King Saud University
College of Pharmacy
Department of Pharmaceutics
Sterile Preparations
434 PHT
I -Group activity fileSupervised by ; Dr. Omaimah Jawharey
Done by:
Bashayer Al-Shehrey
Ala'a Al- Balawi
Sarah Al-Osaimi
Norah Al-Khudayr
Arwa Al-Essa
Aiah Hassanein
Al-Jawharah Al- Aishe
Reem Al-Saq'abi
Malak Al-Owais
Sarah Al-Mesnad
‫بسم هللا الرحمن الرحيم‬
Q. Match Column A with Column B appropriately :
Column A
1- It used to replace body fluids lost from the
circulation.
2- second to the IV route in rapidity onset of systemic
action.
3- the volume injected is 2 ml or less.
4- the volume injected varies from 1 ml or less to 500ml
or even more.
5- administrated between the inner layer (dermis) and
the outer layer (epidermis).
6- the volume injected less than 20 ml into particular
areas of spinal column.
7- it used to improve the circulation to the extremities
when arterial flow is restricted by arterial spasms.
8- stimulant following cardiac arrest.
9- local administration of anti inflammatory agents .
10- easily liberate the active drug in the body.
Matching
(A)
Column B
A- Large volume parenterals (LVP)
(B)
B- intramuscular route
(C)
(D)
C- S.Q injection
D- I.V injection
(E)
E- I.D injection
(F)
F- Intraspinal injection
(G)
G- intra- arterial injection
(H)
(I)
(J)
H- intracardial injection
I- intra articular injection
J- Prodrug.
Q. Sign the Following Statement with T or F:
1-The volume of I'm injections are rarely greater than 2ml and should not exceed 4 ml at one site (T)
2-IM route is the only site to be used for suspension and oily solutions. (T)
3-the volume injected SQ is 2ml or less (T)
4-drugs given by SQ route will have a slower onset of action than by I'm and IN routes (T)
5-the volume injected by IV route varies from 1ml or less , to 500 ml or even more (T)
6-intradermal injections are made onto the skin between the inner layer (dermis) and the outer layer
(epidermis) . (T)
7- The volume that can be injected intradermally is necessarily small, usually 0.1-0.2 ml. (T)
8-intraspinal injections are injected in volumes less than 20ml into particular areas of the spinal column.(T)
9-intradermal route is use mainly diagnostic purposes in investigations of allergy. (T)
10-intra-arterial injections to improve circulation to the extremities in early gangrene. (T)
11-intra-cardiac injections are given in emergency only as a stimulant following cardiac arrest(T)
12-Intra-articular injections are administered as an aqueous solution or suspension into the synovial fluid in
a joint cavity.(T)
13- intra-articular injections are often used for the local administration of anti-inflammatory agents.(T)
Q. MCQ:
1)IM route of administration is second only to ....... In rapidity onset of action:
A-Intrathical route
B-Oral route
(C-)IV route
D-Intradermal route
2)The volum injected in S.Q. Or hypodermic:
(A-)2mL or less
B- 5mL or less
C-6mL or less
D-8mL or less
3)Only drugs in aqueous or hydroalcoholic solution are to be given by IN(intranasal)
(A-)True
B-False
4)Which route of the following can be used to replace body fluids lost from the circulation as a result of
severe burns,vomiting...etc:
A-Eye drops
(B)IV infusion, large volume parenterals(LVP)
C-Intranasal
D-All of the above
5- Parental product are a dossage form which are delivered to the patient by ............... Into body fluids,tissue
or organs.
A- Injections
B- Implantations
(C-) All the above
6- Parental therapy is used to:
A- Produce local effect.
B- Administer drugs if the oral route cannot be used.
C- Deliver the drug to the unconscious patient.
D- Rapidly correct fluid & electrolyte imbalance.
E- Ensure delivery of the drug to target tissues.
F- Ensure delivery of adequate concentration of the drug to disease or target area of the body.
I- A,B,E,F
II- A,C,D,F
III- Only A,B
(XI-) A, B, C, D, E, F
7- Intravenous, Intramuscular, Intradermal, Intraspinal, Intra-arterial, Intra-cardiac injections and Intraarticular injections all are routes of administrations.
(A-) True.
B- False.
8- All is true about Intravenous injection EXCEPT:
A- These are made into a vein , therefore are introduced directly into the blood stream.
B- The volume injected varies from 1 ml or less to 500 ml or even more.
(C-) Drugs are given by this route when a slow effect is required.
9- the intra-dermal injection is mainly used for:
(A) diagnostic purposes
B- treatment purposes
10- intra-arterial injections used for immediat effect in
Preipheral area:
A- to improve circulation in extremities
B- to minimize the S.E of the drug in order body tissues
C- to direct the drug to target organ
(D) all the above
11- intra-articular injection often used :
(A) locally
B- systemicaly
C-both
12- the physical and chemical stability of the product can be controlled by contorlling:
A-partical size
B-crystal form
C-humidity content
(D) all of the above