William Lawrence & Blanche Hughes Foundation January 6, 2015 Dear Colleagues: William Lawrence and Blanche Hughes Foundation in conjunction with the USC Parker Institute for Childhood Cancer Research is accepting grant applications. The goal is to develop novel therapies for childhood acute lymphocytic leukemia. If you know of someone in your institution whose interest dovetails with this aim please make them aware of this funding opportunity. Best regards, H. Phillip Koeffler, M.D. Executive Director 30601 Agoura Road, Suite 200H, Agoura Hills, CA 91301 William Lawrence and Blanche Hughes Foundation (WLBHF) is a non-profit organization whose major goal is to foster discoveries in pediatric acute lymphocytic leukemia (especially B-ALL) with a goal of developing effective therapies for the disease. Applicants must be either an established investigator with an association to an academic institution or must be part of a lab working with an established investigator. Grant applications should be no greater than 7 pages (Includes: Abstract, Background, Experimental Design, Expected Results, Potential Problems). Please use: Point 11 font or greater, Arial, single spaced. Also include: Reference, Detailed Timeline, Budget Justification (Equipment is not included and Education Conferences ≤ $3,000), Other Support and Biosketch (NIH format). Please submit Abstracts of all other grants you have been awarded or currently awaiting their decision. Last year, 29 grants were awarded; emphasis was placed on the translational merits of the proposal. Priority will be given to those grants that have a translational bent on getting new therapies to children with leukemias. Further areas of studies would be to identify new therapeutic targets. Funding: Grants are limited to $150,000/year (direct costs). Indirect costs are limited to 10% per year. Funded grants are reviewed on a yearly basis and those that meet their milestones may be renewed on a yearly basis for up to two subsequent years. Review of grant: All applicants are reviewed by the grant committee and final approval rests with the Board of Directors. Awarding of the grant is based on the priority score and the availability of funds. Send grants electronically to both H.Koeffler@cshs.org and rreed@publicstorage.com. Grant deadline: September 1, 2015, no late applications. Notification of funding decision should occur about December 21, 2015. Funding period January 1, 2016 – December 31, 2016. USC PARKER INSTITUTE FOR CHILDHOOD CANCER RESEARCH IN CONJUNCTION WITH WILLIAM LAWRENCE & BLANCHE HUGHES FOUNDATION GRANT APPLICATION PLEASE USE 11 PT TYPE OR GREATER APPLICANT INFORMATION Project Title: Project Investigator (Name: Last, First, Middle Initial; Degree, Title): Institution, Department: Mailing Address: City: State: Zip: Telephone: Fax: Email: OFFICIAL AUTHORIZED TO SIGN FOR INSTITUTION Name (Last, First): Title: Institution, Department: Mailing Address: City: State: Zip: Telephone: Fax: Email: FISCAL OFFICER Name: Title: Institution, Department: Mailing Address: City: State: Zip: Telephone: Fax: Email: Organization Tax ID: Type (e.g. 501(c)(3)): CERTIFICATION AND SIGNATURES The undersigned has reviewed this application for a USC Parker Institute/William Lawrence & Blanche Hughes grant award. Applicant Name (typed) Signature Date Officer for Institution (typed) Signature Date Fiscal Officer (typed) Signature Date Granting Foundation Approval Signature Date USC PARKER INSTITUTE FOR CHILDHOOD CANCER RESEARCH IN CONJUNCTION WITH WILLIAM LAWRENCE & BLANCHE HUGHES FOUNDATION GRANT APPLICATION PLEASE USE 11 PT TYPE OR GREATER LAY SUMMARY ABSTRACT USC PARKER INSTITUTE FOR CHILDHOOD CANCER RESEARCH IN CONJUNCTION WITH WILLIAM LAWRENCE & BLANCHE HUGHES FOUNDATION GRANT APPLICATION BUDGET FORM (1 YEAR) PERSONNEL (DIRECT COSTS ONLY) Percent Effort Name Role on Project Salary on Project Fringe Sub Total (Personnel): EQUIPMENT Description Cost Budget Total Sub Total (Equipment): SUPPLIES Description Cost Budget Total Sub Total (Supplies): OTHER Description MAX TOTAL DIRECT COSTS Cost Sub-Total (Other): $ MAX TOTAL INDIRECT COSTS (NOT TO EXCEED 10% OF GRANT REQUEST) MAX GRAND TOTAL $ $ Budget Total: Budget Total