Pilot Grants in Nanoparticle Magnetic Hyperthermia Treatment of Tumors
With funding provided by the National Cancer Institute especially for this purpose, the
Dartmouth Center for Cancer Nanotechnology Excellence (DCCNE) will fund pilot projects that
advance cancer investigations related to magnetic hyperthermia treatment of tumors. The
purpose of pilot grants is to support preliminary studies that demonstrate novel approaches and
provide preliminary data necessary for future grant applications. Possible areas of funding
include; development of novel magnetic nanoparticles or coatings for nanoparticles; novel
imaging techniques for magnetic nanoparticles; novel local non-invasive temperature
measurement techniques applicable to magnetic hyperthermia applications; and novel application
of magnetic nanoparticles for therapeutic purposes
Eligibility Criteria: The funding is available to any member of Dartmouth College, including
Geisel School of Medicine. Work may involve outside faculty as co-investigators. Investigators
currently funded by DCCNE are eligible to apply, but the application should address how the
request represents novel work in light of work currently funded by the DCCNE. Clinical studies
are not eligible for funding.
Review Criteria: Proposals will receive internal peer review. Criteria include scientific merit,
potential for eventual clinical application, and the likelihood of generating pilot data necessary
for a future grant application. Applicants should address the feasibility of the work proposed.
Preference will be given to pilot projects testing novel approaches to innovative and high-risk
aims. While not a pre-requisite to apply, involvement of co-investigators when more than one
research perspective is relevant is encouraged.
Awards: Funding for this announcement totals $55,000 in direct costs. Awards are planned for
August 1st start dates. Past Grantees may be allowed to compete for a second year of funding
based on a comprehensive review of progress in the first year. Given the pilot intent of the
awards, projects requiring principal investigators’ salary support and/or equipment purchases
should cite an institutional commitment to pursuing the results of the proposed work.
Applications: The application must include (1) biographical sketches for the principal
investigator and key personnel; (2) an abstract (250-word maximum); (3) a description of the
research proposed which is limited to four pages and must address background, aims, methods,
and cancer relevance. Applications should be submitted as a single PDF file to: Robert
Gerlach, NCCC Research Administrator by June 2nd.
Requirements of Awardees: Upon conclusion of the funding period, awardees are required to
submit an accounting of funds granted, together with a brief report of research results including
any resulting publications or presentations.
Questions regarding this announcement and applications should be addressed to:
Robert W. Gerlach, MPA, NCCC Associate Director for Administration and Scientific Affairs
Rubin 805
(603) 653-6187
Robert.W.Gerlach@Dartmouth.edu
Application for DCCNE Pilot Grants in Magnetic Hyperthermia
Face Page
Principal Investigator:
First Name, Last Name, Degree(s) ________________________________________
e-mail address: _______________________________________________________
telephone: ____________________________
Project Title: __________________________________________________________
__________________________________________________________
Abstract: (250-word maximum)
Description of Research Proposed: (4-page maximum)
1: Background: brief statement of ideas and reasoning behind the research project.
2: Specific Aims: objectives addressed by the project.
3: Methods: approach and feasibility.
4: Relevance of results to Magnetic Hyperthermia Treatment of Cancer.
Biographical Information: NIH Format (PHS 398) for each Principal Investigator
(4-page maximum)
Budget: NIH Form Pages 4 and 5 (including Budget Justification on Form Page 5)