Clinical Expert Series Management of Persistent Vaginitis Paul Nyirjesy, MD Obstet Gynecol 2014;124(6) Continuing Medical Education credit is provided through joint sponsorship with The American College of Obstetricians and Gynecologists. ACCME Accreditation The American College of Obstetricians and Gynecologists (the College) is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians. AMA PRA Category 1 Credit(s)™ The American College of Obstetricians and Gynecologists designates this enduring material for a maximum of 2 AMA PRA Category 1 Credits.™ Physicians should claim only the credit commensurate with the extent of their participation in the activity. College Cognate Credit(s) The American College of Obstetricians and Gynecologists designates this enduring material for a maximum of 2 Category 1 College Cognate Credits. The College has a reciprocity agreement with the AMA that allows AMA PRA Category 1 Credits™ to be equivalent to College Cognate Credits. Disclosure Statement Current guidelines state that continuing medical education (CME) providers must ensure that CME activities are free from the control of any commercial interest. All authors, reviewers, and contributors have disclosed to the College all relevant financial relationships with any commercial interests. The authors, reviewers, and contributors declare that neither they nor any business associate nor any member of their immediate families has financial interest or other relationships with any manufacturer of products or any providers of services discussed in this program. Any conflicts have been resolved through group and outside review of all content. Submission Before submitting this form, please print a completed copy as confirmation of your program participation. College Fellows: To obtain credits, complete and return this form by e-mail (obgyn@greenjournal.org) or fax (202-479-0830). Your score, and a copy of the answer key, will be e-mailed to you after receipt of a completed quiz. Credit will be recorded for those participants answering 80–100% of questions correctly. College Fellows may check their transcripts online at http://www.acog.org, and any questions related to transcripts may be directed to educationcme@acog.org. For other queries, please contact the Obstetrics & Gynecology Editorial Office, 202-314-2317 (phone) or obgyn@greenjournal.org (e-mail). Non–College Fellows: To obtain credits, submit the printout of the completed quiz to your accrediting institution. The printout of the completed quiz is documentation for your continuing medical education credits. Continuing medical education credit for “Management of Persistent Vaginitis” will be available through December 2017. 1. A heavy but normal physiologic discharge can be determined by: Serum estrogen level Vaginal bacterial culture Symptom diary Response to empiric progestin therapy Excluding other causes CME Quiz for the Clinical Expert Series Obstet Gynecol 2014;124(6) Credit available through December 2017 Page 1 of 3 2. An effective first choice for many true non-albicans Candida infections is: Weekly oral fluconazole Weekly vaginal clotrimazole Vaginal boric acid Vaginal pH elevation High-dose tinidazole 3. Desquamative inflammatory vaginitis is generally associated with: Non-albicans Candida infections Metronidazole-resistant trichomoniasis Hypoestrogenism Chronic vaginal douching Self-medication 4. For women whom have had symptoms for more than one year, Nyirjesy and colleagues found that which of the following was the most common cause? Localized provoked vestibulodynia Physiologic discharge Contact dermatitis Atrophic vaginitis Trichomoniasis 5. A patient with symptoms of vaginal discharge and itching is found to have a vaginal pH of 4.0. Which of the following is the most likely diagnosis? Bacterial vaginosis Atrophic vaginitis Vulvovaginal candidiasis Trichomoniasis Desquamative inflammatory vaginitis 6. If Trichomonas vaginalis infection is suspected, which of the following is the most reliable method of establishing a diagnosis? Office saline microscopy Vaginal pH measurement Polymerase chain reaction (PCR) Office 10% KOH microscopy Empiric therapy response CME Quiz for the Clinical Expert Series Obstet Gynecol 2014;124(6) Credit available through December 2017 Page 2 of 3 7. The current definition of recurrent vulvovaginal disease includes: Greater than four lifetime infections Symptoms lasting greater than 6 weeks Four or more episodes in a year At least two different organisms on two occasions Recurrence less than 4 weeks after therapy 8. The gold standard for the diagnosis of vulvovaginal candidiasis is: Vaginal pH measurement Polymerase chain reaction (PCR) Yeast cultures with speciation of the organism Office 10% KOH microscopy Clinical examination 9. Which of the following is part of Amsel’s criteria for the diagnosis of bacterial vaginosis? Thick white discharge ≥ 30 white blood cells per high power field on saline microscopy A pH ≥ 4.5 Cocciform bacilli on Gram stain Positive culture for Gardnerella vaginalis 10. A woman who has been using combination oral contraceptives for the past 8 years reports a vaginal discharge described as yellow or brown, along with burning and severe dyspareunia. Examination reveals severe introital and vaginal erythema and a copious vaginal discharge. A number of white blood cells are seen on saline microscopy. The most likely explanation for this patient’s symptoms is: Vulvovaginal candidiasis Lichen sclerosus Occult urinary incontinence Bacterial vaginosis Desquamative inflammatory vaginitis College ID Number: Name: Address: City/State/Zip: E-mail Address: Actual time spent completing this activity (you may record up to 2 hours): CME Quiz for the Clinical Expert Series Obstet Gynecol 2014;124(6) Credit available through December 2017 Page 3 of 3