Syllabus - Genetics and Bioengineering

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NS 207 – ORGANIC CHEMISTRY
Full Course Title:
Organic Chemistry
Organska Hemija
Course Code:
NS207
Course Level/BiH cycle:
I cycle; 2ndyear
ECTS credit value:
6 ECTS
Student work-load:
For the whole semester (numbers are represented in hours)
Lectures
Tutorial /
Practical training/discussions
Individual
learning
TOTAL
40
10
50
100
Expected workload!
Length:
FALL 2015
Faculty/School/Department:
FENS, Genetics and Bioengineering
Course leader:
Jasmin Šutković
Contact details:
Office:
Office hours:
F3-24
Monday 14-16
Wednesday 14-16
Any time you find
me!
e-mail:
jsutkovic@ius.edu.ba
Phone:
+38733957187
Site:
IUS A building , A F2.13 for Monday lecture and A F1.11 for Wednesday lecture.
Host Study Program:
Genetic and Bioengineering
Course status:
Program course - required
Pre-requisites:
Chemistry
Access restrictions:
No
Assessment:
Lectures,Homework’s,Attendance, Quizzes, Project, Midterm exams and Final Exam
Date validated:
October, 2015
This course shall teach the students to acquire knowledge about the nature and its compositions.
In order to accomplish this, the following objectives will be achieved:

To build a basic knowledge of the structure of organic compounds

To understand the function of organic molecules in the cell.

Use of organic compounds in daily life

To analyse scientific concepts and think critically

To review the importance and relevance of chemistry in our everyday lives

To be able to utilize the methods of science as a logical means of problem solving
Course aims:
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Learning outcomes:
Indicative syllabus content:
Learning delivery:
Assessment Rationale:
Assessment Weighting:
Essential Reading:
Our goal is to teach the students the fundamental concepts of organic and biological chemistry
and in this way illustrate how chemistry explains many aspects of everyday life. Thekey feature is
the use of molecular art to illustrate and explain common phenomena we encounter every
day.Students will be given enough detail to understand basic concepts, such as how the natural
and synthetic organic compounds are synthesized and these compounds affect our daily life.
Introduction to organic chemistry, atoms and atomic theories, Chemical compounds and their
chemical reactions.How to Write a Formula for an Ionic Compounds and how to name a Covalent
Molecule. Alkanes, unsaturated organic compounds,Organic Compounds That Contain Oxygen,
Halogen, or Sulfur, aldehydes, ketones, chemistry of lipids. Carbohydrates, proteins and nucleic
acids.
Lectures and in class tutorials.
Assessment concept is based on continuous work with students during the semester. Evaluation
method is based on giving points for each activity, homework assignments, quizand midterm
examination during semester, as well as on final exam.
Quiz 2x
20%
Midterm exam
20%
Project
10%
Homework’s (5x)
Attendance
Final exam
10%
5%
Required , more than 70%
35%
Total
100%
Janice G. Smith, 2010. General, Organic, and Biological Chemistry, McGraw-Hill, ISBN 978-0-07302657-2
Bruice, P. K. 2010, Essential Organic Chemistry, Pearson ISBN 10:0-321-64416-6
Recommended readings:
Intranet web reference:
Important notes:
Check with the lecturer for more references.
Virtual book:https://www2.chemistry.msu.edu/faculty/reusch/virttxtjml/intro1.htm
Attendance policy:
Absence from lectures shall not exceed 30%. Students who exceed the limits with medical or
emergency excuse acceptable and approved by the Dean of the relevant faculty shall not be
allowed to take the final examination and shall receive a mark zero for this course
Course policy:
During examination (quiz, midterm and final exam) students are allowed to use calculators and
accessories approved by the course lecturer. MOBILE PHONESare strictly prohibited during the
exams. Coming late to the class is not accepted(lateness will be evaluated as absent).Student are
not allowed to disturb (talk, eat ,etc...) during the classes.
Academic Dishonesty:
Cheating and plagiarism is prohibited. However, who tries to cheat and plagiaries will receive
one warning but ifshe/he continues to do so it will result in the expulsion from the class and
receive 0 points for that particular exam.
Cheating includes, but is not limited to:








