OSU Physiology and Cell Biology
Monthly Newsletter
February, 2012
This edition is covering the news of January, 2012, and announcing seminars and
calendar events for February, 2012.
Please email your news to treon.4@osu.edu by the end of each month.
Research Awards
Rafael-Fortney JA, Janssen PM. Investigation of a new treatment target for heart failure in muscular dystrophy.
Muscular Dystrophy Assn Inc, $19,038.00, 01-01-10/12-31-12.
Ziolo MT. Nitric oxide signaling in healthy and diseased cardiac myocytes. NIH-NHLBI, $104,166.00, 01-01-10/12-31-13.
Research Submissions
-
-
Janssen PM. A new regulator of muscle fibrosis and repair. Nationwide Children’s, $200,554.00, 12-01-12/11-30-17.
Radwanski P, Gyorke S. Mechanism of arrhythmia prevention by tetrodotoxin-selective Na+ channel blockade in a
genetic model of catecholaminergic polymorphic ventricular tachycardia (CPVT). Heart Rhythm Society, $42,128.00,
07-01-12/06-30-13.
Brunello L, Gyorke S. Synchronization of extrasystolic Ca2+ release and contraction in cardiac muscle harboring the
arrhythmogenic CASQ2 mutation R33Q. AHA Great Rivers, $89,000, 07-01-12/06-30-14.
Janssen PM. A new role for dystrophin in cardiac beta-adrenergic response. TRINCH, $25,768.00, 07-01-12/06-3014.
Tang L, Ziolo MT. A novel regulation of CAMKII function by neuronal nitric oxide synthase. AHA, $50,000.00, 07-0112/06-30-14.
Roof S, Ziolo MT. Neuronal nitric oxide synthases’s role in the beneficial effects of exercise. AHA, $50,000.00, 07-0112/06-30-14.
Janssen PM, Davis JP, Ziolo MT, Biesiadecki BJ, Beattie CE, Rafael-Fortney JA, Gyorke S. Reprogramming
cellular function by rewiring calcium/calmodulin signaling pathways. NIH, $6,829,922.00, 09-01-12/08-31-17.
Janssen PM. New anti-fibrotic drug treatment for DMD. TRINCH, $23,252.00, 08-01-12/07-31-13.
Nixon B, Biesiadecki BJ. Troponin Phosphorylation Crosstalk. AHA, $50,000.00, 07-01-12/06-30-14.
Rowland LA, Periasamy M. SLN-mediated heat generation is the primary mechanism in UCP1-independent
thermogenesis. AHA, $50,000.00, 07-01-12/06-30-14.
Milani Nejad N, Janssen PM. Regulation of cardiac cross-bridge cycling rate via length-dependent Post-translational
modifications in health and disease. AHA, $50,000.00, 07-01-12/06-30-14.
Radwanski P, Gyorke S. The role of tetrodotoxin-sensitive NA+ channels in catecholaminergic polymorphic
ventricular tachycardia (CPVT). AHA Great Rivers, $89,000.00, 07-01-12/06-30-14.
Kalyanasundaram A, Periasamy M. Role of RyR2 mediated calcium leak in diabetic cardiomyopathy. AHA,
$46,000.00, 07-01-12/06-30-13.
Sopariwala DH, Periasamy M. The molecular basis for skeletal muscle based non shivering thermogenesis. AHA
Great Rivers Affiliate, $50,000.00, 07-01-12/06-30-14.
Shaikh SA, Periasamy M. How does the SERCA-SLN interaction lead to uncoupling and heat production? AHA,
$50,000.00, 07-01-12/06-30-14.
1
-
Maurya SK, Periasamy M. Increased ubiquitination as a mechanism for cardiac and skeletal muscle dysfunction in
Type 2 diabetes. AHA Great Rivers, $91,000.00, 07-01-12/06-30-14.
