HBC 107 (ORGANIC CHEMISTRY FOR BIOCHEMISRY STUDENTS) Introduction: The course is designed to provide the basic knowledge on the principles or Organic Chemistry to Biochemistry students of the University of Nairobi. Programme: BSc in Biochemistry LECTURER: PROFESSOR ABIY YENESEW OFFICE: G6 (Chemistry Department, Chiromo Campass) ayenesew@uonbi.ac.ke; abiyenesew@yahoo.com TIME TABLE Monday Thursday Friday 8.00-10.00 (Lecture) 14.00-17.00 (Lab) 11.00-13.00 (Lecture) Venue: Small Lecture Theatre ( SLT) Consultation Hours Tuesday Wednesday Thursday 16.00-17.00 16.00-17.00 16.00-17.00 Course objectives: To provide the basic knowledge in Organic Chemistry Instructional methods (per week): 3 hours of lectures, three hours of practicals and one hour of tutorials COURSE EVALUATION: • Assignments and tutorials (5 MARKS) • CAT (10 MARKS) • Practical (15 MARKS) • Final Exam (70 MARKS) RECOMMENDED BOOKS (HBC 107): 1) Organic Chemistry by John McMurry, Brooks/Cole Thomson Learning 2) Organic Chemistry by F. Carry 3) Organic Chemistry by By H. Hart, L.E. Craine and David J.Hart, Houghton Mifflin Company, Boston, New York 4) Organic Chemistry by T.W.G. Solomons John Wiley & Sons, Inc. New York, Chichester 5) Organic Chemistry by Clyden, Greeves, Warren and Wothers, Oxford University Press COURSE OUTLINE 1. What is Organic Chemistry? 2. Carbon in the periodic table. 3. Bonding in carbon compounds – ionic bond, covalent bond and hybridization. 4. Polar Covalent Bonds: Electronegativity, dipole moment. 5. Intermolecular forces. 6. Nomenclature, isomerism in alkanes, conformational isomers, occurrence, uses, preparation and reactions of alkanes. 7. Introduction to functional groups 8. An Overview of organic reactions: Addition, substitution, elimination, rearrangement. Basic concepts of organic reaction mechanisms. 9. Inter-conversion of functional groups (alcohol to alkyl halide, ether, carbonyl, carboxylic acid etc). 10 Introduction to stereochemistry: Optical isomers (stereoisomerism and enantiomerism).