong, Suseong-gu, Taegu Korea (Tel) 82-53-791-2083 Date of Birth : September 22, 1953 Major Field : Applied Microbiology and Bacterial Genetics Educational Background : 1972 - 1976 College of Pharmacy, Yeungnam University (B.S.) 1976 - 1978 Department of Biological Science and Engineering Korea Advanced Institute of Science (M.S.) 1980 - 1984 Department of Biological Science and Engineering Korea Advanced Institute of Science and Technology (Ph.D.) (Dissertation Title) Kinetic Analysis in Enzymatic Synthesizing Enzyme Systems of Semisynthetic ß-Lactam Antibiotics 1986.6. Workshop on Molecular Biology and Genetics of Streptomyces Waksman Institute of Microbiology Continuing Professional Education, Rutgers University, NJ 08854, U.S.A. Professional Experiences : 1978 - 1980 Scientific Researcher Korea Research Institute of Chemical Technology 1980 - 1984 Teaching and Research Assistant Korea Advanced institute of Science and Technology 1984 - 1989 Senior Researcher, Genetic Engineering Research Center 1985 - 1986 Visiting Scientist The Beckman Research Institute of the City of Hope Duarte, CA 91010, U.S.A. 1986 - 1987 Research Associate , University of California, Davis CA 95616, U.S.A. 1989 - 1993 Assistant Professor, College of Pharmacy, Yeungnam University 1989 - 1990 Visiting Professor, University of California / Davis 1993 - 1998 Assocate Professor, College of Pharmacy, Yeungnam University 1993 – 1995 Chair, Department of Industrial Pharmacy, Yeungnam University 1993 – 1995 Secretary, Institute for Drug Research, Yeungnam University 1995 – 1997 Vice Dean, College of Pharmacy, Yeungnam University 1997 - 1999 Visiting Professor, University of California / Davis 1998 – 2019 Professor, College of Pharmacy, Yeungnam University 1999 – 2000 Secretary, Institute of Biotechnology, Yeungnam University 2000 - 2002 Director, Institute of Biotechnology, Yeungnam University 2002 – 2004 Dean, College of Pharmacy, Yeungnam University 2002 – 2004 2004 – 2004 Membership : 1989-present 1989-present 1991-present 1992-present 1992-present 1993-present 1993-present Director, Institute of Drug Development, Yeungnam University Dean, Graduate School of Clinical Pharmacy, Yeungnam University Member, The American Society for Microbiology Member, The Korean Society for Molecular Biology Councilor, The Biochemical Society of the Republic of Korea Councilor, The Korean Society for Applied Microbiology Councilor, The Phramaceutical Society of Korea Councilor, The Microbiological Society of Korea Councilor, The Korean Society for Biotechnology and Bioengineering Academic Services : 1994-1995 Organizing Secretary, The Korean Society for Biotechnology and Bioengineering 1996-1996 Committee Member, Academy-Industry Cooperation Committee, The Korean Society for Applied Microbiology 2001-2002 Auditor, The Biochemical Society of the Republic of Korea 2001-2002 Executive Organization Committee Member, GIM-2002 (the 9th International Symposium on Genetics of Industrial Micro-organisms) 2003-2003 Chief-in-Editor, Journal of Microbiology, The Microbiological Society of Korea 2003-2003 Division Chair of Microbiology and Immunology, The Phramaceutical Society of Korea 2003-2004 Yeungnam Regional Chair, The Phramaceutical Society of Korea 2003-2004 Vice-President, The Phramaceutical Society of Korea 2003-2006 Taegu-Kyungbuk Regional Chair, The Korean Society for Biotechnology and Bioengineering 2004-2004 Auditor, The Microbiological Society of Korea 2005-2005 Vice-President, The Microbiological Society of Korea 2005-2005 Vice-President, The Korean Society for Biotechnology and Bioengineering 2005-2005 Organizing Committee Member, Enzyme Engineering XVIII, Engineering Conference International (ECI) 2006-2006 Executive Chief of Secretary, The Microbiological Society of Korea 2007-2010 Trustee, The Korean Society for Biochemistry and Molecular Biology 2008-2008 Trustee, The Microbiological Society of Korea 2009-2009 Vice-President, The Microbiological Society of Korea 2009-2010 Auditor, The Korean Society for Biotechnology and Bioengineering 2010-2010 President Elect, The Microbiological Society of Korea 2011-2011 President, The Microbiological Society of Korea 2012-2013 Trustee, The Microbiological Society of Korea 2013-2013 Auditor, The Korean Society for Microbiology and Biotechnology Community Services : 1999-2001 Advisory Board Member, Korea Technology Assessment Co., Ltd 2004-2006 Member, Medical Review and Assessment Committee, Health Insurance 2005-2007 2005-2009 2006-2009 2006-2009 2011-2011 2011-2011 Review and Assessment Service Member, National Antibiotic Resistance Surveillance Committee, Korea Center for Disease Control and Prevention Steering Committee Member, New Technology Agency, Daegu-TechnoPark Member, Safety Management Committee for Food Intoxication, Daegu Regional Food and Drug Administration Advisory Board Member, Traditional Bio-Materials Industry Center, DaeguTechnoPark Member, Experts’ Forum Facing Nagoya Protocol, Ministry of Environment. Member, Committee for the Promotion of Academic Activities, The Korean Federation of Science and Technology Societies Awards : 1976. 2. President Award (B.S. Graduation), Yeungnam University (Korea) 2003. 2. Nam-Yang Aloe Academic Award in Biopharmaceutical Research (Korea) 2003. 10. Commendatory Honor of Commissioner of Korea Food and Drug Administration (Korea) Technical Publications (Since 2000) 1. D. H. Nam and D. D. Y. Ryu Preparation of 6-aminopenicillanic acid using penicillin amidohydrolase from Micrococcus luteus J. Ferment. Technol., 57(2), 141-145 (1979) (Japan) 2. D. H. Nam and D. D. Y. Ryu Biochemical properties of penicillin amidohydrolase from Micrococcus luteus Appl. Environ. Microbiol., 38(1), 35-38 (1979) (U.S.A.) 3. D. H. Nam and D. D. Y. Ryu Differential analysis of amikacin and butirosin Arch. Pharm. Res., 5(2), 87-91 (1982) (Korea) 4. D. H. Nam, H. S. Sohn, and D. D. Y. Ryu Enzymatic synthesis of cephaloglycin Bull. Korean Chem. Soc., 4(2), 72-76 (1983) (Korea) 5. I. H. Kim, D. H. Nam, and D. D. Y. Ryu Cephalexin synthesis using immobilized Xanthomonas citri cells Appl. Biochem. Biotechnol., 8(3), 195-202 (1983) (U.S.A.) 6. D. H. Nam and J. H. Kim Purification and properties of -glucosidase from Sporotrichum cellulophilum Korean J. Appl. Microbiol. Bioeng., 12(1), 21-26 (1984) (Korea) 7. D. H. Nam and D. D. Y. Ryu Enzymatic synthesis of phenoxymethylpenicillin using Erwinia aroideae enzyme J. Antibiot., 37(10), 1217-1223 (1984) (Japan) 8. D. H. Nam and D. D. Y. Ryu Synthesis of phenoxymethylpenicillin using α-acylamino-β-lactam acylhydrolase from Erwinia aroideae Ann. N. Y. Acad. Sci., 434(Enzyme Engineering 7), 210-213 (1984) (U.S.A.) 9. D. H. Nam, C.S. Lee and D. D. Y. Ryu An improved synthesis of captopril J. Pharm. Sci., 73(12), 1843-1844 (1984) (U.S.A.) - cited in Merck Index 10. D. H. Nam and D. D. Y. Ryu Relationship between butirosin biosynthesis and sporulation in Bacillus circulans Antimicrob. Ag. Chemother., 27(5), 798-801 (1985) (U.S.A.) 11. D. H. Nam, C. Kim, and D. D. Y. Ryu Reaction kinetics of cephalexin synthesizing enzyme from Xanthomonas citri Biotechnol. Bioeng., 27(7), 953-960 (1985) (U.S.A.) 12. N. Y. Hur, D. H. Oh, J. H. Yu, D. H. Nam, and J. H. Kim Purification and reaction characteristics of ampicillin acylase from Pseudomonas melanogenum Korean J. Appl. Microbiol. Bioeng., 15(1), 9-14 (1987) (Korea) 13. D. H. Nam and D. D. Y. Ryu Molecular cloning of the gene for α-acylamino-β-lactam acylhydrolase from Acetobacter turbidans by immunochemical detection method Korean J. Appl. Microbiol. Bioeng., 16(5), 363-368 (1988) (Korea) 14. D. H. Nam, D. D. Y. Ryu, D. Ogrydziak, and F. Farahnak Cloning and characterization of the β-galactosidase gene from Kluyveromyces fragilis Proc. Asia-Pacific Biochem. Eng. Conf. 1990, 314-317 (1990) (Korea) 15. J. W. Roh, J. H. Bang, and D. H. Nam Nutritional requirement for the production of cephabacins by Lysobacter lactamgenus Biotechnol. Letter, 14(6), 455-460 (1992) (U.K.) 16. C. H. Lee, S. A. Yang, J. W. Roh, S. Y. Lee, and D. H. Nam Ethanol fermentation in lactose medium using a fusant strain of Saccharomyces cerevisiae and Kluyveromyces fragilis J. Microbiol. Biotechnol., 2(2), 108-114 (1992) (Korea) 17. J. W. Roh and D. H. Nam Biosynthesis of β-lactam antibiotics by cell-free extract from Lysobacter lactamgenus Arch. Pharm. Res., 15(3), 234-238 (1992) (Korea) 18. C. H. Lee, J. H. Bang, and D. H. Nam Ethanol production from lactose by immobilized yeast reactor of a fusant strain of Saccharomyces cerevisiae and Kluyveromyces fragilis Korean J. Microbiol., 30(4), 355-359 (1992) (Korea) 19. S. Y. Yang and D. H. Nam Purification and characterization of α-amino acid ester hydrolase from Xanthomonas citri J. Resource Develop. (Yeungnam Univ.), 12(1), 81-87 (1993) (Korea) 20. S. Y. Lee, D. H. Nam, and T. Chung The role of AP-1 binding sites on the regulation of transcriptional activity by LTR sequences of human foamy virus (Ⅰ). Construction of AP-1 mutants by site-directed mutagenesis Basic Sci. Res. (Yeungnam Univ.), 12(1), 319-328 (1993) (Korea) 21. D. H. Nam, J. H. Ko and S. Y. Lee Design and cloning of the gene for a novel insulin analogue, (B30-homoserine) human insulin Arch. Pharm. Res., 16(4), 271-275 (1993) (Korea) 22. D. H. Nam, J. H. Ko and S. Y. Lee Cloning of the gene for a novel insulin analogue, (B30-homoserine) human insulin and its production in Escherichia coli Merging Pharmaceutics with Biopharmacy, 29-37 (1993) (Korea) 23. C. H. Lee, D. H. Nam, and K. Huh Molecular cloning of xanthine oxidase gene from mouse cDNA library J. Resource Develop. (Yeungnam Univ.), 13(1), 45-51 (1994) (Korea) 24. C. H. Lee, D. H. Nam, and K. Huh An active monomeric form of bovine milk xanthine oxidase Arch. Pharm. Res., 17(5), 318-322 (1994) (Korea) 25. J. H. Bang, D. H. Nam, D. O. Kang, J. S. Ahn, and D. D. Y. Ryu Cloning and expression of Kluyveromyces fragilis β-galactosidase gene in Saccharomyces cerevisiae J. Microbiol. Biotechnol., 5(1), 6-13 (1995) (Korea) 26. C. S. Yong, D. H. Nam and K. Huh Comparison of Cu(II)-DIPS and human recombinant superoxide dismutase, an antioxidant J. Korean Pharm. Sci., 25(2), 145-152 (1995) (Korea) 27. J. M. Kim, K. Huh, and D. H. Nam Oxygen toxicity of superoxide dismutase-deficient Sacchromyces cerevisiae by Paraquat Kor. J. Biotechnol. Bioeng., 10(5), 561-567 (1995) (Korea) 28. J. K. Lee, J. M. Kim. S. W. Kim, C. S. Yong, K. Huh, and D. H. Nam Effect of copper ion on oxygen damage in superoxide dismutase-deficient Sacchromyces cerevisiae Arch. Pharm. Res., 19(3), 178-182 (1996) (Korea) 29. S. Y. Lee, M. H. Choi, and D. H. Nam Fermentation of LacZ-fused single chain insulin precursor for (B30-homoserine) human insulin Biotechnol. Bioprocess Eng., 1(1), 9-12 (1996) (Korea) 30. M. H. Choi, M. K. Hong, and D. H. Nam Molecular cloning of isopenicillin N synthetase gene from Streptomyces clavuligerus and its expression in Escherichia coli J. Resource Develop. (Yeungnam Univ.), 16(1), 72-77 (1997) (Korea) 31. M. J. Kim, S. W. Kim, and D. H. Nam Immunochemical reactivity of polyclonal antibody against ampicillin acylase of Xanthomonas citri J. Microbiol. Biotechnol., 7(3), 194-196 (1997) (Korea) 32. J. K. Ryu and D. H. Nam Cloning of isopenicillin N synthase gene from Lysobacter lactamgenus J. Microbiol. Biotechnol., 7(6), 373-377 (1997) (Korea) 33. S. M. Lee and D. H. Nam Anaerobic respiration of superoxide dismutase-deficient Saccharomyces cerevisiae under oxidative stresses Biotechnol. Bioprocess Eng. 3(2), 15-18 (1998) (Korea) 34. S.Y. Chang, S.J. Kang, Y.J. Jung, J.H. Shin, J.H. Kim, K.W. Ha , D.H. Nam, and H.J. Kim Quality evaluation of animal crude drug. (I) Quality evaluation and identification of Cervi Parvum Cornu by molecular biological technique. Ann. Rep. KFDA, 3, 275-281 (1999) (Korea) 35. S.Y. Chang, R.S. Sung, D.H. Kim, Y.J. Jung, J.P. Lee, C.K. Lee, K.W. Ha, H.J. Kim, and D.H. Nam Quality evaluation of animal crude drug. (II) Quality evaluation and analysis of Cervi Parvum Cornu by near IR spectrum. Ann. Rep. KFDA, 3, 282-286 (1999) (Korea) 36. J.S. Yeo, J. S. Lee, C. H. Lee, Y. J. Jung, and D. H. Nam Identification of genetic markers for Korean native cattle (Hanwoo) by RAPD analysis Biotechnol. Bioprocess Eng. 5(1), 23-16 (2000) (Korea) 37. J. S. Lee, C. H. Lee, D. H. Nam, Y. J. Jung, and J. S. Yeo A genetic marker for the Korean native cattle (Hanwoo) found by an arbitrarily primedpolymerase chain reaction (AP-PCR) J. Biochem. Mol. Biol., 33(3), 208-212 (2000) (Korea) -SCIE 38. Y. S. Lee, D. H. Nam, and J. A. Kim Induction of apoptosis by capsaicin in A172 human glioblastoma cells Cancer Lett., 161, 121-130 (2000) (Netherland) –SCI 39. H. S. Lee, H.Y. Lee, H.K. Gu, S.S. Han, C.-H. Yun, J.H. Kim, J.-A. Kim, E.-S. Lee, D.-H. Nam, and T.C. Jeong Effects of flupyrazofos on liver microsomal cytochrome P450 in the male Fisher 344 rat Xenobiotica, 30(12), 1123-1130 (2000) (United Kingdom) -SCI 40. D. H. Nam, S. K. Lim, M. H. Chung, E. S. Lee, Y. S. Sohn, and D. D. Y. Ryu Membrane transporter genes in cephabacin biosynthetic gene cluster of Lysobacter lactamgenus J. Microbiol. Biotechnol., 11(1), 153-159 (2001) (Korea) -SCI 41. E. J. Kim, Y. J. Jung, S. J. Kang, S. Y. Chang, D. H. Nam, and K. Huh Molecular discrimination of Cervidae antlers and Rangifer antlers J. Biochem. Mol. Biol., 34(2), 114-117 (2001) (Korea) -SCIE 42. D .H. Nam, Y. W. Ryu, and D. D. Y. Ryu pH-controlled synthesis of cephalexin by a purified Acetobacter turbidans ampicillin acylase J. Microbiol. Biotechnol., 11(2), 329-332 (2001) (Korea) -SCI 43. J. W. Cho, S. H. Park, and D. H. Nam Production and purification of single chain human insulin precursors with various fusion peptides Biotechnol. Bioprocess Eng. 6(2), 144-149 (2001) (Korea) 44. S. W. Cha, H. J. Lee, M. H. Cho, M. H. Lee, W. S. Koh, S.-S. Han, J.-A. Kim, E. S. Lee, D. H. Nam, and T. C. Jeong. Role of corticosterone in ethyl carbamate-induced immunosuppression in female BALB/c mice Toxicol. Lett., 119, 173-181 (2001) (Netherland) -SCI 45. H. S. Chang, Y. K. Bae, S. K. Lim, T. C. Jeong, H. S. Kim, S. T. Chung, D. S. Kim and D. H. Nam Allergenicity test of genetically modified soybean in Sprague Dawley rats Arch. Pharm. Res., 24(3), 256-261 (2001) (Korea) –SCIE 46. Y. S. Sohn, D. H. Nam, and D. D. Y. Ryu Biosynthetic pathway of cephabacins in Lysobacter lactamgenus: molecular and biochemical characterization of the upstream region of the gene clusters for engineering of novel antibiotics. Metabol. Eng., 3(5), 380-392 (2001) (U.S.A.) 47. S. K. Lim, J. W. Choi, E. T. Lee, Y. H. Khang, S. D. Kim, and D. H. Nam Isolation of Streptomyces sp. YU100 producing extracellular phospholipase D. J. Microbiol. Biotechnol., 12(1), 71-76 (2002) (Korea) –SCI 48. S. K. Lim, J. W. Choi, M. H. Chung, E. T. Lee, Y. H. Khang, S. D. Kim, and D. H. Nam Production and characterization of extracellular phospholipase D from Streptomyces sp. YU100. J. Microbiol. Biotechnol., 12(2), 189-195 (2002) (Korea) –SCI 49. J. S. Yeo, J. W. Kim, T. K. Chang, D. H. Nam, J. Y. Han, and C. B. Choi Detection of DNA fragment to differentiate Korean cattle. Asian-Aust. J. Anim. Sci., 15(8), 1071-1075 (2002) (Australia) –SCIE 50. Y. S. Lee, D.-Q. Jin, E. J. Kwon, S. H. Park, E.-S. Lee, T. C. Jeong, D. H. Nam, K. Huh and J.A. Kim Asiatic acid, a triterpene, induces apoptosis through intracellular Ca2+ release and enhances expression of p53 in HepG2 human hepatoma cells Cancer Lett.. 186(1) 83-91 (2002) (Netherland) –SCI 51. H. S. Chang, N. H. Kim, M. J. Park, S. K. Lim, S. C. Kim, J. Y. Kim, C. H. Lee, J. A. Kim, H. Y. Oh, K. Huh, T. C. Jeong and D. H. Nam The 5-enolpyruvylshikimate-3-phosphate synthase of glyphosate-tolerant soybean expressed in Escherichia coli shows no severe allergenicity Mol. Cells, 15(1), 20-26 (2003) (Korea) – SCI 52. S. C. Kim, J. W. Lee, A. Yoo, H. S. Chang, K. H. Lee, J. M. Park and D. H. Nam. Bioequivalence assessment of domperidone maleate tablets in healthy Korean volunteers. J. Appl. Pharmacol., 11(2), 145-150 (2003) (Korea) 53. E.-T. Lee, S.-K. Lim, D.-H. Nam, Y.-H. Khang, and S.-D. Kim Pyoverdin2112 of Pseudomonas fluorescens 2112 inhibits Phytophthora capsici, a red-pepper blight-causing fungus. J. Microbiol. Biotechnol., 13(3), 415-421 (2003) (Korea) –SCI 54. A. Yoo, S. C. Kim, K. H. Lee, J. M. Park and D. H. Nam. Bioequivalence assessment of Shinpoong Dompil tablets containing 12.72mg of domperidone maleate. J. Kor. Soc. Health-Sys. Pharm.., 20(4), 465-473 (2003) (Korea) 55. J. H. Cho, D. H. Kim, M. H. Oh, Y. H. Shim, E. K. Kim, J. H. Kim, D. H. Kim, S. K. Jee, C. D. Park, H. J. Kim and D .H. Nam Establishment of identification method for natural herbs and their preparations by molecular biological technique. Ann. Rep. KFDA, 7, 552-556 (2003) (Korea) 56. J.-K. Sohng, H.-J. Kim, D.-H. Nam, D.-O. Lim, J.-M. Han, H.-J. Lee, and J.-C. Yoo Cloning, expression, and biological function of a dTDP-deoxyglucose epimerase (gerF) gene from Streptomyces sp. GERI-155 Biotechnol. Letter, 26(3), 185-191 (2004) (U.K.) –SCI 57. H.-C. Lee, J.-K. Sohng, H.-J. Kim, D.-H. Nam, J.-M. Han, S.-S. Cho, J.-H. Choi and J.-C. Yoo Cloning and expression of the glucose-1-phosphate thymidylyltransferase gene (gerD) from Streptomyces sp. GERI-155 Mol. Cells 17(2), 274-280 (2004) (Korea) – SCI 58. H. Lee, J. Sohng, H. Kim, D. Nam, C. Seong, J. Han, and J. Yoo Cloning, expression, and biochemical characterization of dTDP-glucose 4,6-dehydratase gene (gerE) from Streptomyces sp. GERI-155 J. Microbiol. Biotechnol., 14(3), 576-583 (2004) (Korea) –SCI 59. M. J. Park, J. O. Yon, S. K. Lim, D. D. Y. Ryu, D. H. Nam Biochemical characterization of an ABC transporter gene involved in cephabacin biosynthesis in Lysobacter lactamgenus. J. Microbiol. Biotechnol., 14(3), 635-638 (2004) (Korea) –SCI 60. Y.-S. Jeong, H.-J. You, S.-D. Kim, D.-H. Nam, and K.-Y. Khang Cloning and sequencing of a novel glutaryl acylase β-subunit gene of a Pseudomonas cepacia BY21 from bioinformatics Biotechnol. Bioprocess Eng. 10(6), 510-515 (2005) (Korea)-SCIE 61. A. V. Demirev, C.-H. Lee, B. P. Jaishy, D.–H. Nam, and D. D.Y. Ryu Substrate specificity of nonribosomal peptide synthetase modules responsible for the Biosynthesis of oligopeptide moiety in cephabacin by Lysobacter lactamgenus FEMS Microbiol. Letters, 255, 121-128 (2006) (Netherland) –SCI 62. J. S. Lee, M. O. Lim, K. Y. Cho, J. H. Cho, S. Y. Chang, and D. H. Nam Molecular discrimination of medicinal mushrooms based on nuclear large subunit rDNA sequences J. Microbiol., 44(1), 29-34 (2006) (Korea) –SCIE 63. D. H. Nam, K. H. Son, J. Y. Kim, S. D. Kim, and S. K. Lim Quantitative determination of dioscin from Dioscorea rhizoma Kor. J. Pharmacogn., 37(1), 33-36 (2006) (Korea) 64. J. R. Jeon, J. S. Lee, C. H. Lee, J. Y. Kim, S. D. Kim and D. H. Nam Effect of ethanol extract of dried Chinese yam (Dioscorea batatas) flour containing dioscin on gastrointestinal function in rat model Arch. Pharm. Res., 29(5), 348-353 (2006) (Korea) –SCIE 65. B. P. Jaishy, S. K. Lim, I. D. Yoo, J. C. Yoo, J. K. Sohng, and D. H. Nam Cloning and Characterization of a gene cluster for the production of the polyketide macrolide dihydrochalcomycin in Streptomyces sp. GERI-155 J. Microbiol. Biotechnol., 16(5), 764-770 (2006) (Korea) –SCI 66. K. O. Shin, J. R. Jeon, J. S. Lee, J. Y.Kim, C. H. Lee, S. D. Kim, Y.