Department of Paediatrics & Child Health UNIVERSITY OF CAPE TOWN ANNUAL RESEARCH DAYS 2013 ANNUAL RESEARCH DAYS 2015 Programme 27th & 28th October D3 Lecture Theatre, D Floor Red Cross War Memorial Children’s Hospital CPD Points Tuesday, 27 October 2015 Wednesday, 28 October 2015 4 points 7 points Please sign the attendance register on both days to claim your points. PROGRAMME AND CONTENTS PAGE Oral Presentations Page No. Tuesday, 27 October 2015 12H15 – 12H25 Welcome and Opening B Morrow 12H25 – 13H10 Keynote Address: “Research in the health sciences in South Africa.” C. Stefan Session 1: Chairperson: D Greenfield 13H15 – 13H30 Field evaluation of point-of-care testing for early infant diagnosis in Cape Town, South Africa. L. Dunning 13H30 – 13H45 HIV exposed very low birth weight (<1500g) infants: are they all really "high risk"? C. Levin 13H45 – 14H00 Vaccination of the preterm infant - is it feasible and safe? B. Louw 14H00 – 14H15 Bacteraemia in the neonatal unit at New Somerset Hospital: a retrospective record review of blood cultures, 2011 - 2014. W. Mabaso The influence of anaesthetic method on outcomes of preterm infants delivered by caesarean section in a tertiary hospital in South Africa: a pilot review. R. Stander 14H15 – 14H30 14H30 – 15H00 T E A & POSTERS Session 2: Chairperson: 15H00 – 15H15 15H15 – 15H30 15H30 – 15H45 R Ramesar Clinical outcome of MLPA testing for intellectual disability at Red Cross War Memorial Children's Hospital genetic clinic. K. Fieggen Frequency of selected SNPS associated with kidney disease amongst sickle cell disease patients in Africa. A. Geard Identification of genetic features underlying a rare childhood cancer syndrome: Constitutional Mismatch Repair Deficiency (CMMR-D) syndrome. L. Lamola 1 15H45 – 16H00 16H00 – 16H15 16H15 – 16H30 Investigating the prevalence of selected MYO7A mutations amongst a group of sub-Saharan African patients with nonsyndromic hearing loss. N. Manyisa Distribution of sickle cell disease-related genetic markers in malaria-free sub-Saharan African countries. K. Mnika Hydroxyurea induces γ-Globin expression through micro-RNAsmediated actions in primary erythroid and K562 cells. G. Pule Wednesday, 28 October 2015 Session 3: Chairperson: 08H30 – 08H45 S Naidoo A novel approach to ductal spasm during percutaneous device occlusion of patent ductus arteriosus. R. de Decker Increasing the efficiency of a paediatric cardiology clinic using simulation optimisation. C. van Niekerk Continuous flow peritoneal dialysis (CFPD) use in children with AKI and inadequate ultrafiltration on convention peritoneal dialysis (PD). P. Nourse 09H15 – 09H30 Pediatric lupus in South Africa: treatment and outcomes. C. Scott 09H30 – 09H45 A study of the aetiology and outcome of crescentic glomerulonephritis in children presenting to the Red Cross Children's Hospital. C. Mwaba Treatment of infants with epilepsy: common practice across the world. R. Burman Resolved lower limb muscle tone abnormalities in children with HIV encephalopathy receiving standard antiretroviral therapy. T. Mann 10H15– 10H30 Review of liver injuries in young children. A.B. van As 10H30 – 11H00 T E A & POSTERS 08H45 – 09H00 09H00 – 09H15 09H45 – 10H00 10H00– 10H15 Page No. Session 4: Chairperson: 11H00 – 11H15 B Eley The effects on proning on regional ventilation in children with acute respiratory distress syndrome (ARDS) or acute lung injury (ALI) - a pilot study. 2 B. Morrow 11H15 – 11H30 Chest radiographic abnormalities in HIV-infected African children – a longitudinal study. R. Pitcher 11H30 – 11H45 Clinical predictors of culture confirmed pulmonary tuberculosis (PTB) in a high TB and HIV prevalence area. L. Frigati Microbiological yield from induced sputum compared to oropharyngeal swab in young children with cystic fibrosis. M. Zampoli 11H45 – 12H00 12H00 – 12H15 The effect of body position on regional distribution of ventilation and muscle activity in mechanically ventilated infants and children. A. Lupton-Smith 12H15 – 12H30 Adenoviral pneumonia at Red Cross War Memorial Children's Hospital: a retrospective descriptive study reviewing the presentation, clinical course and outcomes of laboratory-confirmed adenovirus associated pneumonia at RCWMCH. Z. MukuddemSablay 12H30 – 12H45 Lung function in HIV-infected adolescents on antiretroviral therapy in Cape Town, South Africa. L. Githinji Risk factors for Bordetella pertussis disease in hospitalised children. R. Muloiwa 12H45 – 13H00 13H00 – 14H00 L U N C H (Venue: Tea Room, Johnson & Johnson Building, RXH) Session 5: Chairperson: 14H00 – 14H15 14H15 – 14H30 14H30 – 14H45 14H45 – 15H00 15H00 – 15H30 L Cooke Every child counts - lessons from the South African child death review pilot. S. Mathews Descriptive study evaluating the use of the Road to Health Card by doctors in a tertiary paediatric hospital setting. J. Wiles An evaluation of the impact of outreach and support child health services on level 2 and level 3 facilities. W. Breytenbach Faecal carriage of extended-spectrum beta-lactamase- and carbapenemase-producing enterobacteriaceae in healthy infants and their mothers, South Africa. R. Manenzhe T E A & POSTERS Session 6: Chairperson: 15H30 – 16H00 16H00 – 16H15 A Argent The Drakenstein Child Health Study: investigating the early determinants of child health in South Africa. H. Zar Streptococcus pneumoniae nasopharyngeal colonization, serotype distribution and impact of vaccination during the first year of life: a South African birth cohort study. F. Dube 3 16H15 – 16H30 Lung function in the first year of life in African infants: effect of early life pneumonia. L. Willemse 16H30 – 16H45 Incidence of childhood pneumonia: facility-based surveillance estimate compared to measured incidence in a South African birth cohort study. D. le Roux 16H45 – 17H00 Feedback on Research Day presentations, with Award & Research Prizes by Profs. D. & S. Hall Closing remarks by H Zar 4