International J. of Healthcare and Biomedical Research, Volume: 2, Issue: 3 , April 2014 , Pages 24-32
Original article:
Histopathological study of Interface Dermatitis with it’s clinical
correlation
Sushama Desai*, Anuya Badwe*, Balkrishna Nikam**, Saumya Shetty**
Dept. of Pathology* and Dept. of Dermatology**
Krishna Institute of Medical Sciences , Karad , Maharashtra , India
Corresponding author : Dr. Anuya Badwe
Abstract:
Introduction: Interface dermatitis includes numerous skin diseases which have in common a constellation of histo-
pathological features but varied clinical presentation. The present work was planned to correlate significance of Interface
dermatitis with their clinic-pathological aspects.
Methodology: One hundred & twenty clinically suspected cases of interface dermatitis were included in this study. Four mm
punch biopsy was performed along with other necessary investigations. Biopsy specimens were processed. Hematoxylin and
eosin stained sections were studied.
Results : On the basis of clinical and histo-pathological findings the diagnosis of the 120 skin biopsies of interface dermatitis was
as : Lichen planus , Erythema multiforme , Lupus erythmatosus , Lichenoid drug eruptions , Pityriasis lichenoid chronica, Lichen
sclerosis et atrophicus were common. Rest of many others were rare and formed less than 5%.
Conclusion: Interface dermatitis includes etiologically several diverse conditions with histopathologically a common
denominator of Interface Dermatitis. It is important to diagnose clinic-pathologically all these lesions as the prognosis &
treatment varies.
Keywords: Interface dermatitis, histopathology, Haematoxylin and eosin