-S. Yu and D. H. Nam Lactic acid fermentation of Chinese yam (Dioscorea batatas Decne) flour and its pharmacological effect on gastrointestinal function in rat model Biotechnol. Bioprocess Eng., 11(3), 240-244 (2006) (Korea) –SCIE 67. M. O. Lim, W. Yin, J. S. Lee, Y. S. Yu, S. D. Kim, and and D. H. Nam Effect of medium components on the lipstatin production by Streptomyces toxytricini Kor. J. Microbiol., 42(3), 172-176 (2006) (Korea) 68. A. Yoo, A.V. Demirev, J.S. Lee, S.D. Kim, and D.H. Nam Cloning and analysis of type II polyketide synthase gene cluster from Streptomyces toxytricini NRRL 15,443 J. Microbiol., 44(6), 649-654 (2006) (Korea) –SCIE 69. T.T.T. Thuy, K. Liou, T.J. Oh, D.H. Kim, D.H. Nam, J.C. Yoo, and J.K. Sohng Biosynthesis of dTDP-6-deoxy-β-D-allose, biochemical characterization of dTDP-4-keto-6deoxyglucose reductase (GerK1) from Streptomyces sp. KCTC 0041BP. Glycobiology, 17(2), 119-126 (2007) (U.K.) - SCI 70. S.K. Lee, D.J. Lee, H. Jeong, S.R. Bista, M.J. Kang, E.S. Lee, J.K. Sohn, D.H. Nam, H.W. Chang, S.H. Lee, Y. Jahng, and T.C. Jeong Hepatotoxic and immunotoxic effects produced by 1,3-dibromopropane and its conjugation with glutathione in female BALB/c mice J. Toxicol. Eniviron. Health Part A, 70(15) (USA), 1381-1390 (2007) – SCI 71. H.K. Jung, J.H. Hong, S.C. Park, B.K. Park, D.H. Nam, and S.D. Kim Production and physicochemical characterization of -glucan produced by Paenibacillus polymyxa JB115 Biotechnol. Bioprocess Eng., 12(6), 713-719 (2007) (Korea) –SCIE 72. J. O. Yon, J. S. Lee, B. G. Kim, S. D. Kim and D. H. Nam Immobilization of Streptomyces phospholipase D on a Dowex macroporous resin Biotechnol. Bioprocess Eng., 13(1), 102-107 (2008) (Korea) –SCIE 73. H. K. Jung, S. C. Park, B. K. Park, S. D. Kim, D. H. Nam and J. H. Hong, Characteristics of the antibacterial substance produced by Paenibacillus polymyxa JB115 Kor. J. Biotechnol. Bioeng., 23(1), 65-69 (2008) (Korea) 74. J.S. Lee, M. G. Vladimirova, A. V. Demirev, B. G. Kim, S. K. Lim, and D. H. Nam Expression and characterization of polyketide synthase module involved in the late step of cephabacin biosynthesis from Lysobacter lactamgenus J. Microbiol. Biotechnol., 18(3), 427-433 (2008) (Korea) –SCIE 75. H.W. Jo, S.H. Lee, D.H. Nam, J.Y. Kim, S.K. Lim, J.S. Lee, and J.C. Park Antioxidant activity and phytochemical study on the aerial parts of Oenanthe javanica Kor. J. Pharmacogn., 39(2), 142-145 (2008) (Korea) 76. J.C. Park, J.Y. Kim, Y.J. Lee, J.S. Lee, B.G. Kim, S.H. Lee, and D.H. Nam Protective effect of Oenanthe javanica extract on acetaminophen-induced hepatotoxicity in rats J. Korean Pharm. Sci. (Yakhak Hoeji), 52(4) 316-321 (2008) (Korea). 77. J.S. Lee, M. Bat-Ochir, A.V. Demirev, and D.H. Nam Molecular cloning of the phospholipase D gene from Streptomyces sp. YU100 and its expression in Escherichia coli J. Microbiol., 47(1), 116-122 (2009) (Korea) –SCIE 78. A. V. Demirev, J. S. Lee, B. R. Sedai, I. G. Ivanov, and D. H. Nam Identification and characterization of acetyl-CoA carboxylase gene cluster in Streptomyces toxytricini J. Microbiol., 47(4), 473-478 (2009) (Korea) –SCIE 79. J. Y. Kim, K.-H. Kim, Y. J. Lee, S. H. Lee, J. C. Park, and D. H. Nam Oenanthe javanica extract accelerates ethanol metabolism in ethanol-treated animals BMB Reports 42(8), 482-485 (2009) (Korea) –SCIE 80. A. V. Demirev, A. Khanal, B. R. Sedai, S. K. Lim, M. K. Na and D. H. Nam The role of acyl-coenzyme A carboxylase complex in lipstatin biosynthesis of Streptomyces toxytricini Appl. Microbiol. Biotechnol., 87, 1129-1139 (2010) (Netherland) –SCI 81. S. C. Kim, Y. C. Park, B. G. Kim, and D. H. Nam Outpatient antibiotic prescription by pediatric and ENT physicians in Ulsan city Kor. J. Clin. Pharm, 20(2), 145-150 (2010) (Korea) 82. S. C. Kim, Y. R. Kim, J. Y. Hwang, H. W. Chang, and D. H. Nam Outpatient prescription pattern of anti-inflammatory drugs by pediatricians and ENT physicians in Ulsan city Kor. J. Clin. Pharm, 20(3), 205-212 (2010) (Korea) 83. D. H. Nam, S. Y. Park, J. M. Park, and S. C. Kim Therapeutic and cost effectiveness of proton pump inhibitor regimens for idiopathic and druginduced peptic ulcer complication Arch. Pharm. Res., 34(2), 443-449 (2011) (Korea) –SCIE 84. A.V. Demirev, A. Khanal, N.G.K Hanh, K.T. Nam and D.H. Nam Biochemical characterization of propionyl-coenzyme A carboxylase complex of Streptomyces toxytricini J. Microbiol., 49(3), 407-412 (2011) (Korea) –SCIE 85. J. H. Kim, S. G. Jin, S. K. Ku, .D. H. Nam, Y. T. Sohn, D. S. Ryu, E.-S. Do, S. W. Jang, M. W. Son, C. S. Yong, H.-G. Choi, and J. O. Kim Wound Healing Evaluation of Benzalkonium Chloride-Loaded Hydrocolloid in the Wound Infection Model J. Pharm. Invest. 42. 327–333 (2012) (Korea) 86. B.R. Park and D. H. Nam Strategy against Nagoya Protocol in the Field of Food, Drug and Cosmetic Industry Reg. Res. Food Drug Cosmet, 7, 69-81 (2012) (Korea) 87. D. H. Nam, J. Y. Yoon. M. W. Cho and H. J. Kim The Registry of Biopharmaceutical Drugs in the Korean Official Compendium Reg. Res. Food Drug Cosmet,7, 91-102 (2012) (Korea) Technical Reviews : 1. D. D. Y. Ryu and D. H. Nam Enzymatic synthesis of semisynthetic β-lactam antibiotics Enzyme Engineering News, 9, 30-62 (1983) (Japan) 2. D. H. Nam and M. H. Han Biochemical transformation of pharmaceutical compounds. Korean Biochem. News, 4(2), 62-75; 4(3), 55-79 (1984); (Korea) 3. D. H. Nam Molecular cloning of antibiotic-producing microorganisms. Korean Biochem. News, 7(3), 51-60 (1987) (Korea) 4. D. H. Nam Biotechnology in pharmaceutical industry Koreran Biochem. Eng., 5(1), 41-45 (1991) (Korea) 5. D. H. Nam Biosynthetic pathway of β-lactam antibiotics Pharmacon, 21(3), 352-362 (1991) (Korea) 6. D. H. Nam Free Radical Scavenger - Superoxide Dismutase Korean Pharmacist J., 2(3), 121-127 (1991) (Korea) 7. D. H. Nam Gene cloning in streptomycetes and its application Recent Trends in Bioprocess Development (Ed. by H. N. Chang), 1, 66-89, Bioprocess Engineering Research Center, Daejeon (1992) (Korea) 8. D. H. Nam Biosynthetic genes for β-lactam antibiotics Korean Mol. Biol. News, 4(2), 38-50 (1992) (Korea) 9. D. H. Nam Antibiotic fermentation by streptomycetes Microorg. Industry., 18(3), 63-68 (1992) (Korea) 10. D. H. Nam and D. D. Y. Ryu Biomolecular engineering and drug development Biotechnol. Bioprocess Eng., 4(2), 83-92 (1999) (Korea) 11. D. D. Y. Ryu and D. H. Nam Recent progress in biomolecular engineering Biotechnol. Progr., 16(1), 2-16 (2000) (U.S.A.) -SCI 12. J.S. Yeo, J.W. Kim, T.-K. Chang, Y.A. Park and D. H. Nam Utilization of DNA marker-assisted selection in Korean native animals Biotechnol. Bioprocess Eng., 5(2), 71-78 (2000) (Korea) 13. D. D. Y. Ryu and D. H. Nam Biomolecular engineering: a new frontier in biotechnology -SCI J. Mol. Catal. B: Enzymatic, 10, 23-37 (2000) (Netherland) 14. J. K. Ryu, H. S. Kim, and and D. H. Nam Current Status and perspectives of Biopharmaceutical Drugs -SCIE Biotechnol. Bioprocess Eng.,17(5), 900-911 (2012) (Korea) Technical Books 1. "Biofuture" (Translation) Edited by B. K. Zimmerman, Translated into Korean by D. H. Nam Published by Ikong Publishing Co., Seoul, Korea (1988) 2. "New Comprehensive Microbiology" (Korean) by Editorial Board of Pharmaceutical Microbiology (K.H. Kim, D.H. Kim, B.K. Kim, S.Y. Kim, D.H. Nam, B.A. Shin, K.H. Moon, Y.K. Ahn, J.H.Yang, J.C. Yoo, K.M. Lee, K.H. Lee, D.K. Rhee, K.S. Chung, K.S. Chung, E.C. Choi, N.J. Ha, and S.S. Han) Published by Hak-Chang-Sa Co., Seoul, Korea (1991) 3. "Laboratories in Comprehensive Microbiology" (Korean) by Editorial Board of Pharmaceutical Microbiology (K.H. Kim, D.H. Kim, B.K. Kim, S.Y. Kim, D.H. Nam, B.A. Shin, K.H. Moon, Y.K. Ahn, J.H.Yang, J.C. Yoo, K.M. Lee, K.H. Lee, D.K. Rhee, K.S. Chung, K.S. Chung, E.C. Choi, N.J. Ha, and S.S. Han) Published by Dae-Hak-Sa Co., Seoul, Korea (1992) 4. "Drug, Health and Environment" (Korean) by Editorial Board in Drug Development Research Institute (K.C. Chung, K. Huh, S.R. Chung, Y.D. Jhang, H.W. Chang, D.H. Nam, and C.S. Yong) Published by Chunwoo-Moonye-Sa, Taegu, Korea (1992) 5. "Antibiotic Paradox" (Translation to Korean) (ISBN 89-7044-562-5) Edited by S. B. Levy, Translated into Korean by D. H. Nam Published by Chonpa-Kwahak-Sa Co., Seoul, Korea (1995) 6. "New Pharmaceutical Microbiology" (Korean) by Editorial Board of Pharmaceutical Microbiology (C.Y. Kang, K.J. Kim, K.H. Kim, K.H. Kim, D.H. Kim, B.K. Kim, J.Y. Kim, H.J. Kim, T.S. Kim, D.H. Nam, K.H. Moon, A.R. Moon, Q.H. Park, M.J. Sim, B.H. Lee, J.H.Yang, J.C. Yu, K.M. Lee, K.H. Lee, D.I. Lee, D.K. Rhee, J.K. Lee, M.H. Lee, K.S. Chung, K.S. Chung, S.S. Choi, E.C. Choi, S.N. Pyo, N.J. Ha, and S.S. Han) Published by Hak-Chang-Sa Co., Seoul, Korea (1999) 7. “Current Laboratory in Microbiology” (Korean) (ISBN 89-85671-78-2) by Editorial Board of Pharmaceutical Microbiology (K.H. Moon, D.H. Kim, M.H. Lee, A.R. Moon, Y. W. Han, K.H. Lee, K.J. Kim, N.J. Ha, C.Y. Kang, S. H. Kim, E.C. Choi, D.K. Rhee, S.N. Pyo, D.H. Nam, J.H.Yang, B.H. Lee, K.H. Kim, K.M. Lee, T.S. Kim, J.C. Yu, K.H. Kim, H.J. Kim, D.I. Lee, K.S. Chung, S. S. Song, and J.K. Lee) Published by Shinil Publishing Co., Seoul, Korea (2001) 8. "Drug and Health" (Korean) (ISBN 89-7581-167-0) by Editorial Board in Drug Development Research Institute (K. Huh, S.R. Chung, Y.D. Jhang, H.W. Chang, D.H. Nam, J. K. Sohn, C.S. Yong, E. S. Lee, S. H. Lee, J.A. Kim, H. K. Choi, and T.C. Jeong) Published by Yeungnam University Press, Taegu, Korea (2002) 9. " New Comprehensive Microbiology" (Korean) (ISBN 978-89-5702-162-0) by Editorial Board of Pharmaceutical Microbiology and Immunology (C.Y. Kang, K.J. Kim, K.H. Kim, D.H. Kim, H.J. Kim, T.S. Kim, D.H. Nam, K.H. Moon, A. Moon, E.H. Son, S.K. Song, M.J. Shim, K.H. Lee, J.Y. Lim, J.C. Yoo, K.M. Lee, D.I. Lee, D.K. Rhee, J.K. Lee, M.H. Lee, M.J. Lim, K.S. Chung, E.C. Choi, S.R. Pyo, N.J. Ha, K.W. Hwang and Y.M. Han) Published by Shinil Publishing Co., Seoul, Korea (2005) 10. “Practice for Pharmaceutical Microbiology” (Korean) (ISBN 978-89-5702-147-7) by Editorial Board of