Publications
Wheeler DG, Joseph ME, Mahamud SD, Aurand WL, Mohler PJ, Pompili VJ, Dwyer KM, Nottle MB, Harrison SJ, d'Apice
AJ, Robson SC, Cowan PJ, Gumina RJ. Transgenic swine: Expression of human CD39 protects against myocardial
injury Wheeler, CD39 reduces myocardial injury in swine. J Mol Cell Cardiol. 2012 Jan 12. [Epub ahead of print].
Lou Q, Fedorov VV. Shock-Induced Focal Arrhythmias: Not Driven by Calcium? Heart Rhythm. 2012;9(1):105-106.
Conferences and Presentations
Dr. Mark Ziolo presented “Don’t Just Say NO: NOS1 Signaling in Cardiac Myocytes” during Cardiology Grand Rounds at
Johns Hopkins University on January 11, 2012.
Zhaobin Xu, a Postdoctoral Research in Dr. Gumina’s DHLRI lab, will present his poster entitled “CD39 Expression
Modulates Ischemia Induced Diastolic Dysfunction” in a moderated poster session at the American College of Cardiology
61st Annual Scientific Session, Sunday, March 25, 2012.
U
February 12, 13, 14:
Department Seminars and Meetings
Academic Review Self Study Site Visit
Tentative Agenda for Monday, February 13
Feb. 13:
9:00-9:15
304 Hamilton Hall
9:15-9:45
304 Hamilton Hall
9:45-10:15
304 Hamilton Hall
10:15-10:30
304 Hamilton Hall
10:30-11:00
304 Hamilton Hall
11:00-11:30
304 Hamilton Hall
11:30-12:00
304 Hamilton Hall
12:00-1:00
304 Hamilton Hall
1:00-1:30
304 Hamilton Hall
1:30-2:00
304 Hamilton Hall
All Faculty and Staff – Overview and Introductions
Cardiovascular Research Faculty
Cellular Research Faculty
Break
Neuroscience Research
Teaching Faculty
Untenured Faculty
Lunch w/ Graduate Students
Research Scientists & Postdoctoral Researchers
PCB Staff: Mary and Carolyn
February 21, 2011, 12:00 p.m., 302 Hamilton Hall: Faculty Meeting w/ Dean Lockwood
2
UReminders to Faculty
 OSU:pro
is being used now for all University and College Faculty reporting. Please keep your
profile updated - https://pro.osu.edu/. All Promotion and Tenure, Annual, Teaching, Research, and
other reports are now developed from the system for College and University uses.
 Faculty appointments and the semester conversion
Do you have questions about how faculty pay schedules, leave policies, or service credit will operate under semesters?
These issues and more are addressed in a series of frequently asked questions about faculty appointments and the
semester switch.
 Center for Education and Scholarship February Training Courses
The College of Medicine’s Center for Education and Scholarship will host Lead.Serve.Inspire curriculum training courses
for faculty in teaching skills and technology resources as the new curriculum is implemented this year. Training courses
for February include:
 Feb. 1 – Competency Based Learning and Assessment, 7 a.m., 1059 Graves
 Feb. 10 – Using the Meiling Auditoriums, 7:30 a.m., 1024 Graves
 Feb. 14 – Simulation in Med Ed, noon, 1069 Graves
 Feb. 15 – Facilitating Small Group Learning, noon, 518A James
 Feb. 16 – Articulate Overview, 4 p.m., 1024 Graves
 Feb. 22 – Articulate Overview, 5 p.m., B120 Graves
 Feb. 27 – Carmen Quizzes, noon, 1059 Graves
 Feb. 27 – Team Based Learning, 5 p.m., 1059 Graves
Register online. Contact Karla Vick at 292-0018 with questions.
University Senate elections underway
The University Senate has launched a new round of elections for faculty senators. The nomination phase is currently open
and will continue until Friday (2/3); the ensuing election period will run Monday (2/6)-Wednesday (2/29). Results will be
announced on Thursday (3/1).
