Name: _________________________________ Study Guide: Chapters 12 and 13 Mendelian Genetics & DNA and RNA Intro Hybrid Homozygous Phenotype Character Dominant mRNA Trait Recessive tRNA Cross P generation rRNA Gene F1 generation RNA Allele F2 generation DNA Heterozygous Genotype DNA polymerase 1. What was Mendel’s educational background and why did this allow him to be so successful in his heredity experiments? 2. What organism did Mendel do his experiments with? 3. Give three reasons why this model organism was very good for genetic experiments? 4. What is the definition of ‘genotype’? 5. What is the definition of ‘phenotype’? Page 1 of 6 Name: _________________________________ 6. How many PAIRS of chromosomes do humans have? 7. Why do we see some genetic conditions show up in males much more than they show up in females? 8. Describe the shape and size of human sex chromosomes: 9. What does DNA look like in its most condensed form? 10. What does DNA look like in its least-condensed form? 11. Where is DNA contained within each cell type (prokaryotic vs. eukaryotic)? Why is this location especially important for eukaryotes? 12. What does DNA stand for? 13. What does RNA stand for? Page 2 of 6 Name: _________________________________ 14. Why did Mendel need ‘true breeding’ plants for his experiments? 15. Why is Mendel’s work so significant, considering the time period he was working in (1860’s)? 16. List and define each of Mendel’s three Laws of Inheritance: a. Law of ____________________________________: b. Law of ____________________________________: c. Law of ____________________________________: 17. What is the definition of ‘Codominance?’ Give one example of how this concept works. 18. What is ‘Incomplete Dominance?’ Give one example of how this concept works. 19. Define ‘polygenic’ and give an example of a polygenic trait. Page 3 of 6 Name: _________________________________ 20. Define ‘sex-linked traits.’ 21. What three terms do we use to characterize the GENOTYPE of an individual? 22. Name the four nucleotides found in DNA. How do you know which nucleotides bond to each other? 23. What are the three major components of every nucleic acid? 24. What does DNA physically look like? 25. What does RNA physical look like? 26. During what phase of the CELL LIFE CYCLE is the entire genetic code copied? Why do we need two copies of all the DNA instructions? 27. What is a monohybrid cross? 28. What is a dihybrid cross? Page 4 of 6 Name: _________________________________ 29. Explain the major differences between prokaryotic and eukaryotic DNA: 30. List the three types of RNA we discussed in class and describe the job of each type. 31. Why is the final goal of biology often to produce PROTEINS? Why are proteins so special and so important?? 32. Why is DNA replication described as ‘semi-conservative?’ What does this mean and why is this beneficial to us? Fill in the blank: 33. ________________________________________ is known as the father of modern genetics. 34. A _________________________________ is the result of mixing two genetically different parents. 35. If we cross two individuals to examine a single genetic trait, we have performed a _______________________ cross. 36. If an individual has two different alleles for a given gene, that individual is described as ________________________________. 37. ____________________ is the type of RNA that decodes mRNA and translates it into a protein. 38. DNA replication is characterized as being _______________________________________. Page 5 of 6 Name: _________________________________ 39. The process of duplicating a cell’s entire genetic code occurs during _______ phase of the cell life cycle. 40. Each gene serves as a recipe for constructing a ____________________________. 41. Mendel found that when crossing two ‘true-breeding’ individuals, the F1 offspring show _______________________ phenotypes. 42. ________________________ are two different version of the same gene. 43. If an individual has two of the same alleles for a given gene, that individual is described as ___________________________. 44. _____________________________ are the organelles responsible for protein synthesis. 45. The allele that is always exhibited when it is present is known as the ______________________ allele. 46. In eukaryotic cells, protein synthesis takes place in the _____________________________. 47. The type of RNA responsible for transporting the RNA message from the nucleus to the ribosome is called ____________________. Page 6 of 6