EXPERTISE Computing Neural Networks Multimedia & information extraction GRID Computing Language engineering Contacts Framework 6 at Surrey fp6@eim.surrey.ac.uk http://www.computing.surrey.ac.uk Bioinformatics Gene expression Metabolomics Immunology Bioproduct physiology Bioelectronics SELECTED PUBLICATIONS C. Avignone Rossa, J. White, A. Kuiper, P. W. Postma, M. Bibb and M. J. Teixeira de Mattos (2002) Carbon Flux Distribution in AntibioticProducing Chemostat Cultures of Streptomyces lividans, Metabolic Engineering, 4 138-150 Samantha Kirk, Claudio A. Avignone-Rossa, Michael E. Bushell. (2000) Growth limiting substrate affects antibiotic production and associated metabolic fluxes in Streptomyces clavuligerus . Biotechnology Letters 22 pp. 1803-1809 Ahmad, Khurshid, Vrusias, Bogdan & Tariq, Mariam. (2002). Cooperative Neural Networks and 'Integrated' Classification. Proceedings of IJCNN'02, Honolulu, USA, 2002. Lee Gillam, Khurshid Ahmad, David Dalby, Chris Cox (2002) Knowledge Exchange and Terminology Interchange: the role of standards. In proceedings of ASLIB T&C 24. ISBN 0 85142 476 7 Lee Gillam, Khurshid Ahmad and Andrew Salway (2002) Digital Heritage and the use of Terminology. In Proceedings of TKE 2002 ISBN 2-7261-1217-X Principal Contact Department of Computing School of Biomedical and Life Sciences Professor Khurshid Ahmad (Comp) k.ahmad@surrey.ac.uk Research Contacts Lee Gillam (Comp) l.gillam@surrey.ac.uk Professor J McFadden (Bio) j.mcfadden@surrey.ac.uk Claudio Avignone-Rossa (Bio C.Avignone-Rossa@surrey.ac.uk Brendan Howlin (Bio) B.Howlin@surrey.ac.uk University of Surrey Guildford Surrey, GU2 7XH, UK Tel: +44 1483 686058 Fax: +44 1483 686051 Collaboration in 6th Framework Projects COMPUTING PROJECTS Generic Information Decision Agent (EU). The link between numerical data and language is explored for financial market analysis. Industrial partners: Finsoft, Ibermatica, JRC. Contact: Khurshid Ahmad http://www..computing.surrey.ac.uk/ai/gida/ Television In Words (EPSRC) Information extraction from textual, audio and film descriptions. Customized audio descriptions for young and old, and for different languages. In association with BBC, RMB, ITFC, Softel. Contact: Andrew Salway. http://www..computing.surrey.ac.uk/ckm/tiwo_project/Index.html Scene Of Crime Information System (EU) Automatically indexing scene of crime images through the link between photographs of crime scenes and the language used by police investigators to describe them. In association with 5 major UK Police Forces Contact: Khurshid Ahmad. http://www..computing.surrey.ac.uk/ai/socis/index.html Associated Projects Language Typology Resource Centre (EU) FUNCTIONAL GENOMICS Identification of collaborative opportunities within UK and EU research frameworks During the last decade, the UK research councils have generously funded activities exploring the human genome and producing gene sequences for over 30 micro-organisms. Funding landscapes of the EPSRC, BBSRC, and MRC, indicate that future opportunities lie in the exploitation of genome data for the production of antibiotics or for improving therapeutic regimens functional genomics is the umbrella term used for these activities. Functional genomics involves novel ways of efficiently retrieving and processing large volumes of data (genome sequences) on which microbial scientists can test hypotheses relating to innovative bioprocesses or therapeutic regimens. The efficient retrieval and processing of such large volumes of data provides an ideal problem-domain for applications of the emergent Grid (or Internet II) that the EPSRC/DTI sponsored eScience Centres are keen to fund. Searching the genome sequence and bioprocess data involves substantial use of search engines geared specifically to genomic data, which may involve the use of computing techniques such as data mining, information extraction and neural networks. Representation of bio-processes is an area of keen interest in artificial intelligence – most of the reported US activities in (post-) genomic sciences rely on representation of metabolic networks. COMPUTING RESEARCH AREAS Information Extraction The Department of Computing is engaged in research in extracting information from specialist texts. This research will improve the timeliness and quality information that is crucial for decisions in an enterprise. Recently, the focus has been on generating reports about financial markets using information extraction, time series analysis and neural computing (GIDA). Further research in information extraction, text summarisation and neural computing techniques, coupled with morphological and lexical techniques, give our demonstrator a unique edge. These techniques are highly adaptable to analysis of genomic and metabolomic data Multimedia Text-based understanding of still and moving images is essential for managing large collections of such data. (SOCIS, TIWO). Work with five UK Police Forces has led to the development of a system to automatically index images gathered at a scene of crime based on (spoken) descriptions of crime scene officers. Work with UK TV enterprises is focussed on the audio description of moving images. Both projects can significantly contribute to the understanding and representation of bioprocesses..