2014 ICAA Annual meeting
www.icaahq.org
2014 ICAA Annual Symposium
October 10, 2014, New Orleans
Place: Tulane auditorium (First Floor)
Tulane University School of Medicine
1555 Poydras Street
New Orleans, LA 70112
Time: October 10, 2014
9:30-11:30 ICAA Board Meeting
ICAA welcome you to this international academic event. We hope that you enjoy the program and
wish you a happy stay in New Orleans.
ICAA president: Zhongcong Xie, MD, PhD
ICAA Secretary General: Hong Liu, MD, PhD
Local Host: Henry Liu, MD, PhD
1
2014 ICAA Annual meeting
www.icaahq.org
12:15-12:45 Open Ceremony and Greeting
Host/moderator: Hong Liu (SG of ICAA)
Dr. Zhongcong Xie (President of ICAA)
Dr. Jane Fitch (President of ASA)
Dr. Jin Liu (President of CSA)
Dr. Marc Kahn (Senior Associate Dean of Tulane Medical School),
Dr. Frank Rosinia (Chair of Anesthesiology Tulane)
Dr. Henry Liu (Associate Professor of Tulane)
Dr. Yang Sue (Chinese Society of Intergrative Anesthesiology)
12:45~14:30 Panel presentation “Clinical Study on Anesthesia”
We are honored to have Prof. Daniel I. Sessler give the keynote presentation on Advanced
Clinical Trial Methodology. Prof. Sessler is the Michael Cudahy Chair of the Department of OUTCOMES
RESEARCH at the Cleveland Clinic. He is also Director of the Outcomes Research Consortium: the
Consortium is the world’s largest clinical anesthesia research group and publishes a full paper every
5 days. He is an editor for Anesthesiology and serves as a reviewer for more than 50 journals. Dr.
Sessler has published more than 550 full research papers, including a dozen in the New England
Journal of Medicine and Lancet, which have been cited more than 20,000 times. His awards include a
Fulbright Fellowship and the ASA Excellence in Research prize.
Clinical Research Design
Daniel I. Sessler, MD
Michael Cudahy Professor and Chair
Department of OUTCOMES RESEARCH
Cleveland Clinic
9500 Euclid Ave — P77
Cleveland, OH 44195
DS@OR.org
Clinical research is potentially subject to five classes of error: chance, selection bias,
confounding, measurement bias, and reverse causation. The extent to which each degrades results is
a strong function of research design. The best protection is provided by randomization which prevents
selection bias and confounding, and by blinding which reduces measurement bias. Appropriately
randomized and blinded trials are thus considered to provide the highest level of evidence.
Parallel-group trials are by far the most common type of clinical trial. Cross-over designs allow
treatment effects to be reliably identified with far fewer subjects. However, cross-over designs are
only reliable for stable disease states and for time-limited treatments. Those restrictions preclude
using the design for “hard” outcomes such as stroke, infarction, cancer recurrence, and death. An
attractive design that is becoming more common is a factorial approach that allows investigators to
test two or more interventions simultaneously. Not only is the approach efficient, but it permits
evaluation of interactions among interventions that would be impossible in sequential trials.
Increasingly investigators recognize that the results of small trials are “fragile” (not necessary correct)
and that small studies typically over-estimate treatment effect. There is thus a trend to power studies
better’ that is, not just for statistical significance, but to provide reliable estimates of treatment effect.
2
2014 ICAA Annual meeting
www.icaahq.org
Moderator-Zhiyi Zuo, MD, PhD (immediate-Past president of ICAA)
Buwei Yu, MD, PhD (immediate-Past president of CSA)
1. Dr. Daniel Sessler (Cleveland Clinic)-“Advanced Clinical Trial Methodology”
2. Dr. Jeffrey H. Silverstein (Mount Sinai)-“What’s wrong with POCD”
3. Dr. Jin Liu (CSA president,)-“Perioperative Red Blood Cell Transfusion: from liberal to
restrictive, and finally to individualized”)
4. Dr. Hong Liu (UC Davis)-“ Does the incidence of postoperative acute kidney injury and
transfusion of blood products increased after synthetic colloid administration during
cardiac surgery?”