Pharmaceutical Microbiology and Immunology (K.H. Moon, D.H. Kim, M.H. Lee, A. Moon, Y.M. Han, J.H. Lee, K.J. Kim, N.J. Ha, C.Y. Kang, S.H. Kim, E.C. Choi, M.J. Lim, D.K. Rhee, S.R. Pyo, D.H. Nam, J.Y. Lim, J. Jhang, K.M. Lee, B.Y. Kang, J.C. Yoo, K.W. Hwang, H.J. Kim, D.I. Lee, K.S. Chung, S.K. Song, and J.K. Lee) Published by Shinil Publishing Co., Seoul, Korea (2005) 11. "Biopharmaceuticals" (Korean) (ISBN 978-89-5702-181-1) by H.J. Kim and D.H. Nam Published by Shinil Books Publishing Co., Seoul, Korea (2008) 12. “Drug Therapy” 2nd Ed. (Korean) (ISBN 978-89-5702-204-7) by Editorial Board of Clinical Pharmacy (M.H. Kang, W.G. Kang, M.K. Kwak, H.S. Kwak, K.I. Kwon, K.I. Kim, N.D. Kim, S.K. Kim, I.H. Kim, E.Y. Kim, H.A. Kim, J.A. Kim, D.H. Nam, K.J. Park, J.M. Park, J.S. Bang, S.J. Bae, S.H. Baek, E.S. Shin, W.K. Shin, H.T. Shin, S.S. Sim, J.M. Oh, S.H. Wee, B.K. Yoo, H.S. Ryu, S.M. Yoon, M.K. Lee, B.K. Lee, S.Y. Lee, S.H. Lee, S.S. Lee, Y.S. Lee, E.K. Lee, E.S. Lee, E.K. Lee, J.Y. Lee, J.S. Lee, S.S. Lim, K.H. Jeong, H.K. Cho, E.H. Jee, J.S. Choi, J. Bainbridge) Published by Shinil Books Publishing Co., Seoul, Korea (2009) 13. " Pharmaceutical Microbiology" (Korean) (ISBN 978-89-6154-092-6) by Editorial Board of Pharmaceutical Microbiology and Immunology (B.Y. Kang, J.S. Kang, C.Y. Kang, H.J. Koh, J.H. Kwak, K.J. Kim, D.H. Kim, H.J. Kim, D.H. Nam, H.Y. Mheen, S.K. Song, H.S. Shin, J.C. Yoo, K.M. Lee, D.I. Lee, D.K. Rhee, M.H. Lee, B.R. Lee, J.K. Lee, J.Y. Lee, J.H. Lee, M.J. Lim, J.Y. Lim, J. Jhang, S.R. Pyo, N.J. Ha, Y.M. Han, and K.W. Hwang) Published by Life Science Publishing Co., Seoul, Korea (2011) 14. "Biopharmaceuticals" 2nd Ed. (Korean) (ISBN 978-89-5702-260-3) by H.J. Kim and D.H. Nam Published by Shinil Books Publishing Co., Seoul, Korea (2011) General Books 1. “20-Year History of Korean Society for Biotechnology and Bioengineering(1985-2005)” by B.K. Huh, E.S. Kim, I.H. Kim, D.H. Park, Y.J. Yoo, Y.W. Ryu, D.H. Nam, E.K. Lee, J.H. Seo, S.B. Lee, C.S. Shin, C.H. Kim, T.H. Park, and Y.K. Chang Published by Korea Society of Bioengineering and Biotechnology, Seoul, Korea (2005) 2. “50-Year History of College of Pharmacy, Yeungnam University” by S.R. Chung, J.Y. Ryoo, S.H. Yang, M.H. Jeong, J.S. Choi, Y.D. Jhang, H.S. Baek, H.W. Chang, D.H. Nam, J.K. Sohn, S.H. Lee, Y.J. Choo, B.H. Choi, E.J. Choi, and W.J. Kim Published by Alumni Society of College of Pharmacy, Yeungnam University, Daegu, Korea (2005) Technical Presentation : (Since 2000) 1. I. H. Kim, D. H. Nam, and D. D. Y. Ryu Reaction mechanism of cephalexin synthesizing enzyme 47th Ann. Meeting of Korean Chem. Soc., Seoul, Korea (Apr., 1981) 2. H. S. Sohn, D. H. Nam, and D. D. Y. Ryu Enzymatic synthesis of cephaloglycin 49th Ann. Meeting of Korean Chem. Soc., Seoul, Korea (Apr., 1982) 3. D. H. Nam and D. D. Y. Ryu Differential analysis of amikacin and butirosin 31st Ann. Meeting of Pharm. Soc. of Korea, Kwangju, Korea (Oct., 1982) 4. D. D. Y. Ryu and D. H. Nam Enzymatic synthesis of semisynthetic β-lactam antibiotics Ann. Meeting of Japanese Soc. of Enzyme Eng., Osaka, Japan (Nov.,1982) 5. D. H. Nam and D. D. Y. Ryu Enzymatic synthesis of phenoxymethylpenicillin using α-acylamino- β-lactam acylhydrolase from Erwinia aroideae 7th Int. Conference on Enzyme Eng., White Heaven, PA, U.S.A. (Sep., 1983) 6. D. H. Nam, J. H. Kim, and D. D. Y. Ryu Kinetic analysis of cephalexin synthesizing system using Xanthomonas citri enzyme 22nd Ann. Meeting of Korean Soc. for Appl. Microbiol., Seoul, Korea (Oct., 1983) 7. D. H. Nam and D. D. Y. Ryu Relationship between butirosin biosynthesis and sporulation in Bacillus circulans 32nd Ann. Meeting of Pharm. Soc. of Korea, Seoul, Korea (Oct., 1983) 8. H. S. Pai, D. H. Nam, T. H. Chung, M. H. Han, and Y. H. Park A study on the production of new β-lactam antibiotics. I. Thienamycin fermentation using a mutant strain of Streptomyces cattleya 23rd Ann. Meeting of Korean Soc. for Appl. Microbiol., Daejeon, Korea (Apr., 1984) 9. D. D. Y. Ryu and D. H. Nam Reaction kinetics and mechanisms of α-acylamino- β-lactam acylhydrolase in enzymatic synthesis of semisynthetic β-lactam antibiotics 1984 Amer. Chem. Soc., Ann. Meeting, Pensylvania, PA, U.S.A. (Aug., 1984) 10. N. Y. Hur, D. H. Nam, J. H. Kim, J. H. Yu, and D. H. Oh Purification and characterization of ampicillin acylase from Pseudomonas melanogenum The 24th Ann. Meeting of Korea Soc. for Appl. Microbiol., Seoul, Korea (Oct., 1984) 11. Y. W. Ryu, D. D. Y. Ryu and D. H. Nam Preparation and characterization of semisynthetic β-lactam antibiotics synthesizing enzyme from Acetobacter turbidans The 87th Ann. Meeting of Amer. Soc. for Microbiol., Atlanta, GA, U.S.A. (Mar., 1987) 12. D. H. Nam Molecular cloning of antibiotic-producing microorganisms Symp.: Appl. of Biotechnol. for Resource Development, Taegu, Korea (Sep., 1987) 13. K. T. Min, M. H. Kim, D. H. Nam, and D.-S. Lee Oligonucleotide-directed mutagenesis of EcoRI The 14th Int. Congress of Biochem., Prague, Czechoslovakia (Jul., 1988) 14. D. H. Nam, J. H. Koh, M. H. Kim, and D.-S. Lee Construction, cloning, and expression of the gene for (B-30-homoserine) human insulin analog Ann. Meeting of Biochem. Soc. of Rep. of Korea, Seoul, Korea (Nov.,1988) 15. B. C. Park, H. S. Lim, J. H. Ko, S. H. Ko, K. J. Yoo, M. H. Kim, D. H. Nam, S. T. Kwon, and D. S. Lee Production of insulin by genetic engineering Spring Conv. of the Pharm. Soc. of Korea, Seoul, Korea (Apr., 1990) 16. D. H. Nam, D. D. Y. Ryu, D. Ogrydziak, and F. Farahnak Cloning and characterization of the β-galactosidase gene from Kluyveromyces fragilis Asia-Pacific Biochem. Eng. Conf. 1990, Kyoungju, Korea (Apr., 1990) 17. J. W. Roh, J. H. Bang, and D. H. Nam Nutritional requirements for the production of cephabacins by Lysobacter lactamgenus 36th Ann. Meeting of Korean Soc. for Appl. Microbiol., Seoul, Korea (Oct., 1990) 18. J. W. Roh and D. H. Nam Medium optimization for the production of cephabacins by Lysobacter lactamgenus Ann. Meeting of Pharm. Soc. of Korea, Seoul, Korea (Apr. 1991) 19. D. H. Nam, S. Y. Lee, J. H. Ko, and D.-S. Lee Production of insulin analogue by genetic manipulation Int. Congress of New Drug Development, Seoul, Korea (Aug. 1991) 20. M. K. Hong and D. H. Nam Cloning of the biosynthetic gene for cephamycin C from Streptomyces clavuligerus Int. Congress of New Drug Development, Seoul, Korea (Aug. 1991) 21. D.H. Nam Biosynthesis of β-Lactam Antibiotics Symposium of Division of Microbiology, Pharm. Soc. of Korea, Seoul, Korea (Oct. 1991) 22. C. H. Lee, S. A. Yang, J. W. Roh, S. Y. Lee, and D. H. Nam Ethanol fermentation in lactose medium using a fusant strain of Saccharomyces cerevisiae and Kluyveromyces fragilis 38th Ann. Meeting of Korean Soc. for Appl. Microbiol., Seoul, Korea (Oct., 1991) 23. C. H. Lee, D. H. Nam, and K. Huh Identification of an active monomeric form of bovine milk xanthine oxidase Ann. Meeting of Pharm. Soc. of Korea, Seoul, Korea (Apr. 1992) 24. J.W. Roh and D.H. Nam Cephalosporin biosynthesis by cell-free extracts of Lysobacter lactamgenus The 39th Ann. Meeting of Korean Soc. for Appl. Microbiol., Daejeon, Korea (Apr., 1992) 25. D.H. Nam Biosynthetic Genes for β-Lactam Antibiotics Yeungnam Regional Symposium of Korean Soc. for Appl. Microbiol., Kyongju, Korea (Jun., 1992) 26. J. W. Roh, J. H. Bang, and D. H. Nam Nutritional requirement for the production of cephabacins by Lysobacter lactamgenus 9th Internat. Biotechnol. Symposium, Crystal City, VA, U.S.A. (Aug., 1992) 27. C. H. Lee, D. H. Nam, and K. Huh Cloning of xanthine oxidase gene from mouse cDNA library Ann. Meeting of Korean Biochem. Soc., Seoul, Korea (Oct. 1992) 28. J. H. Bang, D. O. Kang, J. S. Ahn and D. H. Nam Subcloning and expression of Kluyveromyces fragilis -galactosidase gene in Saccharmyces cerevisiae The 40th Ann. Meeting of Korean Soc. of Appl. Microbiol., Taegu, Korea (Oct. 1992) 29. S. Y. Lee and D. H. Nam Production and purification of LacZ-fused single chain insulin analogue The 41st Ann. Meeting of Pharm. Soc. of Korea, Daejeon, Korea (Oct. 1992) 30. D. H. Nam Fermentation and biosynthesis of cephabacins by Lysobacter lactamgenus Ann. Meeting of Pharm. Soc. of Korea, Kyongsan, Korea (Apr. 1993) 31. S. A. Yang and D. H. Nam Production and characterization of α-amino acid ester hydrolase from Xanthomonas citri Ann. Meeting of Pharm. Soc. of Korea, Kyongsan, Korea (Apr. 1993) 32. S. Y. Lee, D. H. Nam, and T. Chung The role of AP-1 binding sites of human foamy virus LTR in the transcriptional regulation of viral expression Spring Conf. on Biochem. & Mol. Biol., Seoul, Korea (May 1993) 33. S. Y. Lee, M. H. Choi, J. H. Ko, and D. H. Nam Fermentation and purification of lacZ-fused single chain insulin precursor for (B30homoserine) human insulin Ann. Symp. of Bioprocess Eng. Center, Daejeon, Korea (Sep. 1993) 34. D. H. Nam, J. H. Ko, and S. Y. Lee Cloning of the gene for a novel insulin analog, (B30-homoserine) human insulin, and its production in Escherichia coli Merging Pharmaceutics with Biopharmacy, Seoul, Korea (Dec. 1993) 35. M. H. Choi, M. K. Hong, and D. H. Nam Expression of Streptomyces clavuligerus isopenicillin N synthetase gene in Escherichia coli 14th Ann. Meeting of Korean Inst. of Biotechnol. and Bioeng. Daejeon, Korea (Apr.1994) 36. D. H. Nam Development of new anti-diabetic drug by genetic engineering technique Ann. Meeting of Korean Soc. of Appl. Pharmacol., Seoul, Korea (Apr. 1994) 37. C. H. Lee, S. I. Lee, D. H. Nam, and K. Huh Cloning of xanthine oxidase gene from mouse liver cDNA library Ann. Meeting of Korean Soc. of Appl. Pharmacol., Seoul, Korea (Apr. 1994) 38. D. H. Nam, J. H. Ko, and S. Y. Lee Cloning of the gene for a novel insulin analog, (B30-homoserine) human insulin, and its production in Escherichia coli 7th Intern. Symp. on the Genetics