Giving or receiving unauthorized assistance during an examination;
Obtaining unauthorized information about an examination before it is given;
Using inappropriate or unallowable sources of information during an examination;
Falsifying data in experiments and other research;
Altering the record of any grades
Altering answers after an examination has been submitted;
Falsifying any official University record; or,
Misrepresenting the facts in order to obtain exemptions from course requirements.
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Grading policy:
GRADE
S
IUS
GRADES
PERCEN
T
Weight coefficient of IUS grades
A (10)
A
95-100%
4.0
A-
91-94%
3.7
B+
88-90%
3.3
B
85-87%
3.0
B-
81-84%
2.7
C+
78-80%
2.3
C
75-77%
2.0
C-
70-74%
1.7
D+
65-69%
1.3
E (6)
D
55-64%
1.0
F (5)
F
< 55
0.0
B (9)
C (8)
D(7)
Quality assurance:
Quality assurance
Through regular monitoring and control of the assistants the process of continuous work of
students should be achieved. The entire written and oral request from student will be carefully
evaluated by the responsible course holder and through discussion with other professor and
course assistance decisions will be made. Quality of the course will be achieved through
continues homework assignments and tutorials.
Course schedule:
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Week Date/Classroom
1
7.10.2015
No
No
No
1. Elements
2. Structure of the Atom
(13-14h, AF2.13) 3. Isotopes
4. The Periodic Table
 14.10.15
5. Electronic Structure
(11-13h, AF1.11) 6. Electronic Configurations
7. Electronic Configurations and the Periodic
Table
1. Relate the location of an
element inthe periodic table to its
electronic configuration
No lab
activities
No
32-65
3

Chemical compounds properties Tutorialsduring
and binding. It is important to
the lectures
understand their structure and
naming. Additionally Hydrocarbon
organic chemicals will be
introduced, their properties and
use in everyday life. Focus on
health & medicine: covalent drugs
and medical products
Homework 1
93-120

Introduction lecture
Class activities
Readings
Learning
(Book
objectives (After
page
this lesson student
number)
will be able to :
Syllabi review
(11-13h, AF1.11)
2
Topics to be covered
Problems/
Lab activities Assignments
(Homework)
12.10.15
19.10.15
Covalent Bonding and the Periodic Table;
Focus on the Human Body: Covalent
(13-14h, AF2.13)
Molecules and the Cardiovascular System;
Lewis Structures; Drawing Lewis Structures
 21.10.15
; Multiple Bonds;Exceptions to the Octet
(11-13h, AF1.11) Rule;
Elements in Group 3A Elements in the Third
Row ;Resonance; Drawing Resonance
Structures; Focus on the Environment:
Ozone ;Naming Covalent Compounds;
Molecular Shape; Two Groups Around an
Atom etc;Focus on Health & Medicine:
Covalent Drugs and Medical Products
2.Draw an electron-dot symbol for
anAtom
3.Use the periodic table to predict
therelative size and ionization
energy of elements
1.Identify an element by
its symbol and classify it
as a metal, nonmetal,
or metalloid
2. Describe the basic
parts of an atom
3. Distinguish isotopes
and calculate atomic
weight
4. Describe the basic
features of periodic table
5. Understand the
electronic structure
of an atom
6. Write an electronic
configuration for
an element
1.Recognize the bonding
characteristics of
covalent compounds
2.Draw Lewis structures
for covalent compounds
3. Draw resonance
structures for some
ions and molecules
4.Name covalent
compounds that
contain two types of
elements
5. Use electronegativity
to determine whether a
bond is polar or nonpolar
6.Determine whether a
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molecule is polar
or nonpolar
4

26.10.15
Introduction to Organic Chemistry.
(13-14h, AF2.13) Characteristic Features of Organic
(11-13h, AF1.11)
Compounds; Shapes of Organic Molecules;
Drawing Organic Molecules; Functional
Groups; Properties of Organic Compounds

Alkanes

5
28.10.15
2.11.15
Focus on health & medicine:
Vitamins
Focus on Environment:
(13-14h, AF2.13) Introduction
Combustion.

