Biology 211 Exam 4 Study Guide Chapter 28 The Reproductive Systems INTRODUCTION 1. Define reproduction in terms of continuity of the population and cell division, and then generally classify the organs of reproduction by function. THE CELL CYCLE IN THE GONADS 2. Define meiosis. The number of Chromosomes in Somatic Cells and Gametes 3. Describe the different types and numbers of chromosomes that exist in somatic and sex cells (gametes) and the changes that occur as one evolves into other during meiosis. Meiosis 4. Describe the result of meiosis Meiosis I 5. Describe and explain the events of meiosis I. Meiosis II 6. Describe and explain the events of meiosis II. MALE REPRODUCTIVE SYSTEM 7. List the major components of the male reproductive system and their general functions. Scrotum 8. Explain the structure, histology, and functions of the scrotum in its role of protection and temperature regulator. Testes 9. Explain the structure, histology, and functions of the tunicas, seminiferous, tubules, spermatogonia and sustentacular cells of the testes. 10. Explain the blood-testis barrier. 11. Discuss cryptorchidism. Spermatogenesis 12. Discuss the key points relating to spermatogenesis. 13. Describe and explain the events of spermatogenesis and spermiogenesis. Sperm 14. Examine the functional structures of the spermatozoa. Hormonal Control of Spermatogenesis 15. Discus the negative feedback system of the brain-testicular axis that controls the production of sperm, with emphasis on the actions of each type of hormone with the different types of cells in the testes. Reproductive System Ducts in Males Ducts of the testis 16. Explain the structure, histology, and functions of the ducts of the testis. Epididymis 17. Explain the structure, histology, and functions of the epididymis. Ductus Deferems 18. Explain the structure, histology, and functions of the ductus deferens. Spermatic Cord 19. Describe the structures that constitute the spermatic cord and explain its passage through the inguinal canal. 20. Describe the course, treatment, and consequences of inguinal hernias. Ejaculatory Ducts 21. Explain the structure, histology, and functions of the ejaculatory ducts. Urethra 22. Explain the structure, histology, and functions of the urethra. Accessory Sex Glands Seminal Vesicles 23. Explain the structure, histology, and function of the seminal vesicles. Prostate Gland 24. Explain the structure, histology, and function of the prostate gland. Bulbourethral Glands 25. Explain the structure, histology, and function of the bulbourethral gland. Semen 26. Describe the origins as well as cellular and chemical characteristics of semen. Penis 27. Explain the structure, histology, and functions of the penis. 28. Describe the surgical procedure called circumcision and discuss its possible benefits. FEMALE REPRODUCTIVE SYSTEM 29. Describe the general location and functions of the ovaries, uterine (Fallopian) tubes, uterus, vagina, vulva, and mammary glands. Ovaries 30. Describe the external accessory structures related to the ovaries. Histology of the Ovary 31. Discuss the histology of the ovaries. Oogenesis 32. Follow the steps of oogenic meiosis that show the process of genetic division is the same as in spermatogenesis, but then emphasize that the timing, distribution of cytoplasmic materials and number of viable gametes at the end is very different. 33. Trace the formation and development of the various structures of the ovarian cycle Uterine Tubes 34. Describe the uterine tubes' general and epithelial structure, in addition to their operation in transport of the secondary oocyte after ovulation. Uterus 35. List the functions of the uterus. Anatomy of the Uterus 36. Identify the anatomical subdivisions of the uterus. 37. Point out the dimensions and major features of the uterus, and then show how the surrounding ligaments and membranes support the uterus. 38. Discuss uterine prolapse and identify the three degrees of uterine prolapse. Histology of the Uterus 39. Discuss the three histological layers of the uterus. 40. Provide a detailed histological examination of the endometrium. 41. Discuss the indications for a hysterectomy. 42. . Discuss the blood supply to the uterus. Cervical Mucosa 43. Discuss the composition of the cervical mucosa and correlate the changes in the cervical mucosa to its effects on the sperm. Vagina 44. Name the anatomic structures of the vagina. Vulva 45. Differentiate the functions of the distinct external structure of the vulva. Perineum 46. Indicate the supporting muscles of the perineum with orientation to the urogenital and anal triangles. 47. Explain the medical reasons for performing an episiotomy. Mammary Glands 48. Describe the location, anatomy, histology, and function of the mammary glands. 