THE BODY AGAINST DISEASE WEBQUEST How do bacteria cause problems in your body? Select this animation: **Pathogenic E. coli - View Online. Review the Basic Structure and Life Cycle before selecting Pathogenic and Non-Pathogenic E. Coli, Symptoms… and Prevention… (http://www.biology.ualberta.ca/facilities/multimedia/index.php?Page=289) Briefly describe the 3 different groups of E.Coli. 1. 2. 3. How do the toxins of the 2 different forms of enterovirulent E. Coli cause their specific problems? EHEC- ETEC- How do viruses cause disease? ***Read the info at: Commoncold.org / Understanding Colds/ How Infection Occurs http://www.commoncold.org/undrstn3.htm What do some viruses, like cold viruses, actually do to your cells? http://www.commoncold.org/undrstn4.htm Why do you get the typical symptoms of a cold? How Does The Body Fight Disease? The Immune System: What are the specific roles of each of the following in the non-specific and specific immune response? 1. http://nobelprize.org/educational_games/medicine/immunity/immune-overview.html 2. http://nobelprize.org/medicine/educational/immunity/immune-detail.html Complement System: Phagocytes: granulocytes- macrophages- dendritic cell- Helper T-Cell- Cytotoxic (Killer) T-Cell B- Cell / plasma cell How Do People Fight Disease? Vaccinations: http://users.rcn.com/jkimball.ma.ultranet/BiologyPages/V/Vaccines.html#table What is a vaccine? How does it work? How does it differ from “passive Immunity” You have already had at least 10 vaccinations! Which will you need in the future? Take the quiz and find out! http://www2.cdc.gov/nip/adultImmSched/ Pick 2 and explain what they protect against: (select each highlighted name). 1. 2. For a quick look at your recommended vaccines, check out the tables at: http://www.cdc.gov/mmwr/preview/mmwrhtml/mm5540a10.htm?s_cid=mm5540a10_e Should you be vaccinated against the HPV virus that causes cervical cancer? First, you need to learn a bit more about HPV and the vaccine. Go to: http://www.cancer.gov/cancertopics/understandingcancer/HPV-vaccine Watch the slides and answer the following: 1. How exactly does the HPV virus interfere with normal cell function? 2. How does the vaccine work? Use the following sites to gather some more information: http://www.cdc.gov/std/hpv/STDFact-HPV-vaccine-young-women.htm http://www.webmd.com/sexual-conditions/features/hpv-cervical-cancer-vaccine-15-facts http://www.gardasil.com/ Notes: Do you think you should get the vaccine? If you already have, would you recommend it to a friend? Why/ why not? How do antibiotics work? http://www.hhmi.org/biointeractive/Antibiotics_Attack/frameset.html Pathways of Attack : Briefly describe the 5 methods by which antibiotics work. Name one antibiotic that works by each method. 1. 2. 3. 4. 5. What actually makes a bacteria "resistant" to an antibiotic? http://www.hhmi.org/biointeractive/Antibiotics_Attack/frameset.html On the left, select: Antibiotic Resistance. Briefly explain: *role of plasmids *enzyme alteration *efflux pumps *target alteration http://www.tufts.edu/med/apua/Q&A/Q&A.html : read -About antibiotic resistance Be sure to explain in terms of mutation, variation, natural selection! Why do bacteria become resistant to antibiotics? How do bacteria become resistant? How does antibiotic resistance spread? Why is this a societal problem? http://www.tufts.edu/med/apua/Q&A/Q&A_soc.html http://www.cdc.gov/ncidod/dhqp/ar_mrsa_spotlight_2006.html