Fossil Fuels
4.11.15
(11-13h, AF1.11)
Simple Alkanes; An Introduction to
Nomenclature; Alkane Nomenclature;
Cycloalkanes
Tutorials during
the lectures
Tutorials during No
the lectures
No
322-354
355-378
1.Recognize the
characteristic features
of organic compounds
2.Predict the shape
around atoms in
organic molecules
3.Use shorthand
methods to draw
organic molecules
4.Recognize the common
functional
groups and understand
their
importance
5. Distinguish organic
compounds from
ionic inorganic
compounds
6. Determine whether an
organic
compound is polar or
nonpolar
7.Determine solubility
properties of organic
compounds
8.Determine whether a
vitamin is fat
1.Identify and draw
acyclic alkanes and
cycloalkanes
2.Identify constitutional
isomers
3.Name alkanes using
the IUPAC system
of nomenclature
4. Predict the physical
properties
of alkanes
5.Write equations for the
complete and
incomplete combustion of
alkanes
5
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6

9.11.15
Monday (Quiz 1)
(13-14h, AF2.13) Wednesday

11.11.15
(11-13h,AF1.11)
Unsaturated hydrocarbons.
Alkenes and Alkynes;Nomenclature of
Alkenes and Alkynes; Cis–Trans Isomers;
Interesting Alkenes in Food and
Medicine;Aromatic Compounds;
Nomenclature of Benzene Derivatives;
Reactions of Aromatic Compounds
FOCUS ON HEALTH &
MEDICINE:
Tutorials during Homework 2
the lectures
379-417
Tutorials during No
the lectures
418-448
Reactions of Alkenes
Margarine or Butter?
Polymers—The Fabric of
ModernSociety:
Aromatic Drugs, Sunscreens,
andCarcinogens:
Phenols as Antioxidants
7

16.11.15
(13-14h, AF2.13)

18.11.15
(11-13h, AF1.11)
8

Organic compounds that contain oxygen,
halogen, or sulfur.
FOCUS ON HEALTH &
MEDICINE:
Structure and Properties of Alcohols.
Ethanol, the Most Widely
Nomenclature of Alcohols; Interesting
Alcohols; Reactions of Alcohols; Structure
and Properties of Ethers; Alkyl Halides;
Organic Compounds That Contain Sulfur
Abused Drug
Ethers as Anesthetics
23.11.15
Monday
(13-14h, AF2.13)
(Project assignments and preparations)

25.11.15
Wednesday
(Non-Working Day)
National Day of BiH (Non-Working Day)
1.Identify the three major
types of unsaturated
hydrocarbons—alkenes,
alkynes, and aromatic
compounds
2.Name alkenes,
alkynes, and substituted
benzenes
3.Recognize the
difference between
constitutional isomers
and stereoisomers, as
well as identify cis and
trans isomers
4. Identify saturated and
unsaturated fatty acids
and predict their relative
melting points
1.Identify alcohols,
ethers, alkyl halides,
and thiols
2. Classify alcohols and
alkyl halides as
1°, 2°, or 3°
3.Determine the
properties of alcohols,
ethers, alkyl halides, and
thiols
4.Give basic names for
alcohols, ethers, alkyl
halides, and thiols
5.Draw the products of
the dehydrationof
alcohols
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9

30.11.15
(13-14h, AF2.13)

2.12.15
(11-13h, AF1.11)
Monday: Aldehydes and Ketone Structure
and Bonding
FOCUS ON HEALTH &
MEDICINE:
Physical Properties; Reactions of Aldehydes
and Ketones; Reduction of Aldehydes and
Ketones; Acetal Formation
Interesting Aldehydes and
Ketones
Wednesday (2.12.2015): MIDTERM EXAM
Tutorials during Homework 3
the lectures
FOCUS ON THE HUMAN BODY
The Chemistry of Vision
Midterm exam will include lecture 1 to 7.
10
Lipids
Fatty Acids; Introduction to Lipids;Waxes;
(13-14h, AF2.13) Triacylglycerol’s—Fats and Oils; Hydrolysis
of Triacylglycerol’s; Phospholipids; Cell
 9.12.15
Membranes

