Biography
Born April 30, 1944 in Split (Croatia). Citizen of Croatia and France; Resident of France. Married
to Danica Radman, ethnomusicologist, three children. Languages: Croatian, French, English,
German and Italian.
Studies and Positions. Undergraduate in experimental biology and physical chemistry, University of
Zagreb, Croatia; Ph.D. in 1969 from Department of Molecular Biology, University of Brussels,
Research assistant - Institute for Philosophy of Science and Peace Research. Zagreb. Post-doctoral
research fellow CNRS, Gif-sur-Yvette, France and Research Fellow with Prof. M. Meselson,
Harvard University (1969-73). Research Professor heading the Laboratory of Enzymology of DNA,
University of Brussels (1973-83). Research Director - CNRS, Institute Jacques Monod (University
Paris 7, Paris), Visiting Scientist, N.I.E.H.S. - N.I.H., USA. Since 1998 Professor of Cell Biology,
Medical School René Descartes – University of Paris 5 and Director of the INSERM research unit
U571“ Medical and evolutionary molecular genetics ”. Since 2004: Science Adviser to the Prime
Minister of Croatia.
Sites web:
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http://www.necker.fr/tamara/
http://www.fdv-paris.org/
http://www.medils.org
Honors, Awards, Memberships: 1979:"Antoine Lacassagne" Award, Grand Prix of the French
Ligue Against Cancer for the discovery of the mutagenic SOS system in bacteria. 1990: “Golden
Eureka of Innovation”. 1991: FEBS International Lecturer. 1992: “Charles Leopold Meyer” Grand
Prix of the French Academy of Science for the co-discovery of DNA error correction (mismatch
repair). 1992: Medal of Honour: Society for the Encouragement of Progress. 1998: Medal
"Spiridion Brusina" at the 100th anniversary of the Croatian Naturalists' Society. 1998: Grand Prix
"Leopold Griffuel" for the contributions to the field of DNA repair. 2000: Grand Prix "Richard
Lounsbery" - Joint Award of the French and U.S. national academies of science for the discovery of
mismatch repair as genetic barrier between related species. Science Award 2000 from the “U.S.
Environmental Mutagen Society” for “far-reaching research contributions to understanding the
profound consequences of mutation and recombination, in global genomic responses, DNA repair,
cancer and evolution”. 2000: “Katzir Katchalsky Honorary Lecturer”, Weizmann Institute, Israel.
2003: Grand Prix INSERM; Lecturer at the Celebration of the 50th anniversary of the discovery of
DNA structure (Roy. Soc. & CSHL); 2004: Leonardo Award for creativity in scientific research.
Member: EMBO (1978), Croatian Academy of Sciences and Arts (1992), Academia Europaea
(1998), French “Académie des Sciences” (2002) and a number of professional societies and
editorial boards of scientific journals.
Speaker at187 international. congresses, meetings and workshops, 41 plenary, keynote or closing
lectures, approx. 500 seminars worldwide.
Research: Over 170 publications in the areas of DNA repair, replication, mutagenesis, genetic
recombination, evolution of species and carcinogenesis. 3 discoveries present in molecular biology
textbooks; about 10.000 citations.
10 PUBLICATIONS MORE REPRESENTATIVE OF M. Radman:
(1) BABIC, A., LINDNER, A., VULIC, M., STEWART, E. & RADMAN, M. “Direct
visualisation of horizontal gene transfer” Science (2008) 319: 1533-37.
(2) ZAHRADKA, K. SLADE, D. BAILONE, A. SOMMER, S. AVERBECK, D., LINDNER AB
& RADMAN, M. “Reassembly of shattered chromosomes in Deinococcus radiodurans” Nature
(2006) 443: 569-573.
(3) TADDEI F., HAYAKAWA H., BOUTON M.F., CIRINESI A.M., MATIC I., SEKIGUCHI
M., & RADMAN M. Transcriptional errors caused by oxidative damage are counteracted by MutT
protein, Science (1997) 278,: 128-130
(4) TADDEI F., RADMAN M., MAYNARD-SMITH, J., TOUPANCE B., GOUYON P.H.,
GODELLE B. Role of mutator alleles in adaptive evolution, Nature (1997) 387,: 700-702.
(5) MATIC I., RAYSSIGUIER C., RADMAN M. Interspecies gene exchange in bacteria: The
role of SOS and mismatch repair systems in evolution of species". Cell (1995) 80, 507-515
(6) de WIND N., DEKKER M., BERNS A., RADMAN M., & te RIELE H. Inactivation of the
mouse Msh2 gene results in mismatch repair deficiency, methylation tolerance, hyperrecombination
and predisposition to cancer". Cell (1995) 8, 321-330
(7) JONES M., WAGNER R., RADMAN M. Mismatch repair and recombination in E. coli, Cell
(1987) 50, 621-626
(8) RAYSSIGUIER C., THALER D.S., RADMAN M. The barrier to recombination between
Escherichia coli and Salmonella typhimurium is disrupted in mismatch-repair mutants, Nature
(1989) 342: 396-401
(9) GLICKMAN B.W., RADMAN M., E. coli mutator mutants deficient in methylation
instructed DNA mismatch correction. Proc. Natl. Acad. Sci. USA (1980) 77, 1063-1067
(10) RADMAN M. “Phenomenology of an inducible mutagenic DNA repair pathway in E. coli:
SOS repair hypothesis". In "Molecular and environmental aspects of mutagenesis”, eds. L. Prakash,
F. Sherman, M.W. Miller, C.W. Lawrence and H.W. Taber (6th Rochester Conf. on Environmental
Toxicity, 1973) C.C. Thomas Publ., Springfield, Illinois (1974) 128-142.