of Ind. Microorg., Montreal, Canada (Jun. 1994) 39. J. M. Kim, K. Huh, and D. H. Nam Oxygen toxicity of superoxide dismutase-deficient Sacchromyces cervisiae by paraquat Ann. Meeting of Korean Inst. of Biotechnol. and Bioeng. Daejeon, Korea (Apr. 1995) 40. S. W. Kim and D. H. Nam Expression and purification of B30-homoserine human insulin analogue in Escherichia coli Ann. Meeting of Korean Biochem. Soc., Seoul, Korea (May. 1995) 41. J. K. Lee, J. M. Kim, D. H. Nam, and K. Huh Oxygen toxicity of superoxide dismutase-deficient Sacchromyces cervisiae induced by copper ion Ann. Meeting of Korean Inst. of Biotechnol. and Bioeng. Chonan, Korea (Oct. 1995) 42. D. H. Nam, C. H. Lee, and J. S. Yeo RAPD (Random amplified polymorphic DNA) analysis of Hanwoo (Korean cattle) genome 6th Ann. Congr. of Kor. Fed. of the Soc. in Animal Sci., Chonju, Korea (Jun. 1996) 43. J. M. Kim, J. K. Lee, D. H. Nam, and K. Huh Adaptation profile of superoxide dismutase-deficient Sacchromyces cervisiae to oxygen radicals generated by paraquat and copper ion 9th Int. Symp. on Yeasts, Sydney, Australia (Aug. 1996) 44. S. Y. Lee, M. H. Choi, J. H. Ko, and D. H. Nam Preparation of polyclonal antibody against ampicillin acylase of Xanthomonas citri Ann. Symp. of Bioprocess Eng. Center, Daejeon, Korea (Sep. 1996) 45. D. H. Nam, S. M. Lee, and M. J. Kim Ethanol production by superoxide dismutase (SOD)-deficient Saccharomyces cerevisiae under oxidative stresses Ann. Meeting of Korean Inst. of Biotechnol. and Bioeng. Pusan, Korea (Oct. 1996) 46. J. M. Kim, D. H. Nam, S. M. Lee, and M. J. Kim Ethanol production by superoxide dismutase (SOD)-deficient Saccharomyces cerevisiae under oxidative stresses 5th Pacific Rim Biotechnol. Conf. Seoul, Korea (Nov. 1996) 47. M. J. Kim and D. H. Nam Gene cloning of α-amino acid ester hydrolase from Xanthomonas citri Commemorating 30th Anniversary of Korean Biochem. Soc, Seoul, Korea (May, 1997) 48. D. H. Nam, C. H. Lee, J. S. Lee, T. W. Chung, and J. S. Yeo AP-PCR (arbitrarily primed-polymerase chain reaction) pattern of Hanwoo (Korean cattle) genome 7th Ann. Congr. of Kor. Fed. of the Soc. in Animal Sci., Seoul, Korea (Jun. 1997) 49. S. H. Park, Y. S. Ryu, S. W. Kim, J. S. Lee and D. H. Nam Purification of Single Chain Human Insulin Precursor by Affinity Chromatography Ann. Meeting of Korean Inst. of Biotechnol. and Bioeng. Chonju, Korea (Apr. 1998) 50. J. S. Lee and D. H. Nam Fermentation of Recombinant Insulin Analogue in Escherichia coli and Its Purification by Affinity Chromatography The 47th Ann. Meeting of Pharm. Soc. of Korea, Chonju , Korea (Oct. 1998) 51. D. H. Nam Antibiotic Resistance and Public Health 1st Seminar for the Preparation of Future in Korean Cattle Industry, by Easy System Inc., Seoul, Korea (Apr. 1999) 52. D. H. Nam Recent Progress in Biomolecular Engineering ’99 Seminar of Institute of Pharmacy, Chung-Ang University, Seoul, Korea (May 1999) 53. D. H. Nam Biomolecular Engineering and Drug Development ’99 Seminar of Institute of Pharmacy, Chosun University, Kwangju, Korea (Jul. 1999) 54. D. H. Nam, J. W. Kim, T. K. Chang, and J. S. Yeo Development of specific probe for Hanwoo capable of disciminating from foreign cattles 10th Ann. Congr. of Kor. Fed. of the Soc. in Animal Sci., Chuncheon, Korea (Jun. 1999) 55. J. S. Lee and D. H. Nam Design of a novel insulin analogue by recombinant DNA technique 1999 U.S.-Korea Conf. on Sci., Technol., Enterpreneurship and Leadersgip, LA, CA, USA. (Aug. 1999) 56. E. J. Kim, D. H. Nam, Y. J. Jung, S. J. Kang, S. Y. Chang, and K. W. Ha Molecular discrimination of antlers from Cervidae and Rangifer species 48th Ann. Conv. of Pharm. Soc. of Korea, Seoul, Korea (Oct. 1999) 57. S. H. Park, C.W Choi, and D. H. Nam One-step purification of His-tagged B30-homoserine insulin precursor using nickel-affinity chromatography system ‘99 Ann. Meeting of Korean Soc. for Appl. Microbiol., Taegu, Korea (Oct. 1999) 58. D. H. Nam, Y. S. Sohn, and Dewey D. Y. Ryu Two putative transporter genes in cephabacin biosynthetic gene cluster of Lysobacter lactamgenes ‘99 Ann. Meeting of Korean Soc. for Appl. Microbiol., Taegu, Korea (Oct. 1999) 59. D. H. Nam Engineered biosynthesis of hybrid antibiotics 6th Symp. of Inst. for Drug Develop., Yeungnam Univ., Taegu, Korea (Nov. 1999) 60. K. W. Ha, S. Y. Chang, S. J. Kang, Y. J. Jung, J. H. Shin, J. H. Kim, E. J. Kim, D. H. Nam, and H. J. Kim Quality evaluation of animal drugs (I) quality control and identification of Cervi Parvum Cornu by molecular biological method 30th Ann. Meeting of Korean Soc. of Pharmacognosy, Seoul, Korea (Dec. 1999) 61. K. W. Ha, S. Y. Chang, S. J. Kang, D. H. Kim, Y. J. Jung, J. P. Lee, J. Y. Park, C. H. Cho, H. J. Kim, and D. H. Nam Quality evaluation of animal drugs (II) quality control and analysis of Cervi Parvum Cornu by near infrared (NIR) spectrum 30th Ann. Meeting of Korean Soc. of Pharmacognosy, Seoul, Korea (Dec. 1999) 62. D. H. Nam Engineered biosynthesis of hybrid antibiotics Taegu-Kyongbuk Regional Meeting of Korean Soc. for Appl. Microbiol., Taegu, Korea (Dec. 1999) 63. D. H. Won, S. Y. Chang, Y .J. Jung, S. J. Kang, R. S. Seong, J. P. Lee, J. H. Shin, J. H. Kim, C. H. Cho, H. J. Kim, E. J. Kim, and D. H. Nam Molecular discrimination of antlers from Cervidae and Rangifer species. 41st Ann. Meeting of Amer. Soc. of Pharmacognosy, Seattle, WA, U.S.A. (Jul. 2000) 64. E. J. Kim, Y. J. Jung, S. J. Kang, S. Y. Chang, K. S. Kim, K. Huh, and D. H. Nam Discrimination of Cervidae antlers from Rangifer antlers based on the sequences of mitochondrial cytochrome b gene 49th Ann. Conv. of Pharm. Soc. of Korea, Seoul, Korea (Oct. 2000) 65. D. C. Cipolla, D. H. Nam, Y. W. Ryu, and D. D. Y. Ryu pH-controlled synthesis of cephalexin by a purified Acetobacter turbidans ampicillin acylase Ann. Meeting of Korean Soc. for Appl. Microbiol.-2000, Chonju, Korea (Oct. 2000) 66. S. H. Park, J. W. Cho, and D. H. Nam Purification of single chain human insulin precursor using various fusion proteins 2000 Ann. Meeting of Korean Inst. of Biotechnol. and Bioeng. Chonan, Korea (Nov. 2000) 67. D. H. Nam Manipulation of polyketide synthase and polypeptide synthetase for the generation of hybrid antibiotics Taegu-Kyongbuk Regional Meeting of Korean Inst. of Biotechnol. and Bioeng., Taegu, Korea (Jun. 2001) 68. H. J. Kim, T. J. Oh, J. K. Sohng, K. K. Ryu, and D. H. Nam Biosynthesis of GERI-155 Ann. Meeting of Korean Soc. for Appl. Microbiol.-2001, Chonan, Korea (Jun. 2001) 69. S. K. Lim, H. S. Chang, Y. J. Jung, J. A. Kim, K. Huh, and D. H. Nam Genetic diversity of mitochondrial DNA in antlers of Cervidae and related species. 50th Int. Conv. of Pharm. Soc. of Korea, Seoul, Korea (Oct. 2001) 70. S. K. Lim, J. K. Sohng, J. C. Yoo, W. G. Kim, I. D. Yoo, and D. H. Nam Cloning of type I polyketide synthase gene cluster for the biosynthesis of GERI-155 2001 Biochem. Mol. Biol. (Ann. Meeting of Biochem. Soc of ROK), Seoul, Korea (Oct. 2001) 71. S. K. Lim, J. W. Choi, and D. H. Nam Isolation of Streptomyces sp. YU100 producing extracellular phospholipase D 2001 Int. Meeting of the Fed. of Kor. Microbiol. Soc., Seoul, Korea (Oct. 2001) 72. H. S. Chang, S. K. Lim, E. J. Kim, D. H. Nam, and K. Huh Allergenicity test of genetically modified soybean extract in rat 2002 Spring Conv. of Pharm. Soc. of Korea, Seoul, Korea (Apr. 2002) 73. H. J. Kim, J. K. Sohng, S. K. Lim, D. H. Nam, and J. C. Yoo The cloning and analysis of GERI-155 biosynthetic genes from Streptomyces sp. GERI-155 9th Intern. Symp. on the Genetics of Ind. Microorg., Gyongju, Korea (Jul. 2002) 74. J. C. Yoo, D. H. Nam, I. D. Yoo, J. K. Sohng, J. M. Han, and J. H. Kim Heterologous expression, purification, and biochemical characterization of dTDP-glucose 4,6dehydratase gene cloned from Streptomyces sp. GERI-155 9th Intern. Symp. on the Genetics of Ind. Microorg., Gyongju, Korea (Jul. 2002) 75. J. C. Yoo, J. M. Han, J. H. Kim, D. H. Nam, J. K. Sohng, and C. N. Seong Optimization of culture conditions for the production of protease by Streptomyces tendae JC412 isolated from Korean soil 9th Intern. Symp. on the Genetics of Ind. Microorg., Gyongju, Korea (Jul. 2002) 76. H. S. Chang, N. H. Kim, S. K. Lim, T. C. Jeong, K. Huh and D. H. Nam Gene expression and purification of 5-enolpyruvylshikimate synthase of genetically modified soybean for the evaluation of allergenic potential. 9th Intern. Symp. on the Genetics of Ind. Microorg., Gyongju, Korea (Jul. 2002) 77. S. K. Lim, J. W. Choi, M. H. Chung, K. M. Seok, E. T. Lee, S. D. Kim, Y. H. Khang and D. H. Nam Production and characterization of extracellular phospholipase D from Streptomyces sp. YU100. 9th Intern. Symp. on the Genetics of Ind. Microorg., Gyongju, Korea (Jul. 2002) 78. S. K. Lim, J. K. Sohng, J. C. Yoo, W. G. Kim, I. D. Yoo, and D. H. Nam Cloning and sequencing of type I polyketide synthase gene cluster homolog in Streptomyces sp. GERI-155, a producer of macrolide antibiotic GERI-155. 9th Intern. Symp. on the Genetics of Ind. Microorg., Gyongju, Korea (Jul. 2002) 79. D. H. Nam, C. H. Choi, K. H. Kee, S. W. Kim, J. M. Han, J. H. Kim, H. J. Lee, and J. C. Yoo Isolation, production, purification and biochemical properties of thermostable protease produced by Actinomycetes CS0707 isolated from Korean soil. 51st Int. Conv. of Pharm. Soc. of Korea, Osong, Korea (Oct. 2002) 80. C. N. Seong, D. H. Nam, S. J. Kim, S. S. Cho, J. M. Han, J. H. Kim, H. J. Lee and J. C. Yoo Biochemical analysis of a high-molecular-weight protease from Streptomyces tendae JC412 51st Int. Conv. of Pharm. Soc. of Korea, Osong, Korea (Oct. 2002) 81. C. N. Seong, O. H. Lee, S. Kim, Y. K. Yang, J. H. Kim, S. H. Kim, D. H. Nam, and J. C. Yoo Two thermostable proteases of Actinomycetes CS0704: isolation, production, purification and characterization. Ann. Meeting of Korean Soc. for Microbiol. and Biotechnol.