When elected, senators accept a three-year term of service. They join administrators and student representatives at the
meetings of the University Senate, presided over by President Gordon Gee, and attend the meetings of Faculty Council
(the faculty caucus of the Senate), which raises issues specific to faculty life on the campus. Senators are also asked to
serve on at least one of the 20 Senate committees. (See the University Senate website for a complete listing of
committees, their current membership, as well as a directory of current senators.) Contact: Jim Rathman or Tim Gerber
Read the onCampus article about the Senate elections: http://oncampus.osu.edu/2012/01/senate-elections/
Physiology and Cell Biology Faculty Committee Reports
U
Merit – Dr. Janssen
Teaching – Dr. Lucas
Appointment, Promotion & Tenure – Dr. Strauch
Faculty Council – Dr. Lucas/Dr. Janssen
Graduate Recruitment – Dr. Davis/Dr. Biesiadecki
Seminar – Dr. Davis
Space – Dr. Rall
U
U
U
U
U
3
Department News and Announcements
On January 26, 2012, Dr. Gee invited Dr. Fedorov, Dr.
Biesiadecki and Dr. Laura Schmitt, an Assistant Professor
of Physical Therapy, for lunch in his office. They are all
relatively new Assistant Professors at The Ohio State
University. They had an informal discussion regarding their
work, life at Ohio State and life in general.
News
Notification Emails Being Sent to OSU Email Addresses Only
Beginning Thursday (Jan. 19), all email notifications (e.g. approvals) from the PeopleSoft Financial system, eRequest,
and eTravel will be sent to a user’s OSU email account (name.#@osu.edu). This change affects only users who currently
receive emails from these systems to their OSUMC email account (firstname.lastname@osumc.edu). This change has no
impact on the HR/SIS PeopleSoft System at this time. It is highly recommended that Medical Center employees forward
their OSU emails to their Medical Center email address to ensure delivery of important and time sensitive emails. Go to
my.osu.edu, enter your information and select Change Email Delivery to set up email forwarding. Call the OSUMC Help
Desk at 293-3861 with questions.
News
25 0 U N IV E R S IT Y H A L L | 23 0 N . O V A L MA L L | C O LU MB U S , O H 43 2 10 - 1 36 6 | P H : ( 61 4 ) 2 47 - 74 1 3 |
WWW .GRADSCH.OSU.EDU
Candidacy paperwork MUST be submitted by Graduate School deadlines
There have been several instances recently where the Graduate School has not been notified two weeks in advance of an
upcoming candidacy exam. The Notification of Candidacy Exam forms MUST be submitted to the Graduate School at
least two weeks before the proposed oral examination date. This time frame is essential so that graduation services staff
can validate the exam committee and resolve any potential problems. Forms will not be accepted outside of the two-week
notice, and any exam that takes place without prior clearance from the Graduate School will be invalidated. Contact: Tim
Watson, 247-7292
4
Hayes Graduate Research Forum — Friday, February 24
The 26th annual Edward F. Hayes Graduate Research Forum is set for Friday, Feb. 24, in the Ohio Union. This event
showcases the high quality research conducted by graduate students across Ohio State, and it is co-sponsored by the
Council of Graduate Students, Office of Research, and the Graduate School. The abstract submission deadline has
passed, and graduate faculty are judging the abstracts for possible participation. Faculty are encouraged to volunteer to
serve as presentation judges on the day of the forum. To apply and volunteer Contact: Allen Cochran, vice president,
Council of Graduate Students.
Important Graduate School Deadlines
Applications to graduate for winter quarter 2012, doctoral and master’s: Friday, Jan. 13
Submission of master’s and doctoral examination report forms: Wednesday, Feb. 29
Submission of final approved theses and dissertations: Wednesday, March 7
OSU Environmental Health & Safety News
Institutional Animal Care and Use Committee newsletter
The latest edition of the Animal Care and Use Newsletter is now available at http://orrp.osu.edu/iacuc/. This issue reminds
researchers of the upcoming IACUC semi-annual inspections, provides FAQs regarding the online process of animal
ordering, and has additional news and updates regarding animal research and hazardous agents.
