Chapter 12: Meiosis and Sexual Reproduction Introducing Alleles In ______________________________, a single individual gives rise to offspring that are identical to itself Asexual reproduction produces genetically ______________________________ In ________________________________________, two individuals mix their genetic material in the production of offspring ______________________________of sexually reproducing eukaryotes contain pairs of homologous chromosomes: One from the mother and one from the father ______________________________: carry genes (one from the mother and one from the father) of the same characteristics Different forms of the same gene are called____________________ ____________________: forms of a gene with slightly different DNA sequences; may encode slightly different version of the gene’s product Paired genes on homologous chromosomes may ____________________ ____________________as alleles arise by mutation and are the basis of differences in shared traits Offspring of sexual reproducers inherit ____________________of parental alleles resulting in new combinations of traits On the Advantages of Sexual Reproduction Sex ____________________________________________________________, so offspring have unique combinations of traits, this diversity offers a better chance of surviving environmental change than clones Meiosis Halves the Chromosome Number Sexual reproduction mixes up alleles from two parents and involves the fusion of two mature reproductive cells called ____________________ _________________ are specialized cells that are the basis of sexual reproduction ____________________ are derived from ______________________________: immature reproductive cells In males, the diploid germ cell develops into ____________________ In females, a diploid germ cell becomes an ____________________ All gametes are ____________________,their chromosome number is half of the ____________________number Human somatic cell (diploid) ____________________ Human gamete (haploid) ____________________ ____________________ is a nuclear division that halves the chromosome number in the reproductive cells, ensures that offspring have the same number of chromosomes as the parents Meiosis involves ________________________________________where a single diploid cell becomes four haploid cells: Prior to the cellular divisions ______________________________occurs First cellular division ____________________): instead of sister chromatids splitting and going to separate cells like in mitosis, _____________________ __________split and are packaged into separate cells In this cellular division __________cell forms __________cells Second cellular division (____________________):____________________ __________split and are packaged into separate cells In this cellular division _____________cells form __________cells Fertilization Restores the Chromosome Number Haploid gametes form by ____________________ The diploid chromosome number is restored at ____________________n when two haploid gametes fuse forming a ____________________ which is _________________ ____________________: cell formed by the fusion of two gametes If meiosis did not precede fertilization, the chromosome number would ______________ with every generation Chromosome number changes can have drastic consequences in animals Meiosis I Meiosis I: ____________________ Homologous chromosomes ____________________, ____________________, and ____________________ Spindle microtubules attach to ______________________________as the nuclear envelope breaks up Meiosis I: ____________________ The ______________________________pairs are aligned midway between spindle poles Meiosis I : ____________________ The ______________________________separate and begin heading toward the spindle poles Meiosis I: ____________________ Two clusters of ______________________________reach the spindle poles A new nuclear envelope forms around each cluster, so _________________ ____________________form Meiosis II Meiosis II: ____________________ The chromosomes ____________________ The ______________________________breaks up Spindle microtubules attach to each ______________________________ Meiosis II: ____________________ The (still duplicated) ______________________________are aligned midway between poles of the spindle Meiosis II: ____________________ All ______________________________separate The (now unduplicated) ____________________ head to the spindle poles Meiosis II: ____________________ A complete set of____________________clusters at each spindle pole A new ______________________________encloses each cluster __________ __________ (n) nuclei form Two events in meiosis introduce novel combinations of alleles into gametes: ____________________________________________________________ ____________________________________________________________ Along with fertilization, these events contribute to the ____________________ in combinations of traits among the offspring of sexually reproducing species Crossing Over in Prophase I During prophase I chromatids of homologous chromosomes ____________________ and align along their length and ______________________________ This exchanging of segments is called ______________________________and it introduces novel combinations of traits among offspring by creating new chromatids composed of a ________________________________________ In humans between 46 and 95 crossovers occur per meiosis, with an average of at least one crossover per chromosome Chromosome Segregation When homologous chromosomes separate in meiosis I, one of each chromosome pair goes to each of the two new nuclei For each chromosome pair, the maternal or paternal version is equally __________ ________________________________________ Human gametes have 23 pairs of homologous chromosomes Each time a human germ cell undergoes meiosis the four gametes that form end up with one of __________ __________ (or 223) possible combinations of homologous chromosomes ______________________________increases these combinations The chance that the maternal or paternal version of any chromosome will end up in a particular nucleus is 50 percent due to the way the spindle segregates the homologous chromosome during meiosis I