Job ID: 106496 PhD Student - Guide Cardiac Resynchronisation Siemens Healthcare | South England Siemens Healthcare have a new and exciting opportunity for a PhD studentship in a co-funded research project looking at Cardiac Resynchronization Therapy (CRT) in partnership with King’s College London and Guy’s & St. Thomas’ Hospitals NHS Foundation Trust, leading centres for clinical translational research.. Heart Failure (HF) is a leading cause of morbidity and mortality in the developed world. According to clinical studies, CRT is an efficient treatment for HF for 70% of the implanted patients. However, 30% of the remaining patients do not improve or even get worse. These non-responders are a strong burden to healthcare systems by causing considerable unnecessary costs. This project will develop, validate and test novel strategies for functional and anatomical ventricular characterization in order to stratify patients with HF. The approach will be based on multi-parameter characterization of ventricular motion, scar burden and distribution, electrical activity and anatomy using non-invasive measurements from medical imaging (primarily MRI) and body surface potential mapping. Dimensionality reduction will be carried out using manifold learning approaches and classification will be achieved using machine learning techniques What do I need to qualify for this job? As part of your PhD, you will be asked to Review literature Develop robust strategies for co-registration of functional and anatomical data Proven programming experience, preferably with C++ and Python. Strong knowledge of medical image processing and/or machine learning. Knowledge in statistics would be an asset. High level of motivation and positive thinking. You must be a high caliber graduate, ideally with some experience in a clinical environment. You will need strong communication and people skills with the confidence to present to groups of healthcare and industrial professionals at all levels. What else do I need to know? What are my responsibilities? Develop novel approaches for dimensionality reduction and stratification of patients based on machine learning Validate and test the developed approach in the clinical setting. This role will be a fixed term 3 year PhD studentship based at Kings College London; academic/tuition fees are included. There will be an element of European (Siemens HQ) and international travels.