-2002, Seoul, Korea (Oct. 2002) 82. H. S. Chang, S. K. Lim and D. H. Nam Nonribosomal peptide synthetase modules in cephabacin biosynthetic gene cluster of Lysobacter lactamgenus 8th Intern. Pacific Rim Biotechnol. Conf. Auckland, New Zealand (Nov. 2002) 83. D. H. Nam Antibiotic biosynthesis - from natural to unnatural -. 2003 Sungwoo Symp. of Korea BioPharmaceut. Soc., Hoengseong, Korea (Feb. 2003) 84. J. S. Lee, J. G. Park, J. W. Cho, S. H. Park, and D. H. Nam. Production of human insulin analogue using recombinant Escherichia coli. 2003 Ann. Meeting of Korean Soc. for Biotechnol. and Bioeng. Pusan, Korea (Apr. 2003) 85. J. W. Lee, S. C. Kim, A. Yoo, H. S. Chang, K. H. Lee, J. M. Park, and D. H. Nam. Bioequivalence assessment of domperidone maleate tablets in healthy human volunteers. 2003 Spring Conv. of Pharm. Soc. of Korea, Kyongsan, Korea (Apr. 2003) 86. S. S. Cho, J. M. Han, J. H. Choi, D. H. Nam, J. K. Sohng, C. N. Seong, and J. C. Yoo. Production, purification and characterization of extracellular phospholipase D from thermoalkaliphilic Actinomycetes CS0708. 2003 Int. Meeting of Microbiol. Soc. of Korea, Chunchon, Korea (Apr. 2003) 87. D. H. Nam, H. J. Kim, J. K. Sohng, S. S. Cho, J. H. Kim, J. H. Choi, J. C. Yoo. The cloning and analysis of Sch47554 and Sch47555 biosynthetic genes as angucycline-type antibiotics from Streptomyces SCC-2136. 2003 Int. Meeting of Microbiol. Soc. of Korea, Chunchon, Korea (Apr. 2003) 88. B. P. Jaishy, S. K. Lim, J. K. Sohng, J. C. Yoo, and D. H. Nam. Isolation and analysis of Geri-155 biosynthetic gene cluster from Streptomyces sp. Geri-155. 2003 Int. Meeting of Microbiol. Soc. of Korea, Chunchon, Korea (Apr. 2003) 89. H. S. Chang, M. J. Park, A. Demirev, and D. H. Nam Biosynthetic gene cluster of cephabacin for the combinatorial biosynthesis of -lactam antibiotics 2003 Int. Conv. of Pharm. Soc. of Korea, Seoul, Korea (Oct. 2003) 90. M. J. Park, M. O. Lim, and D. H. Nam Expression and characterization of ATP-binding cassette (ABC) transporter in cephabacin biosynthesis gene cluster of Lysobacter lactamgenus 2003 Int. Conv. of Pharm. Soc. of Korea, Seoul, Korea (Oct. 2003) 91. A. Yoo, S. C. Kim, J. M. Park, K. H. Lee, and D. H. Nam Bioequivalence assessment of Shinpoong “Dompil” tablets containing domperidone maleate in healthy Korean volunteers 2003 Int. Conv. of Pharm. Soc. of Korea, Seoul, Korea (Oct. 2003) 92. A. Demirev, H. S. Chang, and D. H. Nam Purification and biochemical characterization of adenylation domains included in NRPS modules of biosynthetic gene cluster of cephabacins in L. lactamgenus 2003 Int. Meetings of Fed. of Korean Microbiol. Soc., Seoul, Korea (Oct. 2003) 93. J. M. Han, S. S. Cho, J. H. Choi, H. J. Lee, D. H. Nam, J. S. Piao, J. K. Sohng, and J. C. Yoo Expression of glucose-1-phosphate thymydyltransferase gene involved in deoxysugar bioynthesis from Streptomyces sp. GERI-155 and biochemical properties of the expressed protein 2003 Int. Meetings of Fed. of Korean Microbiol. Soc., Seoul, Korea (Oct. 2003) 94. J. O. Yon, S. K. Lim, and D. H. Nam Immobilization of phospholipase D produced by Streptomyces YU100 on macroporous supports 2003 Int. Meetings of Fed. of Korean Microbiol. Soc., Seoul, Korea (Oct. 2003) 95. D. H. Nam Analysis of gene cluster for the biosynthesis of cephem antibotic The 1st Asian Symp. for Pharm. Sci., Kyushu Univ. Fukuoka, Japan (Jan. 2004) 96. A. Demirev, H.. S. Chang, and D. H. Nam Substrate specificities of adenylation domains in nonribosomal peptide synthetase modules of biosynthetic gene cluster for cephabacins in Lysobacter lactamgenus 2004 Intern. Meeting of Microbiol. Soc. of Korea, Chonan, Korea (May 2004) 97. S. S. Cho, J. H. Choi, S. J. Kim, O. H. Lee, D. H. Nam, J. K. Sohng, B. Sthapit, and J. C. Yoo Molecular cloning and identification of deoxysugar biosynthetic genes of aculose and amicetose moieties of Sch 47555 and 47554 from Streptomyces sp. SCC-2136 2004 Intern. Meeting of Microbiol. Soc. of Korea, Chonan, Korea (May 2004) 98. D. H. Nam, B. Jaishy, S. K. Lim, J. K. Sohng, J. C. Yoo, and I. D. Yoo Isolation and characterization of a gene cluster for the polyketide macrolide antibiotic dihydrochalcomycin (GERI-155) in Streptomyces sp. GERI-155 104th General Meeting of Amer. Soc. of Microbiol., New Orleans, LA, USA (May 2004) 99. M. O. Lim, J. S. Lee and D. H. Nam Production of intracellular and extracellular lipstatin from Streptomyces toxytricini NRRL15443 2004 Int. Meetings of Fed. of Korean Microbiol. Soc., Seoul, Korea (Oct. 2004) 100. A. Yoo, B. P. Jaishy and D. H. Nam Cloning of type II polyketide synthase (PKS) gene from Streptomyces toxytricini NRRL15433 2004 Int. Meetings of Fed. of Korean Microbiol. Soc., Seoul, Korea (Oct. 2004) 101. A. Demirev, J. S. Lee and D. H. Nam Substrate specificity of adenylation domains included in non-ribosomal peptide synthetase modules of biosynthetic gene cluster for cephabacins in Lysobacter lactamgenus 2004 Conv. of Pharm. Soc. of Korea, Seoul, Korea (Oct. 2004) 102. B. P. Jaishy, J. K. Sohng, J. C. Yoo, and D. H. Nam Isolation and characterization of a gene cluster for the polyketide macrolide antibiotics dihydrochalcomycin (GERI-155) in Streptomyces sp. GERI-155 2004 Conv. of Pharm. Soc. of Korea, Seoul, Korea (Oct. 2004) 103. A. Demirev and D. H. Nam Nonribosomal peptide synthetase involved in the biosynthesis of cephem antibiotic The 8th China-Japan-Korea Joint Symp. on Enzyme Eng., Hangzhou, China (Oct. 2004) 104. J. S. Lee, H. G. Choi, Y. W. Kim, J. Y. Kim and D. H. Nam Pharmacological effect of Dioscoreae rhizoma extract on gastrointestinal motility 2004 Ann. Meeting of Kor. Soc. of Appl. Pharmacol., Seoul, Korea (Nov. 2004) 105. D. H. Nam Instruction of antimicrobial drug administration 2004 Ann. Education Program of Daegu Pharmacist Association., Daegu, Korea (Nov. 2004) 106. D. H. Nam Combinatorial biosynthesis of antibiotics Kor. Intellectural Property Office, Daejon, Korea (Dec. 2004) 107. K. Y. Cho, J. S. Lee and D. H. Nam Molecular identification of medicinal mushrooms based on 25S rDNA sequences 2005 Conv. of Pharm. Soc. of Korea, Seoul, Korea (Apr. 2005) 108. A. V. Demirev and D. H. Nam Substrate specificity of adenylation domains included in NRPS modules of cephabacin biosynthetic gene cluster 2005 Intern. Meeting of Microbiol. Soc. of Korea, Hoengseong, Korea (May 2005) 109. B. P. Jaishy, S. K. Lim, J. K. Sohng, J. C. Yoo, and D. H. Nam Complete genome structure for the biosynthesis of macrolide antibiotic dihydrochalcomycin (GERI-155) in Streptomyces sp. GERI-155 2005 Intern. Meeting of Microbiol. Soc. of Korea, Hoengseong, Korea (May 2005) 110. B. P. Jaishy, S. K. Lim, J. K. Sohng and D. H. Nam Confirmation of the biosynthetic gene cluster for macrolide antibiotic dihydrochalcomycin (GERI-155) by gene distruption in Streptomyces sp. 2005 Intern. Meeting of Microbiol. Soc. of Korea, Hoengseong, Korea (May 2005) 111. I. Yoon, M. Lim, J. S. Lee, S. D. Kim and D. H. Nam Fermentative study of lipstatin by Streptomyces toxytricini Asia-Pacific Biochem. Eng. Conf. 2005, Jeju, Korea (May 2005) 112. B. P. Jaishy, J. K. Sohng, J. C. Yoo, and D. H. Nam Cloning of a gene cluster for the biosynthesis of macrolide antibiotics dihydrochalcomycin (GERI-155) from Streptomyces sp. GERI-155 Joint Meeting of Intern. Union of Micorbiol. Soc. (IUMS) 2005, San Francisco, CA, USA (Jul. 2005) 113. B. P. Jaishy, S. K. Lim, J. K. Sohng, J. C. Yoo, I. D. Yoo, and D. H. Nam Complete biosynthetic gene structure for macrolide antibiotic, dihydrochalcomycin, in Streptomyces sp. GERI-155 Mongolia-Korea Joint Symp. on Microbiol. 2005, Ulaanbaartar, Mongolia (Aug. 2005) 114. A. Demirev, J. S. Lee, and D. H. Nam Identification of accA1 and accB1 Genes - the two subunits of acyl-CoA carboxyltransferase in Streptomyces toxytricini 2005 Int. Meetings of Fed. of Korean Microbiol. Soc., Seoul, Korea (Oct. 2005) 115. S. K. Hong, Y. S. Hong, E. K. Oh, Y. W. Kim, C. S. Shin, E. K. Kim, B. K. Kim, and D. H. Nam Recent trend analysis and policy development for performance chemical research 2005 Ann. Meeting of Korean Soc. for Biotechnol. and Bioeng. Jinju, Korea (Oct. 2005) 116. J. S. Lee, S. D. Kim, and D. H. Nam Molecular cloning and heterologous expression of phospholipase D from Streptomyces sp. YU100 2005 Ann. Meeting of Korean Soc. for Biotechnol. and Bioeng. Jinju, Korea (Oct. 2005) 117.Y. H. Shim, D. H. Kim, M. H. Oh, H. Y. Jung, C. H. Cho, H. K. Lim, J. H. Baek, C. D. Park, H. Y. Choi, D. H. Nam, and J. H. Cho Identification of Hoelen species in the herbal medicinal products using molecular biological analysis method 2005 Conv. of Pharm. Soc. of Korea, Seoul, Korea (Nov. 2005) 118. D. H. Nam, K. O. Shin, S. D. Kim, J. Y. Kim, and S. K. Lim Lactic acid fermentation of Dioscorea rhizome 2005 Conv. of Pharm. Soc. of Korea, Seoul, Korea (Nov. 2005) 119. B. P. Jaishy and D. H. Nam Cloning and characterization of a gene cluster involved in the biosynthesis of polyketide antibiotic dihydrochalcomycin in Streptomyces sp. KCTC 0041BP 2006 Intern. Meeting of Microbiol. Soc. of Korea, Daegu, Korea (May 2006) 120. W. Yin, B. P. Jaishy and D. H. Nam Gene disruption of putative O-methyltransferase genes involved in dihydrochalcomycin biosynthesis of Streptomyces sp. KCTC BP0041 for the identification of their biological functions 2006 Intern. Meeting of Microbiol. Soc. of Korea, Daegu, Korea (May 2006) 121. J. W. Ha, H. J. Lee, S. M. Kim, J. K. Sohng, D. H. Nam, N. S. Park, and J. C. Yoo Construction of polyether antibiotics-carrier protein conjugates 2006 Intern. Meeting of Microbiol. Soc. of Korea, Daegu, Korea (May 2006) 122. A. Demirev, J. S. Lee, and D. H. Nam Identification of accA1 and accD1, the genes encoding two subunits of Streptomyces toxytricini acyl-CoA