M EDICINE AND P HARMACOLOGY : D RUG U SE I N P REGNANCY
Peer Reviewed Publications
1. Gilstrap LC, Little BB , Klein VR. Antibiotic use during pregnancy. Advances in Infectious
Disease . 1987;1:1-9.
2. Little BB , Snell LM, Palmore MK, et al. Cocaine use in pregnant women in a large public hospital. American Journal of Perinatology . 1988;5:206-207.
3. Little BB , Snell LM, Gilstrap LC. Methamphetamine abuse during pregnancy: outcome and infant effects. Obstetrics and Gynecology . 1988;72:541-544.
4. Little BB , Snell LM, Klein VR, et al. Cocaine abuse during pregnancy: maternal and fetal implications. Obstetrics and Gynecology . 1989;73:157-160.
5. Little BB , Gilstrap LC. Cardiovascular drugs during pregnancy. Clinical Obstetrics and
Gynecology. 1989;32:13-20.
6. Little BB , Bawdon RE, Christmas JT, et al. Pharmacokinetics of zidovudine (AZT) during late pregnancy in Long Evans rats. American Journal of Obstetrics and Gynecology . 1989;161:732-
734.
7. Little BB , Snell LM, Gilstrap LC, et al. Alcohol abuse during pregnancy: changes in frequency in a large urban hospital. Obstetrics and Gynecology . 1989;74:547-550.
8. Little BB , Snell LM, Gilstrap LC, et al. Effects of T's and Blues abuse during pregnancy on maternal and infant health status. American Journal of Perinatology . 1990;7:359-362.
9. Little BB , Snell LM, Gilstrap LC, et al. Patterns of substance abuse during pregnancy: implications for the mother and fetus. Southern Medical Journal . 1990;83:507-509 and 518.
10. Little BB , Snell LM, Klein VR, et al. Maternal and fetal effects of heroin addiction during pregnancy. Journal of Reproductive Medicine . 1990;35:159-162.
11. Friedman JM, Little BB , Brent RL, et al. Potential human teratogenicity of frequently prescribed drugs. Obstetrics and Gynecology . 1990;75:594-599.
12. Leveno KL, Little BB , Cunningham FG. National impact of tocolytic therapy on low birth weight.
Obstetrics and Gynecology . 1990;76:12-15.
13. Little BB , Snell LM, Gilstrap LC, et al. Failure to recognize fetal alcohol syndrome in newborn infants. American Journal of Diseases in Children . 1990;144:1142-1146.
14. Roe DA, Little BB , Bawdon RE, et al. Metabolism of cocaine by human placentae: implications for fetal exposure. American Journal of Obstetrics and Gynecology . 1990;163:713-718.
15. Harstad TH, Little BB , Bawdon RE, et al. Embryocidal and teratogenic effects of pentamidine isethionate administered to pregnant Sprague-Dawley rats. American Journal of Obstetrics and
Gynecology . 1990;163:912-916.
16. Little BB , Snell LM, Wendel LC, et al. Prevalence of HIV in pregnant intravenous drug users in
Dallas, Texas. Texas Medicine . 1991;87:81-83.

17. Little BB , Snell LM. Brain growth among fetuses exposed to cocaine in utero : asymmetric growth retardation. Obstetrics and Gynecology . 1991;77:361-364.
18. Little BB , Harstad TH, Bawdon RE, et al. Pharmacokinetics of pentamidine in late pregnant
Sprague-Dawley rats. American Journal of Obstetrics and Gynecology . 1991;164:927-930.
19. Little BB , Knoll KA, Ghali FE, et al. Heroin abuse during pregnancy: effects on perinatal outcome and early childhood growth. American Journal Human Biology . 1991;3:463-468.
20. Little BB , Santos-Ramos R, Newell JF, et al. Megadose carbamazepine during embryogenesis.
Obstetrics and Gynecology . 1993;82:705-708.
21. Ramin SM, Little BB , Trimmer KJ, et al. Methamphetamine use during pregnancy in a large urban population. Journal of Maternal-Fetal Medicine . 1994;3:101-103.
22. Christmas JT, Little BB , Knoll KA, et al. Teratogenic and embryocidal effects of zidovudine in
Sprague-Dawley rats. Journal of Infectious Diseases in Obstetrics and Gynecology . 1995;2:223-
227.
