Unit: Heredity (written November 2013) Key Learning: Cells need to grow and reproduce. As they do so, information needs to be passed down to the new cell(s). Our understanding of this process can be used to predict the characteristics of the new cells. Instructional Tools: Unit Essential Question: How do cells grow and divide? How are the characteristics of life passed down from one generation to the next? How can scientists predict and/or observe patterns in heredity? How does the information in DNA end up giving us our traits? How can our knowledge of genetics impact society? Concept: Concept: Mendelian genetics Probability and Inheritance 3.6.10.A, 3.1.10.C, 3.1.10.B, 3.3.10.C, Bio.B.2.1.1, Bio.B.2.1.2 3.3.10.C, 3.1.10.C, 3.1.10.B, Bio.B.2.1.1 Lesson EQ: What did Mendel discover about the patterns of inheritance? (A) Lesson EQ: How do different patterns of inheritance result in different phenotypic ratios? (A) What are various patterns of inheritance? (A) Concept: DNA Structure and Replication 3.3.10.B, 3.3.10.A, 3.1.10.B, 3.3.10.C, 3.1.10.C, 3.6.10.A, Bio.B.1.2.1, Bio.B.2.2.1, Bio.B.2.2.2 Lesson EQ: How does the structure of DNA account for how its stores and accurately copies its genetic information? (A) How are punnett squares used to predict the outcome of a cross? (A) Vocabulary: genotype, phenotype, inheritance, dominant inheritance, recessive inheritance, homozygous, heterozygous, hybrid, gene, allele, independent assortment, segregation, Punnett square, purebred, genetics, trait Vocabulary: co dominance, incomplete dominance, complete dominance, polygenic, multiple alleles, sex-linked, probability Vocabulary: DNA, DNA (semiconservative) replication, nucleotide, double helix, base pairing, chromatin, histone, DNA polymerase Concept: Concept: Concept: Protein Synthesis Genetic Engineering Meiosis 33.10.B, 3.3.10.C, 3.1.10.B, 3.1.10.C, 3..10.A, Bio.B.2.1.2, Bio.B.2.3.1 3.6.10.A, Bio.B.2.4.1 3.7.10.B, 3.3.10.C, 3.1.10.B, 3.7.10.A, Bio.B.1.1.1, Bio.B.1.1.2 Lesson EQ: How is genetic information used to code for the expression of traits? (A) What happens when this information is not copied correctly? (A) Lesson EQ: How is DNA evidence used in court cases? (A) How can new advances in genetics help to improve our lives? (A) Lesson EQ: How do cells create gametes that are haploid from an original diploid cell? (A) How does meiosis differ from mitosis? (A) What are the potential dangers of biotechnology? (A) Vocabulary: translation, transcription, mRNA, tRNA, anticodon, amino acid, protein, rRNA, codon, protein synthesis, intron, exon, RNA polymerase, gene expression, gene mutation, chromosomal mutation, inversion, point mutation, frameshift mutation, nondisjunction, duplication, translocation, deletion, polyploidy, differentiation Vocabulary: genetic engineering, hybridization, inbreeding, polyploidy, gel electrophoresis, Polymerase Chain Reaction (PCR), DNA profiling, plasmid, gene therapy, genetically modified food, selective breeding, gene splicing, genetic marker, forensics, , transgenic, biotechnology, recombinant organism, human genome project, cloning, genetically modified organism (GMO) Concept: Concept: Human Genetics Cell Growth and Division Bio.B.2.4.1, Bio.B.2.1.1 Bio B.1.1.1 Lesson EQ: How do geneticists and doctors study human inheritance? (A) Vocabulary: pedigree, karyotype, nondisjunction, carrier, autosome Lesson EQ: What events occur during the cell cycle? (A) Vocabulary: Chromatid, centromere, interphase, cell cycle, mitosis, prophase, centriole, spindle, metaphase, anaphase, telophase, cytokinesis, cyclin Vocabulary: meiosis, haploid, diploid, crossing-over, gamete, somatic cells, homologous, interphase…, nuclear division, cytokinesis, tetrad Additional Information: Models, internet simulations, practice worksheets, laboratory activities Vocabulary Report genotype – inheritance— dominant inheritance – genetics – trait – probability -DNA – Double helix – Base pairing – Chromatin— Histone – DNA polymerase -genetic engineering meiosis co dominance DNA profiling DNA (semiconservative) replication phenotype autosome incomplete dominance pedigree plasmid karyotype complete dominance mRNA gene therapy nucleotide tRNA haploid polygenic recessive inheritancemutation – gene mutation – chromosomal mutation – inversion – frameshift mutation – nondisjunction – duplication – translocation – deletion – polyploidy – differentiation -point mutation -genetically modified food diploid anticodon homozygous multiple alleles non-disjunction heterozygous selective breeding - carrier amino acid sex-linked hybrid protein – translation – transcription – intron -exon – RNA polymerase – Gene expression -biotechnology rRNA gene recombinant organism crossing-over codon allele gametes – somatic cells – homologous – nuclear division -protein synthesis – hybridization – inbreeding – polyploidy – gel electrophoresis – Polymerase Chain Reaction (PCR) – Gene splicing – Genetic marker – Forensics – Transgenic – Cloning – Genetically Modified Organism (GMO) -somatic cells independent assortment human genome project segregation homologous Punnett square purebred – chromatid – centromere – interphase – cell cycle – mitosis – prophase – centriole -spindle – metaphase – anaphase – telophase – cytokinesis – tetrad –