carboxyltransferase 2006 Spring KSBB Ann. Meeting and Intern. Symp., Cheongju, Korea (May 2006) 123. T. T. T. Thuy, K. Liou, H. C. Lee, T. J. Oh, D. H. Nam, and J. K. Sohng Targeted inactivation and characterization of two glycosyltransferase genes in the GERI-155 biosynthesis gene cluster from Streptomyces sp. KCTC BP0041 2006 Ann. Meeting and Intern. Symp.on Syst. Innov. for Microb. Diversity, Busan, Korea (Jun. 2006) 124. J. K. Sohng, T. T. T. Thuy, K. Liou, T. J. Oh, D. H. Nam, and J. C. Yoo Biosynthesis of dTDP-6-deoxy--D-allose, biochemical characterization of dTDP-4-keto-6deoxyglucose reductase (GerK1) from Streptomyces sp. KCTC BP0041 10th Intern. Symp. on the Genetics of Ind. Microorg., Prague, Czech (Jun. 2006) 125. A. V. Demirev, J. S. Lee, and D. H. Nam Identification of accA1 and accD1 - the genes encoding two subunits of Streptomyces toxytricini acyl-CoA carboxyltransferase 10th Intern. Symp. on the Genetics of Ind. Microorg., Prague, Czech (Jun. 2006) 126. W. Yin, B. P. Jaishy, B. G. Kim and D. H. Nam Gene disruption of putative O-methyltransferase genes involved in dihydrochalcomycin biosynthesis of Streptomyces sp. KCTC BP0041 for the identification of their biological Functions 10th Intern. Symp. on the Genetics of Ind. Microorg., Prague, Czech (Jun. 2006) 127. B. P. Jaishy, S. K. Lim, J. K. Sohng, J. C. Yoo, I. D. Yoo, and D. H. Nam Biosynthetic gene organization for macrolide antibiotic dihydrochalcomycin in Streptomyces sp. GERI-155 10th Intern. Symp. on the Genetics of Ind. Microorg., Prague, Czech (Jun. 2006) 128. B. P. Jaishy, S. K. Lim, J. K. Sohng and D. H. Nam Distruption of polyketide synthase gene for the confirmation of the biosynthesis of macrolide antibiotic dihydrochalcomycin (GERI-155) in Streptomyces sp. KCTC0041BP 10th Intern. Symp. on the Genetics of Ind. Microorg., Prague, Czech (Jun. 2006) 129. J. W. Ha, J. R. Shimkada, T. B. Vu, N. S. Park, J. K. Sohng, D. H. Nam, and J. C. Yoo Identification and expression of phospholipase D from Streptomycesladiologenes CS.684 2006 Int. Meetings of Fed. of Korean Microbiol. Soc., Seoul, Korea (Oct. 2006) 130. A. Demirev, J. S. Lee, and D. H. Nam Acyl-CoA carboxylase of Streptomyces toxytricini 2006 Int. Meetings of Fed. of Korean Microbiol. Soc., Seoul, Korea (Oct. 2006) 131. A. Demirev, J. S. Lee, and D. H. Nam Acyl-CoA carboxylase of Streptomyces toxytricini The 9th Japan-China- Korea Joint Symp. on Enzyme Eng., Otsu, Japan (Nov. 2006) 132. B.G. Kim, J.S. Lee, Y.S. Yu, J.R. Jeon, J.Y. Kim, and D.H. Nam Effect of ethanol extract from dried Chinese yam (Dioscorea batatas) flour on gastro-intestinal function in rat model The 3rd China-Korea-Japan Joint Symp. on Pharmacog., Hangzhou, China (Nov. 2006) 133. J.S. Lee, B.G. Kim, and D.H. Nam Cloning and gene expression of Streptomyces sp. YU100 phospholipase D in Escherichia coli The 1st Indonesia-Korea Biotechnol. Symp., Jakarta, Indonesia (Jan. 2007) 134. D.H. Nam Gene cloning and characterization involved in the biosynthesis of dihydrochalcomycin in Streptomyces sp. KCTC 0041BP The 35th Korean Soc. of Ind. and Eng. Chem. Meeting, Daegu, Korea (May 2007) 135. D.H. Nam, M.G. Vladimirova, A.V. Demirev, and J.-S. Lee Characterization of polyketide synthase modules involved in the late step of cephabacin biosynthesis from Lysobacter lactamgenus. The 107th General Meeting of Amer. Soc. of Microbiol., Toronto, ON, Canada (May 2007) 136. M.G. Vladimirova, A.V. Demirev, J.S. Lee, and D.H. Nam Characterization of polyketide synthase modules in biosynthetic gene cluster for cephabacin of Lysobacter lactamgenus. The 19th FAOBMB(Fed. of Asian and Oceanian Biochem. And Mol. Biol.) Seoul Conf., Seoul, Korea (May 2007) 137. A.V. Demirev, J.S. Lee and D.H. Nam Cloning and identification of genes encoding two subunits of acyl-CoA carboxylase (AccA1 and AccD1) from Streptomyces toxytricini 2007 Intern. Symp. & Ann. Meeting of Kor. Soc. for Microbiol. & Biotechnol., Seoul, Korea (June 2006) 138. B.R. Sedai, W. Yin and D.H. Nam Characterization of O-methyltransferase genes in dihydrochalcomycin biosynthesis gene cluster of Streptomyces sp. KCTC BP0041. 2007 Intern. Symp. & Ann. Meeting of Kor. Soc. for Microbiol. & Biotechnol., Seoul, Korea (June 2007) 139. D.H. Nam and J.S. Lee Identification of the genes in 11kb chromosomal DNA from lipstatin producer Streptomyces toxytricini: of accA1 and accD1 - the genes encoding two subunits of acyl CoA carboxylase The 11th China-Korea Regional Symp. on Biotechnol., Dalian, China (Aug. 2007) 140. J.S. lee. B.G. Kim, and D.H. Nam PCR-targeted gene replacement of polyketide synthase involved in the biosynthesis of polyketide antibiotic dihydrochalcomycin (Geri-155) in Streptomyces sp. KCTC 0041BP. 2007 Intern. Meetings of Fed. of Korean Microbiol. Soc., Seoul, Korea (Oct. 2007) 141. B.R. Sedai, J.S. Lee and D.H. Nam Cloning of gene cluster involved in the biosynthesis of polyether antibiotic laidlomycin from Streptomyces sp. CS684 2007 Intern. Meetings of Fed. of Korean Microbiol. Soc., Seoul, Korea (Oct. 2007) 142. B.G. Kim, J.C. Park, J.Y. Kim, Y.J. Lee, S.H. Lee and D.H. Nam Protective effect of Oenanthe javanica Extract on acetaminophen-induced hepatotoxicity in rats 2007 Conv. of Pharm. Soc. of Korea, Seoul, Korea (Nov. 2007) 143. J.S. Lee, J.Y. Kim, K.H. Kim, Y.J. Lee, S.H. Lee, J.C. Park, and D.H. Nam Accelerative ethanol metabolism by administration of Oenanthe javanica extract in ethanoltreated animals 2007 Conv. of Pharm. Soc. of Korea, Seoul, Korea (Nov. 2007) 144. J.S. Lee, B.G. Kim, and D.H. Nam Generation of 14-membered macrolide antibiotic by PCR-targeted gene disruption of polyketide synthase involved in the biosynthesis of 16-membered dihydrochalcomycin Vietnam Korea Joint Symp. on Biotechnol. Bioeng., Ho Chi Minh City, Vietnam (Jan. 2008) 145. A. V. Demirev, J. S. Lee, and D. H. Nam Post-translational modification of AccA – the alpha subunit of ACC by Streptomyces toxytricini biotin apo-protein ligase The 48th MSK Ann. Meeting and 2008 Intern. Symp. on Microbiol. Daejon, Korea (May 2008) 146. J. S. Lee, B. G. Kim and D. H. Nam In-frame gene deletion of polyketide synthase modules for the biosynthesis of dihydrochalcomycin in Streptomyces sp. KCTC 0041BP by PCR-targeting The 48th MSK Ann. Meeting and 2008 Intern. Symp. on Microbiol. Daejon, Korea (May 2008) 147. J. S. Lee, B. G. Kim and D. H. Nam PCR-targeted disruption of polyketide synthase modules involved in the biosynthesis of dihydrochalcomycin in Streptomyces sp. KCTC 0041BP. Meetings of 3 Divisions of Intern. Union of Micorbiol. Soc. (IUMS) 2008, Istanbul, Turkey (Aug. 2008) 148. A. V. Demirev, J. S. Lee, and D. H. Nam Cloning and biochemical characterization of biotin apo-protein ligase (BPL) from Streptomyces toxytricini Meetings of 3 Divisions of Intern. Union of Micorbiol. Soc. (IUMS) 2008, Istanbul, Turkey (Aug. 2008) 149. B. R. Sedai, J. S. Lee, J. C. Yoo, C. N. Seong, and D. H. Nam Cloning a part of gene cluster for the biosynthesis of a polyether antibiotic, laidlomycin, from Streptomyces sp. KCTC 10631BP Meetings of 3 Divisions of Intern. Union of Micorbiol. Soc. (IUMS) 2008, Istanbul, Turkey (Aug. 2008) 150. A. V. Demirev, J. S. Lee, and D. H. Nam Post-translational modification of AccA – the alpha subunit of acyl-CoA carboxylase by Streptomyces toxytricini biotin apo-protein ligase The 10th Korea-China Japan Joint Symp. on Enzyme Eng., Busan, Korea (Nov. 2008) 151. A. V. Demirev, J. S. Lee, and D. H. Nam Characterization of biotin apo-protein ligase from Streptomyces toxytricini 2009 KSBB Spring Meeting and Intern. Symp., Pohang, Korea (Apr. 2009) 152. A. V. Demirev, J. S. Lee, and D. H. Nam Identification and characterization of acetyl-CoA carboxylase gene cluster in Streptomyces toxytricini MSK,s 50th Anniversary Intern. Symp. on Microbiol. 2009, Jeju, Korea (May, 2009) 153. A. V. Demirev, J. S. Lee, M. K. Na, and D. H. Nam Confirmation of acetyl-CoA carboxylase from Streptomyces toxytricini involved in the lipstatin biosynthesis 2009 Intern. Symp. & Ann. Meeting of KMB, Daejeon, Korea (Jun., 2009) 154. A. V. Demirev, A. Khanal, D.-H. Nam Characterization of acyl-CoA carboxylase complex for the secondary metabolism in Streptomyces toxytricini 2009 Intern. Meetings of Fed. of Korean Microbiol. Soc., Seoul, Korea (Oct. 2009) 155. J. Y. Hwang, N. P. K. Hanh, and D. H. Nam The Organization of Gene Cluster in the Length of 55kb for the Biosynthesis of a Polyether Antibiotic, Laidlomycin, from Streptomyces sp. KCTC 10631BP 2010 Intern. Symp. on Microbiol. Soc. of Korea. Uljin, Korea (May 2010) 156. A. Khanal and D.