7.12.15
(11-13h,AF1.11)
FOCUS ON HEALTH &
MEDICINE:
Cholesterol, the Most Prominent
Steroid; Steroid Hormones
FOCUS ON HEALTH &
MEDICINE:
Fat-Soluble Vitamins
FOCUS ON HEALTH &
MEDICINE:
Prostaglandins and Leukotrienes
Tutorials during
the lectures
No
473-502
1.Identify the
characteristics of
aldehydes and ketones
2.Name aldehydes and
ketones
3.Give examples of
useful aldehydes
and ketones
4.Draw the products of
oxidation reactions of
aldehydes
5.Draw the products of
reduction reactions of
aldehydes and ketones
6.Understand the basic
reactions involved in
vision
7. Identify and prepare
hemiacetalsand acetals.
579-607 1.Classify fatty acids and
describe the relationship
between melting point
and the number of double
bonds
2.Draw the structure of a
wax and identify the
carboxylic acid and
alcohol components
3. Describe the difference
between a fat and an oils
4. Identify the two major
classes of phospholipids
5. Describe the structure
of a cell membrane, as
well as different
mechanisms of transport
across the membrane
6.Describe the
relationship
between blood
cholesterol level and
cardiovascular disease
7. Define what a
hormone is and list
several examples of
steroid hormones
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8.Identify fat-soluble
vitamins
11

14.12.15
QUIZ 2 (14.12.2015)
(13-14h, AF2.13) Carbohydrates

16.12.15
(11-13h,AF1.11)
12
Monosaccharide’s; The Cyclic Forms of
Monosaccharide’s; Reduction and Oxidation
of Monosaccharide’s; Disaccharides;
Polysaccharides
Amino acids, proteins and enzymes
Introduction; Amino Acids; Acid–Base
(13-14h, AF2.13) Behaviour of Amino Acids; Peptides;
Proteins
 23.12.15
Protein Hydrolysis and Denaturation;
(11-13h,AF1.11) Enzymes

21.12.15
FOCUS ON THE HUMAN BODY:
Useful Carbohydrate Derivatives Tutorials during
FOCUS ON THE HUMAN BODY: the lectures
Blood Type
FOCUS ON THE HUMAN BODY: Tutorials during
Biologically Active Peptides
the lectures
FOCUS ON THE HUMAN BODY:
Common Proteins
FOCUS ON HEALTH &
MEDICINE:
Using Enzymes to Diagnose and
Treat Diseases
Homework 4 608-643
No
644-681
1 Identify the three major
types of carbohydrates
2.Recognize the major
structural features of
monosaccharaides
3.Draw the cyclic forms
of monosaccharide’s
4.Draw reduction and
oxidation products of
monosaccharaides
5.Recognize the major
structural features of
disaccharides
6.Describe the
characteristics of
cellulose, starch, and
glycogen
7.Give examples of some
carbohydrate derivatives
that contain amino
groups, amides, or
carboxylate anions
8.Describe the role that
carbohydrates play in
determining blood type
1.Describe the acid–base
properties of amino acids
2. Draw simple peptides
from individual amino
acids, and label the Nand C-terminal amino
acids
3. Give examples of
simple biologically active
peptides
4.Describe the
characteristics of the
primary, secondary,
tertiary, and
quaternary structure of
proteins
5.Describe protein
denaturation
6. Describe the main
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features of enzymes
7.Describe the use of
enzymes.
Nucleic acids and protein synthesis
FOCUS ON HEALTH &
Nucleosides and Nucleotides;
MEDICINE: Viruses
(13-14h, AF2.13) Nucleic Acids; The DNA Double Helix;
Replication; RNA; Transcription; The
 30.12.15
Genetic Code; Translation and Protein
(11-13h,AF1.11) Synthesis; Mutations and Genetic Diseases;
Recombinant DNA
13

28.12.15
14

4.1.16
(13-14h, AF2.13)

Project presentation by students
Tutorials during
the lectures
Homework 5 682-717
1.Draw the structure of
nucleosides and
nucleotides
2.Draw short segments of
the nucleic acids DNA
and RNA
3.Describe the basic
features of the DNA
double helix4.Outline the
main steps of replication
5. List the three types
and functions of RNA
molecules
6.Explain the process of
transcription
7. Describe the basic
elements of the
genetic code
8. Explain the process of
translation
Each student will present his/her topic in front the classmates.
6.1.16
(11-13h,AF1.11)
18.1.2016 - 29.1.2016
FINAL EXAM PERIOD
Prepared by senior assistant Jasmin Šutković
October 6, 2015
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