49. Describe fibrocystic disease of the breast in terms of cause and symptoms. FEMALE REPRODUCTIVE CYCLE 50. State the general purpose of the uterine and ovarian cycles. Hormonal Regulation of the Female Reproductive Cycle 51. Discuss the factors that stimulate and inhibit secretion of the hypothalamic, pituitary, and ovarian hormones, and then show the response of tissues that prepare the woman's system for reproduction. Phases of the Female Reproductive Cycle 52. Note the normal span of the sum of the three phases of the female reproductive cycle. Menstrual Phase 53. Portray the events occurring with the follicles in the ovaries and the tissue changes in the endometrium during the menstrual phase, and explain how these are part of reproductive preparation. Preovulatory Phase 54. Discuss the changes in hormone levels during the preovulatory phase that can be shown to promote the development of the follicle and oocyte in the ovaries and cellular modifications of the endometrium. Ovulation 55. Discuss the changes in hormonal feedback to the hypothalamus that initiates expulsion of the secondary oocyte during ovulation. Postovulatory Phase 56. Explain the consistency of the postovulatory interval and course of development of the corpus luteum and endometrium depending on whether fertilization does or does not occur. 57. Discuss various menstrual abnormalities. 58. Discuss the condition female athlete triad (disordered eating, amenorrhea, and premature osteoporosis) that often develops in women who train intensely. THE HUMAN SEXUAL RESPONSE 59. Define the general purpose of sexual intercourse. Stages of the Human Sexual Response 60. Describe the characteristic physical and physiological events of the four stages of sexual response. Changes in the Male 61. State the neural actions that promote erection and transport of semen during the four stages on the male sexual response. 62. Discuss the causes, signs, and treatment of erectile dysfunction. Changes in the Female 63. Describe the physiological basis of transudation and responses of the female system in the four phases of the sexual response. BIRTH CONTROL METHODS 64. Contrast the various types of birth control and their effectiveness: Surgical Sterilization Hormonal Methods Intrauterine Devices Spermacides Barrier Methods Periodic Abstinence Coitus Interruptus Induced Abortion DEVELOPMENT OF THE REPRODUCTIVE SYSTEM 65. Describe the development of the reproductive systems. 66. Discuss the effect of a deficiency of 5-alpha-reductase. AGING AND THE REPRODUCTIVE SYSTEM 67. Describe the general effects of aging on the reproductive systems during development to maturity. DISORDERS: HOMEOSTATIC IMBALANCE 68. Describe the symptoms and causes of male disorders (testicular cancer and prostate disorders) and female disorders (premenstrual syndrome, endometriosis, breast cancer, ovarian cancer, cervical cancer, and vulvovaginal candidiasis). 69. Explain the symptoms and causes of sexually transmitted diseases (STD's) such as chlamydia, gonorrhea, syphilis, and genital herpes MEDICAL TERMINOLOGY 70. Define medical terminology associated with the reproductive systems. Chapter 29 Development And Inheritance INTRODUCTION 1. Differentiate between embryological development and fetal development 2. List the three periods of prenatal development. EMBRYONIC PERIOD First Week of Development Fertilization 3. Describe the transport and stimulus for transformation of the sperm from introduction into the female reproductive tract through capacitation. 4. Define the conditions produced by the sperm to penetrate the three layers surrounding the secondary oocyte and the actions initiated when the first sperm merges with the ooctye. 5. Discuss the difference in the process that forms monozygotic versus dizygotic twins. Cleavage of the Zygote 6. Explain the process of cleavage and state how this process leads to the formation of a morula. 7. Discuss stem cell research and therapeutic cloning and the ultimate goals of these therapies. Development of the Blastocyst 8. Specify the features of the blastocyst that distinguish it from the morula and leads to differentiation of cells. Implantation 9. Discuss the cellular and structural transformations of the blatocyst and endometrium that allow the two to merge and then sustain their interactions. 10. Examine the changes in the endometrium (decidua) and list the three regions of the decidua. 11. Define an ectopic pregnancy and state the probable causes, symptoms, and treatments of an ectopic pregnancy Second Week of Development Development of the Trophoblast 12. Discuss the layers, which develop from the trophoblast and state their function. Development of the Bilaminar Embryonic Disc 13. Discuss the two layers that develop from the inner cell mass. Development of the Amnion 14. Examine the development of the amnion and the formation of the amniotic fluid and state their function. Development of the Yolk Sac 15. Discuss the formation and functions of the yolk sac. Development of the Sinusoids 16. Discuss the formation and significance of the sinusoids. Development of the Extraembryonic Coelom 17. Examine the process that leads to the formation of the extraembryonic coelom. Development of the Chorion 18. Discuss the formation and significance of the chorion. Third Week of Development Gastrulation 19. Describe gastrulation and the growth of the three primary germ layers. 20. Establish which organs arise form the different germ layers by the end of the embryonic development. Neurulation 21. Describe the process of neurulation and the formation of the neural tube. 22. Explain how the neural tube develops into the primitive nervous system. Development of Somites 23. Examine the formation of the somites and the three regions within the somite. Development of the Intraembryonic Coelom 24. Discuss the formation of the intraembryonic coelom and trace its development into the pericardial, pleural, and peritoneal cavities. Development of the Cardiovascular System 25. Discuss the formation of the primitive heart. Development of the Chorionic Villi and Placenta 26. Trace the development of the chorionic villi and placenta. 