Gas measurement REFIDs for partial pressure and concentration Paul Schluter May 8, 2013 Core Proposal 1. Specify two top-level vocabulary branches for gas concentration and partial pressure measurements: MDC_CONC_AWAY for measurements obtained at the patient airway and MDC_CONC_GASDLV for measurements obtained in the system supplying the gas to the patient, with or without a mechanical ventilator.1 The vocabulary branch REFID prefix is followed by the gas identifier and measurement phase on the waveform, similar to the terms already defined ISO/IEEE 11073-10101-2004. 2. For both MDC_CONC_AWAY and MDC_CONC_GASDLV, the gas measurement site may be specified in cases where greater semantic precision is required. These would be conveyed by OBX-20 in an HL7 V2.6 message. In each list, one of the enumerated values is identified as the ‘default’ value is OBX-20 is empty. 3. Since the expiratory _EXP and inspiratory _INSP breath phases are somewhat ambiguous, greater precision can be specified by an enumerated value that also has a specified default value. 4. The units-of-measure are conveyed by a separate attribute, e.g. OBX-6 in an HL7 V2.6 message. The table below lists the REFIDs for representing the concentration or partial pressure of desflurane. CF_CODE10 REFID 152024 152084 152112 152168 {152052} {152140} {152200} SysName Concentration | | MDC_CONC_AWAY_DESFL Desflurane, Gas | Airway Concentration | EndTidal | MDC_CONC_AWAY_DESFL_ET Desflurane, Gas | Airway Concentration | Expiration MDC_CONC_AWAY_DESFL_EXP | Desflurane, Gas | Airway Concentration | Inspiration MDC_CONC_AWAY_DESFL_INSP | Desflurane, Gas | Airway Concentration | | MDC_CONC_GASDLV_DESFL Desflurane, Gas | Gas Delivery System Concentration | Expiration MDC_CONC_GASDLV_DESFL_EXP | Desflurane, Gas | Gas Delivery System Concentration | Inspiration MDC_CONC_GASDLV_DESFL_INSP | Desflurane, Gas | Gas Delivery System CommonTerm Concentration airway desflurane Concentration airway desflurane end tidal Concentration airway desflurane expiratory Concentration airway desflurane inspiratory Concentration desflurane (gas delivery system) Concentration airway desflurane expiratory (gas delivery system) Concentration airway desflurane inspiratory (gas delivery system) Description Concentration of desflurane in airway gas Concentration of desflurane in airway gas measured at the end of expiration Concentration of desflurane in airway gas measured during expiration Concentration of desflurane in airway gas measured during inspiration Concentration of desflurane in airway gas in the system supplying the gas to the patient Concentration of desflurane in airway gas in the system supplying the gas to the patient during expiration Concentration of desflurane in airway gas in the system supplying the gas to the patient during inspiration Notes (informative) 1. The existing REFID prefix MDC_VENT_CONC has been changed to MDC_CONC_GASDLV on 5/8/2013 to indicate that the term refers to the system supplying the gas to the patient, regardless of whether a ventilator is used or not. This closely parallels the existing MDC_VENT_CONC, and, in fact, will be defined as a ‘REFID synonym’ that uses the same numeric code (CODE10 and CF_CODE10) as the corresponding MDC_VENT_CONC term, enclosed in {wavy braces}. The MDC_CONC_AWAY_ branch is already defined in ISO/IEEE 11073-10101-2004 and we’re simply re-using those terms. The MDC_CONC_GASDLV_ is new but closely parallels the existing MDC_VENT_CONC_ branch except that there is a strong expectation that the measurement site will be specified, e.g. in OBX-20 in an HL7 V2.6 message. 