News
Events Thursday and Friday Kick Off Heart Month
-
Interactive Lecture on Heart Disease Prevention
Join Martha Gulati, MD, director of Ohio State’s Women’s Cardiovascular Health Program, Thursday (Feb. 2) from 3-4
p.m. in the Ross Heart Hospital Auditorium for an interactive lecture on heart disease prevention. There will be a “build
your own” parfait bar with various toppings for a healthy afternoon snack. Each parfait is $5, and all of the proceeds will go
to the American Heart Association. Contact Emily Kaeding with questions.
-
Wear Red Day Is Friday
Friday (Feb. 3) is National Wear Red Day in support of preventing heart disease. Ohio State staff and faculty are
encouraged to wear red all day. The “Go Red” Prize Patrol will be on the lookout for those wearing red and will hand out
gifts to those who are “caught.” Contact Emily Kaeding for more information.
ID Processing and Security Office to Move
On Feb. 17, ID Processing, along with the administrative offices within in the Department of Security, will move
temporarily to the fifth floor of Cramblett Medical Clinic. ID Processing will be in room 5013. This temporary move will
allow for construction on the concourse that will connect the new James Cancer Hospital and Critical Care Tower to
Rhodes Hall. ID Processing will maintain normal hours at this temporary location. The Control Center for Security will
remain in its current location on the first floor of Rhodes Hall. ID Processing and the Security administrative offices will
remain in their new space until July.
Wednesday Lunch and Learn Session for Pelotonia Fellowship Program
The Pelotonia Fellowship Program is accepting applications for undergraduate, graduate, medical and postdoctoral
fellowships. A lunch and learn session about the program and application process will be held Wednesday (Feb. 1) at
11:30 a.m. in 105 Biomedical Research Tower. Register online. These fellowships are for cancer-related projects and can
go to students in any field of study. All students, who would like to conduct cancer research, are encouraged to apply. To
date, 116 fellowships have been awarded to students in various fields of study, including Arts and Sciences, Business,
Engineering, Humanities, Medicine and Pharmacy. This year, the program expects to fund an additional 49 fellowships.
Applications are due March 1. More information, including eligibility guidelines and an application, are online. Email Jeff
Mason with questions.
5
Receive Buckeye Alerts by Providing Cell Phone Number
The Buckeye Alert System is used to alert students and staff of any significant issue requiring action or of immediate
concern affecting the OSU and/or OSUMC campus. To sign up, staff must enter their cell telephone number at Employee
Self Service. There is not a special call out for Buckeye Alert but if a staff member has entered a cell phone number, they
are automatically signed up to receive Buckeye Alerts. The cell phone does not need to be listed as the preferred number,
it just needs to be entered. Contact Michael Gregory, director of Safety, for more information at 293-6738.
Making Posters in PowerPoint Class Offered Wednesday
Medical Visuals, a service of the Health Sciences Library, is offering free instruction on laying out posters using
PowerPoint. Email Meg Birmingham with questions and to preregister. Space is limited and walk-ins will not be accepted.
All classes will be held in 200 Prior Hall. Classes are: Wednesday (Jan. 18), 10-11:30 a.m.; Jan. 23, 2-3:30 p.m.; and
Feb. 9, 9:30-11 a.m.
Save the Date for 2012 OSUMC Research Day
Mark your calendars for the 11th Annual OSUMC Trainee Research Day, scheduled for April 18-19 at the Biomedical
Research Tower. Trainee Research Day provides faculty, staff and students an opportunity to learn about the biomedical
research conducted by trainees in the College of Medicine. This group spans the educational continuum of research
training from postdoctoral fellows and researchers, to medical and undergraduate students. Read more. Note to trainees:
Abstracts are due by Feb. 10.
Office of Research
Office of Sponsored Programs
(Formerly the Research Foundation)
News
Research Development and Grant Writing Newsletter
The January 2012 issue of Research Development & Grant Writing News is now available.
Some of the topics for this month include:
- NSF Math/Science Partnership Webinar Report
- Writing a Successful Project Management Plan
- Writing Shared Use Infrastructure Grants
- NIH Changes: NCRR Dissolved, NCATS Created
- New Funding Opportunities
- etc.
