TRANSLATIONAL RESEARCH COMMITTEE
MINUTES
NOVEMBER 14, 2008 – LIVERPOOL, UK
Attendance
David Gershenson - dgershen@mdanderson.org
Els Berns - p.berns@erasmusmc.nl
Maria van der Burg - m.e.l.vanderburg@erasmusmc.nl
Jose Antonio Lopez Guerrero - jose.a.lopez@uv.es
Gokhan Tulunay - TBD
Ralf Butzow - ralf.butzow@hus.fi
Felix Hilpert - fhilpert@email.uni-kiel.de
Nobuyuki Susumu - susumu35@sc.itc.keio.ac.jp
Brigitte Miller - bemiller@wfubmc.edu
Ken Swenerton - kswener@bccancer.bc.ca
Mi-kyung - ???
Woong-Shick Ahn - ahnws@catholic.ac.kr
James D. Brenton - james.brenton@cancer.org.uk
Aikou Okamoto - aikou@jikei.ac.jp
Hani Gabra - h.gabra@imperial.ac.uk
Katherine Y. Look - look_katherine_y@lilly.com
GOG
EORTC
EORTC
GEICO
TRSGO
NSGO
AGO-OVAR
JGOG
RTOG
NCIC CTG
KGOG
KGOG
SGCTG
JGOG
SGCIG
Eli Lilly
Summary
1.) Welcome new members and discussion of leadership change
2.) Review of new banking efforts within GCIG members
a. Multiple new trials planned including trials involving serial biopsies to obtain
specimens during/after therapy.
3.) Review of new translational science projects within GCIG members
a. Discussion of TGCA (US) and IGC projects. Multiple members participating
in these genome projects.
4.) Collaborative projects and direction of committee:
a. Provide TR proposals for GCIG trials
Extensive discussion about direction/function of committee. A consensus
developed for the committee to review and supply TR for GCIG trials. This will
require early input from this committee into these trials as they are being
developed. Agreement to create a formal process for TR to be inserted into trials.
b. Initiate GCIG bank based studies
Discussion focused on the type of project, which could be accomplished within
the GCIG. It was decided that projects focused on rare tumors (clear cell etc.) or
clinical questions requiring rare specimens such as recurrence or plat resistance.
Over the next few weeks, recommendations will be obtained from members via
e-mail as to specific projects with the goal being to establish a demonstration
project by next meeting.
c. Initiate database analysis project
Large scale expression profiling meta analysis utilizing Birrer/Bowtell results has
been initiated and this could be extended to other members as a GCIG
demonstration project. Multiple groups expressed interest and this will be
attempted over the next few months.
d. Agreement within committee to focus on one or two projects so as not to
become too diffuse.