-H. Nam Biochemical Properties of Acyl-CoA Carboxylase Complex for the Secondary Metabolism in Streptomyces toxytricini 11th Intern. Symp. on the Genetics of Ind. Microorg. (GIM 2010), Melbourne, Australia (Jun. 2010) 157. J. Y. Hwang, N. P. K. Hanh, J. C. Yoo, C. N. Seong, and D. H. Nam The Biosynthetic Gene cluster for a Polyether Antibiotic, Laidlomycin, from Streptomyces sp. KCTC 10631BP 14th Intern. Biotechnol. Symp. (IBS2010), Rimini, Italy (Sep. 2010) 158. K. T. Nam, B. R. Sedai, and D. H. Nam Confirmation of O-Methyltransferase Genes in Macrolide Biosynthesis Gene Cluster of Streptomyces sp. KCTC BP0041 14th Intern. Biotechnol. Symp. (IBS2010), Rimini, Italy (Sep. 2010) 159. K. T. Nam, B. G. Kim, and D. H. Nam Production of O-Desmethylchalcomycins by Gene Inactivation for Macrolide Biosynthesis in Streptomyces Sp. KCTC BP0041 2010 Intern. Meetings of Fed. of Korean Microbiol. Soc., Seoul, Korea (Oct. 2010) 160. J. Y. Hwang, B. G. Kim, H. S. Kim, and D. H. Nam Analysis of Gene Cluster for Plecomacrolide Antibiotic Biosynthesis in Kitasatospora cheerisanensis KCTC2395 2011 Intern. Meeting of Microbiol. Soc. of Korea, Gwangju, Korea (May 2011) 161. J. Y. Hwang, B. G. Kim, S. H. Kim, and D. H. Nam Putative Biosynthetic Pathway of Bafilomycin in Kitasatospora cheerisanensis KCTC2395 2011 Intern. Meeting of Microbiol. Soc. of Korea, Gwangju, Korea (May 2011) 162. J. Y. Hwang, B. G. Kim, and D. H. Nam Organization of Gene Cluster for Bafilomycin Biosynthesis in Kitasatospora cheerisanensis KCTC2395 Bergey’s Inaugur. Intern. Symp. on Microb. Systematics. Beijing, China (May 2011) 163. D. H. Nam, J. Y. Hwang, S. H. Kim, and B. G. Kim Organization of Bafilomycin Biosynthetic Gene Cluster from Kitasatospora cheerisanensis KCTC2395 Meetings of 3 Divisions of Intern. Union of Micorbiol. Soc. (IUMS) 2011, Sapporo, Japan (Sep. 2011) 164. D. H. Nam, N. P. K. Hanh, H. S. Kim, and J. S. Lee Production of 14-Membered Macrolide Antibiotic by Deletion of Polyketide Synthase in Streptomyces Strain. Meetings of 3 Divisions of Intern. Union of Micorbiol. Soc. (IUMS) 2011, Sapporo, Japan (Sep. 2011) 165. D. H. Nam, B. R. Park, and A. Khanal The Biochemical Characterization of Two Acyl-CoA Carboxylase Complex in Streptomyces toxytricini. Meetings of 3 Divisions of Intern. Union of Micorbiol. Soc. (IUMS) 2011, Sapporo, Japan (Sep. 2011) 166. D. H. Nam Suggestion of Assurance of High-Tech Biopharmaceuticals. 2011 Fall Meeting of Kor. Soc. for Pharmacoepidemiol. & Drug Management, Busan, Korea (Oct. 2011) 167. J. Y. Hwang, N. P. K. Hahn, and D. H. Nam The Full Nucleotide Sequence of Biosynthetic Gene Cluster for Laidlomycin, a Polyether Antibiotic from Streptomyces sp. KCTC 10631BP 2012 Intern. Microbiol. Soc. of Korea, Seoul, Korea (May 2012) 168. H. S. Kim, J. Y. Hwang, and D. H. Nam Screening of Bafilomycin Biosynthetic Gene Cluster of Streptomyces griseus DSM 2608 2012 Intern. Meeting of Microbiol. Soc. of Korea, Seoul, Korea (May 2012) 169. S. H. Kim, J. Y. Hwang, Y. J. Cho, J. S. Chun, and D. H. Nam Genome Draft of Kitasatospora cheerisanensis KCTC 2395 Producing a Plecomacrolide Antibiotic Bafilomycin. 2012 Intern. Meeting of Microbiol. Soc. of Korea, Seoul, Korea (May 2012) 170. J. Y. Hwang, N. P. K. Hahn, and D. H. Nam Cloning and Confirmation of Laidlomycin Biosynthetic Gene Cluster in Streptomyces sp. KCTC 10631BP 15th Intern. Biotechnol. Symp. (IBS2012), Daegu, Korea (Sep. 2012) 171. H. S. Kim, J. Y. Hwang, and D. H. Nam Cloning and Confirmation of Plecomacrolide Biosynthetic Gene Cluster in Streptomyces griseus DSM 2608 15th Intern. Biotechnol. Symp. (IBS2012), Daegu, Korea (Sep. 2012) 172. S. H. Kim, J. Y. Hwang, and D. H. Nam The Full Nucleotide Sequence of Bafilomycin Biosynthetic Gene Cluster from Kitasatospora cheerisanensis KCTC 2395 2012 Intern. Meetings of Fed. of Korean Microbiol. Soc., Seoul, Korea (Oct. 2012) 173. D. H. Nam Strategy against Nagoya Protocol in the Field of Food and Drug 2012 Fall Intern. Conv. of Pharm. Soc. of Korea, Seoul, Korea (Oct. 2012) 174. J. H. Kim, D. W. Lee, S. K. Ku, D. H. Nam, D. S. Ryu, J. S. Kim, E-S. Do, H. G. Park, S. W. Jang, M. W. Son, H. G. Choi, C. S. Yong, and J. O. Kim Development of Hydrocolloid Wound Dressing Containing Anti-septic Drug, Benzalkonium Chloride 2012 AAPS Annual Meeting and Exposition, Chicago, USA (Oct. 2012) Technical Reports 1. S. C. Kim, J. H. Chung, K. Y. Ko, D. H. Nam, and B. M. Lee Organic synthesis of pesticide - Padan BSR - 5, Korea Research Institute of Chemical Technology (1980) 2. E. C. Cho, D. H. Nam, and J. H. Kim Performance of immobilized yeast cell reactor system for ethanol prouction Esoo Chemical Co., Ltd. (1984) 3. H. J. Lee, B. C. Park, J. H. Koh, S. T. Kwon, D. H. Nam, M. H. Kim and D.-S. Lee A study on human insulin production(II) BSN 7036-94-1, Korea Adv. Inst. Sci. Technol. (1988) 4. J. H. Koh, M. H. Kim, D. H. Nam, and D.-S. Lee A study on biochemical recombination of peptides BSE 7025-116-1, Korea Adv. Inst. Sci. Technol. (1989) 5. E. S. Shin, J. H. Bang, and D. H. Nam Ethanol production from whey (I) 901C201-350FP, Korea Ministry of Energy and Resources (1991) 6. J. H. Bang, S. Y. Lee, J. W. Rho, C. H. Lee, S. A Yang, and D. H. Nam Ethanol production from whey (II) 911C201-350FP1, Korea Ministry of Energy and Resources (1992) 7. D. H. Nam Biosynthetic Pathway of β-Lactam Antibiotics in Lysobacter lactamgenus 901-0407-035-2, Korea Science and Engineering Fund (1992) 8. S. B. Lee, J. H. Seo, D. H. Nam, and J. M. Park Characterization and Optimization of Recombinant Cell Culture Processes 90-0300-04, Korea Science and Engineering Fund (1993) 9. C. H. Yang, S. K. Lee, B. J. Lee, M. U. Choi, H. M. Roh, S. W. Seo, D. H. Nam, E. Y. Choi, and K. J. Kim New Drug Development by Protein and Enzyme Research Ministry of Health and Welfare, Korea (1994) 10. D. H. Nam, K. Huh, and C. S. Yong Studies on Defense Mechanisms Against Oxidative Stresses Korea Academic Promotion Fund (1995) 11. K. S. Lee, Y. C. Woo, D. H. Kim, D. H. Nam, C. H. Ahn, J. K. Kim, K. Y. Han, D. H. Lee, S. K. Kim, Y. H. Kim, H. J. Song, J. H. Chu, and C. S. Kang Development of New Ozone Generator Ministry of Commerce and Industry, Korea (1996) 12. D. H. Nam Molecular Cloning and Characterization of the Gene for Enzyme Responsible to the Synthesis of Semisynthetic β-Lactam Antibiotics from Xanthomonas citri GE185, Korea Academic Promotion Fund (1996) 13. D. H. Nam, J. M. Kim, S. W. Kim, J. K. Lee, S. M. Lee, and M. J. Kim Improvement of Ethanol Productivity by Protecting Yeast Cells from Oxygen Toxicity BE-D-03, Korea Academic Promotion Fund (1996) 14. D. H. Nam Cloning and Characterization of Cephem Biosynthetic Gene from Lysobacter lactamgenus 951-0503-008-2, Korea Science and Engineering Fund (1997) 15. D. H. Nam In vitro Allergenicity Test for Genetically-Modified Foods by Cell Culture Korea National Institute of Toxicology (2000) 16. D. H. Nam In vitro Allergenicity Test for Recombinant Proteins in Genetically-Modified Foods Korea National Institute of Toxicology (2001) 17. D. H. Nam, K. H. Lee, and H. S. Chang Bioequivalence Test of Sinil “Perinal®” Tablet Sinil Pharmaceutical Company (2002) 18. D. H. Nam, K. H. Lee, and H. S. Chang Bioequivalence Test of Shinpoong “Dompil®” Tablet Shinpoong Pharmaceutical Company (2003) 19. D. H. Nam Engineered Biosynthesis of Hybrid Macrolide Antibiotics through Genetic Manipulation 2000-2-21100-001-3, Korea Science and Engineering Fund (2003) 20. D. H. Nam Molecular Identification of Medicinal Mushrooms 04082NAT523, Korea Food and Drug Administration (2004) 21. D. H. Nam, S. D. Kim, J. Y. Kim, J. S. Lee, and H. G. Choi Development of Functional Bio-Food for Improving Gastrointestinal Function Using Chinese Yam (Dioscorea batatas) Flour A03-11-006, Government of Kyoungsangbuk-do Province (2005) 22. S. K. Lim, J. S. Lee, S. H. Lee, D. H. Nam. J. Y. Kim, and J. C. Park Development of Detoxicative and Hepatoprotective Agent for Alcoholic Hangover from Fresh Cheongdo Water Dropworts. 100153953, Ministry of Industry and Resources (2006) 23. D. H. Nam Development of Novel Microbial Metabolites Based on Lipstatin Biosynthetic Gene Cluster R01-2003-000-10387-0, Korea Science and Engineering Fund (2006) 24. D. H. Nam, J. S. Lee, A. V. Demirev, B. Sedai, and B. G. Kim Microbial Reconstruction for the Production of Ketolide Antibiotics MG05-0309-7-0, Microbial Genomics and Application Center (2008) 25 H.J. Kim and D.H. Nam Study for improving the criteria of the approval and evaluation of bio-generic drugs 07102BIOT393, Korea Food and Drug Administration (2008) 26. D.H. Nam and H.J. Kim Biosafety Assessment of Living Modified Organisms (LMO) Used for Biotechnological Medicines 07102BIOT400, Korea Food and Drug Administration (2008) 27. D.H. Nam Functional Characterization of Streptomyces Propionyl-CoA Carboxylase Involved in Secondary Metabolite Production 2009-0071085, Korea Research Fund (2009) 28. H.J. Kim and D.H. Nam Comparartive Survey for Quality Criteria of Biopharmaceutical Drugs for the Korean Pharmacopoeia Registry 12172BIOS303, Korea Food and Drug Administration (2012) 29. D. H. Nam DB Model Development and Legislative Measure Study According to Nagoya Protocol 12032POLR811, Korea Food and Drug Administration (2012) Patents 1. D.-S. Lee, H. O. Park, M. H. Kim, and D. H. Nam Methods for DNA Extraction from Fish Sperm Cells Korea Opening Patent, file no. 10-1987-0015571, register no. 10-0035973 (1990. 9.) 2. D.-S. Lee, B. C. Park, H. S. Lim, M. H. Kim, and D. H. Nam Production of Human Insulin from Newly-Designed Human Insulin Gene by Using Genetic Engineering Technique Korea Opening Patent, file no. 10-1988-0001498, register no. 10-0035971 (1990. 9.) 3. D.-S. Lee, H. O. Park, and D. H. Nam Facile Manufacturing Process for Phosphoramidites Used in DNA Synthesis Korea Opening Patent, file no. 10-1988-0008654, register no. 10-0046578 (1991. 12.) 4. D. H. Nam and S. K. Lim Novel Strain Streptomyces Sp. YU-100 Producing Extracellular Phospholipase D and Use Thereof Korea Opening Patent, file no. 10-2002-031415-9 (2002) register no. 10-0444948 (2004. 8) 5. D. H. Nam, S. D. Kim, K. O. Shin, J. Y. Kim, and S. K. Lim Food Composition Comprising Fermented Dioscorea batatas Decne, and The Rhizoma thereof with Lactic Acid for Preventing and Improving Constipation and Obesity Korea Opening Patent, file no. 10-2005-0111088 (2005) register no. 10- 0716123 (2007. 5.) 6. D. H. Nam, S. D. Kim, K. O. Shin, J. Y. Kim, and S. K. Lim Food Composition Comprising Fermented Dioscorea batatas Decne, and The Rhizoma thereof with Lactic Acid for Preventing and Improving Constipation Korea Opening Patent, file no. 10-2007-0001293 (2007), register no. 10-0707707 (2007. 4.) 7. J. Y. Kim, D. H. Nam, S. H. Lee, J. C. Park, K. H. Kim, and S. K. Lim A Composition Having Protective Function from Alcoholic Hangover Comprising an Extract of Dropwarts as Active Ingredient and Functional Healthy Food Using the Same Korea Opening Patent, file no. 10-2005-0102442 (2006)