Brian W Dymock
Office Mailing Address: Department of Pharmacy, Faculty of Science, 18 Science Drive 4, Singapore
117543
Email:
phadbw@nus.edu.sg
Telephone:
6601 2495
Fax:
6779 1554
CURRENT POSITION (from July 2012)
Associate Professor, NUS Dept of Pharmacy
ACADEMIC QUALIFICATIONS
1994
BSc (1st), University of Strathclyde
1998
PhD, University of Glasgow
PROFESSIONAL QUALIFICATIONS
2001
Full Membership of the Royal Society of Chemistry (MRSC), UK (joined 1992)
2001
Chartered Chemist (CChem), Royal Society of Chemistry, UK
2006
Membership of the American Chemical Society, USA
EMPLOYMENT HISTORY
2011-2012:
Visiting Associate Professor, Dept of Pharmacy, National University of Singapore
2006-2011:
Head, Chemistry, S*BIO Pte Ltd., Singapore
2004-2006:
Department Manager, Discovery Chemistry, Evotec, UK
2001-2004:
Medicinal Chemistry Team Leader, Vernalis, Cambridge, UK
1997-2001:
Medicinal Chemistry Team Leader, Roche Discovery, Hertfordshire, UK
RESEARCH INTERESTS
Throughout my 15 year industrial career I have worked on a wide variety of medicinal chemistry and drug
development projects across a spectrum of industry. Key skills include: discovery of leads and
development of them into clinical candidates using organic synthesis, analytical chemistry, structurebased design (use of X-ray structures and computational chemistry to progress lead candidates), analysis
of multi-disciplinary structure activity relationships (SAR), progression of compounds through hit to lead
and lead optimization, pre-clinical development, CMC management for GMP material for clinical trials,
CMC regulatory and quality issues. Intellectual property – extensive experience of patent drafting for
composition of matter, use and solid form patents.
PUBLICATIONS / PATENTS / SCIENTIFIC AWARDS
 About 40 peer reviewed journal publications in chemistry and drug discovery
 Hold 19 patents in drug design and development areas.
 Most cited paper award, Bioorg Med Chem Lett, 2003-2006