Vaccine Overview 1. Which of the following demonstrates passive immunity? a. b. c. d. 2. The immune response to live-attenuated influenza vaccine The immune response to inactivated influenza vaccine The immune response of a neonate to hepatitis B vaccine The immune status of a neonate due to maternal influenza vaccine A 3 year old boy presents to your practice as a new patient. You want to confirm his vaccinations. The best initial plan is: a. Presume he has never been immunized and start his vaccine series. b. Assume the child is up-to-date since he was in daycare previously. c. Administer varicella today since he most likely did not get a booster. d. Access the Immunization Information System for your state. 3. Which of the following persons should NOT get nasal live-attenuated influenza vaccine? a. A 30 year old pregnant woman b. A 3 year old boy with an episode of wheezing with bronchitis 2 years ago c. A 4 year old healthy girl d. A 42 year old nurse 4. Which of the following persons should not get a varicella vaccine? a. A 27 year old school teacher who has never had chickenpox and is contemplating pregnancy in 3-6 months. b. A 52 year old daycare worker who can’t remember if she had chickenpox c. A 15 year old girl who had varicella vaccine at age 5 d. A 10 year old boy who had a non-vesicular rash when his brother had chickenpox AFMRD Presents: A Comprehensive Immunization Curriculum for Family Medicine Residency Programs 5. Which of the following is a rare occurrence after vaccination? a. b. c. d. 6. Redness and swelling at injection site Mild fever Anaphylaxis Injection site pain Which of the following vaccines should be postponed if a patient is on chemotherapy for leukemia? a. b. c. d. MMR Varicella Live-attenuated influenza All of the above Match the information you are seeking with the most appropriate website to find the information. 7. 8. 9. 10. 11. a. b. c. d. e. ____General immunization information ____Travel vaccine information ____Descriptions of pediatric vaccines ____Where to access a state vaccine registry ____How to report your observed adverse reaction to a vaccine http://wwwnc.cdc.gov/travel/yellowbook/search.aspx http://www.cdc.gov/vaccines http://www.cdc.gov/vaccines/programs/iis/contact-state.htm http://www.cdc.gov/vaccines/pubs/pinkbook/pink-chapters.htm http://vaers.hhs.gov/esub/index AFMRD Presents: A Comprehensive Immunization Curriculum for Family Medicine Residency Programs Vaccine Overview Answers 1. d. Passive immunity occurs with the transfer of antibodies to humans. The most common example is the transfer of maternal antibodies through the placenta to the neonate. 2. d. Each state has an Immunization Information System to record immunizations for children. 3. a. Pregnancy is a contraindication for live-vaccines. Under the age of 5, a child with one or more episodes of wheezing during the past year should not get live-attenuated influenza vaccine (LAIV – nasal spray). However, a child who had an episode of wheezing with bronchitis more than 1 year ago can receive LAIV. 4. b. A 52 year old is born prior to 1966, and thus is assumed immune to varicella. 5. c. Anaphylaxis is a rare occurrence after vaccination. 6. d. All live vaccines are contraindicated in immunocompromised patients, such as this patient on chemotherapy for leukemia. 7. b. General immunization information – www.cdc.gov/vaccines 8. a. Travel vaccine information – www.cdc.gov/travel/yellowbook/search.aspx 9. d. Descriptions of pediatric vaccines – www.cdc.gov/vaccines/pubs/pinkbook/pink-chapters.htm 10. c. Where to access a state vaccine registry – www.cdc.gov/programs/iis/contact-state.htm 11. e. How to report your observed adverse reaction to a vaccine http://vaers.hhs.gov/esub/index AFMRD Presents: A Comprehensive Immunization Curriculum for Family Medicine Residency Programs