Indian Journal of Basic and Applied Medical Research; September 2 014: Vol.-3, Issue- 4, P. 46-63 Epidemiology of healthcare acquired infection – An Indian perspective on surgical site infection and catheter related blood stream infection V Ramasubramanian1, Vivek Iyer2*, Sandeep Sewlikar3 and Anish Desai4 1 Sr Consultant Infectious Diseases, HIV & Tropical Medicine, Apollo hospitals, Chennai Adjunct Professor of Infectious Diseases & Consultant, Sri Ramachandra Medical College & Research Institute (DU). Adjunct Associate Professor of Infectious Diseases, University of Queensland. Adjunct Associate Professor of Infectious Diseases, MGR Medical University 2 Infection Prevention Specialist, Johnson and Johnson Limited, Mumbai 3 Manager 4 – Clinical Affairs, Johnson and Johnson Limited, Mumbai Director – Medical Affairs and Clinical Operations, Johnson and Johnson Limited, Mumbai * Corresponding Author: Dr. Vivek Iyer ; Email: dr_vivekiyer@yahoo.co.in Date of submission: 08 June 2014 ; Date of Publication: 15 September 2014 ABSTRACT Healthcare acquired infections or hospital acquired infections (HAIs) are amongst the most common complications of hospital care, leading to high morbidity and mortality. While WHO estimates about 7-12% HAI burden in hospitalized patients globally, the figures from India are alarming, with an incidence rate varying from 11% to 83% for different kinds of HAIs. The article reviews literature and data for HAIs from India, with particular focus on surgical site infections (SSIs) and catheter related blood stream infection (CRBSI). The profile of SSIs and CRBSIs in India with a relative context to the relevant global data has been discussed. Key words: Hospital acquired infection, Surgical site infection, Catheter related blood stream infection, pathogens