Next ARC Meeting - Register Today!
Join us on Tuesday (2/21/12), 9:30 a.m. - 11:00 a.m. in 1080 Physics Research Building and be sure to arrive early
(between 9:10 am - 9:30 a.m.) to enjoy refreshments and time for networking courtesy of the ARC Steering Committee.
Our agenda includes presentations from:
- Bernadette Melnyk, Associate Vice President for Health Promotion, Chief Wellness Officer, and Dean, College of
Nursing: Building Successful Programs of Funded Research in Health and Wellness
- Vedavyas (Vedu) Hariths, Research In View (formerly OSU:pro), Office of the CIO: Research In View goes live
on February 24th - Vedu will provide a system demo and overview
- Anne Moffat, Executive Director, Office of Sponsored Programs: Updates on semester conversion, salary caps,
and other research administration topics
- Other announcements.
UPCOMING RESEARCH TRAINING AND EVENTS - HTTP://OSP.OSU.EDU/TRAINING/
Pelotonia Fellowship Program - Lunch & Learn
02/01/2012 Register
NCURA TV – International Collaborations: Negotiations and Compliance 02/08/2012 Register
Exempt Forms Help
02/15/2012 Register
Administrative Research Council (ARC) Meeting
02/21/2012 Register
ARC Discussions – Access the Power of the PI Portal
02/23/2012 Register
Cost Sharing on Sponsored Programs
02/24/2012 Register
Grant Writing: An Introduction
02/29/2012 Register
6
OSP Job Aids/Training Guides
Being a PI at OSU – Roles and Responsibilities
Cayuse424
Effort Certification: What is it and why is it important?
Entrepreneurial Faculty: Advancing Innovation in a University Setting
Facilities and Administrative (Indirect) Costs at The Ohio State University
PI Portal
Required Research Personnel Training: http://researchonline.osu.edu/training/
INFO to KNOW for GRANT SUBMISSIONS
OSURF Benefit Rates
Appointment
Faculty 9 and 12 mo
Faculty (QOD)
A&P, including Post-Doctoral Researchers
CCS
Non-OSU Students, Visiting Scholars
GRAs, Pre & Post Fellows/Trainees, Students
FY12
28%
14.6%
36.7%
46.5%
14.6%
4.4%
F & A Rate
52.5%
2010 NIH Salary Cap
$179,700
"Thirty days hath September,
April, June, and November,
February has twenty-eight alone,
All the rest have thirty-one;
Excepting leap year, that 's the time
When February's days are twenty-nine."
-
traditional English mnemonic rhyme
 Happy Valentine’s Day! 
7
Conference Room Calendar – 304 Hamilton Hall
– subject to frequent changes - contact Carolyn or Mary for updates
U
U
FEBRUARY 2012
Sun
Monday
Tuesday
Wednesday
Thursday
Friday
Sat
2
3
9:30-11:30Jhiang
12:00-2:00Cell Biol Group
2:00-3:00Jakeman
1
2
9:00-11:00Robinson
12:00-1:30Big 6 Lab Mtg
3:30-5:30602 Tutorial
3
4
5
6
9:00-10:00CV Jrnl Club
7
9:30-11:30Jhiang
12:00-2:00Cell Biology
8
9:00-10:00Janssen
9
12:00-1:30Jakeman
10
2:00-4:00Periasamy
11
12
13
7:00-5:00 –
Academic
Review Site Visit
14
7:00-5:00 –
Academic
Review Site Visit
15
16
9:00-11:00Robinson
12:00-1:30Big 6 Lab Mtg
17
3:30-5:30602 Tutorial
18
19
20
9:00-10:00CV Jrnl Club
10:00-1:00 –
Haizlip Practice
21
9:30-11:30Jhiang
12:00-1:30Faculty Mtg
22
9:00-10:00Janssen
10:00-12:00Haizlip Defense
23
12:00-1:30Jakeman
24
2:00-4:00Periasamy
25
26
27
28
9:30-11:30Jhiang
29
8:00-2:00Roman Defense
8