23. Little BB , Wilson GN, Teasley TC, et al. Fetal alcohol syndrome: diagnosis, prevention, prognosis, and management. Dallas Medical Journal . 1995;81:21-25.
24. Stettler RW, Bohman VR, Little BB , et al. Metabolism of cocaine by cholinesterase during pregnancy: maternal and fetal activity. Journal of Maternal-Fetal Medicine . 1995;4:135-138.
25. Little BB , Roe DA, Stettler RW, et al. A new placental enzyme in the metabolism of cocaine: an in vitro animal model. American Journal of Obstetrics and Gynecology . 1995;172:1441-1445.
26. Little BB , Vanbeveren TT. Placental transfer of selected substances of abuse. Seminars in
Perinatology. April 1996;20(2):147-153.
27. Little BB , Jackson G, Wilson GN. Is there a cocaine syndrome? Teratology . 1996;54:145-149.
28. Aguila-Nelson N, Little BB , Ho RY, et al. Differential potencies of cocaine and its metabolites and benzoylecgonine, in suppressing the functional expression of somatostatin and neuropeptide Y producing neurons in cultures of fetal cortical cells. Biochemical Pharmacology . 1997;54:491-500.
29. Little BB . Immunosuppressant therapy during gestation. Seminars in Perinatology . 1997;21:143-
148.
30. Yonkers KA, Little BB , March D. Lithium use during pregnancy: a controversy. CNS Drugs.
1998;9:261-269.
31. Little BB , Snell LM, Trimmer KJ, et al. Peripatum cocaine use and adverse pregnancy outcome.
American Journal of Human Biology . 1999;11:598-602.
32. Little BB . Pharmacokinetics during pregnancy: evidence-based maternal dose formulation.
Obstetrics and Gynecology . 1999;93(51001):858-868.
33. VanBeveren TT, Little BB , Spence MJ. Effects of prenatal cocaine exposure and postnatal environment on child development. American Journal of Human Biology . 2000;12:382-387.
34. Snell LM, Van Beveren TT, et al. Treatment of substance abuse during pregnancy and infant outcome. American Journal of Perinatology . July 2003;20(5):255-262.

Book Chapters
1. Little BB, Gilstrap LC, Cunningham FG. Medications in pregnancy: Part I. Concepts of human teratology. In: Williams Obstetrics . Supplement 10. 18 th (1989) ed. Norwalk, CT: Appleton and
Lange; 1991:15 pp.
2. Gilstrap LC, Little BB , Cunningham FG. Medications in pregnancy: Part II. Special considerations. In: Williams Obstetrics . Supplement 11. 18th (1989) ed. Norwalk, CT:Appleton and Lange; 1991:15 pp.
3. Little BB . The effect of maternal cocaine use during pregnancy on intrauterine development. In:
American Psychological Association Monograph, Georgetown University Child Development
Center. Mothers, Infants and Substance Abuse . Washington, D.C.: Georgetown University
Medical Sschool; 1991:6-33.
4. Gilstrap LC, Little BB . Medication during pregnancy: maternal and embryofetal considerations.
In: James DK, Steer PJ, Weiner CP, Gonik B eds. High Risk Pregnancy: Management Options .
London: W.B. Saunders; 1994:229-252.
5. Little BB . Medication during pregnancy. In: James DK, Steer PJ, Weiner CP, Gonik B eds. High
Risk Pregnancy: Management Options . London: W.B. Saunders; 1999:617-638.
6. Little BB. Medication during pregnancy. In: James DK, Steer PJ, Weiner CP, Gonik B eds. High
Risk Pregnancy: Management Options . 3rd ed. London:W.B. Saunders; 2006: Chapter 36.
Books Written
1. Gilstrap LC, Little BB . Drugs and Pregnancy . 1st edition. New York, New York: Elsevier Press;
1992: 33 chapters, 472 pages.
2. Gilstrap LC, Little BB . Drugs and Pregnancy . 2nd edition. New York, New York: Chapman and
Hall; 1998: 34 chapters, 523 pages.
3. Little BB . Drugs and Pregnancy . 3rd edition. Cambridge, MA: Oxford University Press; 2006.