Home > Focus stories > Nutrigenomics > Food forensics Unit plan: Food forensics Overview Students create a database of the ingredients of food available in the school tuck shop so that people with dietary restrictions can easily access the information to make food choices that will be best for their health. Purpose To show the dimensions of a nutrigenomics-based solution and the mechanism by which this information can be managed (bioinformatics). This can be demonstrated by the development of a model system that provides information that can be used as the basis for dietary decision-making. Background Suggestions for a scenario The school committee has been given the job of promoting healthy food in the tuck-shop. They are aware that there are some students with particular food needs and realise that there is a need for a database that identifies the components of particular foods (e.g. milk-based products and vitamin enhanced drinks). Your problem is to develop a model system that will provide information for any student who is interested in structuring their diet to maximise their health. Where's the Biotechnology? At present, diets and foodstuffs can be developed to cater for groups of people with particular food requirements. In the future, personalised diets and products will be able to be designed for individuals. This is because different people respond differently to particular foods. They have different genes, and our genes affect the way our bodies deal with food (see focus story). Two people might have symptoms consistent with the same food-related condition, but respond differently to the same foods. The study of how food and genes interact is called nutrigenomics. Research is being carried out to identify food components that are particularly helpful / harmful for individuals, even though they might both have the symptoms of the same foodrelated condition. Bioinformatics is the use of computer systems to manage complex biological data. Although the genetic component of a food-related condition cannot be studied within the school context, students can think about the content of different foods and how this impacts on who can eat those foods. This programme provides an outline of ©2005-2009 The University of Waikato www.biotechlearn.org.nz Home > Focus stories > Nutrigenomics > Food forensics the range of information that needs to be considered when developing a personalised food / menu for a person with a particular food-related condition. Central to this activity is the development of a model system containing information about food products and food-related conditions that can be used for individual decision-making and the development of new products. Curriculum focus Technology The technological principles underpinning future dietary decisions will be based on knowledge about food content and nutrigenomics (how genes and foods interact). Bioinformatics enables the information to be accessed and used for decisionmaking. Ethical issues are important when dealing with personalised problem solving. Acknowledging and highlighting differences (cultural and medical) require ethical awareness and sensitivity, as does accessing and storing information about individuals. Science To develop an understanding of the relationship between structure and function in living organisms, for example: digestive system, nutrition and genetic diversity. Many food-related conditions are inherited and can affect lifestyle and dietary choices. Focus of skill & strategy Although nutrigenomics is a new area of biotechnological study, students will be able to recognise the science and technological solutions they are already using in health and food technology and be able to combine these areas of study to create a bioinformatics database. This system is used to provide data so that students (the ‘clients’) can make informed choices. This programme also provides students with an opportunity to identify a range of food-related reactions and how these affect people’s access to various foods. ©2005-2009 The University of Waikato www.biotechlearn.org.nz Home > Focus stories > Nutrigenomics > Food forensics UNIT PLAN: FOOD FORENSICS Suggested learning intentions Suggested learning experiences The following learning experiences will provide you with starting points for an exploration of this topic. You may decide to narrow your focus to one component, or include most of the ideas in a unit that incorporates science and/or technology themes. People have different sensitivities and reactions to different foods e.g. amount of spices in foods, perception of sweetness. Introduction We are all different: Set up a circus of activities to demonstrate that students have differing sensitivities and responses to foods for example PCT, the weakest solution of sugar that can be identified and metabolism of asparagus. Possible teaching/assessment activities Develop a class database that demonstrates the range of class sensitivities and reactions to different foods. Develop a questionnaire that determines people’s differing responses to foods. A bioinformatics system draws on information (including biological information) from a wide range of sources. Introduce the scenario Class discussion about the scope of the problem: What types of allergies and food reactions they have encountered? How might they find out more information? What range of foods in the tuckshop may be affected? Identify a range of foods to study (for example milk products containing lactose, high sugar products, diabetic products, and products with Vitamin C fortification). Bioinformatics systems require organisation to enable retrieval of specialised Identification of the problem and group/class organisation Organise the class into groups of 5-6 students. Brainstorm the dimensions of the problem and develop ©2005-2009 The University of Waikato www.biotechlearn.org.nz The development of a brief that indicates the components of the bioinformatics database Home > Focus stories > Nutrigenomics > Food forensics information, for example the relationship between ingredients listed on a snack food package and the list of ingredients that are associated with a particular allergy. library and web searching techniques. Introduce the class to expert grouping where each member of the group joins a group to become the expert in this area and reports back to their home group (Home and Away) (for example some groups become expert in food-related conditions, others becomes expert in food testing). Developing expertise Bioinformatics involves the assemblage of a large amount of detailed information. For this section divide the class up into expert groups who each have responsibility for a particular component. Make sure that there is a coordinator who is responsible for assembling the material into a computer programme (for example Microsoft Excel). Accessing the Community of Practice Get advice from an IT consultant on the development of an appropriate information retrieval system. Consult with expert groups on the types of information that needs to be included. Consult with an IT expert in your school about setting up a database of the composition of foods sold in the tuckshop that could provide a template for each customer. Research components of selected foods Interview a dietician about the composition of a balanced diet, food-related conditions and a range of food tests. Consult with a health practitioner (Health programme, school nurse) on a range of food-related conditions that are relevant to children (e.g. lactose intolerance, gluten/wheat intolerance, calcium deficiency, diabetes) Research digestion and related digestive disorders located in the digestive system. Research questionnaire development and consult ethical issues about keeping information confidential Consider the impacts (health, lifestyle) of having a ©2005-2009 The University of Waikato www.biotechlearn.org.nz including food allergies and ingredients of foods on the tuck shop shelves). Home > Focus stories > Nutrigenomics > Food forensics particular food-related condition Interview a family member/friend/classmate with a foodrelated condition that has been studied, and report back. Plan of action Consider the data that needs to be collected (design brief). Develop a plan for collecting data and assembling the material suitable for organising into a database. Collect data. Consult and refine according to the brief. Testing the database Trial the database with a small number of students from another class Adapt the database and present it to a range of students for trialling at the tuckshop. Develop a presentation of the database that explains your pathway and decisions. A bioinformatics system enables individuals to access the databases to determine the types of foods that are suitable for a person with a particular food allergy. Presentation of model system to stakeholder group. Present the database system to the stakeholder group along with evaluative data. ©2005-2009 The University of Waikato www.biotechlearn.org.nz The database system allows a student with a particular allergy to access the database of ingredients of snack food available at the tuckshop.