Appendix 2
National and international collaboration partners and ongoing projects
Professor Carina B. Johansson, Department of Prosthodontics/dental materials science,
Institute of Odontology, the Sahlgrenska Academy, University of Gothenburg.
An ongoing project deals with enamel mineralization in teeth from infants diseased in
“sudden infant death syndrome”. Further studies are planned in connection to enamel
reactions to dental materials and regarding hardness measurements of the enamel
surface after demineralization and remineralization studies.
Professor Peter Lingström, Department of Cariology, Institute of Odontology, the Sahlgrenska
Academy, University of Gothenburg.
Cooperation in a PhD project regarding dentin caries detection systems, morphological
and chemical aspects utilizing POLMI, FTIR and ToF-SIMS. Involved in the project are
Ulrica Almhöjd (PhD student), JG. Norén, N. Sabel and L. Melin.
Dr. Fabian Taube PhD, Department of Occupational and Environmental Medicine,
Sahlgrenska University Hospital, Gothenburg, Sweden. Dr. Taube is an environmental
chemist and has since several years been involved in in vitro studies of enamel reactions to
alkaline agents and to organic solutions (Taube et al., 2010a; 2010b; Taube et al., 2013).
Ongoing projects with Dr. Taube (including JG. Norén, N. Sabel and L. Melin)
focuses on analysis of the organic components in normal and hypomineralized enamel
using Raman Fourier Transform Spectroscopy, Diffuse Reflectance Infrared Fourier
Transform Spectroscopy (DR-FTIR) and X-ray diffraction (XRD).
Projects regarding the reactivity of the enamel to organic solvents are planned since
exposure to organic solvents is an identified occupational problem.
Professor David Cornell, Department of Earth sciences, University of Gothenburg,
Gothenburg, Sweden. Professor Cornell is a geologist specialized in mineralogy, thus having
knowledge in mineral analysis which is well suitable for analysis of dental hard tissues (Melin
et al., 2013a; Melin et al., 2013b).
Ongoing projects with Professor Cornell deals with development of quantitative XRMA
methods for elemental analysis of dental hard tissues and improved SEM-imaging of
dental hard tissues. The scientific knowledge in mineralogy forms an inter-scientific
research area of importance for research on dental hard tissues. Analysis with XRMA and
SEM at the Department of Earth sciences is based on own handling of the instrument
after thorough instructions and training.
Dr. GR. Davis, Institute of Dentistry, Barts and The London School of Medicine and
Dentistry, Queen Mary University of London, London, United Kingdom and Dr. JM. Fearne,
Department of Paediatric Dentistry, Royal London Hospital, London, United Kingdom.
Dr. Davis is a specialist in X-ray micro computed tomography and has developed new high
resolution instruments and software for X-ray 3D imaging.
Dr. JM. Fearne is a specialist in Pediatric Dentistry with research fields related to caries and
developmental disturbances. Dr. Fearne collaborates in her research with Dr. GR. Davis.
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Appendix 2
Ongoing projects with Dr. Davis and Dr. Fearne (involving JG. Norén and N. Sabel)
deals with XMCT-imaging of dental hard tissues, specifically dentinogenesis imperfecta
Type II (Davis et al, 2013). Planned projects concern 3D imaging of artificial and
natural caries in enamel.
Dr. Sebastian Paris, Universitätsklinikum Schleswig-Holstein, Christian-AlbrechtsUniversität Kiel, Kiel, Germany. Dr. Paris is involved in in vitro and in vivo studies on low
viscous resins and its applications for treatment of hypomineralized enamel and white spot
lesions. Analyses are performed with transversal microradiography, SEM polarized light
microscopy and confocal microscopy.
Ongoing projects with Dr. Paris are in vitro experiments with resin infiltration of
hypomineralized enamel in teeth diagnosed MIH. The results have so far proven to be
successful and in vivo studies for treatment of MIH teeth, fluorotic enamel and white
spot lesions are planned. In vitro studies are also planned to evaluate the long term
effect of resin infiltration to acid environments.
Professor Patrick Mahoney, University of Kent, Canterbury, England. Professor Mahoney is
involved in a project concerning morphological analysis of enamel where the relation between
incremental lines and postnatal growth and development is studied.
Professor Mahoney has developed special techniques for preparing very thin sections of
un-demineralized dental hard tissues which is essential for evaluation of incremental
lines in the enamel enabling exact dating of the growth pattern of the enamel. Ongoing
projects on primary teeth include evaluation of the growth pattern of the enamel in
relation to the general somatic growth in normal children and children born very
preterm.
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