14:30~14:45 Break
14:45~17:20 Scientific Abstracts Presentation and Award Competition
Moderators: Jianzhong Sun, MD; Lingzhong Meng, MD (1st half)
1. New Concepts in the Airway Management (Huafeng Wei, MD, PhD)
2. Influence of obstructive jaundice on pharmacodynamics and blood concentration of rocuronium (Zhenmeng Wang, MD, PhD.)
3. Anesthesia Machine Workshop: What did we learn? (Lingqun Hu, MD)
4. Analysis of 516 cases of gastrointestinal endoscopy and comfortable Medical Association survey (He Liu)
5. The anti-inflammatory effect of propofol in asthmatic airway is mediated by inhibiting Th2 cell
differentiation via GABAA receptor (Jingxia Meng, M.D.)
6. Critical role of P2X7 receptor in the neuroinflammation and cognitive dysfunction after surgery (Bin Zheng)
7. Sevoflurane may promote invasion and inhibit migration of glioma cells (Renchun Lai, MD)
8. Intranasal salvinorin A reduces cerebral ischemia/reperfusion injury in mouse middle cerebral artery
occlusion model (Chunhua Chen)
3
2014 ICAA Annual meeting
www.icaahq.org
Moderators: Jing Zhao, MD, (2nd half), Chuanyao Tong, MD
9. δ-opioid receptor agonist attenuates post-resuscitation brain injury in a rat model of asphyxial cardiac
arrest (Lu Yang)
10. µ opioid receptor-dependent activation of spinal mTOR during chronic morphine exposure (Linlin Sun,
PhD)
11. Inhibiting spinal mTOR attenuates the development and maintenance of morphine-induced tolerance and
hyperalgesia (Lingli Liang, MD, PhD)
12. Degenerated Central Cholinergic neurons injured by surgery paly a pivotal role in postoperative cognitive
dysfunction (Huan Xu, MD)
13. Cyn-1 regulates anesthesia toxicity but not anesthesia action in Caenorhabditis elegans (Cheng Ni)
14. Anesthetic sevoflurane induces cognitive impairment in young mice through Tau phosphorylation (Jie
Zhang)
15. Dexmedetomidine Attenuates Neurotoxicity Induced by Prenatal Propofol Exposure in Rats (J. Reyes and
M. Xiong)
16. Perioperative Dexmedetomidine does not Improve Long Term Outcomes in Chinese Cardiac Surgery
17:20-17:30: Tuoren Medical speaker (Platinum LEVEL SPONSOR)
17:30~17:50 Award presentation
Moderator: Renyu Liu MD, PhD (Vice President of ICAA), Chuanyao MD (president-elect of ICAA)
17:50 Closing Remarks
Zhongcong Xie, MD, PhD (President of ICAA)
4
2014 ICAA Annual meeting
www.icaahq.org
18:00: Departure to the dinner party
FIVE HAPPINESS
3605 S Carrollton Ave
New Orleans, LA 70118
504-482-3935
Dinner party coordinators: Yun Xia, Lingqun Hu, Shaofeng Zhou, Henry Liu, etc…..
Contact person in New Orleans:
Dr. Henry Liu (504-813-4983)
Direction from Convention center to the meeting place
5
2014 ICAA Annual meeting
www.icaahq.org
Acknowledgment
ICAA appreciates the Tulane University and the Department of Anesthesiology for their
outstanding effort hosting this symposium
ICAA appreciates the sponsorship from the following third parties for their nonrestrictive
support for this symposium
http://www.tuoren.com/html/en/
http://www.mindray.com/en/aboutus/aboutus.html
http://www.fresenius-kabi.com/
http://www.uescope.com/
http://www.healthcare.philips.com/cn_zh/
http://www.nhwa-group.com/enhuaEnglish/channels/109.html
*************************
Contact Dr. Jianzhong Sun (jzsun2001@yahoo.com), the treasurer of ICAA, to join
ICAA!
ICAA appreciates your strong support and participation!
6