1 GasREFIDs.3a.docx -1- 2013-05-08T14 Notes (normative) 1. The REFID prefix MDC_CONC_AWAY_ denotes gas concentration and partial pressure measurements obtained at the patient airway (MDC_GAS_MSMT_SITE_AIRWAY) unless otherwise specified by an optional measurement location attribute, e.g. OBX-20 in an HL7 V2.6 message, using one of the following enumerated values listed below. MDC_GAS_MSMT_SITE_UNKNOWN MDC_GAS_MSMT_SITE_AIRWAY MDC_GAS_MSMT_SITE_YPIECE MDC_GAS_MSMT_SITE_ENDOTRCH … other breathing circuits::sites unknown airway adaptor (default) Y-piece Endotracheal 2. The REFID prefix MDC_CONC_GASDLV_ denotes gas concentration and partial pressure measurements in the system supplying the gas to the patient obtained at the fresh gas port (MDC_GAS_MSMT_SITE_FRESHGAS) unless otherwise specified by an optional measurement location attribute, e.g. OBX-20 in an HL7 V2.6 message, using one of the following enumerated MDC_GAS_MSMT_SITE_UNKNOWN MDC_GAS_MSMT_SITE_FRESHGAS MDC_GAS_MSMT_SITE_EXHAUST MDC_GAS_MSMT_SITE_INSP MDC_GAS_MSMT_SITE_EXP unknown fresh gas (default) exhaust inspiratory port expiratory port 3. The suffixes _INSP and _EXP denote the entire inspiratory and expiratory phase of a breath, respectively, and may be further qualified by an optional attribute that specifies the calculation method.2 MDC_METHOD_CALC_UNKNOWN MDC_METHOD_CALC_MAX MDC_METHOD_CALC_MIN MDC_METHOD_CALC_MEAN MDC_METHOD_CALC_MEAN_FLOW_WEIGHTED MDC_METHOD_CALC_MEDIAN not otherwise specified maximum minimum mean value, time-weighted mean value, flow weighted median value Questions raised during our Wednesday discussion: 1. In the current proposal, the MDC_CONC_GASDLV_ is defined as a ‘REFID synonym’ to the existing corresponding MDC_VENT_CONC_ terms, using the same numeric CODE10 and CF_CODE10. Should we assign new numeric codes for the MDC_CONC_GASDLV terms, at the cost of consuming the remaining few numeric codes currently left in the SCADA partition? 2. In the normative notes #1 and #2 above, the measurement site was left as ‘optional’ with a pre-defined default value defined in the standard. An alternative approach would be to make the measurement site location mandatory. Preferences? [If we decide on ‘optional’ with a pre-defined default value, the default value will be specified in the RTMMS.] 3. During our discussion on Wednesday, that case of where ‘no gas delivery’ occurs when intravenous anesthetics are used. What is the best way to specify that? 2 Most observation identifiers in the SCADA partition support the two-bit disrciminator for _MIN, _MAX and _MEAN. GasREFIDs.3a.docx -2- 2013-05-08T14 Gas Parameter Usage Exhaust Exp Fresh Gas Insp Ken Marks GE Healthcare October 12, 2009 Gas/Agent parameter measurement locations Fresh Gas Exhaust Insp Limb Exp Limb Y-Piece Endotracheal Alveolar Gas/Agent parameter measurement time spans & points Insp Phase Exp Phase End Tidal End Insp Breath Cycle Fresh Gas Ctrl Insp Ctrl Exp Ctrl End Tidal Ctrl Note: Titration mechanisms are dependent upon the capabilities of the gas delivery system. Purely pneumatic delivery systems are only capable of setting the fresh gas and cannot provide closed loop compensation due to the absence of sensing and electronic/electro-mechanical control. Electronic gas delivery systems (i.e. electronic mixers and vaporizers) are capable of all these mechanisms because they have the ability for remote control of gas settings via an electronic interface and can be controlled based on compensation from measurements. GasREFIDs.3a.docx Gas/Agent Delivered CH4 Ethanal CO end start flow conc dt end flow dt Note: Concentrations are measured as partial pressures. Accuracy is affected by barometric pressure, temperature, and humidity. NO2 NO He Ar N2 Isoflurane Air Enflurane CO2 Sevoflurane O2 Halothane M A C Gas B alance Gas M et ab o lically U sef ul M et ab o lically C o nsumed M et ab o lically Pr o d uced U nwant ed Gas start Consumption Production Xe Desflurane V o lat ile A g ent s conc dt Case Delivery Total Delivery Gas Physiological Parameters A g ent / Gasses end start conc flow N2O conctime Gas/Agent Parameter Calculations Mean - time wt - flow wt Min Max Gas/Agent parameter setting mechanisms -3- 2013-05-08T14