27. Explain the maternal and fetal parts of the placenta. 28. State the functions of the placenta. 29. Discuss the fate of the placenta after the birth of the baby. 30. Describe placenta previa and its consequences. Fourth Week of Development 31. Define the term organogenesis. 32. Examine how embryonic folding converts the embryo to a three dimensional cylinder. 33. Trace the organ development that occurs during the fourth week of development. Fifth Through the Eighth Weeks of Development 34. Describe the rapid development of the embryo, which occurs during this time. FETAL PERIOD 35. Discuss the development of the fetus, which occurs during this period. 36. Reference the pages indicated in the text that discuss the development of the various body systems. PRENATAL DIAGNOSTIC TESTS Fetal Ultrasonography 37. Describe a sonogram and type of information obtained. Amniocentesis 38. Discuss the timing of amniocentesis and the types of anatomical, cellular, genetic, and biochemical conditions that may be diagnosed with this method. Chorionic Villi Sampling 39. Discuss the timing, technique, and types of information derived from chorionic villi sampling. Noninvasive Prenatal Tests 40. Discuss the significance of maternal alphafetoprotein (AFP) test. MATERNAL CHANGES DURING PREGNANCY Hormones of Pregnancy 41. Compare the sources and functions of the hormones secreted during pregnancy. 42. Discuss how early pregnancy tests work. Anatomical and Physiological Changes During Pregnancy 43. Describe the relationship between maternal anatomical and physiological changes associated with gestation. 44. Discuss the cause and consequences of pregnancy-induced hypertension. EXERCISE AND PREGNANCY 45. Discuss the physical and temperature impact of exercise on the developing child and the various ways to compensate for and still gain the benefits of exercise. LABOR 46. Outline the hormonal and neural regulation of the duration of pregnancy. 47. Describe the characteristics of the three stages of labor. 48. Describe the conditions that may necessitate alternative means of delivery. ADJUSTMENTS OF THE INFANT AT BIRTH Respiratory Organs 49. Discuss the respiration system adjustments of the infant at birth. Cardiovascular Adjustments 50. Discuss the cardiovascular system adjustments of the infant at birth. 51. Discuss the problems faced by a premature baby. PHYSIOLOGY OF LACTATION 52. Discuss the hormonal and CNS physiology involved in control of lactation. 53. Provide information on the advantages of breast-feeding for both the mother and child. 54. Discuss the benefits of nursing accompanying childbirth. INHERITANCE 55. Define inheritance and the general basis of combining and transmitting traits. Genotype and Phenotype 56. Distinguish the basis of genotype from that of phenotype. 57. With regard to the human, specify the meaning of chromosomes, homologues, genes, and alleles. 58. Using an example of a hereditary disorder, demonstrate how genotypes of different combinations of dominant and recessive alleles are expressed as phenotypes. 59. Show how the probability of a particular genotype can be made using a Punnett square. 60. Discuss what happens to the genotype when disjunction occurs. Variations on Dominant-Recessive Inheritance 61. Discuss the interactions of genes and the environment that commonly lead to more complex expressions of a trait. Incomplete Dominance 62. Describe the genotypes and phenotypic expressions that can occur with sickle-cell disease. Multiple-Allele Inheritance 63. Describe how multiple alleles (three), when present in varying combinations of two (a genotype), can produce four blood types. Complex Inheritance 64. Examine the effects of two or more genes or the combined effects of many genes and environmental factors on inheritance. Autosomes, Sex Chromosomes, and Sex Determination 65. Discriminate autosomes from sex chromosomes and combinations of the latter that determine the physical sex of a child. 66. Explain the role of the SRY gene in determining gender. Sex-Linked Inheritance 67. Discuss the location of alleles on X and/or Y-chromosomes that can be illustrated to be the source of traits that are inherited differently for males and females. Red-Green Blindness 68. Show the ways in which the color-blind gene on the X chromosome can lead to different genotypes between men and women and consequently lead to distinct probabilities of acquiring a color-blind phenotype. 69. X-Chromosome Inactivation 70. Discuss the means and reasons for creation of a Barr body in the genome of women. Teratogens 71. Discuss the interactions of environmental conditions with genes that can change their expression. Chemicals and Drugs 72. Give examples of conditions associated with teratogenic changes of chemicals and drugs. Cigarette Smoking 73. Describe conditions that may result from cigarette smoking during different stages of development. Irradiation 74. Discuss how irradiation can effect genes and so produce mutations in different stages of pregnancy. DISORDERS: HOMEOSTATIC IMBALANCES 75. Define and discuss infertility, Down syndrome, and trinucleotide repeat diseases. MEDICAL TERMINOLOGY 76. Define medical terminology associated with development inheritance.